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6641822 |
Composition containing humidity regulators for preparing tissue products
A composition is provided containing moisture regulators for tissue products. The composition contains 1% to 15% by weight, preferably 2% to 20% by weight, relative to the total composition, of at...
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6641831 |
Medical products with sustained pharmacological activity and process for producing them
A non-degradable medical product comprising at least two substances or groups of substances, of which a first substance is referred to as substance A and a second is referred to as substance B,...
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6641843 |
Pharmaceutical compositions
The present invention relates to pharmaceutical compostions of (1S,4R)-cis-4-[2-amino-6-cyclopropylamino}-9H-purin-9-yl]-2-
cyclopentene-1-methanol (1592U89).
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6635280 |
Extending the duration of drug release within the stomach during the fed mode
Drugs are formulated as unit oral dosage forms by incorporating them into polymeric matrices comprised of hydrophilic polymers that swell upon imbibition of water to a size that is large enough to...
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6632446 |
Coating substrates by polymerizing macromers having free radical-polymerizable substituents
Water soluble macromers are modified by addition of free radical polymerizable groups, such as those containing a carbon-carbon double or triple bond, which can be polymerized under mild conditions...
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6630168 |
Gel delivery vehicles for anticellular proliferative agents
Methods and compositions are provided for the treatment of a host suffering from a cellular proliferative disease. In the subject methods, antiproliferative agents are administered in a...
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6630154 |
Polymer formulations containing perfluorinated compounds for the engineering of cells and tissues for transplantation that improves cell metabolism and survival, and methods for making same
Disclosed and claimed are: a composition including at least one glycosaminoglycan, e.g., CIS, at least one perfluorinated substance and at least one alginate, e.g., sodium alginate, wherein: the...
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6627226 |
Dry solid medium for storage and analysis of genetic material
The present invention provides for device for obtaining and storing genetic material. The device has a support and a head portion. The head portion is composed of a solid matrix for sorbing genetic...
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6624300 |
Method for concentrating beta-glucan film
An entirely aqueous method for concentrating beta-glucan from a beta-glucan source, such as milled cereal bran, grain or distiller's dried grain. The method comprises providing an alkaline aqueous...
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6620435 |
Compositions for topical application of therapeutic agents
The present invention generally relates to pharmaceutical compositions that enable control of drug, delivery properties and the development of optimal drug delivery strategies customized for...
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6620432 |
Phenytoin sodium pharmaceutical compositions
A pharmaceutical composition is provided containing an admixture of phenytoin sodium and an erodible matrix which extends the release of the phenytoin sodium over about a two hour period. The...
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6616937 |
Cosmetic composition containing a distillate of a green plant juice and a process for preparing the same
An improved cosmetic composition comprises at least one cosmetically effective ingredient and water, where at least a potion of the water has been replaced by a distillate of a green plant juice....
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6607751 |
Controlled release delivery device for pharmaceutical agents incorporating microbial polysaccharide gum
The present invention provides a controlled release device for sustained or pulsatile delivery of pharmaceutically active substances for a predetermined period of time. This invention further...
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6607748 |
Cross-linked high amylose starch for use in controlled-release pharmaceutical formulations and processes for its manufacture
The present invention relates to a novel form of cross-linked high amylose starch and processes for its manufacture. Such cross-linked high amylose starch is useful as an excipient in a...
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6599530 |
Oral compacted composition comprising catechol derivatives
The present invention relates to an oral compacted composition comprising entacapone, nitecapone, or a pharmaceutically acceptable salt thereof and croscarmellose sodium. The composition is...
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6596293 |
Polyurethane-biopolymer composite
A method is provided for preparing a drug delivery material and device comprising cross-linking a biological polymer with a cross-linking agent and loading the cross-linked biopolymer with a...
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6596308 |
Controlled release pharmaceutical composition
A sustained/prolonged release pharmaceutical dosage form is disclosed. The form comprises a hard shell capsule and a formulation comprising (a) a water insoluble medicant, (b) a high melting fatty...
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6592898 |
Bioadhesive compositions comprising hydrophobic polymers
Bioadhesive compositions which comprise a hydrophobic polymer wherein the concentration of the polymer at the surface of the adhesive is greater than its concentration in the bulk of the adhesive...
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6589558 |
Photoablatable lenticular modulator
Photoablatable modulator for use in Laser ablation processes on the cornea consisting of a mixture of collagen and vegetable gelatins which is formed in situ on the corneal surface to be treated. A...
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6589556 |
Rapid-melt semi-solid compositions, methods of making same and methods of using same
A novel rapid-melt, semi-solid molded composition, including methods of making the same, and methods of using the same for the delivery of prophylactic and therapeutic active materials to a mammal...
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6589546 |
Polymeric coatings for controlled delivery of active agents
Implantable medical device having a structure adapted for introduction into a patient wherein the structure is composed of a base material positioned over the structure. The implantable medical...
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6586493 |
Polysaccharide-based hydrogels and pre-gel blends for the same
Disclosed are hyaluronate-containing hydrogels having angiogenic and vascularizing activity and pre-gel blends for preparing the hydrogels. The hydrogels contain a cross-linked matrix of a...
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6586011 |
Microencapsulated plasminogen activators
A drug delivery system which includes a plurality of microcapsules, each microcapsule containing a plasminogen activator entrapped in a biocompatible, biodegradable, substantially water-soluble...
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6582718 |
Cyclosporin compositions
An ophthalmic composition particularly in the form of eye-drops suitable for the treatment of diseases of the eye and surrounding areas. The composition contains a cyclosporin and a surfactant...
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6576261 |
Potentiation of inclusion complex formation of cyclodextrin derivatives
A method is disclosed for the potentiation of formation of inclusion complexes of electroneutral and anionic compounds. Included are compositions containing complexes of two different cyclodextrin...
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6565877 |
Taste masked compositions
A taste masked composition which comprises a bitter tasting drug, a combination of two enteric polymers comprising, a methacrylic acid copolymer and a phthalate polymer is described. The...
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6565883 |
Controlled release oral compositions comprising rivastigmine
Pharmaceutical composition capable of releasing a therapeutically effective dose of active agent, e.g., rivastigamine, in a time-controlled manner.
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6565872 |
Polymeric system for drug delivery and solute separation
Described is a composite polymeric system to provide enhanced stimuli-responsiveness. The first aspect provides particles where the particles are made of stimuli-responsive polymer which responds...
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6562961 |
Aminoalkyl trialkyl silyl cellulose and a method for coating surfaces
The invention relates to polysaccharide derivatives comprising a) at least one hydrophobic and b) at least one nitrogen-containing substituent; in particular, the derivative is a cellulose ether...
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6562361 |
Pheromone immobilized in stable hydrogel microbeads
A microbead comprising pheromone encapsulated in a coacervate shell is provided. The coacervate shell is entrained in a hydrogel microbead without chemical crosslinking. The microbeads of the...
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6558696 |
Desoxypeganine
The invention relates to a transdermal therapeutic system (TTS) containing desoxypeganine (1,2,3,9-Tetrahydropyrrolo[2,1-b]quinazoline) as the active component, wherein the TSS includes a back...
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6558694 |
Zinc chloride unit dose packaging, applicator, and method of use in treating cancer and other skin diseases
An improved method for the treatment of melanoma and skin diseases which utilizes a zinc chloride fixative mixture is provided. The active ingredients of the fixative mixture include zinc chloride...
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6555525 |
Microencapsulation and sustained release of oligonucleotides
This invention relates to a composition, and method of forming and using the composition, for the sustained release of oligonucleotides, in particular antisense ODNs. The sustained release...
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6552024 |
Compositions and methods for mucosal delivery
Mucosal surface-coat-forming film dosage units containing a water-soluble hydrocolloid, an effective dose of an active agent and a mucosal adhesion enhancer; wherein the active agent is...
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6551622 |
Dry powder compositions
A hydrophilic therapeutic agent is prepared in storage-stable form, suitable for administration to a patient. The agent is formulated with a hydrophobically-derivatized carbohydrate, making use of...
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6548555 |
Basic drug compositions with enhanced bioavailability
A composition comprising a basic drug, a drug which forms a zwitterion, or a salt of either entity, admixed with a polymer selected from hydroxypropylmethylcellulose acetate succinate (HPMCAS),...
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6548083 |
Prolonged release active agent dosage form adapted for gastric retention
The present invention is directed to an active agent dosage form which is adapted for retention in the stomach and useful for the prolonged delivery of an active agent formulation to a fluid...
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6541026 |
Nutritional composition, methods of producing said composition and methods of using said composition
Nutritional compositions comprising aloe vera, hydrolyzed collagen, garcinia cambogia, chromium polynicotinate, chromium picolinate, chromium cruciferate, conjugated linoleic acid, fiber and...
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6534085 |
Phytochemicals for promoting weight loss
New dietary supplement compositions are disclosed that comprise the phytochemical Diindolylmethane (DIM), as well as its precursor, Indole-3-carbinol (I3C), and cogener, 2-(Indol-3-ylmethyl)-3,3′...
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6534090 |
Oral osmotic controlled drug delivery system for a sparingly soluble drug
The present invention is for an oral osmotic controlled drug delivery system for a sparingly soluble drug comprising: a. a core comprising (i) finely particulate anhydrous carbamazepine (ii) a...
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6531154 |
Modulated release from biocompatible polymers
Sustained delivery compositions which modulate the release of incorporated prophylactic, therapeutic, and/or diagnostic agents, and methods of preparation and use thereof, are disclosed. The...
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6531153 |
Composition with sustained release of levodopa and carbidopa
The invention relates to a pharmaceutical composition comprising a therapeutically effective amount of levodopa and of carbidopa, dispersed in a hydrophilic matrix, said composition further...
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6528088 |
Highly flexible starch-based films
Film-forming compositions are disclosed that can comprise, on a dry solids basis, 25 to 75 percent by weight of certain starch derivatives and 25 to 75% primary external plasticizer. The starch...
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6528073 |
Solid cosmetic composition and uses thereof
A solid composition for topical application comprising, in an aqueous phase, a gelling system comprising (i) gellan gum, (ii) at least one other hydrocolloid chosen from the group formed by xanthan...
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6524607 |
Formulations and methods for providing prolonged local anesthesia
A formulation and methods for inducing sustained regional local anesthesia in a patient comprising a substrate comprising a local anesthetic and an effective amount of a biocompatible,...
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6524618 |
Directly compressible extended-release matrix formulation for metformin hydrochloride
An extended-release matrx formulation capable of being directly compressed into tablets comprising metformin hydrochloride blended with specific excipients. The excipients used in the formulation...
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6524611 |
Compositions containing creatine and creatinine
A composition for human consumption, comprising creatine and creatinine, the latter being in sufficient quantity to render creatine in an aqueous medium substantially stable, and a method of making...
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6521254 |
Single-dose antihistamine/decongestant formulations for treating rhinitis
Pharmaceutical dosage forms for oral administration of an antihistamine and a decongestant are disclosed. The dosage forms provide an antihistamine in an amount and formulation to exhibit...
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6521253 |
Immediate release tablet
A new oral IR formulation in solid form for a low molecular weight thrombin inhibitor having pH dependant dissolution, characterized in that the formulation comprises a filler or a combination of...
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6517858 |
Bioactive prostheses with immunosuppressive, antistenotic and antithrombotic properties
The invention relates to a bioactive implant comprising a substrate coated with a polymer layer with reactive functions, and a bioactive substance fixed on the implant by means of said reactive...
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