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5578307 Shaped articles containing plant extract(s), in particular pellets, and their pharmaceutical or cosmetic use  
Shaped articles containing plant extract(s), in particular pellets, are formed by dispersing the plant extract(s) in a matrix predominantly composed of a skeleton builder, i.e. collagen, gelatin,...
5578305 Methods and preparations for preventing adhesions to organs and parts of organs  
Pharmaceutical composition for prevention of adhesions to body organs or parts of body organs within a body cavity at a site of inflammation is disclosed. The pharmaceutical composition contains...
5576024 Buffered matrix aspirin  
A buffered aspirin tablet composed of a uniform mixture of aqueous-based polymer coated aspirin, a buffering system and a hydrophillic gel-forming matrix material. The buffering system and matrix...
5573783 Redispersible nanoparticulate film matrices with protective overcoats  
A pharmaceutical film matrix comprising nanoparticles of a low solubility drug associated with a steric stabilizer and a film dispersing agent is coated on the surface of carrier particles and...
5571534 Drug formulations for parenteral use  
This invention relates to parenteral preparations of antiestrogens such as toremifene, desmethyl toremifene, tamoxifen or desmethyltamoxifen. The preparations can be emulsions, liposomes or aqueous...
5571531 Microparticle delivery system with a functionalized silicone bonded to the matrix  
A particulate carrier for an agent comprising a solid core of a polysaccharide and a proteinaceous material and an organometallic polymer bonded to the core is provided. The agent has a biological...
5569468 Vaccine delivery system for immunization, using biodegradable polymer microspheres  
A controlled release oral formulation, for human vaccines, are formed in microspherical form. The vaccine is suspended in a polymer matrix. The polymer matrix is formed from at least two highly...
5567440 Methods for modifying cell contact with a surface  
Described herein is a multi-functional polymeric material for use in inhibiting adhesion and immune recognition between cells and cells, cells and tissues, and tissues and tissues. One component of...
5567439 Delivery of controlled-release systems(s)  
The present invention is a method and a dosage unit for delivery of a controlled-release system. The dosage unit is a quick dissolve unit which can be prepared by mixing uncured shearform matrix...
5565443 Subcutaneous implants based on normegestrol derivatives  
Subcutaneous implant for preventing conception for at least one year in women comprising an amount effect to prevent conception without suppressing intermontly bleeding of a steroid compound of...
5565407 Biologically active agent encapsulated in biodegradable starch/polymer matrices  
Improved release-extending compositions are provided for encapsulation of bioactive agents which exhibit reduced release rates of the bioactive agent from the composition matrix when compared with...
5562923 Process for conditioning of water-soluble substances  
A process for providing water-soluble micronized pharmaceutically acceptable inhalable substances, which can be produced, stored and used while maintaining the aerodynamic properties required for...
5560930 Method for preparing aqueous emulsion for coating solid pharmaceutical preparations  
A method permits the easy preparation of an aqueous emulsion for coating solid pharmaceutical preparations through emulsification in water without addition of additives such as emulsifying agents,...
5560932 Microprecipitation of nanoparticulate pharmaceutical agents  
This invention describes the preparation of nanoparticulate pharmaceutical agent dispersion via a process that comprises the dissolution of the said pharmaceutical agent in an alkaline solution and...
5558861 Modified microbially-produced cellulose gel with human epidermal cells adsorbed thereon for use as a skin graft or vulnerary cover  
Disclosed is a gel of microbially-produced cellulose, characterized in that the microbially-produced cellulose is modified by (1) physically or chemically bonding an animal cell adhesive protein to...
5554386 Delivery of therapeutic agents to receptors using polysaccharides  
This invention relates to a method of directing a therapeutic agent to selected cells, wherein a complex is formed between a polysaccharide capable of interacting with a cell receptor and a...
5554577 Agents for the stimulation and cultivation of plant growth and process for producing said agents  
The subject matter comprises shaped mixtures of valuable materials for the stimulation and cultivation of plant growth, said materials containing plant nutrients and/or plant-protective agents in...
5552159 Solid depot drug form  
A solid depot drug form produced by melt extrusion at from 50° to 200° C. and continuous shaping of a mixture of from 0.1 to 70% by weight, based on the finished depot form, of a pharmaceutical...
5550178 Process for encapsulating biologics using crosslinkable biocompatible encapsulation system  
Crosslinked biocompatible compositions comprising an ionically crosslinked component and a covalently crosslinked component for encapsulating biologics are disclosed. In accordance with the present...
5545414 Cholesterol lowering food product  
A nutritional product having a solid matrix containing protein, fat and carbohydrate has disposed therein particles of dietary fiber encapsulated in zein. The preferred dietary fiber is guar. Such...
5541304 Crosslinked hydrogel compositions with improved mechanical performance  
This invention provides a method of altering the water content of a hydrogel comprising treatment of said hydrogel with a liquid dehydrating composition. There is further provided a method of...
5536505 Controlled release matrix system using cellulose acetate/poly-2-ethyl-2-oxazoline blends  
This invention relates to a controlled release matrix system comprising a homogenous mixture of poly-2-ethyl-2-oxazoline, cellulose acetate having a degree of substitution for acetyl of from about...
5532305 Controlled release preparation for bioactive substances  
To provide a base suitable for a controlled release preparation and the controlled release preparation. A bioactive substance(s) is introduced in a poly-ion complex of hyaluronic acid and a...
5531735 Medical devices containing triggerable disintegration agents  
The invention discloses temporary medical devices such as stent implants which can be disintegrated in-vivo upon demand by release of an agent held trapped within the device. The device is...
5530112 Gel production from plant matter  
A method of producing a gel material and which comprises firstly providing an aqueous soluble hemicellulosic starting medium which is free of glucans and obtainable from testaceous plant material....
5527542 Process for sugarless coating and products obtained according to the process  
The present invention relates to a process for coating with maltitol making it possible easily and rapidly to create a coating on the surface of a product. This process consists, on the one hand,...
5525358 Gel film-forming flexible collodion compositions  
Gel film-forming flexible collodion compositions can be improved by including one or more topically acceptable polymers in an amount sufficient to increase the resilience of the film formed....
5520928 Pharmaceutical composition of ticlopidine hydrochloride  
A pharmaceutical composition which comprises ticlopidine hydrochloride together with stearic acid and other suitable pharmaceutical excipients, and which does not contain any organic acid other...
5519020 Polymeric wound healing accelerators  
The invention describes water insoluble polymeric NONOate complexes which are capable of accelerating wound repair through the controlled therapeutic release of NO. The composition is additionally...
5514379 Hydrogel compositions and methods of use  
Biocompatible, biodegradable, hydrogels are prepared from a backbone bonded to a cross-linking agent. Suitable backbones include proteins and polysaccharides, e.g,, albumin, polymannuronic acid, or...
5512290 Compositions containing 2-acetyl-1-pyrroline  
A powder-form composition of 2-acetyl-1-pyrroline incorporated with a support of maltodextrin and/or cyclodextrin. The composition is prepared by hydrolyzing a 2-(1-alkoxyethenyl)-1-pyrroline with...
5512289 Spermicidal anti-viral lubricant composition and method of using same  
A personal lubricant composition containing an antiviral, alkylphenoxypolyethoxyethanol spermicide, a water soluble polymer gel matrix and a solubilizer which permits the spermicide to be...
5512302 Pharmaceutical process using starch  
A process for the preparation of a pharmaceutical composition in the form of agglomerates comprising 70-97% by weight of 2-(4-isobutylphenyl)propionic acid or a pharmaceutically acceptable salt...
5510118 Process for preparing therapeutic compositions containing nanoparticles  
A process of preparing nanoparticulate drug substances comprising the steps of: preparing a premix of the drug substance and a surface modifier, and subjecting the premix to mechanical means to...
5508042 Controlled release oxycodone compositions  
A method for substantially reducing the range in daily dosages required to control pain in approximately 90% of patients is disclosed whereby an oral solid controlled release dosage formulation...
5503848 Spongy material consisting essentially of hyaluronic acid or its derivatives, and its use in microsurgery  
The present invention relates to a new spongy material consisting essentially of hyaluronic acid or its derivatives. The characteristics of the new pharmaceutical preparations consist in assuring...
5503847 Hydrocolloid wound gel  
A hydrocolloid wound gel composition useful for cleansing an debriding wounds and having some capacity for absorbing wound exudate and a method of treating wounds comprising applying the...
5496562 Solid medium and method for DNA storage  
A solid medium for storage of DNA, including blood DNA, comprising a solid matrix having a compound or composition which protects against degradation of DNA incorporated into or absorbed on the...
5492700 Process and composition for the development of controlled release gemfibrozil dosage form  
Gemfibrozil formulations prepared from a single granulation of gemfibrozil and a release-control agent are disclosed. The release-control agent is present in an amount sufficient to provide both...
5490991 Directed delivery of radioprotectants using a receptor specific carrier  
Chemoactive radioprotectants are coupled to carrier molecules capable of binding cell receptors to form complexes that can be directed to specific non-target cells in a mixture of cells prior to...
5489437 Hydrogel products and methods of producing same  
An adhesive hydrogel product includes a mixture comprising water, and a thermoplastic, water-soluble polymer extruded in a dry state. The thermoplastic, water-soluble polymer constitutes the...
5486364 Readily available konjac glucomannan as a sustained release excipient  
A solid dosage form, such as a pharmaceutical tablet, containing a rapidly hydratable konjac glucomannan sustained release excipient such as clarified konjac, cryogenically ground konjac and...
5478572 Gepirone dosage form  
Gepirone compositions having extended release properties contain a gepirone salt, a cellulosic polymer matrix and suitable quantities of pharmaceutical excipients. Dosage forms based thereon...
5478576 Arabinogalactan derivatives and uses thereof  
A substantially purified arabinogalactan, its degradative products and selected modifications thereof have been found to act as carriers for delivering therapeutic agent to cell receptors capable...
5478575 Polymers having benzeneboronic acid groups and insulin complexes of same of a sugar response type  
The present invention provides a polymer complex of a sugar response type having boronic acid groups in the polymer. Medicines may be contained or linked, preferably, the medicines have hydroxy...
5478837 Use of quinacrine in preventing adhesion formation  
Compositions and methods for prevention of adhesion formation, whereby an effective amount of quinacrine as active agent is administered for a period of time sufficient to permit tissue repair. The...
5478571 Process for the preparation of substantially alcohol free pharmaceutical compositions  
A novel process for the preparation of pharmaceutical compositions involving the stabilization of the active drug(s) through the reduction of residual alcohol present in a drug/carrier blend. The...
5476668 Base for film-coating pharmaceuticals and method for preparing same  
A cellulose ether having a low degree of polymerization is used as a base for film-coating pharmaceuticals. The cellulose ether having a low degree of polymerization obtained by causticizing a pulp...
5476665 Azlactone functional particles incorporated in a membrane formed by solvent phase inversion  
A composite membrane is provided having covalently azlactone functional particles incorporated in a membrane formed by solvent phase inversion. The azlactone functional particles have surfaces of...
5472704 Pharmaceutical controlled-release composition with bioadhesive properties  
A pharmaceutical composition for the controlled release of medicinal drugs, which has the property of adhering to biologic tissues is described. The characteristic features of the composition are a...