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5656294 |
Colonic delivery of drugs
Pharmaceutical compositions for orally delivering a therapeutically effective amount of a drug to the colon without significant release of the drug in the upper GI tract after oral administration...
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5656298 |
Immunobooster for delayed release of immunogen
An immunobooster capable of delivering an immunogen to an individual or animal in a controlled release manner is described. The immunobooster contains an immunogen/hydrophobic polymer matrix with a...
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5654006 |
Condensed-phase microparticle composition and method
An microparticle composition and its method of use in drug delivery and diagnostic applications are disclosed. Also disclosed are methods of storing and administering drug compounds at high...
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5654002 |
Piroxicam tablets and production and process thereof
A process is provided for the production of piroxicam tablets. According to the process, a solution of a water-soluble high-molecular substance is added to a mixture of piroxicam and lactose. The...
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5651987 |
Ulcer prevention and treatment composition
Anti-ulcer compositions are disclosed having therapeutic agents dispersed in a soluble matrix formed by melt spinning the therapeutic agent with a carrier and hydrogel. Methods of treating...
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5648093 |
Pharmaceutical and other dosage forms
A fast dissolving, solid dosage form defined by a matrix containing gelatin, pectin and/or soy fiber protein and one or more amino acids having from about 2 to 12 carbon atoms is disclosed.
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5646205 |
Ion complex membrane and a method for producing same
An ionomer for an ion complex membrane useful for the separation of water-organic solvent by osmosis or low pressure osmosis as well as by pervaporation and a method for producing ion complex...
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5645903 |
Solid o/w-type cosmetic composition
A solid o/w-type cosmetic composition, a process for molding it, and a container used for aqueous-type solid cosmetics are disclosed. The cosmetic composition comprises (a) a water-soluble...
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5643603 |
Composition of a bioadhesive sustained delivery carrier for drug administration
A composition of a bioadhesive carrier for a prolonged, sustained and controlled delivery of a drug having a local or systemic action contains pregelatinized or thermally modified, food accepted...
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5641516 |
Compositions which contain active substances and are in the form of solid particles
Compositions which contain active substances and are in the form of solid particles can be obtained by intimately mixing the active substance with a water-soluble melt composed of a) 10-90% by...
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5639473 |
Methods for the preparation of nucleic acids for in vivo delivery
In accordance with the present invention, there are provided compositions useful for the in vivo delivery of a biologic, wherein the biologic is associated with a polymeric shell formulated from a...
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5637313 |
Chewable dosage forms
Disclosed is a soft, chewable dosage form, including a matrix of hydrogenated starch hydrolysate, a water soluble bulking agent, and a water insoluble bulking agent. The present invention also...
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5635520 |
Anti-ulcer compositions suitable for rectal administration
The present invention relates to a composition for rectal administration which comprises a benzimidazole compound having antiulcer activity and a salt of C 6 -20 fatty acid, both of which are...
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5635209 |
Stabilized composition of levothyroxine sodium medication and method for its production
The invention discloses a medication which requires the combination of levothyroxine sodium and potassium iodide, with the potassium iodide acting as a stabilizing excipient, the presence of which...
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5633015 |
Beads having a core coated with an antifungal and a polymer
The present invention is concerned with beads comprising a 25-30 mesh core, a coating of a hydrophilic polymer and an antifungal agent, and a seal outer coating layer; pharmaceutical dosage forms...
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5629018 |
Composition for controlled release of an active substance and method for the preparation of such a composition
In a composition for delayed release of an active substance, the active substance is incorporated in a polysaccharide matrix which consists of an essentially crystalline straight-chain glucan and...
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5629003 |
Rapidly disintegrating sheet-like presentations of multiple dosage units
A presentation which, in the form of a film, permits the individual dosage of drugs, confectionary, other food, cosmetics and the like for oral application or intake. The presentation is...
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5629191 |
Method of making a porous matrix particle
A porous particle having a generally isopycnic density with liquid growth medium, a sponge-like character and a diameter of less than 2 mm which is formed from a homogenous biologically compatible...
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5624685 |
High polymer gel and vascular lesion embolizing material comprising the same
The improved vascular lesion embolizing material comprises a high-polymer gel capable of absorbing water in an amount of 10 ml/g and more. The high-polymer gel is preferably such as is produced by...
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5624684 |
Enzyme systems
Enzyme products are disclosed. The enzyme products include an enzyme-bearing matrix formed by subjecting a feedstock containing enzyme(s) and carrier materials to conditions which alter the...
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5624686 |
Feed additives for fattening pigs, feed for fattening pigs, and method of fattening pigs
Feeding fattening pigs a feed additive which contains as an active ingredient active folic acid (in the form of leucovorin, H 2 -folic acid, a liver powder, disrupted cells of a microorganism or a...
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5624940 |
Aqueous solution inclusion complexes of benzothiophene compounds with water soluble cyclodextrins, and pharmaceutical formulations and methods thereof
The present invention provides aqueous inclusion complexes of certain known benzothiophene compounds, particularly Raloxifene, and water soluble cyclodextrins. Also provided are pharmaceutical...
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5622718 |
Alginate-bioactive agent conjugates
The invention is an alginate-bioactive agent conjugate connected via an acid labile biodegradable spacer linkage. The conjugate is effective for delivering bioactive agents to targets existing in...
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5622707 |
Composite membranes for the guided regeneration of tissues
Biomaterials are disclosed comprised of biodegradable, biocompatible, and bioabsorbable composite membranes for use in surgery for the guided regeneration of tissues. The composite membranes are...
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5623064 |
Poly-β-1➝-4-N-acetylglucosamine
The present invention relates to a purified, easily produced poly-β-1➝4-N-acetylglucosamine (p-GlcNAc) polysaccharide species. The p-GlcNAc of the invention is a polymer of high molecular weight...
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5622717 |
Ulcer prevention method using a melt-spun hydrogel
Anti-ulcer compositions are disclosed having therapeutic agents dispersed in a soluble matrix formed by melt spinning the therapeutic agent with a carrier and hydrogel. Methods of treating...
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5620706 |
Polyionic insoluble hydrogels comprising xanthan and chitosan
A method for the preparation of insoluble hydrogels from the complexation of polycations and xanthan is reported. Stable hydrogels capable of retaining between 65 and 95 % weight water were...
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5618562 |
Spherical granule, production method thereof and medicinal preparation using said granule
The spherical granules useful as a precipient for medicines and foods, and a production method thereof. A spherical granule comprises 95% by weight or more of lactose, and has a long diameter/short...
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5618561 |
Preparation of highly hydrated self-supporting hyaluronic acid containing films
This invention provides new gels in the form of highly hydrated self-supporting film, comprising one or more alkaline alginates, an alkaline earth alginate, a polyalcohol and a hyaluronic acid or a...
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5616343 |
Cross-linked amylose as a binder/disintegrant in tablets
The present invention is concerned with the manufacture of solid dosage units (pharmaceutical and others). More specifically, the invention is related to powders of cross-linked amylose, having a...
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5616340 |
Process for making a hard-candy based oral pharmaceutical lozenge containing an antacid
A hard-candy based lozenge containing an antacid is produced in a manner compatible with a continuous process method of manufacture. Sucrose solution, corn syrup, and a carbonate antacid are mixed,...
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5614487 |
Sustained release pharmaceutical composition
The present document discloses the formation of imine adducts, preferably between a primary amine of a biologically active polypeptide and a reactive aldehyde group of a physiologically acceptable...
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5614221 |
Method of preparing a drug delivery system comprising a drug and a gel using a syringe
This invention relates to a drug delivery system comprising one or more pharmacologically active substances, aggregating agent and a polysaccharide matrix having pseudoplastic properties, to a...
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5609883 |
Compressed tablet transitory lubricant system
A method is provided for making fast dissolving storage stable tablets by compression on standard high speed tablet production machinery wherein the formulation contains a carbohydrate having a...
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5607695 |
Process for the manufacture of porous cellulose matrices
A process for the manufacture of porous cellulose particles, which have regular shape, and a capacity of sorbing 1.5-9 times of their own weight of water, a tap bulk density of less than 0.85 g/ml...
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5603956 |
Cross-linked enzymatically controlled drug release
The present application is concerned with a solid slow release pharmaceutical dosage unit. More specifically, the invention is directed to a tablet form prepared by direct compression of...
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5601842 |
Sustained release drug formulation containing a tramadol salt
A drug formulation of tramadol or a tramadol salt in orally administrable tablet form containing at least one pharmaceutically acceptable matrixing agent is disclosed from which a non-moisture...
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5599557 |
Stable hydrated cephalosporin dry powder for oral suspension formulation
A dry hydrated cephalosporin, e.g. ceftibuten having about 7 to 14% by weight of water, powder formulation, pharmaceutical compositions in the form of an oral suspension dosage form and a method of...
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5599555 |
Encapsulated cometic compositions
This invention relates to polymeric liquid crystals prepared from a polysaccharide and a solvent, preferably water, which are used to deliver nutrients, perfumes, flavors, drugs and other...
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5599916 |
Chitosan salts having improved absorbent properties and process for the preparation thereof
Disclosed is a method for producing a water-swellable, water-insoluble chitosan salt having improved absorption properties. The method involves forming a mixture of a chitosan, water, an acid, and,...
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5597897 |
Pharmaceutical formulations of osteogenic proteins
A composition comprising a pharmaceutically acceptable admixture of an osteogenic protein; a polymer matrix component selected from the group consisting of poly(lactic acid), poly(glycolic acid),...
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5595749 |
Insecticide composition and process for making same
An insecticide spray is provided with a water insoluble organophosphate ester (tetrachlorvinphos) that is emulsified in an aqueous carrier and may be delivered via a pump or aerosol to kill fleas...
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5595760 |
Sustained release of peptides from pharmaceutical compositions
The invention features a method of administering a peptide to a patient and delivering the peptide continuously over an extended period of time of at least three days by obtaining a solid...
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5595761 |
Particulate support matrix for making a rapidly dissolving tablet
The present invention comprises a particulate support matrix for making a solid tablet form, and method for making such, which disintegrates or dissolves in a matter of just a few seconds once...
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5591709 |
Compositions and methods for treating wounds
The present invention relates to wound treatment formulations and methods for treating wounds utilizing these formulations. The formulations according to the present invention are useful for...
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5591455 |
Wet powder film-forming compositions
An improved wet powder, edible, film-forming composition for use in coating tablets and capsules consists essentially of powdered pigment particles, a film-forming, water soluble or...
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5587179 |
Pharmaceutical formulation in the form of an effervescent and/or disintegrating tablet or of instant granulate, and process for their preparation
The pharmaceutical formulation in the form of an effervescent and/or disintegrating tablet or of instant granules contains at least one active ingredient having an irritating taste and at least one...
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5585093 |
Cosmetic deodorant compositions containing encapsulated bicarbonate and liquid fragrance ingredients
This invention provides deodorant and antiperspirant-deodorant cosmetic stick and roll-on products with an organic matrix having a dispersed particle phase of an encapsulated bicarbonate salt...
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5585118 |
Choline in the treatment of bipolar disorder
The present invention is directed to methods in which a lithium source and a choline source act synergistically to reduce or eliminate the symptoms associated with bipolar disorder.
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5578322 |
Quick release coated preparation
A coated preparation prepared by coating drug particles having a disagreeable taste with a mixture comprising a hydrophobic substance with a melting point of 45° to 90° C. and a surfactant with a...
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