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7579021 |
Drug delivery systems based on degradable cationic siloxanyl macromonomers
Matrix controlled diffusion drug delivery systems based on one or more silicon-containing monomers of the general formula:
wherein L, X − , n, R1, R2, R3, R4, R5, R6, R7 and V are as set...
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7544673 |
Coating compositions for bioactive agents
A coating composition and related method for use in applying a bioactive agent to a surface in a manner that will permit the bioactive agent to be released from the coating in vivo. The composition...
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7531604 |
Phospholipid derivative
A phospholipid derivative, utilizable for modification of liposomes and the like, which is a copolymer containing, as essential component units, a component unit A represented by the formula (1), a...
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7482381 |
Artificial muscle hydrogel blends reversibly electroactuated near neutral pH, implantable actuating devices, and methods using the same
A novel artificial muscle material and miniature valves and micropumps made therefrom are provided. The artificial muscle material bends reversibly when electroactuated by applying low voltage, in...
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7442369 |
Compositions of minoxidil
Novel compositions comprising minoxidil, a thickening agent, and a pharmaceutically acceptable solvent are presented. Also presented is a process for making a novel gel composition comprising...
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7431943 |
Controlled release and taste masking oral pharmaceutical compositions
Controlled release and taste masking compositions containing one or more active principles inglobated in a three-component matrix structure, i.e. a structure formed by successive amphiphilic,...
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7425322 |
Responsive biomedical composites
A responsive polymeric system including a responsive polymeric component capable of undergoing a transition that results in a sharp increase in viscosity in response to a triggering effected at a...
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7419685 |
Process for producing solid dosage forms
Solid dosage forms containing at least one polymer binder, at least one active ingredient and, where appropriate, conventional additives, wherein a physiologically tolerated, water-swellable graft...
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7417021 |
Biologically active conjugate of a biopolymer and therapeutic agent
A biologically active conjugate is disclosed comprising a biopolymer and a therapeutic agent joined by a disulfide bond. The conjugate, when formulated in a pharmaceutical composition with a...
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7413752 |
Composite hydrogel drug delivery systems
Compositions and methods are provided to control the release of relatively low molecular weight therapeutic species through hydrogels by first dispersing or dissolving such therapeutic species...
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7399739 |
Vertebral augmentation composition and method
A flowable vertebral augmentation composition for the treatment and repair of a vertebral body defect, e.g., an osteoporotic condition, contains biocompatible, optionally osteoconductive, support...
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7393544 |
Dispersion for pulmonary delivery of a bioactive agent
Stabilized dispersions are provided for the delivery of a bioactive agent. The dispersions preferably comprise a plurality of perforated microstructures dispersed in a suspension medium that...
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7378109 |
Pharmaceutical composition for improving palatability of drugs and process for preparation thereof
The present invention discloses compositions, comprising a lipid-polymer matrix to mask the bitter or unpleasant taste of the medicament. The lipid or a blend of lipids, are used in combination...
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7357943 |
Pharmaceutical preparation in the form of a suspension comprising an acid-labile active ingredient
The present invention relates to the field of pharmaceutical technology and describes a novel pharmaceutical preparation in the form of a suspension comprising an acid-labile active ingredient, in...
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7326425 |
Pharmaceutical formulation composed of a polymer blend and an active compound for time-controlled release
A formulation containing a biologically active compound having a structure with hydrogen bonding sites blended with a first polymer having a structure with complementary hydrogen bonding sites and...
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7318937 |
Liquid coating compositions
Liquid coating compositions are provided that comprise siloxane containing polymer, volatile polydimethylsiloxane, and aliphatic hydrocarbon. The liquid coating compositions preferably comprise...
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7297673 |
Thickener for high-pH aqueous systems
An aqueous composition having a pH of at least 10, and comprising from 0.1% to 5% of at least one crosslinked copolymer comprising from 2.5% to 65% (meth)acrylic acid residues, from 10% to 80% C 2...
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7294347 |
Coating compositions for bitterness inhibition
The present invention discloses coating compositions with taste masking property, comprising a blend of pH sensitive polymers and optionally a pH independent polymer or a blend of the pH sensitive...
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7282218 |
pH sensitive polymer for inhibiting transformation in drugs
The present invention discloses a substantially amorphous pharmaceutical composition comprising a drug that can exist in a variety of polymorphic forms and a pH sensitive polymer, which inhibits...
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7267828 |
Light stabilized antimicrobial materials
Methods of enhancing the photostabilizing of silver in medical materials are described. More particularly, the methods increase the photostabilization of silver in certain materials comprising...
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7238761 |
Multifunctional biocompatible hydrophilic gel and the method of gel manufacture
Multifunctional biocompatible hydrophilic gel contains, in % (w/w), acrylamide—1.95-8.0, methacrylamide—0.54-3.0, 2-hydroxyethyl methacrylate—0.003-0.4,...
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7229647 |
Chlorine dioxide gel and associated methods
A method of making a composition having the property of being able to store chlorine dioxide includes mixing an aqueous chlorine dioxide solution with a superabsorbent, water-soluble polymer that...
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7204997 |
Responsive microgel and methods related thereto
A responsive microgel is provided which responds volumetrically and reversibly to a change in one or more aqueous conditions selected from the group consisting of (temperature, pH, and ionic...
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7192693 |
Methods for photopatterning hydrogels
In one aspect, the invention provides methods for forming a photopatterned hydrogel. In some embodiments, the methods comprise the step of exposing a solution comprising a monomer, a crosslinking...
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7189414 |
Controlled release oral drug delivery system
The invention relates to synchronous drug delivery composition comprising a polymeric matrix which comprises hydrogel blended with a hydrophobic polymer, so as to form an erodible matrix, a drug,...
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7169411 |
Composition for delivery of biological agents and methods for the preparation thereof
A composition for facilitating delivery of biological agents, comprising a therapeutic or diagnostic agent and a supramolecular complex, the latter comprising (i) a block copolymer, having at least...
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7169318 |
Imbibed organic liquids, especially halogenated organics
Solid composition has an organic spill absorbing material in which is absorbed certain of a liquid organic compound or composition. The organic spill absorbing material can be water insoluble,...
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7166304 |
Degradable heterobifunctional poly(ethylene glycol) acrylates
A heterobifunctional poly(ethylene glycol) is provided having a hydrolytically degradable linkage, a first terminus comprising an acrylate group, and a second terminus comprising a target such as a...
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7160553 |
Matrix for oxygen delivery to compromised tissues
The present invention comprises methods and compositions for delivery devices. More particularly, the present invention comprises methods and compositions for devices comprising a matrix comprising...
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7157414 |
Methods of reducing irritation in personal care compositions
Provided are methods of reducing the irritation associated with a personal care composition comprising an anionic surfactant, the methods comprising combining a hydrophobically-modified material...
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7138132 |
Hydrogel entrapping therapeutic agent and stent with coating comprising this
A hydrogel forming system which comprises a hydrophobic macromer with unsaturated group terminated ends and a hydrophilic polymer which is a polysaccharide containing hydroxy groups which are...
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7132452 |
Topical formulation having effects on alleviating pain/inflammation caused by herpes virus infection
The present invention provides a topical formulation containing NSAID, particularly diclofenac. The topical formulation is particularly useful for alleviating pain/inflammation associated with...
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7128927 |
Emulsions for in-situ delivery systems
The invention is provides a composition for sustained delivery of a biologically active agent comprising a biologically active mixture and a controlled release formulation. The composition protects...
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7125570 |
Antibacterial composition
An antibacterial composition is provided which comprises a base, an antibacterial agent consisting of a silver-supporting inorganic compound and a water-soluble salt of a nitrogen atom-containing...
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7119059 |
Mild and effective cleansing compositions
A mild cleansing composition is disclosed. The composition includes a from about 3.5 percent to about 8.5 percent of an anionic surfactant; from about 0.1 percent to about 3 percent of a...
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7118761 |
Method for producing a silver-containing wound care device
Wound care devices having a topically applied silver-based antimicrobial finish are provided. The finish comprises at least one silver ion-containing compound and at least one binder compound. The...
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7101840 |
Polymeric drug formulations
A method of forming a polymeric drug formulation in which a water-soluble drug is blended with a water-insoluble tissue-compatible polymer that is miscible in the solid phase with the drug, and...
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7098180 |
Mild and effective cleansing compositions
A mild cleansing composition is disclosed. The composition includes a from about 4 percent to about 8.5 percent of an anionic surfactant; from about 1 percent to about 30 percent of an amphoteric...
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7097855 |
Transdermal thermal polymerization
An invention for polymerizing or crosslinking a prepolymer using a water soluble, thermal polymerization initiator is disclosed. The prepolymer mixed with the initiator is injected or placed into...
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7090866 |
Opioid agonist in a fast dispersing dosage form
This invention relates to a pharmaceutical composition for oral administration comprising a carrier and, as active ingredient, an opioid (μ receptor) agonist, such as fentanyl, or a salt thereof,...
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7084104 |
Mild and effective cleansing compositions
A mild cleansing composition is disclosed. The composition includes a from about 1 percent to about 8 percent of an anionic surfactant; and from about 0.1 percent to about 3 percent of a...
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7083806 |
Wound gels
The present invention relates to hydrogels, in particular gels for use on wounds. The invention provides a gel which is better able to maintain viscosity and gel integrity when exposed to wound...
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7070808 |
Adhesive mixture for transdermal delivery of highly plasticizing drugs
Transdermal drug delivery patches and methods of their production are described. The patches can be made such that the accommodate highly plasticizing drugs such as selegiline and/or the use of...
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7060296 |
Hydrolysable hydrogels for controlled release
The present invention relates to a biodegradable hydrogel comprising bonds which are hydrolyzable under physiological conditions. More particularly, the hydrogel consists of two interpenetrating...
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7056533 |
Medicament incorporation matrix
A coating composition, in both its uncrosslinked and crosslinked forms, for use in delivering a medicament from the surface of a medical device positioned in vivo. Once crosslinked, the coating...
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7056532 |
Compositions for delivery of biological agents and methods for the preparation thereof
A composition for facilitating delivery of biological agents, comprising a supramolecular complex including as constituents a block copolymer, having at least one nonionic, water soluble segment...
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7056527 |
Patches containing buprenorphine hydrochloride
A patch comprising an adhesive layer formed on one surface of a flexible support, wherein said adhesive layer containing a drug, an absorption enhancer and an adhesive comprising;
(i) said drug is...
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7052719 |
Matrices formed of polymer and hydrophobic compounds for use in drug delivery
A lipid or other hydrophobic or amphiphilic compound (collectively referred to herein as “hydrophobic compounds”) is integrated into a polymeric matrix for drug delivery to alter drug release...
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7025990 |
Methods for forming regional tissue adherent barriers and drug delivery systems
Methods are provided for forming hydrogel barriers in situ that adhere to tissue and prevent the formation of post-surgical adhesions or deliver drugs or other therapeutic agents to a body cavity....
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7018656 |
Antimycotic gel with high active substance release
A pharmaceutical preparation comprising a hydrophilic gel-forming agent, water and a compound of the formula I
is suitable for the treatment and prophylaxis of dermatomycoses.
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