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6207193 Transdermal drug delivery system  
There is disclosed a transdermal drug delivery system wherein a drug or therapeutic agent is encapsulated in a water soluble carbohydrate. The carbohydrate-encapsulated drug or therapeutic agent,...
6200600 Controlled delay release device  
Novel devices for the controlled release of active materials especially pharmaceuticals comprise a capsule formed from two separable pieces at least part of the capsule walls is water permeable....
6200589 Biological implants of semipermeable amphiphilic membranes  
An implantable biological device including a semipermeable membrane formed into a geometric shape capable of encapsulating biological cells and capable of immunoisolating the biological cells upon...
6194000 Analgesic immediate and controlled release pharmaceutical composition  
Disclosed is a method for the therapeutic treatment of pain related to wind up in a human or animal. The method of the invention is practiced by administering to the subject an effective amount of...
6190699 Method of incorporating proteins or peptides into a matrix and administration thereof through mucosa  
The present invention describes a surprising new and effective pharmaceutical composition comprising microparticles and a pharmaceutically acceptable carrier. In particular, the present invention...
6187343 Proceeding for the preparation of the prolonged action granule compound containing 4-nitro-2-phenoxymethanesulfonanilide  
The invention includes a compound formulated by means of an association of sustained liberation in granules that maintains the therapeutic action of 4-nitro-2-phenoxymethanesulfonanilide and with a...
6174919 Cyanoacrylate compositions with vinyl terminated ester groups  
An adhesive composition includes compounds having the following formula: ##STR1## wherein R 1 is alkyl, alkoxy alkyl, anhydride, ether, ester, or amide, and R 2 and R 3 are hydrogen, alkyl,...
6174535 Hydrated honey gel polymeric compositions and process for preparing same  
This invention deals with the delivery of liquid polysaccharides to a cosmetic and toiletry products. A unique formulation is prepared which permits the incorporation of honey into such cosmetic...
6165509 Pegylated drug complexed with bioadhesive polymer suitable for drug delivery and methods relating thereto  
PEGylated drugs complexed with bioadhesive polymers, wherein the PEGylated drugs comprise a polyethylene glycol covalently bonded to the drugs are disclosed. The PEGylated drug/bioadhesive polyner...
6162467 Sustained release compositions and a method of preparing pharmaceutical compositions  
A process for the manufacture of particles comprises mechanically working a mixture of a drug and a hydrophobic and/or hydrophilic fusible carrier in a high speed mixture so as to form...
6162456 Adhesive transdermal drug delivery matrix of a physical blend of hydrophilic and hydrophobic polymers  
Adhesive matrixes for use in administering drugs transdermally in which the adhesive component is a homogenous physical blend of a hydrophilic polymer adhesive and a hydrophobic polymer adhesive....
6162420 Use of glyceryl triacetate for treating onychomycoses  
6156346 Urease-responsive delivery systems for diagnostic and therapeutic applications  
A delivery system that releases a diagnostic marker or therapeutic agent in a manner sensitive to the concentration of urease in a physiological compartment, particularly the gastrointestinal...
6156345 Crosslinkable macromers bearing initiator groups  
A crosslinkable macromer system that includes two or more polymer-pendent polymerizable groups and one or more polymer-pendent initiator groups. The polymerizable groups and the initiator group(s)...
6146771 Process for modifying surfaces using the reaction product of a water-insoluble polymer and a polyalkylene imine  
A process for modifying a surface of an article that includes treating a surface with a solution that includes an organic solvent, and the reaction product of a substantially water insoluble...
6143278 Topical application of opioid analgesic drugs such as morphine  
The invention is directed to methods and pharmaceutical compositions for the topical administration of opioid analgesic drugs such as morphine. In particular, the invention relates to topical...
6139861 Intraoral topical anti-inflammatory treatment for relief of migraine, tension-type headache, post-traumatic headache facial pain, and cervical-muscle spasm  
An anti-inflammatory, either a NSAID or glucocorticoid steroid in the form of an ointment, cream, lotion, gel, powder, paste, film, tape or adhesive bandage, provided with appropriate vehicle to...
6132749 Sustained release pheromone-containing preparations  
A sustained release pheromone-containing preparation is obtained by incorporating a sex pheromone having a heat of evaporation ranging from 21,000 to 27,000 cal/mole and a parameter, as a measure...
6123953 Cosmetic, dermopharmaceutical or veterinary compositions for disinfecting human or animal skin  
6103264 Process for preparing a controlled release composition  
A process for preparing a controlled release composition with a controlled release matrix and containing a pharmaceutically active ingredient, which comprises granulating the active ingredient with...
6103262 Modified-release metronidazole compositions and methods for making and using same  
Pharmaceutical compositions having a modified release profile for once daily dosing of metronidazole, methods for making the pharmaceutical compositions, and methods for treating a microbial...
6090368 Pharmaceutical compositions for intranasal spray administration of ketorolac tromethamine  
A pharmaceutical composition of a water soluble drug admixed with an aqueous bioadhesive cellulosic polymer containing microcrystalline particles. When sprayed (via a conventional spray device)...
6083534 Pharmaceutical compositions for controlled release of soluble receptors  
A controlled release pharmaceutical composition includes a biocompatible polymeric material, preferably polyethylene-vinyl acetate or poly(lactic-glucolic acid), having incorporated therein a...
6083518 Composition comprising an active agent dissolved in a glass-forming carrier and a process for the preparation thereof  
A biologically active composition comprising a solution of an active agent dissolved in a glass-forming carrier, which carrier comprises a glass-forming substance (A) containing a plasticizer (B),...
6071528 Adhesive antimicrobial and/or reparative dentin stimulating dental compositions and methods for forming and using such compositions  
Adhesive antimicrobial dental compositions and methods for forming and using compositions are disclosed. The compositions are primarily useful as pulp caps and dentin liners. The composition...
6066339 Oral morphine multiparticulate formulation  
An oral morphine multiparticulate formulation for once-daily administration to a patient, comprising sustained release particles each having a core containing water soluble morphine and an osmotic...
6036970 Rodenticidal foams  
The present invention relates to rodenticidal foams based on hydrophilic polymers, of the following composition: a) rodenticidal active compound, b) hydrophilic polymers having an average...
6037374 Composition and method for the control of parasitic mites in honey bees  
Gel compositions of formic acid and a gelling agent such as fumed silica or polyacrylic acid have been prepared for controlling parasitic mites of honey bees. The gels provide slow-release...
6030634 Polymer gel composition and uses therefor  
The present invention general relates to thermally responsive polymer gel compositions that have enhanced temperature-dependent shrinking rates, increased strength, and improved pliability over...
6024974 Composition and methods for transdermal delivery of acid labile drugs  
A transdermal composition and related method are described. Specifically, the transdermal composition is substantially free of gestodene or substantially free of isopropyl myristate and...
6022554 Polymeric microporous film coated subcutaneous implant  
This invention relates to coating formulations for coating sustained-release drug implants. The coating formulations are capable of formulations are capable of forming a porous film coat over a...
6013276 Transdermal matrix system  
A novel transdermal matrix system for the percutaneous delivery of a hormone, including a carrier and an adhesive matrix, is disclosed. The matrix includes (a) 39-61 parts by weight of an...
6004583 Protein-containing polymer composition for oral administration  
A therapeutic-containing composition adapted for the oral administration of a biologically active material which comprises a water insoluble but water swellable polymer chemically modified with an...
5993790 Nail evulsion compositions and method for evulsing nails and treating nail and nail bed infections  
Disclosed is a composition comprising a water based nail lacquer and urea, which is useful in the partial or complete evulsion of the nails, and in the treatment of fungal, yeast and bacterial...
5985326 Method of producing a solid dispersion of a poorly water soluble drug  
Solid dispersions of poorly soluble drugs, such as (6R,12aR)-2,3,6,7,12,12a-hexahydro-2-methyl-6-(3,4-methylene dioxyphenyl)-p yrazino[2',1':6,1]pyrido[3,4-b]indole-1,4-dione and...
5980951 Oral coated active drugs  
An oral drug dosage unit, for administration to a patient, having active drug, and an effective diameter and surface composition sufficient for the unit to be transported from the stomach into the...
5976577 Process for preparing fast dispersing solid oral dosage form  
Process is provided for preparing an oral solid rapidly disintegrating freeze-dried dosage form of a pharmaceutically active substance having an unacceptable taste, wherein prior to freeze drying,...
5972373 Taste masking pharmaceutical composition for oral administration  
[Object] To provide a composition for oral administration which is excellent in masking a taste of an unpleasant tasting drug and in bioavailability. [Constitution] A composition for oral...
5968555 Fine particulate cross-linked type N-vinylamide resin  
A fine particulate cross-linked N-vinylamide resin having an average particle size of not more than 10 μm comprising a compound (I) and a compound (II) cross-linked by a cross-linking agent:...
5965163 Substained release compositions and a method of preparing pharmaceutical compositions  
A process for the manufacture of particles comprises mechanically working a mixture of a drug and a hydrophobic and/or hydrophilic fusible carrier in a high speed mixture so as to form...
5965161 Extruded multi-particulates  
A unit dose sustained-release oral dosage form containing a plurality of melt-extruded particles, each consisting essentially of a therapeutically active agent, one or more retardants, and an...
5962520 Hydrolytically unstable, biocompatible polymer  
A hydrolytically unstable, biocompatible polymer capable of carrying and releasing a pharmaceutical compound when introduced into physiological media. In a preferred embodiment, the polymer...
5948438 Pharmaceutical formulations having improved disintegration and/or absorptivity  
An oral solid dosage form, comprising a compressed tablet including an excipient comprising (a) microcrystalline cellulose; and (b) a compressibility augmenting agent which (I) physically restricts...
5948420 Pharmaceutical and cosmetic compositions and their production  
Substantially clear gelled compositions suitable for use in cosmetics or pharmaceutical compositions and containing cationic polymer are formed by solvating a reverse phase emulsion of water...
5945113 Pesticidal paste compositions  
A readily, water-dispersible pesticide formulation in the form of a thick paste containing 1 to 80% by weight of the pesticide, 0.30 to 2.0% by weight of a micropore-generating agent and 30 to 50%...
5939208 Method for creation of biomimetic surfaces  
In the present invention method, the surface of articles made of acrylic polymers and methacrylic polymers are converted into thin biomimetic layers by using the process involving at least the...
5935594 Process and device for treating and healing a tissue deficiency  
An improved method or process and device for treating and healing a bone void is disclosed, and in particular a method employing a surfactant for efficiently incorporating a biologically active...
5925368 Protection of wooden objects in direct contact with soil from pest invasion  
A method and device are disclosed which preventing the decay and deterioration of wooden objects caused by pests by using a controlled release device. This controlled release device utilizes...
5925379 Interpenetrating polymer networks for sequestration of bile acids  
The present invention relates to a method for removing bile salts from a patient, comprising the step of administering to the patient a therapeutically effective amount of a polymer network...
5919442 Hyper comb-branched polymer conjugates  
A novel class of hyper comb-branched polymers conjugated with carried materials are disclosed.