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6479076 |
Nicotine delivery compositions
A composition containing nicotine and an uncrosslinked, water-insoluble vinylpyrrolidone copolymer is applied on the skin of patients in the form of a gel, ointment, solution, suspension or film...
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6471993 |
Three-dimensional polymer matrices
Matrices that include a macrostructure having a semi-solid network and voids, and a microstructure having voids, in which the microstructure is located within the semi-solid network are disclosed....
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RE37890 |
Controlled delivery compositions and processes for treating organisms in a column of water or on land
Controlled release compositions of matter are disclosed comprising complexes for treating a population of one or more aquatic organisms in a column of water. The complexes comprise at least one...
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6465001 |
Treating medical conditions by polymerizing macromers to form polymeric materials
Water soluble macromers are modified by addition of free radical polymerizable groups, such as those containing a carbon-carbon double or triple bond, which can be polymerized under mild conditions...
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6464999 |
Bioadhesive medical devices
Disclosed herein are bioadhesive medical devices formed in whole or in part of a cohesive bioadhesive copolymer of a carboxyl functional monomer and a hydrophobic functional monomer.
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6462093 |
Method for converting sparingly water-soluble medical substance to amorphous state
A process for producing a solid dispersion of a sparingly water-soluble medical substance which comprises subjecting the sparingly water-soluble medical substance, an amorphous state-inducing agent...
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6458763 |
Bone sialoprotein-based compositions for enhancing connective tissue repair
The present invention is directed to bioactive compositions that induce the repair of damaged or diseased connective tissues upon contact of the damaged or diseased tissues with the composition in...
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6455070 |
Composition for treating symptoms of influenza
A composition for relief of symptoms of colds and influenza, containing, by weight, about 80-88% olive leaf extract powder containing oleuropein, about 5-10% neem leaf powder and up to about 8% of...
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6447803 |
Thickener-rheology modifier system for personal care compositions
A selected thickener-rheology modifier system comprising the combination of a hydrophobically, modified alkali-soluble thickener and a polysaccharide hydrocolloid or gum or polyalkylene glycol,...
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6436440 |
Use of N-vinyllactam-or-N-vinylamine-containing copolymers as matrix for producing solid pharmaceutical and cosmetic presentations
The use of copolymers comprising a) 50 to 99% by weight of at least one N-vinyllactam or N-vinylamine selected from the group consisting of N-vinylpyrrolidone, N-vinylpiperidone,...
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6428813 |
Gastrointestinal mucosa-adherent pharmaceutical composition
In order to provide a composition having a long gastroduodenal residence time and exhibiting an improved efficacy, is provided a gastrointestinal mucosa-adherent composition comprising an active...
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6423332 |
Method and composition for deforming soft tissues
The present invention provides a composition and method for augmenting soft tissue, which composition includes a continuous phase that is a solid at temperatures less than about 10° C. or greater...
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6417237 |
Macromolecular drug complexes and compositions containing the same
Macromolecular drug complexes containing a drug, like human growth hormone, and a polymer having a plurality of acid moieties, like carboxyl moieties or phosphonic acid moieties, and compositions...
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6416769 |
Cosmetic compositions comprising exfoliating enzymes and uses thereof
Cosmetic compositions for topical use that comprise an exfoliating enzyme for use in removal of at least a portion of the dead skin cells from the outer layer of skin, in conjunction with one or...
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6410045 |
Drug delivery system for antiglaucomatous medication
A drug delivery system for antiglaucomatous medications utilizing a polymeric hydrogel which can absorb an ophthalmic medication which can then be transferred into the ocular fluid of the eye.
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6399086 |
Pharmaceutical preparations for the controlled release of beta-lactam antibiotics
The present invention relates to a pharmaceutical controlled-release oral drug delivery system comprising as active ingredient at least one β-lactam antibiotic agent, having a specific absorption...
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6399092 |
Anhydrous, hydrophilic absorbent wound dressing (tube) with antimicrobials or other pharmaceutically active agents
An anhydrous, hydrophilic wound dressing containing a superabsorbent polymer and an antimicrobial agent. Its anhydrous nature allows it, when applied to a wound site, to absorb wound fluid and...
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6395749 |
Carboxamide compounds, methods, and compositions for inhibiting PARP activity
The present invention provides carboxamine compounds, methods and compositions for inhibiting PARP activity.
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6395289 |
Hydrophilic polymer blends used to prevent cow skin infections
The invention discloses a mammalian teat dip for controlling mastitis, a method for preparing the composition and a method of treatment of mammals. The composition contains a film-forming polymer...
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6391294 |
In situ formation of polymeric material
A pharmaceutically acceptable bio-adhesive coating, film or gel is formed in situ at a body surface by the reaction of (i) an anionic polymer or tripolyphosphate and (ii) a cationic polymer in the...
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6391338 |
System for rendering substantially non-dissoluble bio-affecting agents bio-available
The present invention is a method of preparing a system for delivering a bio-affecting agent and the composition prepared thereby. The invention includes forming a molecular dispersion of the...
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6387977 |
Redox and photoinitiator systems for priming for improved adherence of gels to substrates
An impoved barrier or drug delivery system which is highly adherent to the surface to which it is applied is disclosed, along with methods for making the barrier. In the preferred embodiment,...
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6372248 |
Dehydrated hydrogels
A dehydrated hydrogel incorporating a plasticiser and fibers which have provided cations for cross-linking the dehydrated hydrogel.
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6368631 |
Fine grain carriers and medicinal composition prepared with the use of the same
The present invention is directed to particulate carriers useful as drug carriers in a drug delivery system (DDS) and to pharmaceutical compositions making use of such carriers. The invention is...
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6344212 |
Method of providing sustained analgesia with buprenorphine
A method of effectively treating pain in humans is achieved by administering buprenorphinein accordance with first order kinetics over an initial three-day dosing interval, such that a maximum...
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6342241 |
Medical composition of hydroxy acid-based oligomer
A medical composition is here disclosed which comprises a hydroxy acid-based oligomer (A) and a drug (B), wherein the hydroxy acid-based oligomer (A) is an oligomer in which the carboxylic...
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6340464 |
Adjuvants for vaccines
Vaccine adjuvants comprising a liquid medium contain polymers with anionic constitutive repeating units and hydrophobic constitutive repeating units. Advantageously, the adjuvants are aqueous...
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6322817 |
Formulations of paclitaxel, its derivatives or its analogs entrapped into nanoparticles of polymeric micelles, process for preparing same and the use thereof
This invention relates to pharmaceutical formulations of paclitaxel, its derivatives or analogs entrapped into nanoparticles of co-polymeric micelles, a process for preparing the same and the use...
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6322815 |
Multipart drug delivery system
Polymeric drug conjugates in controlled release matrices are provided which allow sustained concentrations of therapeutic agents within a treated area for a prolonged period. The polymeric drug...
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6316021 |
Extensible mask including an adhesive matrix that can be stretched at least in the wet state
The invention relates to a mask for the face or the body, which mask comprises a backing sheet coated on one of its faces with an adhesive matrix containing a permanent adhesive that adheres both...
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6316022 |
Transdermal compositions containing low molecular weight drugs which are liquid at room temperatures
A transdermal composition is disclosed which contains a blend of one or more polymers, one or more drugs, at least one of which has a low molecular weight and is liquid at or about room...
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6312715 |
Adhesive microsphere drug delivery composition
Transdermal drug delivery compositions comprising pressure sensitive adhesive microspheres that contain a softening agent and/or a drug. Typically the microspheres contain at least 10 wt-% of a...
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6312726 |
Gastric remaining preparation, swollen molding, and production process
A gastric remaining preparation having a configuration entirely different from that of the conventional ones. It comprises a swollen molding having a mesh-like cross-section and an apparent density...
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6309665 |
Composition with sustained release of active principle, capable of forming a microemulsion
The invention concerns a composition comprising a microemulsion forming system by contact with a hydrophilic phase brought, after ingestion, by the physiological fluid, said microemulsion forming...
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6306789 |
Mucoadhesive granules of carbomer suitable for oral administration of drugs
Mucoadhesive granules comprising a) carbomer and/or a salt thereof; and b) an inert filler. The granules preferably further comprise a pharmaceutically active agent suitable for sustained...
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6306422 |
Compositions and devices for controlled release of active ingredients
A method for the controlled release of a biologically active agent wherein the agent is released from a hydrophobic, pH-sensitive polymer matrix is disclosed and claimed. In one embodiment, the...
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6306835 |
Biocidal chitosan derivatives
3-trimethylammonium-2-hydroxypropyl-N-chitosan (CHI-Q188) and related chitosan derivatives exhibit antimicrobial activity at concentrations as low as 10-20 μg/mL, an order of magnitude lower than...
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6299899 |
Extremely flexible plaster acting dermally or transdermally, and method for producing same
A process for the production of an extremely flexible patch having a dermal or transdermal action and having an adhesive matrix layer which comprises the active compound and is provided with a...
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6280745 |
Methods and compositions for the delivery of pharmaceutical agents and/or the prevention of adhesions
The present invention provides a composition comprising one or more constitutive polymers and modifier polymers and/or hydrophilic co-surfactants useful for reducing adhesions or delivering...
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6271307 |
Use of polyalkylkene oxide-containing graft copolymers as solubilizers
The use of graft copolymers obtainable by grafting a) polyalkylene oxides with b) at least one monomer selected from the group of b 1 ) C 1 -C 30 -alkyl esters of monoethylenically...
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6267984 |
Skin permeation enhancer compositions comprising a monoglyceride and ethyl palmitate
Compositions, devices, and methods for transdermal administration of a drug are disclosed using a novel permeation enhancer mixture comprising a monoglyceride and ethyl palmitate. The...
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6264934 |
Low surface tension cosmetic copolymers
A vinylic copolymer comprising repeat units of A, B and C These copolymers have an acid content of 0.015 to 0.50 milliequivalents per gram of copolymer. Compositions that provide these copolymers...
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6254889 |
Solid dispersion dosage form of amorphous xanthine derivative and enteric-coating polymer
The present invention relates to a solid dispersion and a solid dispersion dosage form which comprise a xanthine derivative represented by the following formula (I) or a pharmacologically allowable...
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6248360 |
Complexes to improve oral absorption of poorly absorbable antibiotics
The present invention provides compositions and methods for increasing absorption of poorly absorbable antibiotics, particularly third generation cephalosporin antibiotics, in oral dosage solid...
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6238688 |
Method for repairing blood vessel system
The present invention generally relates to thermally responsive polymer gel compositions that have enhanced temperature-dependent shrinking rates, increased strength, and improved pliability over...
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6235314 |
Analgesic, anti-inflammatory and skeletal muscle relaxant compositions
Disclosed is a local skeletal muscle relaxant and a non-steroidal anti-inflammatory drug in a topical composition for topical application to a patient for relief of pain. More particularly and in...
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6235271 |
UV-protection formulation
The present invention provides, as a first aspect, a sun protection agent, which is especially suitable for use in pharmaceutical or cosmetic applications, comprising a) a micronized organic UV...
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6231872 |
Structured occlusive dressings
This invention relates to a composition containing a hydrophobic solvent, a network polymer and a flow control agent which is useful in healing wounds. The composition of this invention may be...
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6221382 |
Sheet pack
A sheet pack having a multi-layer moisture-permeable support including a hydrophobic layer and a hydrophilic layer, and a cosmetic substance, and a method for applying the sheet pack, including the...
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6217859 |
Microencapsulated genetically engineered microorganisms for clinical application
The present invention relates to a composition for oral administration to a patient for removal of undesired chemicals or amino acids caused by disease. The composition comprises an entrapped or...
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