|
Match
|
Document |
Document Title |
|
|
7615593 |
Bifunctional-modified hydrogels
Disclosed are hydrogels wherein a polymer matrix is modified to contain a bifunctional poly(alkylene glycol) molecule covalently bonded to the polymer matrix. The hydrogels can be cross-linked...
|
|
|
7592418 |
Biocompatible crosslinked polymers with visualization agents
Biocompatible crosslinked polymers, and methods for their preparation and use, are disclosed in which the biocompatible crosslinked polymers are formed from water soluble precursors having...
|
|
|
7588761 |
Human antibodies that bind human TNFα
Human antibodies, preferably recombinant human antibodies, that specifically bind to human tumor necrosis factor α (hTNFα) are disclosed. These antibodies have high affinity for hTNFα (e.g., K d...
|
|
|
7579019 |
Pharmaceutical carrier device suitable for delivery of pharmaceutical compounds to mucosal surfaces
The present invention relates to a pharmaceutical delivery device for application of a pharmaceutical to mucosal surfaces. The device comprises an adhesive layer and a non-adhesive backing layer,...
|
|
|
7550443 |
Process and systems for biocompatible surfaces
The invention provides methods and compositions for providing biocompatible surfaces to medical articles. In particular the invention provides biocompatible coatings with heparin activity that are...
|
|
|
7550155 |
Aqueous pharmaceutical compositions of 2,6-diisopropylphenol (propofol) and their uses
The present invention provides aqueous pharmaceutical compositions containing a lipophilic therapeutic agent. In particular, the invention provides aqueous pharmaceutical compositions containing...
|
|
|
RE40786 |
Vaccines against intracellular pathogens using antigens encapsulated within biodegradable-biocompatible microspheres
This invention relates to parenteral and mucosal vaccines against diseases caused by intercellular pathogens using antigens encapsulated within a biodegradable-biocompatible microspheres(matrix).
|
|
|
7544673 |
Coating compositions for bioactive agents
A coating composition and related method for use in applying a bioactive agent to a surface in a manner that will permit the bioactive agent to be released from the coating in vivo. The composition...
|
|
|
7544371 |
Drug delivery systems
Matrix controlled diffusion drug delivery systems based on one or more silicone-containing monomers of the general formula:
wherein x, y, m, m′, R, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 ,...
|
|
|
7541047 |
Method for production of shaped body for treating wounds in milk producing animals
Water-dispersible or water-soluble polymers, particularly those of the family of compounds comprising the poloxamers or the polyesters or amphiphilic agents (emulsifiers), and also lipophilic...
|
|
|
7534852 |
Polyanhydrides with therapeutically useful degradation products
An aromatic polyanhydride comprising a repeating unit having the structure
is disclosed, wherein Ar and R are selected so that the aromatic polyanhydride hydrolyzes to form a therapeutic...
|
|
|
7534449 |
Targeted and high density drug loaded polymeric materials
Polymeric delivery devices have been developed which combine high loading/high density of molecules to be delivered with the option of targeting. As used herein, “high density” refers to...
|
|
|
7531604 |
Phospholipid derivative
A phospholipid derivative, utilizable for modification of liposomes and the like, which is a copolymer containing, as essential component units, a component unit A represented by the formula (1), a...
|
|
|
7531191 |
Stimuli-responsive systems for controlled drug delivery
A method of delivering a therapeutic agent by providing a cross-linked polymer encapsulating the therapeutic agent to a site in a patient. The degradation rate of the cross-linked polymer is...
|
|
|
7517538 |
Solid supports functionalised with phosphorus dendrimers, method for preparing same and uses thereof
The present invention relates to solid supports functionalized with phosphorus-containing dendrimers, to a process for preparing them, to their use for preparing biochips and to the uses of these...
|
|
|
7485617 |
Osteoinductive materials
The present invention concerns improved osteoinductive materials comprising matrix materials and morphogenetic roteins, wherein depending on the subject matter the proteins may be dimeric or...
|
|
|
7485318 |
Biodegradable carrier and method for preparation thereof
A biodegradable carrier is produced for preservation and/or controlled delivery of biologically active agents where the biodegradable carrier is a silica xerogel which is made from water and silane...
|
|
|
7485317 |
Thermo-reversible polymer for intralumenal implant
An intralumenal implant material, which comprises, a polymer having a sol-gel transition temperature in an aqueous solution thereof, shows a substantial water-insolubility at a temperature higher...
|
|
|
7479254 |
Application using non-covalent bond between a cucurbituril derivative and a ligand
Provided are a kit including a first component that is a compound of formula (1) below bound to a first material and a second component that is a ligand bound to a second material, wherein each of...
|
|
|
7468394 |
Sterile pharmaceutical composition and process for a solution of propofol emulsion having microbial growth retardation
An oil-in-water propofol emulsion that contains soybean oil and egg lecithin, which provide a source of nutrition for microorganisms. Current products include additives to act as a microbial growth...
|
|
|
7462592 |
Compositions and methods for polynucleotide delivery
This invention relates compositions and methods for increasing the uptake of polynucleotides into cells. Specifically, the invention relates to vectors, targeting ligands, and polycationic agents....
|
|
|
7459172 |
Method of making a protein polymer and uses of the polymer
A polymer is prepared by self-assembly of a plurality of monomeric polypeptide units. The polymer tends to form a nanotube and is capable of encapsulating a particular drug molecule. Once...
|
|
|
7456213 |
PEG-poly(ortho ester) graft copolymers and pharmaceutical compositions
This invention relates to graft copolymer delivery vehicles comprising a polyethyleneglycol-poly(ortho ester), and to controlled release pharmaceutical compositions comprising the delivery vehicle...
|
|
|
7452525 |
Polyurethane dispersions based on polycarbonate polyols and suitable for use in personal care products
The invention relates to a process for preparing an aqueous polyurethane dispersion suitable for use in personal care products, wherein the polyurethane is based on one or more polycarbonate polyols.
|
|
|
7449136 |
Method and apparatus for producing composite particles using supercritical fluid as plasticizing and extracting agent
The present invention provides methods for producing composite particles using supercritical fluid as a plasticizing and extracting agent, composite particles formed in accordance with the methods...
|
|
|
7445799 |
Compositions for microbial and chemical protection
An antimicrobial and chemical deactivating composition for use in a liquid medium or for incorporation into a coating, structural plastic materials, thin microporous membranes, textiles and...
|
|
|
7445770 |
Polyurethane dispersions for use in personal care products
The invention relates to an aqueous polyurethane dispersion suitable for use in personal care products, the dispersed polyurethane comprising the reaction products of:
A) a prepolymer...
|
|
|
7442387 |
Pharmaceutical composition for controlled release of active substances and manufacturing method thereof
The present invention pertains to a sized product, which contains a drug, polyethylene oxide with a molecular weight of 2,000,000 or higher, and a specific size controlling agent for polyethylene...
|
|
|
7438928 |
Topical gel matrix
A topical gel matrix that can be used alone or combination with a medication entrapped therein. The gel matrix is dispersible in water. The gel may have the following composition: oil, water or...
|
|
|
7435790 |
Dihydroxypropyl cysteine peptide and agent containing this peptide
The invention relates to a S-(2,3-dihydroxypropyl)-cysteine peptide which has two long-chain fatty acids bonded in the form of esters at the dihydroxypropyl group, and which has the following...
|
|
|
7431943 |
Controlled release and taste masking oral pharmaceutical compositions
Controlled release and taste masking compositions containing one or more active principles inglobated in a three-component matrix structure, i.e. a structure formed by successive amphiphilic,...
|
|
|
7425528 |
Stabilization of granules
The present invention relates to granules comprising a core matrix and one or more coatings, wherein the core matrix comprises: An active compound, a synthetic polymer, where the amount of polymer...
|
|
|
7425322 |
Responsive biomedical composites
A responsive polymeric system including a responsive polymeric component capable of undergoing a transition that results in a sharp increase in viscosity in response to a triggering effected at a...
|
|
|
7419685 |
Process for producing solid dosage forms
Solid dosage forms containing at least one polymer binder, at least one active ingredient and, where appropriate, conventional additives, wherein a physiologically tolerated, water-swellable graft...
|
|
|
7417021 |
Biologically active conjugate of a biopolymer and therapeutic agent
A biologically active conjugate is disclosed comprising a biopolymer and a therapeutic agent joined by a disulfide bond. The conjugate, when formulated in a pharmaceutical composition with a...
|
|
|
7413753 |
Calcium phosphate delivery vehicles for osteoinductive proteins
A composition for delivery of osteogenic proteins is disclosed. The composition comprises an osteogenic protein, a calcium phosphate material as a carrier, and an effective amount of an...
|
|
|
7413752 |
Composite hydrogel drug delivery systems
Compositions and methods are provided to control the release of relatively low molecular weight therapeutic species through hydrogels by first dispersing or dissolving such therapeutic species...
|
|
|
7413750 |
Process for producing solid oral dosage forms with sustained release of active ingredient
The present invention relates to a process for producing solid oral dosage forms with sustained release of active ingredient, comprising at least one active ingredient, a preformulated mixture of...
|
|
|
7413747 |
Transdermal therapeutic system for treating Parkinsonism
A transdermal therapeutic system (TTS) comprises a silicone-based polymer adhesive system having distributed therein (−)-5,6,7,8-tetrahydro-6-[propyl-[2-(2-thienyl)ethyl]amino
]-1-naphthalenol...
|
|
|
7410947 |
Osteogenic devices and methods of use thereof for repair of endochondral bone and osteochondral defects
Disclosed herein are improved osteogenic devices and methods of use thereof for repair of bone and cartilage defects. The devices and methods promote accelerated formation of repair tissue with...
|
|
|
7407671 |
Temperature controlled solute delivery system
A system for delivering solute to a target location within a mammalian body, the system including a medical device, a thermosensitive cellulose gel structure over the medical device, and a...
|
|
|
7407670 |
Solid dispersions comprising two different polymer matrixes
Present invention provides solid dispersions comprising a poorly soluble bioactive compound dispersed in a polymer matrix characterized in that the polymer matrix comprises more than one polymer....
|
|
|
7405042 |
Method of extracting nucleic acid or protein using dendrimers and dendrimer-compositional substances
The present invention relates to a method of extracting nucleic acid or protein, in which multi-layer dendrimers are formed on the surface of fine particles, amino radicals for capturing nucleic...
|
|
|
7399483 |
Carrier with solid fibrinogen and solid thrombin
The present invention relates to a solid composition useful for tissue gluing, tissue sealing and haemostasis consisting essentially of a) a carrier which has at least one of the following physical...
|
|
|
7393547 |
Antimicrobial elastomer composition and method for making
A method for making an elastomeric material containing an antimicrobial composition such as a dispersion of silver oxide that is suitable for implantation within the body. The elastomer made in...
|
|
|
7384626 |
Functionalized dendritic polymers for the capture and neutralization of biological and chemical agents
The present invention describes compositions and methods for sorbing and/or destroying dangerous substances such as chemical and biological warfare agents. The present invention relates to...
|
|
|
7375096 |
Method of preparing a supramolecular complex containing a therapeutic agent and a multi-dimensional polymer network
A method of preparing a supramolecular complex containing at least one therapeutic agent and a multi-dimensional polymer network is described. A supramolecular complex prepared by a method of the...
|
|
|
7374774 |
Electroprocessed material made by simultaneously electroprocessing a natural protein polymer and two synthetic polymers
The invention is directed to novel compositions comprising an electroprocessed material and a substance, their formation and use. The electroprocessed material can, for example, be one or more...
|
|
|
7368125 |
Amphiphilic polymers for medical applications
The present invention is directed to medical devices or pharmaceutical compositions, each containing a synthetic, bioabsorbable, biocompatible polymer that is the reaction product of a polybasic...
|
|
|
7364752 |
Solid dispersion pharamaceutical formulations
A pharmaceutical composition is disclosed which comprises a solid dispersion of an HIV protease inhibitor in a water soluble carrier, such as PEG, having enhanced bioavailability and improved...
|