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6740643 |
Compositions and methods for drug delivery using amphiphile binding molecules
The present invention relates to the delivery of desired compounds (e.g., nucleic acids) into cells using noncovalent delivery systems which include complexing nucleic acids, amphipathic binding...
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6733790 |
Microcapsules and processes for making the same using various polymers and chitosans
A microcapsule having a mean diameter of from about 0.1 to about 5 mm, a membrane and a matrix containing at least one active principle wherein the microcapsule is the product of the process...
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6733786 |
Somatotropin composition with improved syringeability
The present invention relates to an improved somatotropin composition consisting of somatotropin having in vivo, at least one of lipid-soluble vitamins and at least one of pharmaceutically...
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6733785 |
Moisture-sensitive preparation of percutaneous absorption type
The invention relates to a percutaneous absorption preparation which comprises a supporting body, a medicine storage layer, a permeation controlling film, a layer of an adhesive and a release liner...
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6730318 |
Transdermal delivery devices containing polydiorganosiloxane polymers to regulate adhesive properties
The adhesive capability of matrix-type transdermal devices for the delivery of drugs, cosmetics, emollients and the like is altered by incorporating into the pressure-sensitive adhesive an...
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6730317 |
Patch, a kit constituted by a patch and a receptacle and a method
A patch comprising a matrix having adhesive properties in the dry state and containing at least one active substance, said matrix being attached via one face to a backing and being for application...
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6730311 |
Air fresheners comprising polyurethane/polyurea matrices for the delivery of fragrance agents
This invention relates to a picture frame assembly comprising (a) a frame panel comprising a sustained release fragrance material; (b) a picture panel comprising an adsorbent panel coated with a...
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6730323 |
Microclysmic gel for treatment of tissue trauma and burns
A therapeutic wound gel is provided which will enhance healing of the wound and reduce swelling and increase elasticity of the skin. Humatrix is bacteriostatic protectant with no bacteriocidal...
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6726932 |
Fatty acid-containing composition
The present invention provides a composition for enhancing the pharmacological activity of a water-soluble silicate polymer which comprises the water-soluble silicate polymer and a saturated fatty...
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6727280 |
Method for treating colorectal carcinoma using a taxane/tocopherol formulation
The present invention provides methods for administering a taxane composition for the treatment of cancer. In one aspect, the compositions are not diluted prior to administration. Some embodiments...
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6726931 |
Process for preparing oral sustained-release formulation of felodipine
The present invention relates to a process for producing an oral sustained-release pharmaceutical composition of felodipine. The process includes mixing together felodipine with at least an ionic...
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6723340 |
Optimal polymer mixtures for gastric retentive tablets
Unit dosage form tablets for the delivery of pharmaceuticals are formed of the pharmaceutical dispersed in a solid unitary matrix that is formed of a combination of poly(ethylene oxide) and...
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6723337 |
Transdermal drug delivery system for anti-inflammatory analgesic agent comprising diclofenac diethylammonium salt, and the manufacturing method thereof
The invention herein relates to a transdermal drug delivery systern for anti-Inflammatory analgesic. agent comprising diclofenac diethylammonium salt, wherein a backing film ( 1 ), a matrix layer (...
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6720007 |
Polymeric microspheres
The invention features core-shell microsphere compositions, hollow polymeric microspheres, and methods for making the microspheres. The microspheres are characterized as having a polymeric shell...
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6720073 |
Material enhancement to maintain high absorbent capacity under high loads following rigorous process conditions
An absorbent composite that can handle complex fluids and maintain high absorbent capacity under high loads even after the material has been subjected to rigorous processing conditions. The...
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6720006 |
Anti-microbial body care product
An anti-microbial body care product comprising in the part contacting the human or animal skin and/or mucosa and organic matrix containing homogeneously dispersed particles of a metallic silver...
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6713081 |
Ocular therapeutic agent delivery devices and methods for making and using such devices
Ocular implant devices for the delivery of a therapeutic agent to an eye in a controlled and sustained manner. Dual mode and single mode drug delivery devices are illustrated and described....
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6713509 |
Controlled release formulation for treating COPD
This invention relates to a controlled or sustained release formulation designed to deliver a PDE4 inhibitor for treating an inflammatory disease such as asthma or COPD and the like.
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6713087 |
Method of producing submicron particles of a labile agent and use thereof
The present invention relates to a sustained release composition comprising micron particles of labile agent and a method of preparing and using the sustained release composition. The invention...
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6706778 |
Process for the production of molded particles for microbial cell-immobilization
This invention provides a process for the production of molded particles for microbial cell-immobilization which is characterized in that: an aqueous liquid composition which comprises: (a) an...
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6703011 |
Application of film forming technology to fragrance control release systems; and resultant fragrance control release systems
Described is a fragrance control release system which is an emulsifier-free, single phase, nonporous, continuous, permeable polymeric film having a substantially uniform thickness of from about 1...
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6703035 |
Absorbable &egr -caprolactone copolymers
This invention deals with crystalline, nitrogen copolyester lubricant coating devices comprising sutures, wherein said lubricant comprises a triaxial copolyester chain with a central nitrogenous...
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6703039 |
Reversible gelling system for ocular drug delivery
The invention provides an ophthalmic aqueous composition for topical administration, comprising: (a) a block copolymer of propylene oxide and ethylene oxide in concentration sufficient to provide...
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6703045 |
Composition and method for maintaining blood glucose level
A composition useful for reducing serum glucose levels by an oral controlled release system and a method for treating diabetes in a human being by controlling the blood glucose level (BGL) and...
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6699500 |
Sustained-release preparation capable of releasing a physiologically active substance
Disclosed is a sustained-release preparation comprising 1) a polymer of lactic acid having a weight-average molecular weight of about 25,000 to about 60,000 and 2) a physiologically active...
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6699503 |
Hydrogel-forming sustained-release preparation
The invention provides a hydrogen-type sustained-release preparation comprising (1) at least one drug, (2) an additive which insures a penetration of water into the core of the preparation and (3)...
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6699498 |
Transdermal therapeutic systems having improved stability and their production
This invention provides for, inter alia, a transdermal therapeutic system comprising at least one therapeutically active substance, which is oxidizable by hydroperoxides, wherein the amount of...
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6699505 |
Method of increasing the efficacy of antibiotics by compexing with cyclodextrins
The present invention provides methods of increasing the biological activity of a bioactive agent by complexing the bioactive agent with a complexing agent. In one preferred embodiment, the...
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6696068 |
Cosmetic cream cleanser
A cosmetic cream cleansing composition is provided based on the presence of a silicate, a crosslinked carboxyvinyl polymer, a silicone copolyol sulfosuccinate and a carrier. The composition has a...
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6696089 |
Nanogel networks including polyion polymer fragments and biological agent compositions thereof
The present invention relates to nanogel networks having at least one cross-linked polyionic polymer fragment and at least one nonionic water-soluble polymer fragment, and compositions thereof,...
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6693093 |
Drug delivery systems for photodynamic therapy
The invention is generally related to the field of photodynamic therapy by use of photosensitizers and stabilized formulations of the photosensitizers. These formulations may be used to deliver a...
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6689387 |
Phytochemicals for treatment of mastalgia and endometriosis
New compositions are disclosed that comprise the phytochemical Diindolylmethane (DIM), as well as its precursor, Indole-3-carbinol (I3C), and cogener, 2-(Indol-3-ylmethyl)-3,3′diindolylmethane...
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6689299 |
Process for producing solid creatine dosage forms and dosage forms obtainable thereby
A process for producing solid creatine-containing dosage forms, wherein a) a mixture which comprises at least one thermoplastic, physiologically tolerated, water-soluble or water-swellable...
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6685963 |
Diphasic injection composition containing dispersed and continuous phases useful for reparative and plastic surgery
Biocompatible diphasic compositions are prepared comprising a dispersed phase suspended in a continuous phase, more particularly suitable for use as a filling material in reparative and plastic...
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6685929 |
Viscous scent lure for hunting
A viscous, non-liquid, non-gel scent lure for hunting, consisting of animal urine and a thickening agent. The thickening agent may comprise about 1% to about 7% by weight. The resulting viscosity...
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6685962 |
Gastroretentive controlled release pharmaceutical dosage forms
Pharmaceutical gastroretentive drug delivery systems for the controlled release of an active agent in the gastrointestinal tract are disclosed, which comprise: (a) a single- or multi-layered matrix...
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6682759 |
Manufacture of oral dosage forms delivering both immediate-release and sustained-release drugs
A method is disclosed for manufacturing a pharmaceutical tablet for oral administration, the tablet combining both immediate-release and prolonged-release modes of drug delivery and using an...
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6682760 |
Cross-linked collagen matrices and methods for their preparation
A method for preparing cross-linked collagen and cross-linked collagen products. The method includes incubating collagen in a solution including water, at least one polar solvent and at least one...
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6682893 |
Gel pad arrays and methods and systems for making them
Gel pads and gel pad arrays, and methods for making and using them, are disclosed. The gel pads preferably comprise an intelligent gel.
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6680070 |
Particulate blends and compacted products formed therefrom, and the preparation thereof
The dry blends comprise a powdery or finely-divided active ingredient such as a pharmaceutical, dietary supplement, agricultural chemical, water-treating agent or biocidal agent, and a micronized...
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6677362 |
Solid pharmaceutical dispersions
A novel solid pharmaceutical dispersion that improves the bioavailability of poorly water soluble drugs is produced by combining the drug with a polymer carrier such as polyvinylpyrrolidone. The...
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6676971 |
Embolic compositions
Embolic compositions comprising macromers having a backbone comprising a polymeric backbone comprising units with a 1,2-diol or 1,3-diol structure, such as polyvinyl alcohol, and pendant chains...
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6677313 |
Method for gene therapy using nucleic acid loaded polymeric microparticles
The invention involves methods and products for oral gene therapy. Genes under the control of promoters are protectively contained in microparticles and delivered to cells in operative form,...
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6673767 |
Gel composition and methods
Methods and compositions for systemically or locally administering by implantation a beneficial agent to a subject are described, and include, for example, compositions having burst indices of 8 ...
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6673371 |
Shear gel compositions
A composition which has a thickened fluid form comprises: (i) a first (shear gel) phase comprising at least one polymer which is capable of forming a gel, which polymer is present in the...
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6670454 |
Method for crosslinking porous biodegradable polymers
The present invention relates to crosslinking of porous materials made of biodegradable polymers. The method comprises: (a) placing a porous biodegradable polymer in a chamber; (b) introducing a...
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6667060 |
Pregelatinized starch in a controlled release formulation
The present invention concerns the use of pregelatinized starch to prevent dose-dumping from a hydrophilic controlled release formulation. It also concerns a hydrophilic controlled release...
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6667044 |
Cosmetic or dermatological gels based on microemulsions
Microemulsion gels a) based on water in oil type microemulsions, comprising an oil phase which is essentially composed of not easily volatile components, an aqueous phase containing one or more...
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6660300 |
Method of use of a biphasic controlled release delivery system for high solubility pharmaceuticals and method
A biphasic controlled release delivery system for pharmaceuticals which have high water solubility, such as the antidiabetic metformin HCl salt, is provided which provides a dosage form that has...
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6656502 |
Sustained-release prostaglandin I derivative preparation
A sustained release preparation of prostaglandin I derivatives, which is highly safe and has stable drug-releasing and absorption properties, is disclosed. In the orally administrable preparation,...
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