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5089267 |
Transdermal therapeutical system comprising physostigmine as active component and process for the production thereof
The present invention relates to a transdermal therapeutical system for the administration of physostigmine to the skin via a cover layer which is impermeable to active substances, a...
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5089205 |
Process for producing medical devices having antimicrobial properties
A process for imparting enhanced antimicrobial properties to medical devices, and particularly surgical and examination gloves, and to such gloves produced by the process. The process involves...
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5085867 |
Method for treating gastric ulcer with sulglycotide and hydrophilic polymer
The oral administration to an animal of sulglycotide `(a sulfoglycopeptide)` together with methylcellulose, pectin or tragacanth gum protects the animal against gastric ulcer.
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5082663 |
External adhesive preparation containing steroids
An external adhesive preparation comprising a steroid for treatment of skin diseases in admixture with an adhesive gel base comprising as essential components a water-soluble high molecular weight...
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5079003 |
Skin lotions and creams
Cosmetic creams or lotions comprising emulsions of shark liver oil, squalane, and squalene along with numerous other ingredients with therapeutic and synergetic effects on the skin are disclosed.
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5077051 |
Sustained release of active agents from bioadhesive microcapsules
Bioadhesives microcapsules capable of sustained release comprise xanthan gum, locust bean gum, a bulking agent and an active agent. The microcapsules are particularly useful for delivering...
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5069908 |
Crosslinked hydrogel and method for making same
A chemically crosslinked hydrogel includes an active ingredient for transdermal transport selected from the group of lidocainehydrochloride, hydrocortisone, menthol, and methyl salicylate and...
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5047248 |
Formulation for preparing sustained release drugs for oral administration
Pharmaceutical formulations are disclosed, adapted for preparing solid oral dosage forms (tablets, capsules, lozenges, etc.) having a regular and sustained release after administration. Said...
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5035893 |
Wound covering
The present invention relates to a wound covering comprising a sheet of biopolymeric material and a film of a polyurethane resin obtained by reacting a diisocyanate and a random copolymer of...
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5023082 |
Sustained-release pharmaceutical compositions
The present invention pertains to biodegradable sustained-release composins capable of achieving the sustained release of a pharmaceutical or other agent. The compositions can be formed into...
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5011692 |
Sustained pulsewise release pharmaceutical preparation
The invention relates to sustained pulsewise release pharmaceutical preparation which comprices drug-containing polymeric material layers (layers A) and polymeric material layers containing the...
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5008109 |
Vesicle stabilization
The present invention relates to a process of stabilizing micellular particles such as vesicles and increasing the shelf life by suspending the particles in a polymeric gel matrix. The invention...
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4994267 |
Transdermal acrylic multipolymer drug delivery system
A dermal composition comprising a drug, a multipolymer of ethylene-vinyl acetate, an acrylic polymer, and optionally one or more monomers, a natural or synthetic rubber and a tackifying agent. The...
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4988512 |
Nasal pharmaceutical compositions
Solid nasal inserts of calcitonin and other peptides have particularly interesting drug absorption profiles.
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4970298 |
Biodegradable matrix and methods for producing same
This invention relates to a biodegradable collagen matrix having a pore size and morphology which enhances the healing of a wound. It further relates to a process for preparing the matrix. One...
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4963367 |
Drug delivery compositions and methods
Drug delivery compositions yeild new and unexpected degrees of stabilization, solubilization and delivery of incorporated medicaments, drugs, or other physiologically-active compounds. The...
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4946684 |
Fast dissolving dosage forms
A pharmaceutical dosage form is provided which disintegrates rapidly in water having an open matrix network structure comprised of mannitol and a natural gum and which can be used particularly for...
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4937079 |
Pharmaceutical composition for the prophylaxis and therapy of gastric ulcer
The combination of a hydrophilic polymer with sulglycotide in pharmaceutical compositions for orally use enhances the anti-ulcer activity of sulglycotide.
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4931287 |
Heterogeneous interpenetrating polymer networks for the controlled release of drugs
A heterogeneous interpenetrating polymer network is provided for use in the controlled release of drugs. The network is a heterogeneous matrix that is formed from a hydrophilic component such as...
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4927636 |
Association complex comprising pullulan and polyethylene glycol, and preparation and uses of the same
Pullulan forms an association complex with PEG in a hydrous system. The assocation complex, as well as its pullulan and PEG components, exerts a decreased solubility in water. The association...
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4921757 |
System for delayed and pulsed release of biologically active substances
A system for controlled release both in vivo and in vitro of entrapped substances, either at a constant rate over a period of time or in discrete pulses, is disclosed. Biologically active...
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4914084 |
Composition and method for introducing heme, hemoproteins, and/or heme-hemoprotein complexes into the body
A liquid coacervate composition and a method of introducing heme, hemoproteins and/or heme-hemoprotein complexes into the body. The liquid composition, comprising an oxygen-carrying molecule...
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4894232 |
Base for mucosal and denture adhesive pastes, a process for the preparation thereof, and pastes having this base
A base for mucosal and denture adhesive pastes, a process for the preparation thereof, and pastes having this base. A base for mucosal and denture adhesive pastes, pastes having this base, and a...
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4891226 |
Pharmaceutical which can be administered nasally, a process for its preparation, and its use
A pharmaceutical which is for nasal administration and contains a high molecular weight active compound and a gel-forming agent and, where appropriate, auxiliaries is described. High molecular...
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4882151 |
Confectionery delivery system for antihistimines
A chewable delivery system for actives comprising: (a) an active pre-coated with at least one material selected from the group consisting of lecithin, polyoxyalkylenes having chain lenghts of...
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4857331 |
Sugarless pectin delivery system
A sugarless ingestible gel confectionary delivery system which includes a pectin gel component, an algin gel component and a polymer network gel component in amounts sufficient to form a gel...
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4853225 |
Process for implanting a medicament depot
The invention relates to an implantable medicament depot comprising physiologically acceptable excipients and at least one delayed release active compound which is a chemotherapeutic of the gyrase...
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4851231 |
System for delivering drug in selected environment of use
A delivery system is disclosed for delivering an agent to a selected environment of use having a pH of greater than 3.5.
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4845042 |
Adjuvant for immunization
The invention provides an immunizing agent or preparation e.g. a vaccine for parenteral administration comprising particles of coalesced and covalently interlinked physiologically compatible...
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4842866 |
Slow release solid preparation
A controlled, slow release, solid pharmaceutical preparation includes at least one active ingredient and a blend of sodium alginate and sodium-calcium alginate.
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4842761 |
Compositions and methods for controlled release of fragrance-bearing substances
Laundering compositions containing particulate olfactory polymers which provide for the controlled release of olfactory compositions such as perfumes, the particulate olfactory polymers comprising...
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4837255 |
Palatable hypocholesterolaemic gel formulation containing a pharmaceutically acceptable non-digestible anion exchange resin
A gel formation for oral administration having improved palatability comprising an effective hypocholesterolaemic amount of a uniform gelled dispersion of (a) between about 8 and about 20...
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4832994 |
Anti-smoking oral composition
Anti-smoking oral preparations are provided containing a silver compound as the anti-smoking agent and a sweetener in which the silver compound is present in amounts of from 0.1 mg. to 2.5 mg. and...
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4816254 |
Ointment for treating skin irritations
The invention provides an ointment composition for treating skin irritations such as diaper rash and decubitus. The composition includes zinc oxide, boric acid, karaya gum, peruvian balsam, cod...
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4814168 |
Transdermal multipolymer drug delivery system
A dermal compositon comprising a drug, a multi-polymer of vinyl acetate, polyethylene and optionally one or more monomers, a natural or synthetic rubber and a tackifying agent. The ratio of the...
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4814179 |
Floating sustained release therapeutic compositions
Non-compressed sustained release tablets which will float on gastric fluid are described. The tablets comprise a hydrocolloid gelling agent, a therapeutically acceptable inert oil, the selected...
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4814183 |
Device for the controlled release of drugs with Donnan-like modulation by charged insoluble resins
The instant invention is directed to a drug delivery device for the controlled release of beneficial agents and drugs into an environment of use comprising: (A) a core composition comprising ...
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4812445 |
Starch based encapsulation process
Virtually any material may be encapsulated in a starch matrix by combining the material with a high temperature-stabilized dispersion of starch, optionally in the presence of salt. The...
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4781926 |
Transdermal therapeutic composition
Transdermal dosage compositions are prepared from hydrated poly(vinyl alcohol) gels and pharmacologically active substances without any chemicals such as crosslinking agents and catalysts. Heating...
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4776850 |
Nitrate-containing plaster
A self-adhesive plaster with glycerol trinitrate in a self-adhesive composition of a saturated rubber and a tackifying resin for transdermal administration is characterized in that the saturated...
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4755389 |
Chewable capsules
A hard gelatin capsule is filled with a chewable composition containing an ingredient for buccal absorption or having buccal activity.
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4746513 |
Microcapsules and method for their production
Dump release microcapsules are formed of a water-reswellable gel having dispersed therein a sorbtive filler material having a median particle size of not more than 1 micron, such as fumed or...
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4676976 |
Konjak mannan-containing reversible gel
A konjak mannan-containing reversible gel comprising konjak mannan and xanthane gum and free of any alkali agent for solidifying konjak mannan and a process for producing the reversible gel and a...
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4501835 |
Polyacrylic acid/chitosan polyelectrolyte complex
A novel composition of matter comprising a polyacrylic acid/chitosan complex. This complex is particularly useful as a membrane or filter.
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4371516 |
Articles for carrying chemicals
The invention relates to shaped articles carrying chemicals, particular to pharmaceutical dosage forms carrying pharmaceuticals, which disintegrate rapidly in water. The shaped articles comprise an...
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4359483 |
Process for producing a multi-layered slow release composite
A process is herein disclosed for producing a multi-layered slow release composite comprising: a first step wherein one or more physiologically active substances is mixed with one member selected...
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4344857 |
Encapsulation by entrapment
Chemical biological agents to be encapsulated are dissolved or dispersed in an aqueous solution of polyhydroxy polymer xanthate. Simultaneous addition of a strong acid and a coupling agent to the...
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4307717 |
Sterile improved bandage containing a medicament
A flexible, liquid absorbent, adhesive bandage includes a backing element and a substrate attached to the backing element. The substrate comprises a homogeneous, hydrophilic, stable matrix...
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4306551 |
Sterile improved bandage and sealant
A flexible, liquid absorbent, adhesive bandage includes a backing element and a substrate attached to the backing element. The substrate comprises a homogeneous, hydrophilic, stable matrix...
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4230687 |
Encapsulation of active agents as microdispersions in homogeneous natural polymeric matrices
A method for effectively encasing an active agent such as a chemical compound, a seasoning, a flavoring, or a nutrient such as vitamins and minerals, including liquids, as a time-stable but...
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