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9220820 Hydrophobic cross-linked gels for bioabsorbable drug carrier coatings  
Coatings for medical devices, methods of making the coatings, and methods of using them are described.
9028871 Resorbable ceramics with controlled strength loss rates  
Particular aspects provide bioresorbable and biocompatible compositions for bioengineering, restoring or regenerating tissue or bone, comprising a three-dimensional porous or non-porous scaffold...
9028882 Nutraceutical gels  
A nutriceutical food product includes a solid polymeric matrix and a liquid combined into a gel. The nutriceutical food product may include an immune modulator, such as transfer factor and/or a...
9023392 Methods of administering a dermatological agent to a subject  
Methods for administering a dermatological agent to a subject are provided. In the subject methods an effective amount of a topical formulation of the dermatological agent is topically applied to...
9011915 Conveniently implantable sustained release drug compositions  
This invention provides for biocompatible and biodegradable syringeable liquid, implantable solid, and injectable gel pharmaceutical formulations useful for the treatment of systemic and local...
9011899 Methods and devices for cellular transplantation  
Devices and methods for transplanting cells in a host body are described. The cell comprises a porous scaffold that allows ingrowth of vascular and connective tissues, a plug or plug system...
9011917 Method for enzymatic treatment, device and kit used the same  
One embodiment provides a method for enzymatic treatment, including the steps of forming a closed space on a local tissue area with a device and infusing an enzyme solution into the closed space...
9011891 Water dispersible formulation for delivery of biocontrol fungi to reduce aflatoxin  
A formulation containing conidia of non-toxigenic strains of fungi is a useful biocontrol agent for preventing toxin contamination in agricultural commodities, especially those for human and...
9011914 Hetero-assembled hydrogels  
A two-component, molecular-recognition gelation strategy that enables cell encapsulation without the need for environmental triggers is provided. The two components, which in one example contain...
9012530 Bioadhesive for periodontal gingival and/or bone tissues  
The invention is directed to an adhesive strip, particularly an adhesive strip or bandage for use in periodontal treatments. The biocompatible adhesive strip comprises a flexible barrier with a...
9006199 Methods and compositions for treating prostate cancer  
Treatment of prostate cancer by regional and prolonged release of one or more nucleotide-based RNAi agents is provided.
9005648 Inorganically surface-modified polymers and methods for making and using them  
In alternative embodiments, the invention provides articles of manufacture comprising biocompatible nanostructures comprising PolyEther EtherKetone (PEEK) surface-modified (surface-nanopatterned)...
9005662 Biocompatible polyelectrolyte complexes and methods of use  
An article comprising a polyelectrolyte complex comprising an interpenetrating network of at least one predominantly positively charged polyelectrolyte polymer and at least one predominantly...
8999389 Bioresorbable controlled-release composition  
A novel method for the preparation of a highly densified and at least partly, preferably fully or almost fully hydrated ceramic for use in the preparation of a pharmaceutical composition notably...
8999297 Hemostatic agent  
A generally non-acidic hemostatic agent, having a relatively neutral pH comprising a magnesium compound, such as a magnesium chloride, a magnesium sulfate and/or a magnesium acetate based...
8999377 System for forming a biocompatible foam using polymerizable alpha(1-4)glucopyranose polymers and gas-producing component  
Biocompatible foams having excellent physical and chemical properties are described. The biocompatible foams can be formed in situ or applied as a pre-formed foam for the treatment of tissue. The...
8992978 Material compositions which comprise adult stem cells obtained from exocrine glandular tissue, in particular for use in regenerative medicine  
The invention relates to material compositions comprising adult stem cells obtained from exocrine gland tissue and a supporting matrix having the shape of a thread structure and/or of a net. The...
8992977 Multi-day delivery of biologically active substances  
Compositions and methods for modifying biologically active substances to achieve multi-day delivery of such substances, particularly through oral or parenteral administration, are disclosed. The...
8992613 Unshrunken tissue equivalent and methods for producing such an unshrunken tissue equivalent  
The invention relates to a method for producing an unshrunken tissue equivalent. Said method is comprising in that: a mixture is produced that contains at least one element of an extracellular...
8992979 Sustained-release drug carrier composition  
The present invention provides compositions for extended release of one or more active ingredients, comprising a lipid-saturated matrix formed from a non-biodegradable polymer or a...
8986733 Materials and methods for nerve repair  
The subject invention pertains to compositions and methods for promoting repair of damaged nerve tissue. The compositions and methods of the subject invention can be employed to restore the...
8986735 Solid dosage form containing a taste masked active agent  
A solid dosage form containing a taste masked active agent is provided. The solid dosage form may be provided as a water soluble film that is disintegrable in the oral cavity to deliver and...
8980324 Silicon dioxide nanoparticles and the use thereof for vaccination  
The invention relates to ultrasmall, monodisperse nanoparticles comprising silicon dioxide to the surface of which at least one antigen is attached. The nanoparticles can be used for the...
8980278 Bio-functionalized stimulus-responsive dissolvable PEG-hydrogels  
The present invention is directed to a bio-functionalized stimulus-responsive dissolvable PEG-hydrogel. This inventive stimulus-responsive dissolvable PEG-hydrogel comprises a matrix of...
8980323 Hydrophilic matrix containing poorly water-soluble compound and method for producing the same  
It is an object of the present invention to solve the problem of precipitation of a poorly water-soluble compound in a hydrophilic matrix upon inclusion of the poorly water-soluble compound in the...
8980322 Controlled release composition  
The present invention provides a controlled release composition showing release of an active ingredient (proton pump inhibitor) controlled in two or more steps at different release rates, which...
8974827 Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer  
A pharmaceutical composition comprises nanoparticles comprising a poorly water-soluble drug, a poorly aqueous soluble non-ionizable cellulosic polymer, and a poorly aqueous soluble polymeric...
8974826 Nanoparticle film delivery systems  
A therapeutic or bioeffecting film delivery system which includes nanoparticles having actives bound to or associated with the nanoparticles and which when administered allow the active to perform...
8974814 Layered drug delivery polymer monofilament fibers  
The present invention is directed generally to a layered polymeric monofilament fiber drug delivery device, where each layer of the device can contain a different polymer, drug, additive, or any...
8975075 Hemostatic device  
A hemostatic device, method of making, and method of using for internal and external applications to wounds in the body of a patient to induce hemostasis at an anatomical site.
8962029 Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications  
The presently disclosed subject matter relates to nitric oxide-releasing particles for delivering nitric oxide, and their use in biomedical and pharmaceutical applications.
8962023 UV cured gel and method of making  
A method of UV curing and corresponding resulting non-polymeric cross-linked gel are provided. The cross-linked gel can be combined with a medical device structure. The cross-linked gel can...
8962026 Nanoemulsion therapeutic compositions and methods of using the same  
The present invention relates to therapeutic nanoemulsion compositions and to methods of utilizing the same. In particular, nanoemulsion compositions are described herein that find use in the...
8956636 Methods and compositions for treating postoperative pain comprosing ketorolac  
Methods and compositions are provided for reducing, treating or preventing postoperative pain or inflammation in a patient in need of such treatment, the methods and compositions comprising...
8956682 Hydrophilic polymeric coatings for medical articles with visualization moiety  
The invention is directed to medical device coatings, such as coated guidewires and catheters, containing a visualization moiety providing color to the coating in ambient or applied light. The...
8956658 Nitric oxide-releasing particles for nitric oxide therapeutics and biomedical applications  
The presently disclosed subject matter relates to nitric oxide-releasing particles for delivering nitric oxide, and their use in biomedical and pharmaceutical applications.
8951559 Nano-structured thixotropic inorganic peeling gels  
A composition, a method, and a kit are provided for chemical skin peeling, based on nano-structured thixotropic inorganic gels, which have a higher potency and are less irritant of the...
8951548 Acrylic hydrogels with pendant cyclodextrins, preparation method thereof and use of same as release systems and contact lens components  
The invention relates to acrylic hydrogels with pendant cyclodextrins, the preparation and application thereof as release systems and components of contact lenses. The method for obtaining acrylic...
8945619 Shell-and-core dosage form approaching zero-order drug release  
Drugs are formulated as oral dosage forms for controlled release in which the release rate limiting portion is a shell surrounding the drug-containing core. The shell releases drug from the core...
8945535 Implant for the repair of a cartilage defect and method for manufacturing the implant  
For the repair of a cartilage defect in a human or animal patient use is made of an implant comprising an implant body including a natural cartilage matrix and being coated with cells having a...
8945600 Methods of delivering pharmaceutical agents  
Provided are methods of delivering at least one pharmaceutical agent to the central nervous system (CNS) of a subject, methods of treating a neurological disorder or pain in a subject that include...
8940331 Hydrogels, methods of making hydrogels, methods of using hydrogels, and methods of isolating, trapping, attracting, and/or killing cancer cells  
Embodiments of the present disclosure provide for hydrogels, methods of making hydrogels, methods of using hydrogels, methods of isolating, trapping, attracting, and/or killing cancer cells, and...
8940336 Polymer particles prepared from polymerisable alkylene glycol (meth) acrylate monomers  
The invention provides polymer particles that are obtainable by a method selected from emulsion methods, diffusion methods and evaporation methods carried out in the presence of...
8936812 Tamper-resistant oral opioid agonist formulations  
Disclosed is a substantially non-releasable form of an opioid antagonist containing the opioid antagonist combined with one or more pharmaceutically acceptable hydrophobic material(s) such that...
8936811 Device coated with glycogen particles comprising nucleic acid complexes  
Embodiments of the invention include particles with nucleic acid complexes, medical devices including the same and related methods. In an embodiment, the invention can include a method of making a...
8936825 Method and system for forming a pharmaceutical product directly onto a packaging surface  
The present invention relates to a method for forming a pharmaceutical product, such as a dissolvable film dosage form, onto a surface. Particularly, the present invention relates to a method of...
8932622 Tissue coating for preventing undesired tissue-to-tissue adhesions  
Disclosed herein are a kit and a method for forming a tissue coating that prevents undesired tissue-to-tissue adhesions resulting from trauma, surgery, infection, or other stimulus. The tissue...
8927028 Pharmaceutical composition containing coated, floating particles  
A dosage form exhibiting delayed transit time through the GI tract. The dosage form comprises a plurality of buoyant particles, each comprising an inner drug-containing core, an intermediate layer...
8927016 Producing a sustained-release preparation  
This invention provides a production method for a solid sustained-release preparation, characterized in that a sustained-release preparation (a sustained-release preparation suspension) is...
8920868 Process for preparing a ceramic body having a surface roughness  
A process for preparing a ceramic body having a surface roughness, said process comprising the step of depositing particles of a ceramic material on the surface of a ceramic basic body. The...