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6706285 |
Enteric coated formulation of a benzimidazole derivative and method for preparation thereof
Disclosed are an enteric coated formulation of a benzimidazole derivative comprising a core and a film of an enteric coating agent on the surface thereof, the core containing a complex of the...
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6706034 |
Process for agent retention in biological tissues
An increase in agent residence time at a tissue site is provided for by the presence of a barrier. The barrier is a separate entity from the agent when introduced to the tissue. A binding member is...
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6703011 |
Application of film forming technology to fragrance control release systems; and resultant fragrance control release systems
Described is a fragrance control release system which is an emulsifier-free, single phase, nonporous, continuous, permeable polymeric film having a substantially uniform thickness of from about 1...
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6703035 |
Absorbable &egr -caprolactone copolymers
This invention deals with crystalline, nitrogen copolyester lubricant coating devices comprising sutures, wherein said lubricant comprises a triaxial copolyester chain with a central nitrogenous...
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6703039 |
Reversible gelling system for ocular drug delivery
The invention provides an ophthalmic aqueous composition for topical administration, comprising: (a) a block copolymer of propylene oxide and ethylene oxide in concentration sufficient to provide...
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6703045 |
Composition and method for maintaining blood glucose level
A composition useful for reducing serum glucose levels by an oral controlled release system and a method for treating diabetes in a human being by controlling the blood glucose level (BGL) and...
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6699498 |
Transdermal therapeutic systems having improved stability and their production
This invention provides for, inter alia, a transdermal therapeutic system comprising at least one therapeutically active substance, which is oxidizable by hydroperoxides, wherein the amount of...
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6699502 |
Pharmaceutical compositions for controlled release of active substances
The present invention is directed a pharmaceutical composition which can be administered orally, allowing for the controlled release of at least one active substance. The composition includes at...
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6699505 |
Method of increasing the efficacy of antibiotics by compexing with cyclodextrins
The present invention provides methods of increasing the biological activity of a bioactive agent by complexing the bioactive agent with a complexing agent. In one preferred embodiment, the...
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6696073 |
Shaped load-bearing osteoimplant and methods of making same
A load-bearing osteoimplant, methods of making the osteoimplant and method for repairing hard tissue such as bone and teeth employing the osteoimplant are provided. The osteoimplant comprises a...
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6696258 |
Mesoporous materials and methods of making the same
Mesoporous materials and a method for making such materials is disclosed in which the mesoporous materials are made by forming an aqueous solution having an organometallic compound; adding a...
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6696089 |
Nanogel networks including polyion polymer fragments and biological agent compositions thereof
The present invention relates to nanogel networks having at least one cross-linked polyionic polymer fragment and at least one nonionic water-soluble polymer fragment, and compositions thereof,...
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6692738 |
Delivery of therapeutic biologicals from implantable tissue matrices
Normal cells, such as fibroblasts or other tissue or organ cell types, are genetically engineered to express biologically active, therapeutic agents, such as proteins that are normally produced in...
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6689388 |
Microencapsulated delivery system for high viscosity fluids
Disclosed is a process for producing powders from high viscosity fluids including mixing a mixture comprising a high viscosity fluid and at least one absorbing agent until a dry dispersion is...
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6689373 |
Devices and methods for pain management
The invention features devices and methods for the systemic delivery of fentanyl or a fentanyl congener (e.g., sufentanil) to treat pain. In the present invention, a drug formulation comprising...
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6685951 |
Administration of dihydroergotamine as a sublingual spray or aerosol for the treatment of migraine
The present invention is an improvement in the treatment of migraine headaches. By administering dihydroergotamine as a sublingual spray or aerosol, major limitations of past treatments are...
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6685929 |
Viscous scent lure for hunting
A viscous, non-liquid, non-gel scent lure for hunting, consisting of animal urine and a thickening agent. The thickening agent may comprise about 1% to about 7% by weight. The resulting viscosity...
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6685962 |
Gastroretentive controlled release pharmaceutical dosage forms
Pharmaceutical gastroretentive drug delivery systems for the controlled release of an active agent in the gastrointestinal tract are disclosed, which comprise: (a) a single- or multi-layered matrix...
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6682756 |
Individually dosed foil-form presentation which decomposes rapidly on contact with liquid and contains an active substance, in particular an aromatic substance
Individually dosed active substance-containing and, in particular, aromatic-containing, film-shaped administration form, rapidly disintegrating upon contact with a liquid, wherein the aromatic is...
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6682760 |
Cross-linked collagen matrices and methods for their preparation
A method for preparing cross-linked collagen and cross-linked collagen products. The method includes incubating collagen in a solution including water, at least one polar solvent and at least one...
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6682754 |
Ovo delivery of an immunogen containing implant
The disclosure provides a method for administering an agent to an avian species by in ovo delivery of an implant releasably containing the agent. In one embodiment, the method is particularly...
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6680070 |
Particulate blends and compacted products formed therefrom, and the preparation thereof
The dry blends comprise a powdery or finely-divided active ingredient such as a pharmaceutical, dietary supplement, agricultural chemical, water-treating agent or biocidal agent, and a micronized...
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6676970 |
Subcutaneous osteoporosis compositions
The invention is concerned with a pharmaceutical preparation for subcutaneous, parenteral administration, which contains bisphosphonic acids or their salts as the active substance, as well as the...
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6676971 |
Embolic compositions
Embolic compositions comprising macromers having a backbone comprising a polymeric backbone comprising units with a 1,2-diol or 1,3-diol structure, such as polyvinyl alcohol, and pendant chains...
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6676966 |
Extended release metformin hydrochloride formulations
An extended release formulation of metformin hydrochloride is disclosed. The metformin hydrochloride is encased within polymeric film layers providing for gradual release of the metformin...
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6673371 |
Shear gel compositions
A composition which has a thickened fluid form comprises: (i) a first (shear gel) phase comprising at least one polymer which is capable of forming a gel, which polymer is present in the...
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6669958 |
Gel delivery vehicles for anticellular proliferative agents
Methods and compositions are provided for the treatment of a host suffering from a cellular proliferative diease. In the subject methods, antiproliferative agents are administered in a...
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6670454 |
Method for crosslinking porous biodegradable polymers
The present invention relates to crosslinking of porous materials made of biodegradable polymers. The method comprises: (a) placing a porous biodegradable polymer in a chamber; (b) introducing a...
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6669957 |
Galenic formulations fast disintegrating in the mouth and method for preparing same
The invention relates to pharmaceutical dosage forms with rapid disintegration in the mouth and to their process of preparation. These pharmaceutical dosage forms comprise at least one active...
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6669963 |
Stable particle in liquid formulations
A stable particle in liquid formulation comprising a discontinuous phase of microparticles is suspended in a continuous phase which is a non-aqueous liquid, preferably biocompatible in which the...
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6667057 |
Levofloxacin antibiotic product, use and formulation thereof
An antibiotic product, in particular levofloxacin, is comprised of at least three dosages forms, each of which has a different release profile, with the C max for the antibiotic product being...
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6667042 |
Fluroquinilone antibiotic product, use and formulation thereof
An antibiotic product, in particular a fluroquinilone such as ciprofloxacin, is comprised of at least three dosages forms, each of which has a different release profile, with the C max for the...
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6667044 |
Cosmetic or dermatological gels based on microemulsions
Microemulsion gels a) based on water in oil type microemulsions, comprising an oil phase which is essentially composed of not easily volatile components, an aqueous phase containing one or more...
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6667050 |
Chewable oral contraceptive
The present invention relates to a chewable, palatable oral contraceptive tablet, comprising an oral contraceptive agent, a chewable carrier suitable for human consumption, and not comprising a...
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6663890 |
Metronidazole antibiotic product, use and formulation thereof
An antibiotic product, in particular metronidazole, is comprised of at least three dosages forms, each of which has a different release profile, with the C max for the antibiotic product being...
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6663891 |
Erythromyacin antibiotic product, use and formulation thereof
An antibiotic product, in particular an erythromyacin, is comprised of at least three dosages forms, each of which has a different release profile, with the C max for the antibiotic product being...
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6663883 |
Matrix adhering to nasal mucosa
This invention provides a matrix adhering to the nasal mucosa which allows improved transfer into the brain of a drug exerting its effect in the brain and is capable of continuously supplying the...
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6660277 |
Gel matrix non-emulsion composition containing two clay gels
A cosmetic composition comprising a lipophilic clay gel and a hydrophilic clay gel. The two gels are combined or formed in situ to create a gel matrix. This matrix functions like an emulsion to...
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6656487 |
Composition containing fibers and a dispersing copolymer
The invention relates to a composition containing fibers and a copolymer comprising carboxylate groups and polydimethylsiloxane groups. The composition according to the invention may especially...
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6656503 |
Pharmaceutical tablet comprising an NSAID and misoprostol
A pharmaceutical tablet comprising a core and a film coating wherein the core comprises an NSAID and the film coating comprises a polymer and misoprostol.
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6656508 |
Sustained-release alginate gels
The present invention relates to sustained-release formulations using alginate gel beads and methods thereof.
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6656507 |
Aqueous dispersion suitable for the production of coatings and binders for solid oral drugs
An aqueous dispersion for the production of binders or coatings for solid oral drugs having a water content of 90-40 wt. % and a solids portion of 10-60 wt. %, whereby said solids portion is...
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6652883 |
Tissue bulking and coating compositions
Compositions comprising macromers having a backbone comprising units having a 1,2-diol and/or 1,3-diol structure for tissue bulking and coating. Such polymers include poly(vinyl alcohol) (PVA) and...
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6652886 |
Biodegradable cationic copolymers of poly (alkylenimine) and poly (ethylene glycol) for the delivery of bioactive agents
A biodegradable, novel cationic coopolymer comprising a a poly(alkylenimine)(PAI), a hydrophilic polymer, and a biodegradable linker, wherein the biodegradable linker covalently links the PAI and...
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6652876 |
Active substance patch, kind to the skin, for transdermal administration of nonsteroidal antirheumatics
An active substance matrix patch for controlled delivery of nonsteroidal antirheumatics to the skin, comprising a flexible cover layer and a water insoluble, pressure sensitively adhesive active...
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6652840 |
Bleeding control and healing aid compositions and methods of use
A composition is disclosed which has been shown to stop or control bleeding and seal open small blood vessels while accelerating the healing process of abraded oral “gum” and other “skin”...
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6649145 |
Compositions and method of tissue superoxygenation
Disclosed are methods and compositions for increasing tissue oxygen levels by administration of superoxygenated compositions of tissue surfaces. The methods are applicable to treatment of a wide...
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6646014 |
Organic compounds
The present invention concerns a method for the control of various diseases in bee-hives by applying to the bee-hives an effective amount of an essential oil in a slow-release formulation whereby...
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6645510 |
Method of treating topical ailments
A composition capable of forming a film that ionically bonds to the skin comprising one or more active agents, a nonionic or substantially nonionic first film forming component, one or more...
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6641842 |
Thermoplastic articles exhibiting high surface-available silver
Improvements in increasing the amount of surface-available silver in thermoplastic articles comprising certain silver-containing antimicrobial agents. Such an invention requires the incorporation...
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