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6780411 |
Tissue sealant compositions
Tissue sealant compositions containing human recombinant fibrinogen, human recombinant factor XIII and human recombinant thrombin. Also disclosed are preferred formulations and uses therefore.
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6780427 |
Reduction of adhesions using controlled delivery of active oxygen inhibitors
SOD and other active oxygen inhibitors are directly applied in combination with a barrier material at local sites of tissue injury to prevent or decrease formation of adhesions and undesirable...
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6773720 |
Mesalazine controlled release oral pharmaceutical compositions
Controlled-release oral pharmaceutical compositions containing as active ingredient 5-amino-salicylic acid, comprising: a) an inner lipophilic matrix consisting of substances with a melting point...
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6767928 |
Mineralization and biological modification of biomaterial surfaces
Disclosed are advantageous methods for patterning and/or mineralizing biomaterial surfaces. The techniques described are particularly useful for generating three-dimensional or contoured bioimplant...
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6764994 |
Growth/differential factor of the TGF-B family
The invention concerns a protein of the TGF-β family, the DNA coding therefor and a pharmaceutical composition containing the protein.
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6761908 |
Collagen preparation for the controlled release of active substances
A collagen preparation for the controlled release of active substances is characterized in that it has mixtures of acid-insoluble collagens with different molecular weight distributions.
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6756217 |
Glass composite materials containing alkoxosilane derivative having alterable charge, hydrophobic and hydrophilic groups
A porous glass composite material is prepared comprising a gel containing water and a polymeric network containing at least one alkoxosilane derivative having a group of alterable charge, a...
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6756060 |
Anti-inflammatory and antimicrobial uses for bioactive glass compositions
Compositions and methods for treating wounds to significantly reduce the healing time, reduce the incidence of scar formation, improve the success of skin grafts, reduce the inflammatory response...
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6753015 |
Microparticle compositions and methods for the manufacture thereof
Microparticles with adsorbed complexes of macromolecule and detergent, methods of making such microparticles, and uses thereof, are disclosed. The microparticles comprise a polymer, such as a...
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6753006 |
Paclitaxel-containing formulations
In accordance with the present invention, there are provided compositions and methods useful for the in vivo delivery of a pharmaceutically active agent, wherein the agent is associated with a...
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6753013 |
Pharmaceutical composition
A pharmaceutical composition for dermal use, wherein the composition has a first pharmacologically active component A consisting of at least one vitamin D or vitamin D analogue, and a second...
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6748653 |
Method of making a temporary medical lead having biodegradable electrode mounting pad loaded with therapeutic drug
A method of making a temporary medical electrical lead for pacing or defibrillating a heart of a patient. The method comprises providing at least one electrical conductor having proximal and distal...
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6749866 |
Modulated release from biocompatible polymers
The present invention relates to a composition for the modulated release of a biologically active agent. The composition comprises a biocompatible polymeric matrix, a biologically active agent...
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6748954 |
Drug release from polymer matrices through mechanical stimulation
A method for drug delivery and polymer matrix suited to the method are disclosed. The polymer matrix has reversibly bound thereto a drug or combination of drugs, and is capable of releasing the...
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6749865 |
Modification of biopolymers for improved drug delivery
A biologically active conjugate is disclosed comprising a biopolymer and a therapeutic agent joined by a disulfide bond. The conjugate, when formulated in a pharmaceutical composition with a...
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6746667 |
Adhesive treatment for tinea pedis
A method of treating or preventing tinea pedis, commonly known as Athlete's Foot, includes applying a polymerizable monomer adhesive composition to an area of skin afflicted with or susceptible to...
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6743445 |
Low temperature coatings
A method of coating an active material is provided. The method comprises contacting an active material with a film-forming composition comprising an aqueous dispersion of an amylose-alcohol...
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6743442 |
Melt-extruded orally administrable opioid formulations
Bioavailable sustained release oral opioid analgesic dosage forms, comprising a plurality of multiparticulates produced via melt extrusion techniques are disclosed.
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6743446 |
Methods for stabilizing biologically active agents encapsulated in biodegradable controlled-release polymers
Methods for reducing or inhibiting the irreversible inactivation of water-soluble biologically active agents in biodegradable polymeric delivery systems which are designed to release such agents...
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6743448 |
Topical testosterone formulations and associated methods
A topical testosterone formulation is disclosed. In one aspect, the formulation may include a therapeutically effective amount of micronized testosterone, an arginine ingredient, and a tocopherol...
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6743439 |
Ophthalmic compositions containing copolymers of sulfonated styrene and maleic anhydride
Aqueous pharmaceutical solution compositions preserved with a cationic preservative and comprising a cationic drug and a sulfonated styrene/maleic anhydride copolymer are disclosed. The...
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6737068 |
Wipe formulation
The present invention relates to a liquid formulation for a feminine wipe. The preferred formulation has an anti-irritant agent, a pH adjuster namely citric acid, and at least one preservative.
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6733782 |
Core tablet for controlled release of gliclazide after oral administration
The invention relates to a matrix tablet for the prolonged release of gliclazide which ensures continuous and consistent release of the active ingredient after administration by the oral route, the...
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6733790 |
Microcapsules and processes for making the same using various polymers and chitosans
A microcapsule having a mean diameter of from about 0.1 to about 5 mm, a membrane and a matrix containing at least one active principle wherein the microcapsule is the product of the process...
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6733786 |
Somatotropin composition with improved syringeability
The present invention relates to an improved somatotropin composition consisting of somatotropin having in vivo, at least one of lipid-soluble vitamins and at least one of pharmaceutically...
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6733785 |
Moisture-sensitive preparation of percutaneous absorption type
The invention relates to a percutaneous absorption preparation which comprises a supporting body, a medicine storage layer, a permeation controlling film, a layer of an adhesive and a release liner...
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6730317 |
Patch, a kit constituted by a patch and a receptacle and a method
A patch comprising a matrix having adhesive properties in the dry state and containing at least one active substance, said matrix being attached via one face to a backing and being for application...
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6730320 |
Tetracycline antibiotic product, use and formulation thereof
An antibiotic product, in particular a tetracycline, such as doxycycline, is comprised of at least three dosages forms, each of which has a different release profile, with the C max for the...
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6730667 |
Iontophoresis disc pain blocker
Treatment of pain syndromes utilizes a topical polypharmaceutical preparation of phenoxybenzamine, ketamine, gabapentin, nifedipine, carbamazepine, or combinations of them. Other suitable...
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6727204 |
Use of crosslinked polymers as anti-leaching agents
The invention concerns the use, in an aqueous spray mixture comprising a phytosanitary formulation, of an anti-leaching agent comprising: at least a polyhydroxyl and/or polycarboxyl polymer or...
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6726932 |
Fatty acid-containing composition
The present invention provides a composition for enhancing the pharmacological activity of a water-soluble silicate polymer which comprises the water-soluble silicate polymer and a saturated fatty...
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6726934 |
Micro-particulate and nano-particulate polymeric delivery system
The present invention provides a method of making particles useful in drug delivery, comprising the steps of: contacting polyanionic polymers with cations in a stirred reactor so that polyanions...
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6726928 |
Process for preparing solid dosage forms for unpalatable pharmaceuticals
A process for the preparation of a rapidly disintegrating dosage form a pharmaceutically active substance which has an unacceptable taste wherein there is formed a solution or a suspension in a...
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6723347 |
Proces for producing protein powder
A process for conveniently producing a stable protein powder retaining the higher-order structure at a high level which comprises freezing a protein-containing solution at a cooling rate of about...
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6723341 |
Antibiotic product, use and formulation thereof
An antibiotic product is comprised of at least three dosages forms, each of which has a different release profile, with the C max for the antibiotic product being reached in less than about twelve...
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6723349 |
Polyoxometalate materials, metal-containing materials, and methods of use thereof
The invention relates to a polyoxometalate topical composition for removing a contaminant from an environment, comprising a topical carrier and at least one polyoxometalate, with the proviso that...
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6723337 |
Transdermal drug delivery system for anti-inflammatory analgesic agent comprising diclofenac diethylammonium salt, and the manufacturing method thereof
The invention herein relates to a transdermal drug delivery systern for anti-Inflammatory analgesic. agent comprising diclofenac diethylammonium salt, wherein a backing film ( 1 ), a matrix layer (...
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6723344 |
Controlled release of non heparin-binding growth factors from heparin-containing matrices
Matrices that support cell adhesion and growth are disclosed that deliver low heparin-binding affinity growth factor protein peptides in a controlled manner. These matrices comprise covalently or...
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6723306 |
Article for applying artificial tanning agent and method of making
An article for applying a skin care product, particularly an artificial tanning agent to the skin. The article includes an adhesive matrix disposed between at least two layers that are permanently...
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6719989 |
Sustained release drug carrier, and method of manufacturing sustained release drug carrier
A sustained release drug carrier comprises a ceramic composite which is formed by bonding a plurality of ceramic bodies together, and drugs impregnated into the ceramic composite. A method of...
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6720007 |
Polymeric microspheres
The invention features core-shell microsphere compositions, hollow polymeric microspheres, and methods for making the microspheres. The microspheres are characterized as having a polymeric shell...
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6720073 |
Material enhancement to maintain high absorbent capacity under high loads following rigorous process conditions
An absorbent composite that can handle complex fluids and maintain high absorbent capacity under high loads even after the material has been subjected to rigorous processing conditions. The...
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6719993 |
Calcium phosphate cements prepared from silicate solutions
Methods are provide for producing flowable compositions, e.g. pastes, that set into calcium phosphate products. In the subject methods, dry reactants that include a calcium source and a phosphate...
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6720006 |
Anti-microbial body care product
An anti-microbial body care product comprising in the part contacting the human or animal skin and/or mucosa and organic matrix containing homogeneously dispersed particles of a metallic silver...
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6719996 |
Galenic composition for low bioavailability medicaments
A pharmaceutical composition for oral administration of an active compound having a bioavailability of 20% or less. The composition comprises, based on its total weight, from 0.01% to about 15%...
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6716458 |
Nutritional supplement
The is invention is directed to a composition useful for assisting in supplying a warm-blooded animal with many of its nutritional needs. More specifically, this invention is directed to a...
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6713076 |
Methods for removing a contaminant by a polyoxometalate-modified fabric or a polyoxometalate-modified cellulosic fiber and fabrics thereof
The invention relates to a method for removing a contaminant from a gas phase or a liquid phase by contacting an article composed of (1) a fabric or cellulosic fiber and (2) a polyoxometalate,...
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6713081 |
Ocular therapeutic agent delivery devices and methods for making and using such devices
Ocular implant devices for the delivery of a therapeutic agent to an eye in a controlled and sustained manner. Dual mode and single mode drug delivery devices are illustrated and described....
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6709669 |
Fast-dispersing dosage forms containing fish gelatin
The invention disclosed herein relates to a pharmaceutical composition comprising a carrier and an active ingredient, wherein the carrier is fish gelatin and the composition is a fast-dispersing...
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6706778 |
Process for the production of molded particles for microbial cell-immobilization
This invention provides a process for the production of molded particles for microbial cell-immobilization which is characterized in that: an aqueous liquid composition which comprises: (a) an...
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