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6080420 |
Fibres of cospun alginates
Fibres which are useful in wound dressings comprising an alginate co-spun with at least one water soluble organic polymeric species (other than an alginate). Examples of such fibers comprise...
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6077916 |
Biodegradable mixtures of polyphoshazene and other polymers
Biodegradable polymeric compositions are provided, wherein biodegradable polyphosphazenes are combined with at least one other polymer, either in the form of a blend, a semi-interpenetrating...
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6074674 |
Formulations for sustained-release of topical anesthetics and methods of making and using same
The present invention provides, inter alia, formulations useful to ameliorate symptoms associated with mucosal abrasions, specifically those due to dental orthodontic brackets; oral surgery;...
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6068859 |
Controlled-release dosage forms of Azithromycin
A controlled-release dosage form of azithromycin having an improved side effect profile; a process for preparing the dosage form; and a method of treating a microbial infection, comprising...
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6066337 |
Method for producing a rapidly dissolving dosage form
A particulate support matrix, and a dosage form made therefrom, and processes for making such support matrices and dosage forms, which disintegrate or dissolve in a matter of just a few seconds...
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6066339 |
Oral morphine multiparticulate formulation
An oral morphine multiparticulate formulation for once-daily administration to a patient, comprising sustained release particles each having a core containing water soluble morphine and an osmotic...
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6060085 |
Compositions and methods for topical application of therapeutic agents
The present invention generally relates to pharmaceutical compositions that enable control of drug delivery properties and the development of optimal drug delivery strategies customized for...
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6056976 |
Elastomer, its preparation and use
The invention relates to a siloxane-based elastomer intended for controlling the permeation of drugs, wherein the elastomer includes 3,3,3,-trifluoropropyl groups attached to the Si-atoms of the...
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6051425 |
Method for producing tissue formation and tissue culture kit
A matrix for tissue culture comprising two kinds of sponges having at least one different physical property and/or at least one different chemical property; a method for culturing tissue using said...
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6048541 |
Fast-dissolving comestible units formed under high-speed/high-pressure conditions
The invention relates to compositions useful for making tablets which can be formed using conventional tableting machines and which disintegrate rapidly in the mouth with optional chewing. The...
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6048546 |
Immobilized lipid-bilayer materials
A method for preparing encapsulated lipid-bilayer materials in a silica matrix comprising preparing a silica sol, mixing a lipid-bilayer material in the silica sol and allowing the mixture to gel...
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6045823 |
Process for producing solid anhydrous composition, and pharmaceutical and cosmetic products comprising same
Anhydrous cosmetic stick formulations such as lip balms, lipsticks, and underarm deodorant or antiperspirant sticks, comprising an organic matrix having particles homogeneously dispersed therein,...
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6045827 |
Treatment of equine laminitis
Compositions and methods of the topical treatment of equine laminitis are disclosed. In particular, combinations of a fast acting nitric oxide (NO) donor, a sustained acting NO donor and an NSAID...
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6042817 |
Polyurethane foam lithium hypochlorite composition
A chemical composition comprising a polyester based urethane foam material impregnated or coated with an aqueous lithium hypochlorite solution, and optionally containing a quaternary ammonium...
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6036977 |
Drug preparations for treating sexual dysfunction
Topical gelled compositions comprising a drug for treating sexual dysfunction dispersed within a polymer matrix and methods and treatments using said compositions.
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6037374 |
Composition and method for the control of parasitic mites in honey bees
Gel compositions of formic acid and a gelling agent such as fumed silica or polyacrylic acid have been prepared for controlling parasitic mites of honey bees. The gels provide slow-release...
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6033684 |
Compositions and methods for wound management
A wound dressing composition and a method of using that composition to enhance the natural process of topical wound healing. The composition comprises at least one adhesive ingredient that adheres...
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6024968 |
Intersorption composition and method
Active ingredients are solubilized or dispersed in a matrix which also contains dispersants. When this composition is applied to a permeable substrate, the matrix and dispersants associate with the...
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6022563 |
Phenylbutazone carrier formulation
A powdered carrier formulation for delivery of phenylbutazone to animals contains phenylbutazone in combination with a flavoring agent and an anticaking agent.
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6022554 |
Polymeric microporous film coated subcutaneous implant
This invention relates to coating formulations for coating sustained-release drug implants. The coating formulations are capable of formulations are capable of forming a porous film coat over a...
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6020200 |
Encapsulation compositions and methods
The present invention generally relates to novel encapsulation compositions and methods. In particular, the invention relates to stabilized microcapsule compositions which comprise a layer of a...
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6010714 |
Non-thermogenic heat dissipating biomedical adhesive compositions
A biocompatible monomer composition includes at least one monomer, which forms a medically acceptable polymer, and an effective amount of at least one heat dissipating agent sufficient to reduce...
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6004576 |
Granular plasma protein supplement with increased bio-efficacy
A feed supplement is disclosed comprising animal plasma purified from animal blood which is granulated. Animals fed this supplement experienced a significantly higher average daily gain and...
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6001384 |
Method for fighting against myiasis affecting cattle and sheep populations and compositions for implementing same
Process for controlling myiasis in cattle and sheep livestock and compositions for carrying out this process. Composition for topical or parenteral use for controlling myiasis in cattle and sheep,...
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6001346 |
Aqueous emulsion comprising biodegradable carrier for insect pheromones and methods for controlled release thereof
A sprayable or solid biodegradable wax carrier for insect pheromones and a method for constant release rate of the pheromone from the biodegradable wax. A composition comprising a pheromone and...
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6001338 |
Cosmetic use of natural microfibrils and a film-forming polymer as a composite coating agent for hair, eyelashes, eyebrows and nails
The present invention relates to the use of a polymer which forms a film in aqueous solution or in aqueous dispersion and of an aqueous suspension of microfibrils of natural origin in the form of...
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6001380 |
Medicated applicator sheet for topical drug delivery
The present invention provides a method for applying a plurality, preferably two, of dermatological agents to the skin from a single dispensing and applicator sheet comprising a plurality of...
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5997903 |
Oral-administration forms of a medicament containing pantoprazol
The invention relates to oral presentation forms for pantoprazole, which consist of a core, an intermediate layer and an outer layer which is resistant to gastric juice.
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5997901 |
Method of manufacturing scented molded products
A scented molded product, e.g. an effervescent bath tablet or an air freshener, is made by mixing sodium bicarbonate, water and fragrance oils to form a first mixture, adding to this first mixture...
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5989586 |
Two-phase matrix for sustained release drug delivery device
A two-phase hydrophilic drug-containing matrix for use in transdermal drug delivery patches in which one phase is a continuous hydrophobic polymer phase which optionally includes a hydrophobic...
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5985326 |
Method of producing a solid dispersion of a poorly water soluble drug
Solid dispersions of poorly soluble drugs, such as (6R,12aR)-2,3,6,7,12,12a-hexahydro-2-methyl-6-(3,4-methylene
dioxyphenyl)-p yrazino[2',1':6,1]pyrido[3,4-b]indole-1,4-dione and...
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5980945 |
Sustained release drug formulations
A sustained release drug formulation including: a drug; a biodegradable polymer which is insoluble in water; and an oil vehicle in which both the drug and the polymer are dissolved. The oil vehicle...
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5980942 |
Zero-order sustained release matrix tablet formulations of carbamazepine
A zero-order sustained-release delivery system for delivery of carbamazepine. A matrix tablet formulations of carbamazepine comprising hydrophilic polymer gel which inhibits transformation of...
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5980946 |
Collagen formulations
Disclosed are proteinaceous compositions comprising collagen and an effective amount of a compatible cytotoxic drug which compositions are characterized by having a single collagen transition...
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5976577 |
Process for preparing fast dispersing solid oral dosage form
Process is provided for preparing an oral solid rapidly disintegrating freeze-dried dosage form of a pharmaceutically active substance having an unacceptable taste, wherein prior to freeze drying,...
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5976566 |
Non-steroidal antiinflammtory drug formulations for topical application to the skin
Topical alcoholic or aqueous alcoholic gels containing ibuprofen or other NSAIDs, such as, naproxen, in substantially neutral salt form, have enhanced penetration through skin and may provide rapid...
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5977313 |
Platelet substitutes and conjugation methods suitable for their preparation
Platelet substitutes, comprising fibrinogen, or analogous products useful in therapy, which further comprise an insoluble carrier to which is bound an essentially non-degraded active protein...
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5972387 |
Modified hydrolyzed vegetable protein microspheres and methods for preparation and use thereof
Modified hydrolyzed vegetable protein microspheres and methods for their preparation and use as oral delivery systems for pharmaceutical agents are described.
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5968794 |
Biodegradable particulate vector for transporting molecules having biological activity
A biodegradable particulate vector for transporting biologically active molecules is prepared containing a nucleus formed of a cross-linked polysaccharide or oligosaccharide matrix having grafted...
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5968253 |
Calcium phosphate cements comprising antimicrobial agents
A flowable, paste-like composition capable of setting in a clinically relevant period of time into an antimicrobial agent loaded apatitic product having sufficient compressive strength to serve as...
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5965163 |
Substained release compositions and a method of preparing pharmaceutical compositions
A process for the manufacture of particles comprises mechanically working a mixture of a drug and a hydrophobic and/or hydrophilic fusible carrier in a high speed mixture so as to form...
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5965162 |
Process for forming chewable quickly dispersing multi-vitamin preparation and product therefrom
A composition and method for preparing multi-vitamin comestible units which disperse quickly in the mouth, especially when chewed, includes initiating crystallization of shearform matrix with...
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5965161 |
Extruded multi-particulates
A unit dose sustained-release oral dosage form containing a plurality of melt-extruded particles, each consisting essentially of a therapeutically active agent, one or more retardants, and an...
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5961967 |
Multiphase candle containing locally enriched regions of deliverable actives
A candle is provided for delivery of an active ingredient comprising a multiphase construction of a continuous first matrix and a second matrix dispersed therein. The first matrix comprises a...
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5962028 |
Carbonated hydroxyapatite compositions and uses
Carbonated hydroxyapatite compositions and their preparation are described. The compositions are biologically resorbable and are prepared as flowable masses which can be administered by syringe to...
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5961990 |
Cosmetic particulate gel delivery system and method of preparing complex gel particles
A protective cosmetic particulate gel delivery system for a topically applied active agent employs an agar gel and a restraining polymer to retain the actve agent in the gel. The particles have an...
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5958979 |
Stabilized medicaments containing thyroid hormones
The present invention relates to stabilized medicaments containing thyroid hormone the stabilizing component of which is sodium thiosulfate in a mass ratio of thyroid hormone to sodium thiosulfate...
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5958427 |
Nitric oxide donor compounds and pharmaceutical compositions for pulmonary hypertension and other indications
The invention is directed to nitric oxide (NO) donor compounds and to pharmaceutical compositions containing such nitric oxide (NO) donor compounds, for delivering NO to the apical surface of a...
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5955094 |
Intercalates and exfoliates formed with organic pesticides compounds and compositions containing the same
Intercalates formed by contacting an activated layered material, e.g., an activated phyllosilicate, with an intercalant pesticide to intercalate an intercalant pesticide between adjacent platelets...
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5952006 |
Drug preparations for treating impotency
Topical gelled compositions comprising a drug for treating impotency dispersed within a polymer matrix and treatments using the complex.
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