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6110500 |
Coated tablet with long term parabolic and zero-order release kinetics
A tablet for the controlled release of an active pharmaceutical ingredient. The tablet comprises a core having a donut-like configuration with a cylindrical hole extending through the center of the...
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6106863 |
Sustained-release metal valproate tablets
The present invention provides a sustained-release metal valproate tablet which is comparatively compact and is not influenced by a meal, the sustained-release metal valproate comprising a core...
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6096341 |
Delayed release tablet of bupropion hydrochloride
The invention provides a controlled release tablet, free of stabilizer and free of pore-forming agent comprising: (i) a core consisting essentially of bupropion hydrochloride, a binder and a...
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6090412 |
H.sub.2 -Receptor antagonist and antacid composition
A solid pharmaceutical composition for oral administration comprising a histamine H 2 -receptor antagonist, a low neutralizing capacity antacid, and a high neutralizing capacity antacid coated...
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6066336 |
Cholesterol-lowering tablets
An improved cholesterol-lowering tablet is manufactured by blending tablet grade cholestyramine with an appropriate amount of lubricant and directly compressing into elongated tablets having a...
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6066339 |
Oral morphine multiparticulate formulation
An oral morphine multiparticulate formulation for once-daily administration to a patient, comprising sustained release particles each having a core containing water soluble morphine and an osmotic...
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6051255 |
Polymer coated tablet comprising amoxycillin and clavulanate
The present invention is to a tablet formulation, being a medicament for oral administration for the treatment of bacterial infections, the tablet comprising a compacted mixture of 750-950 mg of...
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6036973 |
Therapy for neurological diseases
A dosage form is disclosed for administering 10 ng to 1200 mg tacrine to a patient in need of tacrine therapy.
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6033686 |
Controlled release tablet of bupropion hydrochloride
The invention provides a controlled release tablet, free of stabilizer and free of pore-forming agent comprising: (i) a core consisting essentially of bupropion hydrochloride, a binder and a...
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6027748 |
Pharmaceutical tablet, completely coated, for controlled release of active principles that present problems of bio-availability linked to gastro-intestinal absorption
Described herein is a particular type of pharmaceutical tablet, for oral use, which is formed by one or more layers, and is specifically designed for controlled release of active principles that...
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6025391 |
Enteric-coated pharmaceutical compositions of mycophenolate
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6001391 |
Process for producing solid drug forms having at least two phases
A process for producing solid combination tablets which have at least two phases comprises molding a melt of a polymeric binder with or without at least one active ingredient, there being at least...
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5997903 |
Oral-administration forms of a medicament containing pantoprazol
The invention relates to oral presentation forms for pantoprazole, which consist of a core, an intermediate layer and an outer layer which is resistant to gastric juice.
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5997905 |
Preparation of pharmaceutically active particles
The present invention provides a core of predominately microcrystalline cellulose, on which an active drug is layered onto the core via solution coating. The coated particles have a narrower...
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5968552 |
Diltiazem hydrochloride formulation
The invention relates to a pharmaceutical formulation comprising diltiazem hydrochloride. The formulation is in the form of a mixture of beads blended so as to provide a dissolution profile that...
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5962024 |
Peroral composition for controlled release in the lower gastrointestinal tract
The invention relates to a peroral composition providing controlled release of a drug, the composition comprising a) a core comprising the drug and a drug release controlling agent and b) an...
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5958459 |
Opioid formulations having extended controlled released
Solid controlled-release oral dosage forms comprising a therapeutically effective amount of an opioid analgesic or a salt thereof which provide an extended duration of pain relief of about 24...
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5914132 |
Pharmaceutical dosage form with multiple enteric polymer coatings for colonic delivery
The present invention relates to a pharmaceutical composition in a unit dosage form for peroral administration in a human or lower animal, having a gastrointestinal tract comprising a small...
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5912013 |
Advanced drug delivery system and method of treating psychiatric, neurological and other disorders with carbamazepine
The present invention relates to a composition and method of treating a patient by administering carbamazepine in a pharmaceutical dosage form capable of maintaining the patient's blood...
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5908638 |
Pharmaceutical compositions of conjugated estrogens and methods for their use
This invention relates to novel pharmaceutical compositions and methods for their preparation containing conjugated estrogens for the treatment of peri-menopausal, menopausal and post-menopausal...
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5861173 |
Long-lasting release nifedipine preparation
This invention provides a long-lasting release solid nifedipine preparation which exhibits clinically sufficient effect when administered once per day. A press coated tablet whose core and shell...
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5849327 |
Delivery of drugs to the lower gastrointestinal tract
Diseases of the colon are treated by oral ingestion of a unit dosage form containing a plurality of porous microscopic beads, the pores containing an active agent or drug and plugged with a...
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5837291 |
Enteric preparation coated with a non-solvent enteric coating agent using a liquid plasticizer
An enteric preparation prepared by coating a solid dosage form with a fine powder enteric coating agent while spraying a liquid plasticizer.
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5837285 |
Fast soluble tablet
The object of the present invention is to provide a tablet that dissolves rapidly in the oral cavity (fast soluble tablets) that can be produced by a simple method without special preparation...
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5830503 |
Enteric coated diltiazem once-a-day formulation
A once-a-day diltiazem dosage form which comprises: (a) a core element which is a compressed tablet which contains a therapeutic dose of diltiazem and an amount of a solubility modulating substance...
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5814339 |
Film coated tablet of paracetamol and domperidone
The present invention is concerned with a film coated tablet comprising as active ingredients the analgesic agent paracetamol and the antiemetic agent domperidone, and with a process of preparing...
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5814336 |
Pharmaceutical dosage form for colonic delivery
The present invention relates to a pharmaceutical composition in a unit dosage form for peroral administration in a human or lower animal, having a gastrointestinal tract comprising a small...
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5807576 |
Rapidly dissolving tablet
The present invention comprises a tablet, and method for making such, which disintegrates or dissolves in a matter of just a few seconds once placed into the oral cavity. Generally, the method of...
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5807579 |
Pseudoephedrine combination pharmaceutical compositions
A pharmaceutical tablet composition for oral administration containing pseudoephedrine pellets admixed with a tablet mixture containing a second active drug substance, either alone or in...
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5798120 |
Enteric granule-containing tablets
The present invention relates to enteric granule-containing tablets which are prepared by tabletting a mixture of enteric granules containing an active agent, with one or a combination of 2 or more...
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5788987 |
Methods for treating early morning pathologies
The present invention provides methods of treating early morning pathologies using a time-specific controlled release dosage formulation which is administered prior to sleep, and which permits or...
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5783212 |
Controlled release drug delivery system
The present invention pertains to a controlled release pharmaceutical tablet having at least three layers, two barrier layers and one drug layer. The two barrier layers erode more quickly than the...
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5783193 |
Oral administration of therapeutic proteins for treatment of autoimmune disease, transplant rejection and infectious disease
An orally administrable therapeutic protein is provided by combining the therapeutic protein with a stabilizing agent in an aqueous solution. The solution is coated onto nonpareils and...
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5780057 |
Pharmaceutical tablet characterized by a showing high volume increase when coming into contact with biological fluids
A description is given of a pharmaceutical form for oral administration consisting of a two- or three-layers tablet, wherein at least one layer can rapidly swell by contact with biological and/or...
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5762963 |
Method and compositions for controlling oral and pharyngeal pain using capsaicinoids
Methods and compositions are provided for the oral delivery of temporally increasing concentrations of capsaicin, its derivatives, and analogs (collectively, "capsaicinoids"), to provide oral or...
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5753265 |
Multiple unit pharmaceutical preparation
A new pharmaceutical multiple unit tableted dosage form containing as active ingredient an acid labile H + K + -ATPase inhibitor or an alkaline salt thereof or one of its single enantiomers or an...
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5734006 |
N-vinyl lactam copolymer containing tablets of low friability and high rate of dissolution
This invention relates to a coprecipitated binder composition used for the compression of pharmaceutically and agriculturally active components to provide a non-friable pill or tablet of increased...
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5731002 |
Veterinary composition
A stable, oral pharmaceutical composition comprising a proton pump inhibitor and a gelling agent designed for the treatment of gastric acid related diseases in animals, the process for preparation...
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5725880 |
Pharmaceutical preparation controlled to release medicinal active ingredient at targeted site in intestinal tract
A pharmaceutical preparation for oral administration which is controlled to release a medicinal active ingredient at a targeted site in the intestinal tract comprising (a) a core containing a...
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5723151 |
Cellulose acetate phthalate enteric coating compositions
Provided are enteric coating compositions which utilize a low viscosity cellulose acetate phthalate polymer as a film former. The cellulose acetate phthalates have an inherent viscosity of about...
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5721026 |
Aqueous silicone/(CO) polymer dispersions crosslinkable into elastomeric state
Aqueous silicone dispersions crosslinkable into elastomeric state on removal of water therefrom under ambient conditions, well adapted, e.g., for the production of elastomeric silicone seals in the...
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5705189 |
Thermoplastic material for drug coatings which dissolve in intestinal juices
Thermoplastic materials which comprise a copolymer of (A) 16 to 40 wt % of acrylic and/or methacrylic acid; (B) 30 to 80 wt % of methyl acrylate; and (C) 0 to 40 wt % of another alkyl...
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5693340 |
Delayed-release form for pharmaceutical active compounds
A novel delayed-release form for pharmaceutical active compounds, characterized by a core containing the active compound and a diffusion-inhibiting, adhesive coating layer having a thickness in the...
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5690960 |
Pharmaceutical formulation of omeprazole
A new oral pharmaceutical formulation containing a novel physical form of a magnesium salt of omeprazole, a method for the manufacture of such a formulation, and the use of such a formulation in...
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5683719 |
Controlled release compositions
A controlled release composition comprising an extruded core of active material and excipients, said core being coated in a water insoluble coating. Preferably the core comprises a pharmaceutically...
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5684121 |
N-vinyl lactam polymer containing tablets of low friability and high rate of dissolution
This invention relates to a coprecipitated binder composition used for the compression of pharmaceutically and agriculturally active components to provide a non-friable, readily soluble or...
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5667976 |
Solid supports for nucleic acid hybridization assays
Compositions and methods for covalently immobilizing an oligonucleotide onto a polymer-coated solid support or similar structure are provided. Specifically, the polymer-coated support, such as a...
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5662936 |
Sugar-coated pharmaceutical dosage unit
The invention relates to sugar-coated dosage units comprising a steroid having two hydrogen atoms at position 3 of the steroid skeleton, such as desogestrel, allylestrenol, ethylestrenol, or...
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5656296 |
Dual control sustained release drug delivery systems and methods for preparing same
The present invention pertains to a dual control sustained release drug delivery system which comprises a core and a porous coating layer over the core, wherein the coated core comprises (A) a core...
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5654004 |
Oral pharmaceutical preparation releasable in the lower digestive tract
An oral pharmaceutical preparation releasable in the lower digestive tract, characterized by having a double-coated structure wherein a solid drug having a core containing an active ingredient is...
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