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6110500 Coated tablet with long term parabolic and zero-order release kinetics  
A tablet for the controlled release of an active pharmaceutical ingredient. The tablet comprises a core having a donut-like configuration with a cylindrical hole extending through the center of the...
6106863 Sustained-release metal valproate tablets  
The present invention provides a sustained-release metal valproate tablet which is comparatively compact and is not influenced by a meal, the sustained-release metal valproate comprising a core...
6096341 Delayed release tablet of bupropion hydrochloride  
The invention provides a controlled release tablet, free of stabilizer and free of pore-forming agent comprising: (i) a core consisting essentially of bupropion hydrochloride, a binder and a...
6090412 H.sub.2 -Receptor antagonist and antacid composition  
A solid pharmaceutical composition for oral administration comprising a histamine H 2 -receptor antagonist, a low neutralizing capacity antacid, and a high neutralizing capacity antacid coated...
6066336 Cholesterol-lowering tablets  
An improved cholesterol-lowering tablet is manufactured by blending tablet grade cholestyramine with an appropriate amount of lubricant and directly compressing into elongated tablets having a...
6066339 Oral morphine multiparticulate formulation  
An oral morphine multiparticulate formulation for once-daily administration to a patient, comprising sustained release particles each having a core containing water soluble morphine and an osmotic...
6051255 Polymer coated tablet comprising amoxycillin and clavulanate  
The present invention is to a tablet formulation, being a medicament for oral administration for the treatment of bacterial infections, the tablet comprising a compacted mixture of 750-950 mg of...
6036973 Therapy for neurological diseases  
A dosage form is disclosed for administering 10 ng to 1200 mg tacrine to a patient in need of tacrine therapy.
6033686 Controlled release tablet of bupropion hydrochloride  
The invention provides a controlled release tablet, free of stabilizer and free of pore-forming agent comprising: (i) a core consisting essentially of bupropion hydrochloride, a binder and a...
6027748 Pharmaceutical tablet, completely coated, for controlled release of active principles that present problems of bio-availability linked to gastro-intestinal absorption  
Described herein is a particular type of pharmaceutical tablet, for oral use, which is formed by one or more layers, and is specifically designed for controlled release of active principles that...
6025391 Enteric-coated pharmaceutical compositions of mycophenolate  
6001391 Process for producing solid drug forms having at least two phases  
A process for producing solid combination tablets which have at least two phases comprises molding a melt of a polymeric binder with or without at least one active ingredient, there being at least...
5997903 Oral-administration forms of a medicament containing pantoprazol  
The invention relates to oral presentation forms for pantoprazole, which consist of a core, an intermediate layer and an outer layer which is resistant to gastric juice.
5997905 Preparation of pharmaceutically active particles  
The present invention provides a core of predominately microcrystalline cellulose, on which an active drug is layered onto the core via solution coating. The coated particles have a narrower...
5968552 Diltiazem hydrochloride formulation  
The invention relates to a pharmaceutical formulation comprising diltiazem hydrochloride. The formulation is in the form of a mixture of beads blended so as to provide a dissolution profile that...
5962024 Peroral composition for controlled release in the lower gastrointestinal tract  
The invention relates to a peroral composition providing controlled release of a drug, the composition comprising a) a core comprising the drug and a drug release controlling agent and b) an...
5958459 Opioid formulations having extended controlled released  
Solid controlled-release oral dosage forms comprising a therapeutically effective amount of an opioid analgesic or a salt thereof which provide an extended duration of pain relief of about 24...
5914132 Pharmaceutical dosage form with multiple enteric polymer coatings for colonic delivery  
The present invention relates to a pharmaceutical composition in a unit dosage form for peroral administration in a human or lower animal, having a gastrointestinal tract comprising a small...
5912013 Advanced drug delivery system and method of treating psychiatric, neurological and other disorders with carbamazepine  
The present invention relates to a composition and method of treating a patient by administering carbamazepine in a pharmaceutical dosage form capable of maintaining the patient's blood...
5908638 Pharmaceutical compositions of conjugated estrogens and methods for their use  
This invention relates to novel pharmaceutical compositions and methods for their preparation containing conjugated estrogens for the treatment of peri-menopausal, menopausal and post-menopausal...
5861173 Long-lasting release nifedipine preparation  
This invention provides a long-lasting release solid nifedipine preparation which exhibits clinically sufficient effect when administered once per day. A press coated tablet whose core and shell...
5849327 Delivery of drugs to the lower gastrointestinal tract  
Diseases of the colon are treated by oral ingestion of a unit dosage form containing a plurality of porous microscopic beads, the pores containing an active agent or drug and plugged with a...
5837291 Enteric preparation coated with a non-solvent enteric coating agent using a liquid plasticizer  
An enteric preparation prepared by coating a solid dosage form with a fine powder enteric coating agent while spraying a liquid plasticizer.
5837285 Fast soluble tablet  
The object of the present invention is to provide a tablet that dissolves rapidly in the oral cavity (fast soluble tablets) that can be produced by a simple method without special preparation...
5830503 Enteric coated diltiazem once-a-day formulation  
A once-a-day diltiazem dosage form which comprises: (a) a core element which is a compressed tablet which contains a therapeutic dose of diltiazem and an amount of a solubility modulating substance...
5814339 Film coated tablet of paracetamol and domperidone  
The present invention is concerned with a film coated tablet comprising as active ingredients the analgesic agent paracetamol and the antiemetic agent domperidone, and with a process of preparing...
5814336 Pharmaceutical dosage form for colonic delivery  
The present invention relates to a pharmaceutical composition in a unit dosage form for peroral administration in a human or lower animal, having a gastrointestinal tract comprising a small...
5807576 Rapidly dissolving tablet  
The present invention comprises a tablet, and method for making such, which disintegrates or dissolves in a matter of just a few seconds once placed into the oral cavity. Generally, the method of...
5807579 Pseudoephedrine combination pharmaceutical compositions  
A pharmaceutical tablet composition for oral administration containing pseudoephedrine pellets admixed with a tablet mixture containing a second active drug substance, either alone or in...
5798120 Enteric granule-containing tablets  
The present invention relates to enteric granule-containing tablets which are prepared by tabletting a mixture of enteric granules containing an active agent, with one or a combination of 2 or more...
5788987 Methods for treating early morning pathologies  
The present invention provides methods of treating early morning pathologies using a time-specific controlled release dosage formulation which is administered prior to sleep, and which permits or...
5783212 Controlled release drug delivery system  
The present invention pertains to a controlled release pharmaceutical tablet having at least three layers, two barrier layers and one drug layer. The two barrier layers erode more quickly than the...
5783193 Oral administration of therapeutic proteins for treatment of autoimmune disease, transplant rejection and infectious disease  
An orally administrable therapeutic protein is provided by combining the therapeutic protein with a stabilizing agent in an aqueous solution. The solution is coated onto nonpareils and...
5780057 Pharmaceutical tablet characterized by a showing high volume increase when coming into contact with biological fluids  
A description is given of a pharmaceutical form for oral administration consisting of a two- or three-layers tablet, wherein at least one layer can rapidly swell by contact with biological and/or...
5762963 Method and compositions for controlling oral and pharyngeal pain using capsaicinoids  
Methods and compositions are provided for the oral delivery of temporally increasing concentrations of capsaicin, its derivatives, and analogs (collectively, "capsaicinoids"), to provide oral or...
5753265 Multiple unit pharmaceutical preparation  
A new pharmaceutical multiple unit tableted dosage form containing as active ingredient an acid labile H + K + -ATPase inhibitor or an alkaline salt thereof or one of its single enantiomers or an...
5734006 N-vinyl lactam copolymer containing tablets of low friability and high rate of dissolution  
This invention relates to a coprecipitated binder composition used for the compression of pharmaceutically and agriculturally active components to provide a non-friable pill or tablet of increased...
5731002 Veterinary composition  
A stable, oral pharmaceutical composition comprising a proton pump inhibitor and a gelling agent designed for the treatment of gastric acid related diseases in animals, the process for preparation...
5725880 Pharmaceutical preparation controlled to release medicinal active ingredient at targeted site in intestinal tract  
A pharmaceutical preparation for oral administration which is controlled to release a medicinal active ingredient at a targeted site in the intestinal tract comprising (a) a core containing a...
5723151 Cellulose acetate phthalate enteric coating compositions  
Provided are enteric coating compositions which utilize a low viscosity cellulose acetate phthalate polymer as a film former. The cellulose acetate phthalates have an inherent viscosity of about...
5721026 Aqueous silicone/(CO) polymer dispersions crosslinkable into elastomeric state  
Aqueous silicone dispersions crosslinkable into elastomeric state on removal of water therefrom under ambient conditions, well adapted, e.g., for the production of elastomeric silicone seals in the...
5705189 Thermoplastic material for drug coatings which dissolve in intestinal juices  
Thermoplastic materials which comprise a copolymer of (A) 16 to 40 wt % of acrylic and/or methacrylic acid; (B) 30 to 80 wt % of methyl acrylate; and (C) 0 to 40 wt % of another alkyl...
5693340 Delayed-release form for pharmaceutical active compounds  
A novel delayed-release form for pharmaceutical active compounds, characterized by a core containing the active compound and a diffusion-inhibiting, adhesive coating layer having a thickness in the...
5690960 Pharmaceutical formulation of omeprazole  
A new oral pharmaceutical formulation containing a novel physical form of a magnesium salt of omeprazole, a method for the manufacture of such a formulation, and the use of such a formulation in...
5683719 Controlled release compositions  
A controlled release composition comprising an extruded core of active material and excipients, said core being coated in a water insoluble coating. Preferably the core comprises a pharmaceutically...
5684121 N-vinyl lactam polymer containing tablets of low friability and high rate of dissolution  
This invention relates to a coprecipitated binder composition used for the compression of pharmaceutically and agriculturally active components to provide a non-friable, readily soluble or...
5667976 Solid supports for nucleic acid hybridization assays  
Compositions and methods for covalently immobilizing an oligonucleotide onto a polymer-coated solid support or similar structure are provided. Specifically, the polymer-coated support, such as a...
5662936 Sugar-coated pharmaceutical dosage unit  
The invention relates to sugar-coated dosage units comprising a steroid having two hydrogen atoms at position 3 of the steroid skeleton, such as desogestrel, allylestrenol, ethylestrenol, or...
5656296 Dual control sustained release drug delivery systems and methods for preparing same  
The present invention pertains to a dual control sustained release drug delivery system which comprises a core and a porous coating layer over the core, wherein the coated core comprises (A) a core...
5654004 Oral pharmaceutical preparation releasable in the lower digestive tract  
An oral pharmaceutical preparation releasable in the lower digestive tract, characterized by having a double-coated structure wherein a solid drug having a core containing an active ingredient is...