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5840332 |
Gastrointestinal drug delivery system
A gastrointestinal delivery system is provided. The system comprises a drug in combination with a core material, the core being surrounded by a water-insoluble or relatively water-insoluble coating...
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5837291 |
Enteric preparation coated with a non-solvent enteric coating agent using a liquid plasticizer
An enteric preparation prepared by coating a solid dosage form with a fine powder enteric coating agent while spraying a liquid plasticizer.
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5837285 |
Fast soluble tablet
The object of the present invention is to provide a tablet that dissolves rapidly in the oral cavity (fast soluble tablets) that can be produced by a simple method without special preparation...
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5830503 |
Enteric coated diltiazem once-a-day formulation
A once-a-day diltiazem dosage form which comprises: (a) a core element which is a compressed tablet which contains a therapeutic dose of diltiazem and an amount of a solubility modulating substance...
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5814339 |
Film coated tablet of paracetamol and domperidone
The present invention is concerned with a film coated tablet comprising as active ingredients the analgesic agent paracetamol and the antiemetic agent domperidone, and with a process of preparing...
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5814336 |
Pharmaceutical dosage form for colonic delivery
The present invention relates to a pharmaceutical composition in a unit dosage form for peroral administration in a human or lower animal, having a gastrointestinal tract comprising a small...
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5807580 |
Film coated tablet compositions having enhanced disintegration characteristics
A pharmaceutical composition for oral administration comprising a film coated tablet exhibiting enhanced disintegration characteristics, said film coating comprising a hydrophilic film forming...
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5800836 |
Pelletized pharmaceutical composition
A pelletized sustained release pharmaceutical composition including a core element including approximately 0.1 to 95% by weight, based on the total weight of the core element, of an active...
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5792471 |
Dispensing devices powered by hydrogel
This invention relates to devices useful for the controlled delivery of one or more beneficial agents to an environment of use. More specifically, this invention concerns such devices which are...
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5788987 |
Methods for treating early morning pathologies
The present invention provides methods of treating early morning pathologies using a time-specific controlled release dosage formulation which is administered prior to sleep, and which permits or...
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5780055 |
Cushioning beads and tablet comprising the same capable of forming a suspension
Cushioning beads comprising microcrystalline cellulose and a disintegrant (preferably croscarmellose sodium) are disclosed. The cushioning beads are prepared by extrusion-spheronization, followed...
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5776501 |
Coating base for solid enteric pharmaceutical preparations
The present invention provides a base for coating a solid enteric pharmaceutical preparation whose dissolution pH ranges from 3 to 4. The coating base is a cellulose acetate maleate which is...
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5770227 |
Progesterone replacement therapy
A hormone replacement composition, a hormone replacement dosage form, and a method of hormone replacement are disclosed and indicated for the management of hormone replacement therapy.
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5766619 |
Pharmaceutical dosage form for ocular administration and preparation process
An insoluble pharmaceutical dosage form for ocular administration including a matrix including at least one polymer and at least one active ingredient and a first layer of glycerides distributed at...
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5759580 |
Compositions containing micronized nebivolol
The present invention relates to pharmaceutical compositions containing as active ingredient micronized nebivolol of formula (I) and ways of preparing said compositions. ##STR1##
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5753265 |
Multiple unit pharmaceutical preparation
A new pharmaceutical multiple unit tableted dosage form containing as active ingredient an acid labile H + K + -ATPase inhibitor or an alkaline salt thereof or one of its single enantiomers or an...
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5750145 |
Stable gelatin coated aspirin tablets
Gelatin coated pharmaceutical dosage units containing, for example, analgesic compounds, such as aspirin, stabilized with a proteolytic enzyme, such as pepsin, are described.
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5750148 |
Method for preparing solid enteric pharmaceutical preparation
A cellulosic enteric base is dissolved in an organic solvent capable of being admixed with water in any rate or a mixed solvent of the organic solvent and water to give a polymer solution, followed...
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5736159 |
Controlled release formulation for water insoluble drugs in which a passageway is formed in situ
A controlled release pharmaceutical tablet is disclosed which is based on: (a) a compressed core which contains: (i) a medicament; (ii) at least 23% to 55% by weight, based on the total...
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5731002 |
Veterinary composition
A stable, oral pharmaceutical composition comprising a proton pump inhibitor and a gelling agent designed for the treatment of gastric acid related diseases in animals, the process for preparation...
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5725880 |
Pharmaceutical preparation controlled to release medicinal active ingredient at targeted site in intestinal tract
A pharmaceutical preparation for oral administration which is controlled to release a medicinal active ingredient at a targeted site in the intestinal tract comprising (a) a core containing a...
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5723143 |
Solid mucoadhesive therapeutic or hygienic composition for application to the buccal or nasal mucous membrane
Solid mucoadhesive therapeutic or hygienic composition, for human or veterinary use, intended to be administered by application to the buccal or nasal mucous membrane, containing, in a mixture, 15...
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5723151 |
Cellulose acetate phthalate enteric coating compositions
Provided are enteric coating compositions which utilize a low viscosity cellulose acetate phthalate polymer as a film former. The cellulose acetate phthalates have an inherent viscosity of about...
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5721221 |
Lowering blood cholesterol levels using water soluble cellulose ethers
A method for reducing the cholesterol level in mammalian blood by administering a water soluble cellulose ether thereto. The cellulose ethers have a viscosity, measured as a 2% aqueous solution at...
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5698220 |
Asymmetric membranes in delivery devices
A device for controlled release of an active substance through one or more asymmetric membranes by diffusion and/or osmotic pumping.
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5698224 |
Tacrine therapy
A dosage form is disclosed for administering 10 ng to 1200 mg tacrine to a patient in need of tacrine therapy.
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5698226 |
Water-dispersible tablets
A water-dispersible tablet comprises an active compound such as acyclovir or lamotrigine and a dispersing agent. The dispersing agent is a swellable clay such as a smectite, e.g. Veegum F or...
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5695782 |
Double-layered oxcarbazepine tablets
The invention relates to color-stable tablets for the therapeutic drug oxcarbazepine, which tablets are provided with a hydrophilic, permeable layer containing white pigments and a hydrophilic,...
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5690960 |
Pharmaceutical formulation of omeprazole
A new oral pharmaceutical formulation containing a novel physical form of a magnesium salt of omeprazole, a method for the manufacture of such a formulation, and the use of such a formulation in...
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5686109 |
Antipyretic analgesic composition
This invention provides an antipyretic analgesic preparation having good antipyretic and analgesic effects with reduced adverse effects such as gastrointestinal disorders. The object is achieved by...
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5681582 |
Extended release, film-coated tablet of astemizole and pseudoephedrine
The present invention is concerned with an extended release, film coated tablet comprising as active ingredients the antihistaminic, antiallergic agent astemizole and the adrenergic, decongestant...
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5674495 |
Alginate-based vaccine compositions
A vaccine composition including an antigen dispersed in an alginate gel is described. The alginate gel is preferably in the form of discrete particles coated with a polymer. Vaccination of...
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5672360 |
Method of treating pain by administering 24 hour oral opioid formulations
Patients are treated with 24-hour oral sustained release opioid formulations which, upon administration, provide an initially rapid opioid absorption such that the minimum effective analgesic...
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5667573 |
Coating composition for preparing solid preparations and solid preparations
The present invention provides a sugar coating composition comprising erythritol, a water-soluble cellulose, and an aqueous medium; and a solid preparation comprising a center core of a medicine or...
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5654005 |
Controlled release formulation having a preformed passageway
A controlled release pharmaceutical tablet having at least one passageway, said tablet having: (a) a compressed core which comprises: (i) a medicament; (ii) an amount of a water soluble...
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5654004 |
Oral pharmaceutical preparation releasable in the lower digestive tract
An oral pharmaceutical preparation releasable in the lower digestive tract, characterized by having a double-coated structure wherein a solid drug having a core containing an active ingredient is...
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5650168 |
Tablet with improved bioavailability containing dichloromethylenediphosphonic acid as the active substance
The invention concerns tablets with improved bioavailability of the active substance dichloromethylenediphosphonic acid or of a physiologically tolerated salt thereof and with a content of...
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5641513 |
Tablet coating method
A method for coating pharmaceutical tablets is disclosed in which polymeric coating ingredients are combined with saccharides in a melt spinning operation to form composite particulates. The...
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5641516 |
Compositions which contain active substances and are in the form of solid particles
Compositions which contain active substances and are in the form of solid particles can be obtained by intimately mixing the active substance with a water-soluble melt composed of a) 10-90% by...
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5629017 |
Programmed release oral solid pharmaceutical dosage form
A programmed release pharmaceutical dosage form comprising a core, containing the active ingredient, coated by a hydrophobic layer is described. Such dosage forms release the active ingredient...
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5629003 |
Rapidly disintegrating sheet-like presentations of multiple dosage units
A presentation which, in the form of a film, permits the individual dosage of drugs, confectionary, other food, cosmetics and the like for oral application or intake. The presentation is...
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5626875 |
Stabilized galenic formulations comprising an acid labile benzimidazole compound and its preparation
New stable oral pharmaceutical formulations are prepared by covering an inert nucleus with a first layer containing an acid labile benzimidazole compound, a water soluble polymer and non-alkaline...
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5603953 |
Supported liquid membrane delivery devices
Supported liquid membrane delivery devices that release a beneficial agent to an aqueous environment following exposure to an environmental trigger. A microporous hydrophobic support membrane at...
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5601842 |
Sustained release drug formulation containing a tramadol salt
A drug formulation of tramadol or a tramadol salt in orally administrable tablet form containing at least one pharmaceutically acceptable matrixing agent is disclosed from which a non-moisture...
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5595592 |
Dye compositions and methods for film coating tablets and the like
An improved dye composition for use in coating tablets and the like is constituted by a stable, aqueous suspension containing a water-soluble, nontoxic dye, an opacifying agent which may be...
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5595759 |
Process for providing therapeutic composition
A process is disclosed and claimed for preparing a therapeutic composition comprising asteroid or a dosage form comprising the composition, which therapeutic composition or dosage form is indicated...
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5593694 |
Sustained release tablet
A sustained release tablet comprising a base tablet comprising a water-swellable gelling agent and a pharmaceutically active ingredient dispersed homogeneously in said gelling agent, said base...
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5594030 |
Controlled release pharmaceutical compositions based on one or more pharmaceutically acceptable salts of gamma hydroxy-butyric acid
Controlled release pharmaceutical compositions administrable by oral route, containing as the active principle at least one salt of the gamma hydroxy butyric acid with a pharmaceutically acceptable...
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5589191 |
Slow-release sodium valproate tablets
A slow, release sodium valproate tablet with a coating layer, obtained by coating a core containing sodium valproate with a coating agent comprising ethyl cellulose having silicic acid anhydride...
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5585115 |
Pharmaceutical excipient having improved compressability
A microcrystalline cellulose-based excipient having improved compressibility, whether utilized in direct compression, dry granulation or wet granulation formulations, is disclosed. The excipient is...
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