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6143326 |
Oral pharmaceutical preparation containing ibandronat
The invention is directed to well-tolerated pharmaceutical compositions for oral application, containing ibandronate or a physiologically tolerable salt thereof as active substance, the...
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6143327 |
Delayed release coated tablet of bupropion hydrochloride
The invention provides a delayed release coated tablet, free of stabilizer and free of pore-forming agent comprising: (i) a core consisting essentially of bupropion hydrochloride, a binder and a...
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6132772 |
Extended-release solid oral dosage forms of drugs having low solubility in water
The present invention relates to extended-release solid oral dosage forms of a drug having low solubility in water are obtained by dissolving the drug in polyethylene glycol having a mean molecular...
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6129930 |
Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night
An orally administered antihyperlipidemia composition according to the present invention includes from about 250 to about 3000 parts by weight of nicotinic acid, and from about 5 to about 50 parts...
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6123964 |
Wet granulation formulation of a growth hormone secretagogue
The present invention relates to a pharmaceutical composition and a process for the preparation of a tablet containing a growth hormone secretagogue as the active ingredient. The tablet is prepared...
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6124355 |
Oxybutynin therapy
A composition comprising oxybutynin, a dosage form comprising oxybutynin, and a method for administering oxybutynin are disclosed for oxybutynin therapy.
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6120802 |
Method of producing multi-layer medicaments in solid form for oral or rectal administration
The present invention relates to a process for producing multilayer, solid drug forms for oral or rectal administration, which comprises coextrusion of at least two compositions which in each case...
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6110500 |
Coated tablet with long term parabolic and zero-order release kinetics
A tablet for the controlled release of an active pharmaceutical ingredient. The tablet comprises a core having a donut-like configuration with a cylindrical hole extending through the center of the...
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6106863 |
Sustained-release metal valproate tablets
The present invention provides a sustained-release metal valproate tablet which is comparatively compact and is not influenced by a meal, the sustained-release metal valproate comprising a core...
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6099862 |
Oral dosage form for the controlled release of a biguanide and sulfonylurea
A controlled release pharmaceutical tablet containing antihyperglycemic drug and a hypoglycemic drug that does not contain an expanding or gelling polymer layer and comprising a core containing the...
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6096341 |
Delayed release tablet of bupropion hydrochloride
The invention provides a controlled release tablet, free of stabilizer and free of pore-forming agent comprising: (i) a core consisting essentially of bupropion hydrochloride, a binder and a...
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6090412 |
H.sub.2 -Receptor antagonist and antacid composition
A solid pharmaceutical composition for oral administration comprising a histamine H 2 -receptor antagonist, a low neutralizing capacity antacid, and a high neutralizing capacity antacid coated...
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6086918 |
Oral peptide pharmaceutical products
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6082368 |
Nicotine candy cigarette
A nicotine candy is provided for consumption in small volumes and in a cigarette shaped package. Each portion of the candy is obtained by removing it from a cigarette shaped package from the end....
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6066336 |
Cholesterol-lowering tablets
An improved cholesterol-lowering tablet is manufactured by blending tablet grade cholestyramine with an appropriate amount of lubricant and directly compressing into elongated tablets having a...
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6056975 |
Stabilized thyroid hormone preparations and methods of making same
Disclosed are thyroid hormone preparations useful in pharmaceutical applications. These preparations are disclosed to contain thyroxine drugs in combination with an inorganic salt, a carbohydrate...
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6051255 |
Polymer coated tablet comprising amoxycillin and clavulanate
The present invention is to a tablet formulation, being a medicament for oral administration for the treatment of bacterial infections, the tablet comprising a compacted mixture of 750-950 mg of...
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6045787 |
Protection of labile proteins during iodine disinfection
Mixtures of iodine source resin with iodine capture resin have been found to provide effective disinfecting of protein containing solutions such as plasma. These mixtures can be used in a...
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6039976 |
Enteric film coating compositions, method of coating therewith, and coated forms
A non-toxic edible enteric film coating dry powder composition for use in making an aqueous enteric coating suspension which may be used in coating pharmaceutical tablets and the like comprises an...
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6036973 |
Therapy for neurological diseases
A dosage form is disclosed for administering 10 ng to 1200 mg tacrine to a patient in need of tacrine therapy.
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6027748 |
Pharmaceutical tablet, completely coated, for controlled release of active principles that present problems of bio-availability linked to gastro-intestinal absorption
Described herein is a particular type of pharmaceutical tablet, for oral use, which is formed by one or more layers, and is specifically designed for controlled release of active principles that...
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6025391 |
Enteric-coated pharmaceutical compositions of mycophenolate
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6020001 |
Compositions for treating migraine
A pharmaceutical composition for oral adminstration comprising a film-coated solid dosage form including 3-[2-(dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulph
onamide or a pharmaceutically...
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6010718 |
Extended release formulations of erythromycin derivatives
Disclosed is a pharmaceutical composition for extended release of an erythromycin derivative in the gastrointestinal environment. The composition comprises an erythromycin derivative and a...
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6004558 |
Methods for treating cancer with legume plant extracts
The present invention relates to the preparation of therapeutic compositions comprising extracts of leguminous plants from which the isoflavones genistein, daidzein, formononetin and biochanin...
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6001391 |
Process for producing solid drug forms having at least two phases
A process for producing solid combination tablets which have at least two phases comprises molding a melt of a polymeric binder with or without at least one active ingredient, there being at least...
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5997905 |
Preparation of pharmaceutically active particles
The present invention provides a core of predominately microcrystalline cellulose, on which an active drug is layered onto the core via solution coating. The coated particles have a narrower...
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5989591 |
Rapamycin formulations for oral administration
This invention provides rapamycin solid dosage unit which comprises a core and a sugar overcoat, said sugar overcoat comprising rapamycin, one or more surface modifying agents, one or more sugars,...
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5981821 |
Dressing product with a calcium alginate matrix and method of production of the same
The dressing for a chronic wound with biological liquid, comprises a matrix of calcium alginate associated with at least one alginate of a multivalent metal, with the exception of magnesium. The...
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5962024 |
Peroral composition for controlled release in the lower gastrointestinal tract
The invention relates to a peroral composition providing controlled release of a drug, the composition comprising a) a core comprising the drug and a drug release controlling agent and b) an...
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5958459 |
Opioid formulations having extended controlled released
Solid controlled-release oral dosage forms comprising a therapeutically effective amount of an opioid analgesic or a salt thereof which provide an extended duration of pain relief of about 24...
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5955106 |
Pharmaceutical preparation containing metformin and a process for producing it
The present invention concerns pharmaceutical compositions containing metformin as an active substance and a hydrocolloid-forming agent as a retardant and optionally standard pharmaceutical...
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5922342 |
Lateral edge coated controlled release pharmaceutical compositions
The invention provides a controlled release composition comprising a compressed core containing a drug having two parallel planar surfaces (i.e. the top and bottom), and a seal coating surrounding...
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5916595 |
HMG co-reductase inhibitor
A controlled release dosage formulation is described which is based on a combination of: (a) a compressed tablet core which contains an alkyl ester of a hydroxy substituted naphthalene...
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5912014 |
Oral salmon calcitonin pharmaceutical products
Bioavailability of salmon calcitonin to be administered orally is enhanced by a pharmaceutical composition providing targeted release of the peptide to the intestine, together with an absorption...
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5912268 |
Dosage form and method for treating incontinence
A composition comprising oxybutynin, a device comprising oxybutynin, and a method for administering oxybutynin are disclosed for oxybutynin therapy.
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5908638 |
Pharmaceutical compositions of conjugated estrogens and methods for their use
This invention relates to novel pharmaceutical compositions and methods for their preparation containing conjugated estrogens for the treatment of peri-menopausal, menopausal and post-menopausal...
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5895663 |
Pseudoephedrine hydrochloride extended-release tablets
Pseudoephedrine hydrochloride extended-release tablets including a sustained release hydroxypropylmethylcellulose matrix and a microcrystalline cellulose disintegrant formed by a dry mixed, direct...
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5891474 |
Time-specific controlled release dosage formulations and method of preparing same
The present invention provides a method of achieving the time-specific delivery of a pharmaceutically active agent to a patient in need of the therapeutic effects of the pharmaceutically active...
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5888542 |
Matrix tablet allowing the prolonged release of the sodium salt of tianeptine after administration by the oral route
The invention relates to a matrix tablet for the prolonged release of the sodium salt of tianeptine which ensures a continuous and uniform release of the active ingredient after administration by...
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5882682 |
Controlled release simvastatin delivery device
Controlled delivery of a beneficial agent in a dispersion is provided using (i) a compressed core which contains the beneficial agent, a polymer which forms gelatinous microscopic particles upon...
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5876752 |
Use of interfacially-polymerized membranes in delivery devices
Devices for controlled release of active substances in the form of tablets, capsules and beads comprised of a porous substructure surrounded by one or more interfacial membranes.
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5869101 |
Process for the preparation of S(+)-ibuprofen-particles
A process for the production of S(+)-ibuprofen-particles having improved flow properties comprises the steps that coarse-crystalline S(+)-ibuprofen is molten and then in a molten condition is...
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5863559 |
Oral dosage form for treating migraine
A pharmaceutical composition for oral adminstration comprising a film-coated solid dosage form including 3- 2-(dimethylamino)ethyl!-N-methyl-1H-indole-5-methanesulphona
mide or a pharmaceutically...
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5861173 |
Long-lasting release nifedipine preparation
This invention provides a long-lasting release solid nifedipine preparation which exhibits clinically sufficient effect when administered once per day. A press coated tablet whose core and shell...
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5858412 |
Sustained release formulations utilizing pharmaceutical excipient having improved compressibility with modified microcrystalline
Sustained release formulations include an augmented microcrystalline cellulose, an active agent, and a sustained release carrier and methods for making same are disclosed.
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5858409 |
Hydrolyzed cellulose granulations for pharmaceuticals
The present invention provides a method for preparing a spray-dried compressible granular formulation for preparing pharmaceutical tablets in which hydrolyzed cellulose is used as a granulation...
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5855914 |
Granules having core and their production
Granules having a core are produced by spraying core granules with a dispersion of a low substituted hydroxypropylcellulose (L-HPC), and, if necessary, simultaneously applying a dusting powder. The...
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5851579 |
Aqueous enteric coating compositions
The present invention sets forth an enteric coating composition comprising a blend of a) an alkali-soluble acrylic latex polymer and b) an aqueous solution of ammonium or alkaline salts of...
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5840754 |
Dosage form comprising oxybutynin
A composition comprising oxybutynin, a device comprising oxybutynin, and a method for administering oxybutynin are disclosed for oxybutynin therapy.
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