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5525354 |
Pharmaceutical preparation and process for its manufacture
In a pharmaceutical preparation for oral use containing a pharmacologically acceptable salt of a bisphosphonic acid, the improvement comprising: a drug delivery form of the preparation which is...
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5508044 |
Diltiazem pharmaceutical spheroid formulation
A solid oral dosage form comprising diltiazem (or a pharmaceutically acceptable salt thereof) in controlled release form and hydrochlorothiazide in immediate release form. Preferably, the...
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5505967 |
Microparticulate pharmaceutical delivery system
A pharmaceutical composition comprising a shaped enteric material having distributed therethrough preferably substantially uniformly, pharmaceutical loaded particles, said particles having a size...
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5505962 |
Controlled release pharmaceutical formulation
An improved controlled release tablet formulation for the release of potassium chloride through a differentially permeable membrane from which the release of potassium chloride can be accurately...
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5472710 |
Pharmaceutical preparation to be administered orally with controlled release of active substance and method for its manufacture
Pharmaceutical preparation to be administered orally with controlled release of active substance and method for its manufacture. Pharmaceutical preparation to be administered orally with controlled...
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5470581 |
Aqueous maltodextrin and cellulosic polymer film coatings
A method of coating substrates such as pharmaceutical tablets, food and confectionery forms, agricultural seeds and the like, with a protective film comprises the steps of mixing a cellulosic...
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5466461 |
Polysaccharide esters
New polysaccharide esters are disclosed, and more precisely esters of acidic polysaccharides chosen from the group formed by carboxymethylcellulose, carboxymethyl starch and carboxymethylchitin....
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5466464 |
Intrabuccally disintegrating preparation and production thereof
A solid preparation soluble in the buccal cavity, which is composed of a sugar comprising lactose and/or mannitol and 0.1-1.2 w/w%, based on the sugar, of agar and an active ingredient and has a...
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5425950 |
Controlled release pharmaceutical compositions
This invention relates to a controlled release pharmaceutical composition comprising: (a) an outer layer comprising a pH independent hydrophilic polymer together with one or more fillers; and (b)...
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5422123 |
Tablets with controlled-rate release of active substances
Tablets with zero order controlled-rate of release of the active substances, consisting of a core of defined geometrical form containing the active substance, polymer substances which swell on...
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5422121 |
Oral dosage unit form
Coating agents comprising a liquid phase, a polysaccharide decomposable in the colon, such as locust bean gum or guar gum, and a film forming polymer preferably having hydrophilic groups, which...
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5401515 |
Coated active agent-containing article
Aqueous coating compositions for forming elastomeric films around active cores (e.g., drugs) comprising a dispersion of pre-crosslinked polyorganosiloxane latex particles, colloidal silica...
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5366738 |
Controlled release drug dispersion delivery device
A device for the controlled delivery of a beneficial agent as a gelatinous dispersion consisting of (i) a core which contains a beneficial agent, a polymer which forms gelatinous microscopic...
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5328903 |
Composition for solid pharmaceutical preparations containing vitamin D3 derivative
A composition for solid pharmaceutical preparations containing a vitamin D 3 derivative capable of permitting the derivative to be uniformly distributed in the composition while being stabilized....
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5322693 |
Lactoneotrehalose, and its preparation and uses
Lactoneotrehalose, a novel saccharide shown by the formula O-β-D-galactopyranosyl-(1➝4)-O-β-D-glucopyranosyl α-D-glucopyranoside, is prepared by allowing a saccharide-transferring enzyme to...
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5294448 |
Delayed release formulations
Delayed release compositions comprising an active compound and amorphous amylose and having an outer coating comprising a film forming cellulose or acrylic polymer material, for example glassy...
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5277916 |
Tetracycline dosage form
A tetracycline pharmaceutical composition having a core element containing a tetracycline antibiotic and a core coating which dissolves more slowly in the stomach than in the intestine....
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5260304 |
Pharmaceutical preparation binding with gastric acid
Granules, possibly pressed into the form of tablets, contain at least one insoluble, complexed or slightly soluble active substance in powder form which can bind or neutralize acids and which does...
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5258436 |
Film-forming composition; method of producing same and use for coating pharmaceuticals and foods and the like
A water dispersible polymeric film-forming particulate composition for use in coating pharmaceuticals and foods or the like, produced by freeze-drying an aqueous solution of water-soluble cellulose...
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5252339 |
Pharmaceutical compositions containing orally absorbable glycosamimoglycans
Pharmaceutical compositions for oral use, preferably selected from capsules, tablets or sugar coated tablets, coated by an enterosoluble gastroresistant film, containing a lyophilizate consisting...
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5240712 |
Therapeutic agents
A high content of 2-(4-isobutylphenyl)propionic acid is achieved in a pharmaceutical composition by solidifying molten 2-(4-isobutylphenyl)propionic acid to provide a unit dose composition. The...
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5225206 |
Sustained-release pranoprofen preparation
A sustained-release pranoprofen preparation is disclosed. The preparation comprises an effective amount of pranoprofen and one or more sustained-release components selected from the group...
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5224989 |
Film-forming dispersion for a protective coating of drug and food containing articles and objects
A film-forming dispersion for the formation of protective coatings on shaped drug and food articles which comprises 1 to 25 weight percent of acetylester of oxidized starch and 0.8 to 8 weight...
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5219575 |
Compositions with controlled zero-order delivery rate and method of preparing these compositions
The present invention relates to compositions having a controlled zero-order delivery rate of the active component. The composition comprises a core or a protective layer coated with a continuous...
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5217720 |
Coated solid medicament form having releasability in large intestine
A coated solid medicament form suitable for oral administration having reliable releasability of the active ingredient only in the large intestine is proposed. The medicament form is prepared by...
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5167949 |
4(3H)-pteridinones, preparation processes and drugs containing them
The present invention relates to 4(3H)-pteridinones represented by the formula: ##STR1## in which X is an oxygen atom or a sulphur atom, Y is a hydrogen atom, a lower alkyl radical, especially a...
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5162117 |
Controlled release flutamide composition
A controlled release solid dosage tablet of flutamide is disclosed that is designed to provide an immediate release dose and a second delayed dose in pulsatile manner in the gastrointestinal tract...
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5158772 |
Unique bacterial polysaccharide polymer gel in cosmetics, pharmaceuticals and foods
Topical compositions for application to the skin comprising a topically active agent which may be a cosmetic agent or a therapeutic agent, and a small, but carrier effective amount of a microbial...
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5114720 |
Gelatin coated tablets and method for producing same
Pharmaceutical tablets having increased slipperiness and swallowability are provided. The enhanced swallowability is imparted by an overcoat of a low bloom gelatin, which overcoat has a lower...
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5110605 |
Calcium polycarbophil-alginate controlled release composition and method
A polymeric complex composition comprising a reaction complex formed by the interaction of a polycarbophil component with alginic acid or a salt thereof, said interaction being performed in the...
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5108758 |
Delayed release formulations
Delayed release compositions comprising an active compound and glassy amylose. A variety of different types of active compound may be employed in the compositions. The compositions are particularly...
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5098715 |
Flavored film-coated tablet
The invention comprises a flavored thin film coating on solid oral dosage pharmaceutical tablets containing unpleasant tasting ingredients such as triprolidine hydrochloride and pseudoephedrine...
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5091184 |
Coated adhesive tablets
The invention relates to a pharmaceutical composition for the application of baclofen, in the form of an adhesive tablet, to the mucosa in the oral cavity, which pharmaceutical composition...
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5091191 |
Pharmaceutical composition with improved dissolution property
A pharmaceutical composition of the active agent sodium 4-[α-hydroxy-5-(1-imidazolyl)-2-methylbenzyl]-3,5-dimethylb
enzoate (a thromboxane synthetase inhibitor for treatment of diseases such as...
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5089251 |
Aromatic derivatives and their use as antimicrobial agents
The present invention relates to aromatic derivatives of the formula: ##STR1## in which: n represents an integer between 2 and 10; R 1 and R 2 are identical or different and represent a...
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5087454 |
Ibuprofen tablet
Ibuprofen tablets/caplets formed by wet granulation of the ibuprofen characterized by a dissolution profile maintained stable on aging by incorporating croscarmellose sodium separately into the wet...
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5080906 |
Method and composition for oral administration of N-acetylcysteine
The blood level of orally administered N-acetylcysteine is substantially increased in a mammal when the N-acetylcysteine is administered in combination with tris(hydroxymethyl)aminomethane or a...
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5047246 |
Direct compression cyclophosphamide tablet
A directly compressible pharmaceutical composition comprising cyclophosphamide and a partially or fully pregelatinized starch is disclosed. The pharmaceutical composition, when directly compressed...
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5043167 |
Galenic formulations with programmed release
New galenic formulations with programmed release, to be administered by the oral route, containing as the active ingredient a drug selected from the non steroidal antiinflammatory, bronchodilator,...
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5037657 |
Effervescent acetysalicylic acid
The rate of disintegration and/or dissolution of effervescent acetylsalicylic acid tablets obtained by direct compression of a dry powder mixture is surprisingly increased by incorporating in said...
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5023083 |
Azarbine composition
A method for treating azaribine-responsive diseases in patient's who exhibit severe pyridoxal phosphate depletion following the oral administration of azaribine comprises first encapsulating...
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4996061 |
Pharmaceutical composition for piperidinoalkanol-decongestant combination
The present invention relates to a pharmaceutical composition in the form of a multiple-compression tablet comprising (a) a discrete zone made with Formulation (A) which comprises a carrier base...
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4968508 |
Sustained release matrix
This invention provides a matrix composition for sustained drug delivery which is comprised of an active agent, a hydrophilic polymer and an enteric polymer. The enteric polymer is impermeable to...
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4966772 |
DHP delayed release preparation
A solid medicament preparation having long-lasting action containing a sparingly soluble dihydropyridine active compound of the Formula (I) ##STR1## the preparation having a core-coating...
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4961890 |
Method of preparing comtrolled release fenofibrate
A process for preparing a controlled release medicine containing fenofibrate in an intermediate layer in the form of cyrstalline microparticles included within pores of an inert matrix prepared by...
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4952410 |
Pharmaceutical products of moxonidine and hydrochlorothiazide
Pharmaceutical composition containing moxonidine (4-chloro-6-methoxy-2-methyl-5-(2-imidazolin-2-yl)aminopyrim
idine) or its pharmaceutically acceptable salts and hydrochlorothiazide...
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4927636 |
Association complex comprising pullulan and polyethylene glycol, and preparation and uses of the same
Pullulan forms an association complex with PEG in a hydrous system. The assocation complex, as well as its pullulan and PEG components, exerts a decreased solubility in water. The association...
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4910022 |
Phthalazineacetic acid composition and tablet
A tablet composition for a phthalazineacetic acid compound to be employed in treating clinical effects associated with diabetes is described. The composition permits formation of tablets having a...
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4904477 |
Spray dried ibuprofen compositions
A spray dried ibuprofen composition suitable for direct compression into tablets comprising a spray dried dispersion in water of ibuprofen, pregalatinized starch, a disintegrant and a wetting agent...
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4892741 |
Press coated DHP tablets
The invention relates to solid pharmaceutical preparations which have a long-lasting action and are for dihydropyridines in the form of a press coated tablet, and a process for their preparation.
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