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6126962 |
Crystalline powdery saccharide, its preparation and uses
A stable crystalline powdery saccharide having a crystallinity of 40% or more, less hygroscopicity, satisfactory fluidity, and beneficial handleability, which is obtainable from an aqueous...
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6124355 |
Oxybutynin therapy
A composition comprising oxybutynin, a dosage form comprising oxybutynin, and a method for administering oxybutynin are disclosed for oxybutynin therapy.
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6110500 |
Coated tablet with long term parabolic and zero-order release kinetics
A tablet for the controlled release of an active pharmaceutical ingredient. The tablet comprises a core having a donut-like configuration with a cylindrical hole extending through the center of the...
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6099862 |
Oral dosage form for the controlled release of a biguanide and sulfonylurea
A controlled release pharmaceutical tablet containing antihyperglycemic drug and a hypoglycemic drug that does not contain an expanding or gelling polymer layer and comprising a core containing the...
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6056975 |
Stabilized thyroid hormone preparations and methods of making same
Disclosed are thyroid hormone preparations useful in pharmaceutical applications. These preparations are disclosed to contain thyroxine drugs in combination with an inorganic salt, a carbohydrate...
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6048541 |
Fast-dissolving comestible units formed under high-speed/high-pressure conditions
The invention relates to compositions useful for making tablets which can be formed using conventional tableting machines and which disintegrate rapidly in the mouth with optional chewing. The...
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6036973 |
Therapy for neurological diseases
A dosage form is disclosed for administering 10 ng to 1200 mg tacrine to a patient in need of tacrine therapy.
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6033713 |
Thickened hydrolyte isotonic beverage
A prethickened hydrolytic beverage useful in rehydrating and regaining electrolytic balance with those suffering from dysphagia. Said beverage contains water, a carbohydrate source, a modified food...
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6025391 |
Enteric-coated pharmaceutical compositions of mycophenolate
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6015577 |
Pharmaceutical compositions containing dipyridamole or mopidamol and acetylsalicylic acid or the physiologically acceptable salts thereof, processes for preparing them and their use in treating clot formation
The specification describes a pharmaceutical combination consisting of dipyridamole or mopidamol and acetylsalicylic acid or the physiologically acceptable salts thereof, processes for preparing...
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5997905 |
Preparation of pharmaceutically active particles
The present invention provides a core of predominately microcrystalline cellulose, on which an active drug is layered onto the core via solution coating. The coated particles have a narrower...
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5989591 |
Rapamycin formulations for oral administration
This invention provides rapamycin solid dosage unit which comprises a core and a sugar overcoat, said sugar overcoat comprising rapamycin, one or more surface modifying agents, one or more sugars,...
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5977069 |
Pharmaceutical formulation
A pharmaceutical preparation comprising a growth hormone and asparagine as additive or buffering substance shows a very high stability against deamidation, oxidation and cleavage of peptide bonds....
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5965162 |
Process for forming chewable quickly dispersing multi-vitamin preparation and product therefrom
A composition and method for preparing multi-vitamin comestible units which disperse quickly in the mouth, especially when chewed, includes initiating crystallization of shearform matrix with...
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5935636 |
Trehalose and its production and use
Microorganisms which are able to produce maltose/trehalose conversion enzyme, a novel enzyme, are cultivated in nutrient culture media with malose. During the cultivation, the microorganisms...
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5922342 |
Lateral edge coated controlled release pharmaceutical compositions
The invention provides a controlled release composition comprising a compressed core containing a drug having two parallel planar surfaces (i.e. the top and bottom), and a seal coating surrounding...
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5914132 |
Pharmaceutical dosage form with multiple enteric polymer coatings for colonic delivery
The present invention relates to a pharmaceutical composition in a unit dosage form for peroral administration in a human or lower animal, having a gastrointestinal tract comprising a small...
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5912268 |
Dosage form and method for treating incontinence
A composition comprising oxybutynin, a device comprising oxybutynin, and a method for administering oxybutynin are disclosed for oxybutynin therapy.
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5885592 |
Methods and pharmaceutical compositions for oral delivery of molecular iodine
The invention is a method of administering therapeutic iodine for treating a disorder in a mammal. The invention comprises a step of feeding said mammal an effective amount of an oxidant for an...
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5882682 |
Controlled release simvastatin delivery device
Controlled delivery of a beneficial agent in a dispersion is provided using (i) a compressed core which contains the beneficial agent, a polymer which forms gelatinous microscopic particles upon...
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5882707 |
Method of coating an edible substrate with sugar/syrup or sugarless solutions containing dry color concentrate
A dry color concentrate for use in coloring sugar/syrup solutions and sugarless syrup solutions used to coat confectionery forms, pharmaceutical tablets, and the like, comprises 1) a carbohydrate...
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5882715 |
Method of preparing an oral preparation provided on the outer side with an enteric coating, as well as an oral preparation obtained by the method
A method of preparing an oral preparation, especially in the form of hard gelatin capsules, tablets or pellets, for use by the administration of drugs or supplementary nutrients for human beings or...
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5866619 |
Colonic drug delivery system
A colonic delivery system for delivering a drug to the colon is provided. The system comprises a drug in combination with a matrix, wherein the matrix comprises a saccharide-containing polymer....
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5849327 |
Delivery of drugs to the lower gastrointestinal tract
Diseases of the colon are treated by oral ingestion of a unit dosage form containing a plurality of porous microscopic beads, the pores containing an active agent or drug and plugged with a...
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5843479 |
Bisacodyl dosage form with multiple enteric polymer coatings for colonic delivery
The present invention relates to a pharmaceutical composition in a unit dosage form for peroral administration in a human or lower animal, having a gastrointestinal tract comprising a small...
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5840754 |
Dosage form comprising oxybutynin
A composition comprising oxybutynin, a device comprising oxybutynin, and a method for administering oxybutynin are disclosed for oxybutynin therapy.
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5837285 |
Fast soluble tablet
The object of the present invention is to provide a tablet that dissolves rapidly in the oral cavity (fast soluble tablets) that can be produced by a simple method without special preparation...
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5811388 |
Delivery of drugs to the lower GI tract
Pharmaceutical compositions for orally delivering a therapeutically effective amount of a drug to the colon without significant release of the drug in the upper GI tract after oral administration...
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5788964 |
Method for sensitization of cancer cells for killer cell mediated lysis
The invention relates to a method of sensitizing cancer cells for a killer cell mediated lysis which involves administering to a patient an effective amount of antiestrogen and killer cells either...
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5785995 |
Pharmaceutical tablet of amiodarone salt
An orally administered tablet comprising a therapeutic amount of a pharmaceutically acceptable salt of amiodarone (e.g., an acid salt of amiodarone such as amiodarone hydrochloride) is described....
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5759577 |
Controlled release of steroids from sugar coatings
A compressed medicinal tablet comprising a tablet core and a sugar coating, said sugar coating containing a dose of a hormonal steroid and a steroid release rate controlling amount of...
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5753265 |
Multiple unit pharmaceutical preparation
A new pharmaceutical multiple unit tableted dosage form containing as active ingredient an acid labile H + K + -ATPase inhibitor or an alkaline salt thereof or one of its single enantiomers or an...
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5725880 |
Pharmaceutical preparation controlled to release medicinal active ingredient at targeted site in intestinal tract
A pharmaceutical preparation for oral administration which is controlled to release a medicinal active ingredient at a targeted site in the intestinal tract comprising (a) a core containing a...
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5720974 |
Fast dissolving tablet and its production
A method of producing a fast dissolving tablet comprising compression-molding a composition comprising an active ingredient, a carbohydrate and a barely sufficient amount of water to moisten the...
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5721221 |
Lowering blood cholesterol levels using water soluble cellulose ethers
A method for reducing the cholesterol level in mammalian blood by administering a water soluble cellulose ether thereto. The cellulose ethers have a viscosity, measured as a 2% aqueous solution at...
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5714168 |
Method for increasing flowability of spray dried vitamin powders having low vitamin concentrations
The present invention relates to a method for increasing the flowability of spray dried vitamin powders having low vitamin concentrations and high concentrations of a maltodextrin carrier by...
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5705183 |
Cotton candy coated medication and a method for making and administering the same
A system and a method are provided to spray sugar in fibrous form and compress the same and subsequently add medication to form a dose appropriate for ingestion by a patient. Alternatively, the...
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5702724 |
Process for the preparation of an oral solid dosage form containing diclofenac
The invention relates to a novel advantageous process for the preparation of an oral solid dosage form containing diclofenac or a pharmaceutically acceptable salt thereof. The dosage form is...
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5667805 |
Morphine therapy
A composition comprising morphine; and a dosage form comprising morphine are disclosed for morphine therapy. A method of using the composition and the dosage form are disclosed and indicated for...
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5662936 |
Sugar-coated pharmaceutical dosage unit
The invention relates to sugar-coated dosage units comprising a steroid having two hydrogen atoms at position 3 of the steroid skeleton, such as desogestrel, allylestrenol, ethylestrenol, or...
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5654004 |
Oral pharmaceutical preparation releasable in the lower digestive tract
An oral pharmaceutical preparation releasable in the lower digestive tract, characterized by having a double-coated structure wherein a solid drug having a core containing an active ingredient is...
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5629003 |
Rapidly disintegrating sheet-like presentations of multiple dosage units
A presentation which, in the form of a film, permits the individual dosage of drugs, confectionary, other food, cosmetics and the like for oral application or intake. The presentation is...
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5616343 |
Cross-linked amylose as a binder/disintegrant in tablets
The present invention is concerned with the manufacture of solid dosage units (pharmaceutical and others). More specifically, the invention is related to powders of cross-linked amylose, having a...
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5614199 |
Inclusion complexes of clavulanic acid and of alkali salts thereof with hydrophilic and hydrophobic β-cyclodextrin derivatives, a process for the preparation thereof and the use thereof
Described is a new process for the preparation of alkali clavulanate from an aqueous solution of crude clavulanic acid, which is obtained in a conventional manner after the fermentation with a...
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5585365 |
Antiviral polysaccharide
An antiviral polysaccharide purified from an extract prepared by extracting Spirulina cells with hot water, having the following properties: (1) it comprises rhamnose, glucose, fructose, ribose,...
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5582838 |
Controlled release drug suspension delivery device
A device is disclosed for the controlled delivery of a beneficial agent, the device consisting of (i) a core comprising at least two layers, wherein at least one layer comprises a beneficial agent...
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5571534 |
Drug formulations for parenteral use
This invention relates to parenteral preparations of antiestrogens such as toremifene, desmethyl toremifene, tamoxifen or desmethyltamoxifen. The preparations can be emulsions, liposomes or aqueous...
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5567439 |
Delivery of controlled-release systems(s)
The present invention is a method and a dosage unit for delivery of a controlled-release system. The dosage unit is a quick dissolve unit which can be prepared by mixing uncured shearform matrix...
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5543154 |
Controlled release nifedipine delivery device
A device for the controlled delivery of a beneficial agent as a gelatinous dispersion consisting of (i) a core which contains a beneficial agent, a polymer which forms gelatinous micoroscopic...
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5536507 |
Colonic drug delivery system
A three component pharmaceutical formulation of one or more pharmacologically active substances such that greater than 80% of the pharmacologically active substance will be released in the large...
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