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7229642 |
Amino acid modulated extended release dosage form
Disclosed herein is a oral extended release dosage form comprising a plurality of granules of an effective amount of a pharmaceutically active compound, at least one amino acid, and an...
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7012129 |
Antiviral composition comprising glycine amide
Embodiments relate to the discovery that certain tripeptide amides and glycine amide can be used to inhibit viral infection, including human immunodeficiency virus (HIV) infection. More...
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6994873 |
Multiparticulate formulations of lithium salts for oral administration suitable for once-a-day administration
This invention refers to:
multiparticulate formulations of Lithium salts for oral administration constituted by either modified release granules or mixtures of modified and conventional...
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6946145 |
Block copolymers based on poly(ortho esters) containing amine groups
Block copolymers based on poly(ortho esters) containing amine groups. These block copolymers have both hydrophilic and hydrophobic blocks. They form micelles in aqueous solution, making them...
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6946146 |
Coating for a sustained release pharmaceutical composition
The present invention is directed to a coating composition for coating a solid dosage form of a medicament, where the coating composition controls the release of the medicament, said coating...
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6867181 |
Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
A method of spherifying a sustained release ionic conjugate which contains a free carboxyl group-containing polymer and a free amino group-containing drug which are ionically bonded to each other.
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6783771 |
Physiologically active substance EEM-S originating in mushrooms, process for producing the same and drugs
EEM-S obtained by extracting with hot water or a lower alcohol at least one mushroom selected from among Lentinus edodes, Flammulina velutipes, Hypsizygus marmoreus, Pleurotus ostreatus, Pholiota...
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6706284 |
Bitterness-reduced oral pharmaceutical composition
The invention relates to an oral pharmaceutical composition which has excellent drug release-controlling ability in the mouth even 5 to 10 minutes after its administration and also has excellent...
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6616944 |
Self-assembling colloidal carriers for protein delivery
The invention is directed to self-assembling, polymer-based delivery systems for proteins. The delivery systems comprises an active agent and a polyol ester of the invention, having a linear polyol...
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6610329 |
Compositions for the delivery of antigens
The present invention relates to compositions and methods for orally delivering antigens. The antigen and an adjuvant are combined with an acylated amino acid or polyamino acid and, a sulfonated...
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6531152 |
Immediate release gastrointestinal drug delivery system
A gastrointestinal delivery system is provided. The system comprises a drug in combination with a swellable core material, the core being surrounded by a water-insoluble or relatively...
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6429193 |
CELL CHEMOTACTIC FACTOR (CCTF) ORIGINATING IN MAMMALIAN TOOTH PRICEMENT OR CEMENT, METHOD FOR PURIFYING THE SAME, AND NOVEL CONNECTIVE TISSUE ADHESION PROMOTERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT
A precementum- and/or cementum-derived chemotactic factor (CCTF) of a tooth of a Mammalian is characterized by a molecular weight measured by SDS-PAGE of 67000±1000. A process for purifying a...
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6387404 |
Immediate release tablet cores of insoluble drugs having sustained-release coating
A controlled release tablet for oral administration is disclosed which has a tablet core including an insoluble therapeutically active agent having an aqueous solubility of less than or equal to...
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6319683 |
Method and composition for controlling formaldehyde fixation by delayed quenching
A method and composition for quenching formaldehyde fixation of cell and tissue specimens. The composition includes a formaldehyde-reactive agent. The formaldehyde-reactive agent reacts with the...
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6210714 |
Immediate release tablet cores of acetaminophen having sustained-release coating
A controlled release tablet for oral administration is disclosed which has a tablet core including an insoluble therapeutically active agent having an aqueous solubility of less than or equal to...
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6197314 |
Impeding the extraction of active ingredients out of tablets
Solid oral administration forms from which the active ingredients can be isolated only with difficulty are described and comprise, besides conventional ingredients, as addition a mixture of...
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6086918 |
Oral peptide pharmaceutical products
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6077540 |
Gelatin spray coating
This invention provides a coating composition in which the principal film former is gelatin for use in coating tablets. The gelatin coating may be used with tablets, with or without any subcoating,...
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6056974 |
Rapid-release S1452 tablets
The present invention provides a rapid-release tablet of S1452 at least containing the following components: a. a principal agent comprising (+)-(Z)-calcium...
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6030640 |
Oligoglycine compound, fibrous microtube of oligoglycine compound and process of producing fibrous microtube
A lipid represented by the following formula: MO--(CO--CH 2 --NH) p --CO--(CH 2 ) n --CO--(NH--CH 2 --CO) q --OM wherein M represents a hydrogen atom or an alkali metal, n is an integer of...
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5912014 |
Oral salmon calcitonin pharmaceutical products
Bioavailability of salmon calcitonin to be administered orally is enhanced by a pharmaceutical composition providing targeted release of the peptide to the intestine, together with an absorption...
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5882715 |
Method of preparing an oral preparation provided on the outer side with an enteric coating, as well as an oral preparation obtained by the method
A method of preparing an oral preparation, especially in the form of hard gelatin capsules, tablets or pellets, for use by the administration of drugs or supplementary nutrients for human beings or...
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5876748 |
Fibrous microtube of oligoglycine compound
A lipid represented by the following formula: MO--(CO--CH 2 --NH) p --CO--(CH 2 ) n --CO--(NH--CH 2 --CO) q --OM wherein M represents a hydrogen atom or an alkali metal, n is an integer of...
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5753265 |
Multiple unit pharmaceutical preparation
A new pharmaceutical multiple unit tableted dosage form containing as active ingredient an acid labile H + K + -ATPase inhibitor or an alkaline salt thereof or one of its single enantiomers or an...
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5750145 |
Stable gelatin coated aspirin tablets
Gelatin coated pharmaceutical dosage units containing, for example, analgesic compounds, such as aspirin, stabilized with a proteolytic enzyme, such as pepsin, are described.
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5455286 |
Bioactive composition
An improved bioactive agent delivery composition and method of application are described. The composition comprises a bioactive agent, a hydrophilic polymer in an incompletely hydrated state and a...
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5451410 |
Modified amino acids for encapsulating active agents
Modified amino acids and methods for their preparation and use as oral delivery systems for pharmaceutical agents are described. The modified amino acids are preparable by reacting single amino...
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5393333 |
Film-forming product for coating solid forms, process for its manufacture and products coated with this film-forming product
The present invention relates to a film-forming product for coating solid forms, to a process for the manufacture of this film-forming product and to products coated with this film-forming product....
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5350741 |
Enteric formulations of physiologically active peptides and proteins
An enteric formulation for a proteinous drug which protects it from enzymatic degradation and promotes its uptake by the intestinal tract when administered orally, comprises either a solid mass of...
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5328697 |
Compositions and processes for the sustained release of drugs
The present invention relates to compositions for the sustained release of drugs and to methods for the production of such compositions. In one embodiment, somatotropin is layered onto non-pareil...
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5240712 |
Therapeutic agents
A high content of 2-(4-isobutylphenyl)propionic acid is achieved in a pharmaceutical composition by solidifying molten 2-(4-isobutylphenyl)propionic acid to provide a unit dose composition. The...
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5189148 |
Stabilized FGF composition and production thereof
Disclosed are (1) a stabilized FGF protein composition which comprises an FGF protein and water-insoluble hydroxypropyl cellulose; (2) a method for preparing a stabilized FGF protein composition,...
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5185159 |
Pharmaceutical composition based on valproic acid and a process for preparing it
New pharmaceutical composition based on valproic acid and one of the pharmaceutically acceptable salts thereof, obtained by a new galenic preparation process which makes it possible to improve and...
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5182130 |
Method for producing an edible prolamine coating from an aqueous latex
A continuous edible coating or barrier is formed on a substrate by applying to the substrate a water-based prolamine latex which is substantially free of organic solvent. Additives to the latex may...
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5077053 |
Zein as a moisture barrier for sugarless edible compositions and method for preparing same
The present invention pertains to an edible coated composition which comprises (a) a core material comprising sorbitol, (b) a primary coating layer comprising zein over the core material, and (c) a...
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5025004 |
Water-dispersible polymeric compositions
Disclosed is a process for preparing polymeric compositions which are suitable for coating medicaments or for use in cosmetic formulations and the novel compositions prepared therefrom. The process...
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5023083 |
Azarbine composition
A method for treating azaribine-responsive diseases in patient's who exhibit severe pyridoxal phosphate depletion following the oral administration of azaribine comprises first encapsulating...
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5008112 |
Device for the extended delivery of diffusible agents
A device for the continuous administration of a diffusible agent having a relatively rapid rate of diffusion and a diffusible agent having a relatively show rate of diffusion comprises: a wall,...
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4908214 |
Pharmaceutical tablet for the treatment of uraemia
A tablet constituted by (1) a core comprising a mixture of salts formed by a basic α-amino acids and α-keto analogues of branched-chain essential amino acids and (2) a gastroresistant or...
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4844907 |
Pharmaceutical composition comprising analgesic and anti-inflammatory agent
A pharmaceutical composition in the form of a multiphase (especially a bilayered, optionally coated) tablet. The tablet has a narcotic analgesic phase containing a therapeutically effective...
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4711783 |
Forms of microencapsulation of medicinal substances by homogeneous layers of native collagen
A new sustained-release, microencapsulated pharmaceutical composition is disclosed, suitable for oral administration which contains an effective amount of an orally-administered pharmaceutical in...
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4457907 |
Composition and method for protecting a therapeutic drug
A therapeutic composition comprising a therapeutic drug that can cause undesirable effects on the pre-intestinal phases when contacting these phases, and an enteric coating surrounding the drug. A...
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4432966 |
Compressed tablets for disintegration in the colon comprising an active ingredient containing nucleus coated with a first layer containing microcrystalline cellulose which is coated with an enteric organic polymer coating
Coated compressed tablets for oral administration are disclosed which substantially desintegrate specifically at the level of the colon. The tablets comprise a compressed center piece containing an...
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3991180 |
Stabilization of internally administered pancreatic lipase
A method for treating exocrine pancreatic insufficiency is disclosed. The method comprises the administration of a stable solid medicinal preparation containing finely particulated lipase...
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3887699 |
Biodegradable polymeric article for dispensing drugs
An article for dispensing drugs is disclosed which is formed from a biodegradable polymeric material and a drug. The drug is intimately dispersed throughout the polymer and the combination is...
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3802896 |
COLOR CONCENTRATED BASE DISPERSION USED IN TABLET FILM COATING
An improved color concentrated base dispersion adapted to form a film coating mixture is disclosed. The color concentrated base dispersion contains a pigment, dye (optional) and at least one...
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3608064 |
MILK-BUFFERED ASPIRIN
A mixture of aspirin and powdered milk.
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3535305 |
LOW TEMPERATURE SOLVENT EXTRACTION PROCESS FOR PRODUCING HIGH PURITY ZEIN
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3524756 |
PROCESS OF COATING TABLETS WITH ALTERNATE TACKY AND NON-TACKY LAYERS
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3483008 |
METHOD OF PREPARING A WATER-SOLUBLE PROTEIN LOTION
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