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6270799 |
Medicament formulation with a controlled release of an active agent
The invention relates to drug formulations which comprise 1-cyclopropyl-7-([S,S]-2,8-diazabicyclo[4.3. 0]non-8-yl)-6-fluoro-1,4-dihydro-8-methoxy-4-oxo-3-quino-lon
ecarboxylic acid and/or...
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6267986 |
Process for the preparation of a controlled drug delivery system containing pseudoephedrine and a long acting antihistamine
This invention relates to a process for the preparation of a controlled release pharmaceutical composition comprising two discrete zones wherein the first discrete zone comprises therapeutically...
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6264985 |
Laminated tablet with pointed core
A dry-coated tablet for controlled release of active substance, having an erodible core tablet (1) containing at least one active substance, and a substantially erosion-resistant shell consisting...
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6264974 |
Buccal and sublingual administration of physostigmine
Physostigmine, 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo[2,3-b] indol-5ol methylcarbamate, administered buccally or sublingually in non-sustained release dosage form provides extremely...
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6258381 |
Tablet and process for making the same
A tablet and process for making the same is provided. The tablet is made from a granular agglomerate comprising a mixture of at least one active ingredient and a binder. The granular agglomerate is...
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6254866 |
Use of phage associated lytic enzymes for treating bacterial infections of the digestive tract
A method for treatment of bacterial infections of the digestive tract is disclosed which comprises administering a lytic enzyme specific for the infecting bacteria. The lytic enzyme is preferably...
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6251430 |
Water insoluble polymer based sustained release formulation
Sustained release drug formulations contain the pharmaceutical itself and a three component release rate controlling matrix composition. The three components of the matrix composition are (1) water...
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6248355 |
Pharmaceutical composition containing an acid-labile omeprazole and process for its preparation
A composition, particularly adapted for oral administration, containing omeprazole, and a method for preparing the composition, are disclosed. The composition, being exempt of alkaline-reacting...
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6248760 |
Tablet giving rapid release of nicotine for transmucosal administration
A tablet for the transmucosal administration of nicotine. The nicotine is in one or more layers upon a non-nicotine containing matrix. The nicotine layers rapidly dissolve in the mouth. The...
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6248359 |
Multi-tablet oxybutynin system for treating incontinence
The present invention provides a simple multi-tablet system for the treatment of urinary incontinence with oxybutynin. Particular embodiments of the invention provide a first tablet that releases...
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6248307 |
Compositions and treatment for alleviation of symptoms associated with menopause
A composition having at least one herbal compound and at least one homeopathic drug is useful for treating symptoms associated with menopause. Methods of preparing the composition and methods of...
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6238698 |
Oral preparation containing at least one active pharmaceutical substance in a matrix capable of swelling in an aqueous medium
An oral preparation, comprising at least one pharmaceutical active compound in a matrix which is swellable in aqueous medium, which is released from the matrix into the aqueous medium in a delayed...
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6235311 |
Pharmaceutical composition containing a combination of a statin and aspirin and method
A pharmaceutical composition is provided which is useful for cholesterol lowering and reducing the risk of a myocardial infarction, which includes a statin, such as pravastatin, lovastatin,...
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6224911 |
Process for the preparation of enteric coated pharmaceutical dosage forms
This invention is directed to a process for the preparation of enteric coated pharmaceutical dosage forms. This invention is further directed to the aqueous enteric coating dispersions suitable for...
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6221395 |
Controlled release pharmaceutical tablets containing an active principle of low water solubility
It is described a new method for the preparation of pharmaceutical tablets carrying poorly soluble in water principle; this method allows to obtain tablets with fast and/or slow release of the...
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6221396 |
Oral cisapride dosage forms with an extended duration
The present invention provides sustained release oral solid dosage forms of cisapride by using a multi-particulate system, which are bioavailable and can provide efficient blood level of cisapride...
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6217903 |
Sustained release polymer blend for pharmaceutical applications
A pharmaceutical composition has a blend of at least first and second components and a medicament in a sufficient amount to be therapeutic where the first component is ethylcellulose (EC) and the...
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6214379 |
Maximizing effectiveness of substances used to improve health and well being
The present disclosure relates to novel dosage forms, drug delivery regimens, methods and pharmaceutical compositions which optimize the therapeutic effects of active therapeutic substances through...
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6200602 |
Composition for enhanced uptake of polar drugs from the colon
The invention provides a drug delivery composition for colonic delivery comprising a polar drug, an absorption promoter which (a) comprises a mixture of a fatty acid having 6 to 16 carbon atoms or...
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6197341 |
Formulations of balsalazide and its derivatives
The invention provides a unit formulation which comprises a 2-hydroxy-5-phenylazobenzoic acid derivative which is particularly sodium balsalazide dihydrate which formulation has a density of at...
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6197314 |
Impeding the extraction of active ingredients out of tablets
Solid oral administration forms from which the active ingredients can be isolated only with difficulty are described and comprise, besides conventional ingredients, as addition a mixture of...
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6197336 |
Fast dissolving compositions having analgesic activity
An analgesic composition useful in the preparation of fast dissolving tablets is provided, where the composition is the result of combining ibuprofen, arginine, linear PVP and an alkaline...
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6187341 |
Trovafloxacin mesylate tablet
Compositions, especially in the form of tablets containing the polymorph II form of trovafloxacin mesylate, a lubricant, and microcrystalline cellulose (MC) as the diluent. Such compositions...
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6187337 |
Rapidly dissolving dosage form
A particulate support matrix, and a dosage form made therefrom, and processes for making such support matrices and dosage forms, which disintegrate or dissolve in a matter of just a few seconds...
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6187340 |
Stabilized pharmaceutical preparation
A stabilized pharmaceutical preparation which is coated with a coating agent comprising an agent for the protection from light, said agent being capable of producing free radicals when exposed to...
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6183778 |
Pharmaceutical tablet capable of liberating one or more drugs at different release rates
Pharmaceutical tablet consisting of a first layer containing one or more drugs with immediate or controlled release formulation, a second layer containing one or more drugs, either equal to or...
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6183780 |
Oral delayed immediate release formulation and method for preparing the same
The invention relates to an Oral Delayed Immediate Release formulation comprising a compressed core containing one or more active substances surrounded with a coating, wherein release of active...
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6177101 |
Delavirdine high strength tablet formulation
Disclosed is a non-sustained release pharmaceutical tablet composition which comprises a rapidly precipitating drug in an amount from about 5 to about 60% and at least one member selected from the...
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6177102 |
Once daily analgesic tablet
An analgesic controlled release dosage form containing: (a) 40-80 weight percent of an analgesic; (b) 10-30 weight percent of a pharmaceutically acceptable filler; and (c) 10-30 weight percent of a...
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6174542 |
Dietary supplements and food products for treating symptoms of PMS
A chocolate containing dietary, vitamin, mineral and herbal supplement, and food products containing the same, for treating, preventing, alleviating or managing symptoms associated with...
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6172107 |
Entric-coated pharmaceutical compositions
This invention provides a pharmaceutical composition comprising a mycophenolate salt, the composition being adapted to release mycophenolate in the upper part of the intestinal tract.
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6159499 |
Composition containing an acid-labile benzimidazole and process for its preparation
The present invention relates to a composition, particularly adapted to oral administration, substantially free of alkaline-reacting compounds. The composition comprises (a) a core containing an...
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6156342 |
Controlled release oral dosage form
A controlled release dosage form for an analgesic that does not contain an expanding polymer and comprising a core containing the analgesic, preferably tramadol or it pharmaceutically acceptable...
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6156343 |
Controlled release preparation
A controlled release preparation consisting of a tablet containing (a) a mixture of a drug and a water-soluble polymer, or a solid dispersion thereof, (b) polyvinylalcohol and (c) one or more salts...
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6156340 |
Orally administrable time release drug containing products
A time release orally administrable drug containing product comprising a core, a drug layer attached to the core, and first and second coating layers is disclosed. The first coating layer is...
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6156341 |
Low-dosed steroid tablets that contain gallic acid ester as an antioxidant, process for production, and use
Pharmaceutical agents that contain a gallic acid ester as an antioxidant in combination with a steroidal active ingredient, their production and their use.
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6149940 |
Tablet with controlled release of alfuzosine chlorhydrate
Pharmaceutical tablet which consists of: a) a first layer having the property of swelling considerably and quickly on contact with aqueous biological fluids, the first layer being produced by...
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6149939 |
Healthful dissolvable oral tablets, and mini-bars
Dissolvable oral tablets and mini-bars which contain healthful ingredients. The products contain a multitude of discrete, extruded sections containing different healthful ingredients. A wide...
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6146661 |
Chewable tablet
Chewable tablets prepared by incorporating a sugar alcohol with a dissolution endotherm of 20 calories or more per gram of a gastrointestinally active ingredient such as a mucous membrane repairing...
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6143325 |
Nefazodone dosage form
Extended-release nefazodone compositions containing nefazodone hydrochloride, ionic and non-ionic gelling polymers, an insoluble hydrophilic agent, and optional pharmaceutically acceptable...
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6132769 |
Pharmaceutical matrix pellets, tablets and composition for the preparation thereof
The present invention relates to pharmaceutical matrix pellet formulations providing an adequate drug release profile. The matrix of said pellets is formed from: (a) a hydrophilic compound...
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6126970 |
Cisapride sustained release
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6124355 |
Oxybutynin therapy
A composition comprising oxybutynin, a dosage form comprising oxybutynin, and a method for administering oxybutynin are disclosed for oxybutynin therapy.
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6120802 |
Method of producing multi-layer medicaments in solid form for oral or rectal administration
The present invention relates to a process for producing multilayer, solid drug forms for oral or rectal administration, which comprises coextrusion of at least two compositions which in each case...
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6117450 |
Method of making a perorally administered solid drug with controlled effective ingredient delivery
The method of making a solid drug with controlled effective ingredient delivery for oral administration includes selecting a predetermined number of at least three of four compressed compositions...
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6113945 |
Multi-colored medicament
The medicament of the present invention and its process of manufacturing employs a caplet or tablet core with a clear or single color uniform covering which can be applied either through an...
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6110500 |
Coated tablet with long term parabolic and zero-order release kinetics
A tablet for the controlled release of an active pharmaceutical ingredient. The tablet comprises a core having a donut-like configuration with a cylindrical hole extending through the center of the...
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6106863 |
Sustained-release metal valproate tablets
The present invention provides a sustained-release metal valproate tablet which is comparatively compact and is not influenced by a meal, the sustained-release metal valproate comprising a core...
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6103264 |
Process for preparing a controlled release composition
A process for preparing a controlled release composition with a controlled release matrix and containing a pharmaceutically active ingredient, which comprises granulating the active ingredient with...
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6099862 |
Oral dosage form for the controlled release of a biguanide and sulfonylurea
A controlled release pharmaceutical tablet containing antihyperglycemic drug and a hypoglycemic drug that does not contain an expanding or gelling polymer layer and comprising a core containing the...
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