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6468959 |
Peroral dosage form for peptide containing medicaments, in particular insulin
There is provided a plural dosage form for peptide pharmaceuticals comprising a matrix of gelatin or gelatin derivative having distributed therein the peptide pharmaceutical in particular insulin,...
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6451342 |
Core formulation comprised of troglitazone and a biguanide
This invention relates to a controlled release combination drug product comprising troglitazone, e.g. its hydrochloride, and a biguamide, e.g. metformin. In particular, the product comprises a core...
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6451343 |
Composition for treating dementia and Alzheimer's disease
Controlled release dosage forms useful in the treatment and/or prophylaxis of dementia, including Alzheimer's disease, in mammals, and for enhancing amyloid precursor protein processing along a...
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6447797 |
Antibacterial phosphoinositides
It has been discovered that certain phosphoinositides demonstrate antibacterial activity. Particularly, these phosphoinositides have been discovered to prevent the adhesion of H. influenzae onto...
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6444218 |
Soft chewable multivitamin tablet comprising separated active ingredients
The present invention provides an improved soft chewable multivitamin tablet in which vitamin C is separated from calcium pantothenate and/or minerals such as iron, copper, zinc and mixtures...
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6440450 |
Soft chewable tablet comprising separated active ingredients
The present invention provides an improved soft chewable multivitamin tablet in which vitamin C is separated from calcium pantothenate and/or minerals such as iron, copper, zinc and mixtures...
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6440459 |
Paroxetine maleate polymorph and pharmaceutical compositions containing it
The form B of paroxetine maleate polymorph is characterized by determined data of X ray diffraction: it has a chemical stability which is superior to that of the form A of paroxetine maleate. This...
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6437006 |
Pharmaceutical carrier formulation
This invention provides carrier systems useful in preparing pharmaceutical formulations, the systems comprising, by weight percentage, from about 1% to about 20%, preferably from about 5% to about...
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6432447 |
Organic compounds
An oral dosage form comprising fluvastatin and HPMC, which oral dosage form is color-stable upon prolonged periods of storage.
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6432534 |
Process for the production of tablets and tablets
A method for producing tablet including active component, diluting agent, and lubricant by means of a tabletting machine provided with punches and dies, comprising steps of; preparing molding...
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6428810 |
Pharmaceutical formulation comprising omeprazole
An enteric coated oral pharmaceutical formulation comprising as active ingredient a compound selected from the group of omeprazole, an alkaline salt of omeprazole, one of the single enantiomers of...
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6428784 |
Vaginal suppository for treating group B Streptococcus infection
A composition for treatment of bacterial infections of the vagina is disclosed which comprises a lytic enzyme composition specific for the infecting bacteria, and a carrier for delivering said...
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6426091 |
Sustained-release theophylline tablet
A theophylline sustained release tablet obtained by coating core granules composed mainly of theophylline with a layer of a coating film composed of a hydrophobic material and a plastic excipient...
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6419959 |
Galenic composition containing opioid antagonists
A pharmaceutical composition for oral administration contains naloxone-, N-methylnaloxone- and/or N-methylnaltrexone-containing particles which release the active substance depending on the ambient...
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6413494 |
Composition and pharmaceutical dosage form for colonic drug delivery using polysaccharides
A colonic drug delivery composition contains a first polysaccharide and a second polysaccharide wherein both polysaccharide are degradable by colonic enzymes and are mixed at a environmental pH of...
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6399591 |
Chargeable pharmaceutical tablets
A blank tablet of this invention, typically, includes an absorbent, a disintegrant, a lubricant, and a diluent or a binder, or a mixture of a diluent and a binder. An active ingredient in liquid...
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6399097 |
Composition for treatment of a bacterial infection of the digestive tract
An enteric coated pill for treating bacterial infections of the digestive tract, wherein the bacteria to be treated are selected from the group consisting of Listeria, Salmonella, E. coli ,...
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6399086 |
Pharmaceutical preparations for the controlled release of beta-lactam antibiotics
The present invention relates to a pharmaceutical controlled-release oral drug delivery system comprising as active ingredient at least one β-lactam antibiotic agent, having a specific absorption...
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6399100 |
Controlled release pharmaceutical compositions containing tiagabine
Controlled release oral pharmaceutical preparations are provided which comprise a therapeutically effective amount of tiagabine or a pharmaceutically acceptable salt thereof dispersed in a rate...
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6387404 |
Immediate release tablet cores of insoluble drugs having sustained-release coating
A controlled release tablet for oral administration is disclosed which has a tablet core including an insoluble therapeutically active agent having an aqueous solubility of less than or equal to...
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6383518 |
Phosphate-binding polymer preparations
A tablet containing a phosphate-binding polymer, which has an average particle size of 400 μm or less, contains particles of 500 μm or less in particle size at a ratio of 90% or more and has a...
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6372252 |
Guaifenesin sustained release formulation and tablets
The invention relates to a novel pharmaceutical sustained release formulation of guaifenesin. The formulation may comprise a hydrophilic polymer, preferably a hydroxypropyl methylcellulose, and a...
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6372255 |
Tablet for instant and prolonged release of one or more active substances
A multi-layer tablet for the instant and prolonged release of active substances comprises at least two layers where the first outer layer comprises a mixture of excipients and an active substance,...
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6368627 |
Compositions
A pharmaceutical composition for oral adminstration comprising a film-coated solid dosage form including 3-[2-(dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulph
onamide or a pharmaceutically...
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6365209 |
Confectionery compositions and methods of making
A novel encapsulated product is provided and includes: at least one active ingredient; at least one compressible material; and at least one tableting material; wherein the encapsulated product is...
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6358528 |
Pharmaceutical formulation
A tablet formulation which comprises a core containing a pharmaceutically active material containing amoxycillin and clavulanate, coated with a release retarding coating, surrounded by a casing...
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6358527 |
Fast-dissolving galanthamine hydrobromide tablet
The present invention is concerned with a fast-dissolving tablet for oral administration comprising as an active ingredient a therapeutically effective amount of galanthamine hydrobromide (1:1) and...
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6358525 |
Sustained release polymer blend for pharmaceutical applications
A pharmaceutical composition has a blend of at least first and second components and a medicament in a sufficient amount to be therapeutic where the first component is hydroxypropylcellulose (HPC)...
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6344219 |
Chinese drug composition for treatment of peptic ulcer and preparation thereof
The present invention provides a Chinese drug composition for the treatment of peptic ulcer comprising oil of Chenopodium ambrosiodes and oil of Adina pilulifera in a ratio of 18-70:0.5-5 by...
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6342245 |
Compositions of lipid lowering agents
The present invention is concerned with novel pharmaceutical compositions of lipid lowering agents which can be administered to a mammal suffering from hyperlipidemia, obesitas or atherosclerosis,...
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6340474 |
Composition for potentiating a growth hormone and a method for preparation of said composition
A pharmacologically acceptable growth hormone-potentiating composition for ingestion in a mammal, in a pill form. The composition includes a first herbal extract having an element to synthesize a...
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6338857 |
Sustained release carbamazepine pharmaceutical composition free of food effect and a method for alleviating food effect in drug release
The invention provides a sustained release composition free of food effect comprising: (c) a core comprising carbamazepine; and (d) a functional coating comprising, based on the weight of the...
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6331316 |
Enteric coated pharmaceutical tablet and method of manufacturing
A high drug load enteric coated pharmaceutical composition is provided which includes a core in the form of a tablet and which is comprised of a medicament which is sensitive to a low pH...
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6328993 |
Oral administration form for an acid liable active proton pump inhibitor
Novel administration form for acid-labile active compounds are described. The novel administration forms have no enteric layers and are suitable for oral administration.
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6326028 |
Alginate and gellan gum as tablet coating
This invention relates to coatings employed to coat medicinal tablets. Such tablets include but are not limited to small pellet(s) of medication to be taken orally. In particular this invention...
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6326026 |
Subcoated simulated capsule-like medicament
A simulated capsule-like medicament comprising a subcoating of a mixture of a water-soluble, film-forming polymer, e.g. hydroxypropylmethyl cellulose and a hydrophobic plasticizer, e.g. castor oil,...
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6326360 |
Bubbling enteric coated preparations
An object of the present invention is to obtain an oral glycyrrhizin preparation not only manufacturable by a simple method but also having an excellent property of being absorbed from the...
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6322812 |
Pharmaceutical forms for the oral administration of mesna
The invention relates to pharmaceutical forms for oral administration in the form of tablets, film-coated tablets, pellets or granules comprising at least 88% of mesna, produced by granulation with...
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6322816 |
Fast-acting analgesic
A fast-acting analgesic comprises as analgesic substance ibuprofen in an adjuvant matrix with a porous structure and a density of greater than 1 and up to 2.5 g/cm 3 .
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6319512 |
Implants for controlled release of pharmaceutically active principles and method for making same
The present intention relates to an implant for the controlled release of at least one pharmaceutically active principle comprising a core containing at least one active principle and a sheath...
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6319683 |
Method and composition for controlling formaldehyde fixation by delayed quenching
A method and composition for quenching formaldehyde fixation of cell and tissue specimens. The composition includes a formaldehyde-reactive agent. The formaldehyde-reactive agent reacts with the...
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6319514 |
Analgesic and anti-inflammatory compositions comprising domperidone and methods of using same
The present invention provides a method for eliciting an onset hastened analgesic and anti-inflammatory response and combating nausea in acute migraine attacks. This method comprises administering...
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6316026 |
Method and apparatus for manufacturing tablet capable of quick disintegration in oral cavity
A method and an apparatus are adapted to manufacture a tablet capable of quick disintegration in the oral cavity that has a sufficiently large porosity and can be disintegrated in the oral cavity...
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6309668 |
Abuse resistant tablets
This invention relates to an abuse resistant tablet containing two or more layers having one or more drugs and one or more gelling agents and its preparation. The drug(s) and gelling agent(s) are...
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6306436 |
Stabilized, acid-free formulation for sustained release of bupropion hydrochloride
Stabilized bupropion hydrochloride pharmaceutical compositions are disclosed that are free of acid additives and provide for a sustained release of the bupropion hydrochloride. The particulate...
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6306900 |
Enteric coated pharmaceutical compositions
This invention provides a pharmaceutical composition comprising a mycophenolate salt, the composition being adapted to release mycophenolate in the upper part of the intestinal tract.
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6296874 |
Core formulation comprising troglitazone and abiguanide
This invention relates to a combination drug product comprising troglitazone, e.g. its hydrochloride, and a biguamide, e.g. metformin. In particular, the product comprises a core of metformin, at...
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6294200 |
Pharmaceutical tablet suitable to deliver the active substance in subsequent and predeterminable times
Pharmaceutical tablet, capable of delivering the active substance or the active substances, according to a predeterminable release profile, comprising a core with an external partial coating in...
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6284275 |
Controlled release tablet having a unitary core
A controlled release pharmaceutical tablet containing antihyperglycemic drug and a hypoglycemic drug that does not contain an expanding or gelling polymer layer and comprising a core containing the...
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6280770 |
Microemulsions as solid dosage forms for oral administration
Novel pharmaceutical compositions which improve the rate and/or extent of absorption of drugs are disclosed. The novel pharmaceutical compositions of the present invention comprise drug-containing...
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