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7612112 |
Methods of treatment using a gastric retained gabapentin dosage
A method of treatment for epilepsy and other disease states is described, which comprises the delivery of gabapentin in a gastric retained dosage form.
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7514100 |
Controlled release hydrocodone formulations
A solid oral controlled-release dosage form of hydrocodone is disclosed, the dosage form comprising an analgesically effective amount of hydrocodone or a pharmaceutically acceptable salt thereof,...
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7438927 |
Methods of treatment using a gastric retained gabapentin dosage
A method of treatment for epilepsy and other disease states is described, which comprises the delivery of gabapentin in a gastric retained dosage form.
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7419684 |
System and method for manufacturing oral osmotic drug delivery devices, and methods of administering same
A system and method for manufacturing oral osmotic drug delivery devices including the use of a mathematical model in deriving relationships between parameters used in manufacturing the devices for...
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7413751 |
Methods of treatment using a gastric retained losartan dosage
A method of treatment for hypertension and other disease states is described, which comprises the delivery of losartan in a gastric retained dosage form.
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7387792 |
Pharmaceutical composition for compressed annular tablet with molded triturate tablet for both intraoral and oral administration
New pharmaceutical compositions in unit dosage form are disclosed for both intraoral and oral administration to a patient, said unit dosage form configured to be placed intraorally of said patient,...
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7351695 |
Topiramate salts and compositions comprising and methods of making and using the same
The invention encompasses novel salts of topiramate, and pharmaceutically acceptable polymorphs, solvates, hydrates, dehydrates, co-crystals, anhydrous, or amorphous forms thereof, as well as...
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7329418 |
Pharmaceutical tablets having height greater than width
An immediate release compressed pharmaceutical tablet that has two or more segments and a top and a bottom and has a height that exceeds the width of the tablet. The height is measured vertically...
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7318935 |
Pharmaceutical tablets with active and inactive segments
An immediate release compressed pharmaceutical tablet that has two or more segments and a top and a bottom and has a height that exceeds the width of the tablet. The height is measured vertically...
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7300668 |
System for manufacturing controlled release dosage forms, such as a zero-order release profile dosage form manufactured by three-dimensional printing
The present invention includes controlled release dosage forms and methods of designing and manufacturing dosage forms to obtain specific release profiles, for example, zero-order release profiles,...
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7208176 |
Drug delivery device containing neuraminidase inhibitor and an H1 antagonist
The present invention provides a dual release solid dosage form containing a first composition that releases a neuraminidase inhibitor, such as oseltamivir, zanamivir, or peramivir, in a controlled...
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7147870 |
Osmotic device containing pseudoephedrine and an H1 antagonist
The present invention provides an osmotic device containing controlled release pseudoephedrine in the core in combination with a rapid release H1 antagonist in an external coat. A wide range of H1...
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7056726 |
membrane for encapsulation chamber of cells producing at least a biologically active substance and bioartificial organ comprising same
The invention concerns a semipermeable chamber for encapsulation of cells producing at least a biological substance of interest, characterised in that it consists of a porous polycarbonate...
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RE39069 |
Multi-layered osmotic device
The present invention provides a simple and improved multi-layered osmotic device ( 1 ) that is capable of delivering a first active agent in an outer lamina ( 2 ) to one environment of use and a...
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7011850 |
Dosage forms having a barrier layer to laser ablation
A dosage form for delivery of a therapeutic agent to a subject is described. The dosage form contains: (a) an outer wall defining an interior compartment; (b) within the interior compartment, a...
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7008641 |
Osmotic device containing venlafaxine and an anti-psychotic agent
The present invention provides an osmotic device containing controlled release venlafaxine in the core in combination with an anti-psychotic agent in a rapid release external coat. A wide range of...
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6994871 |
Once a day antihistamine and decongestant formulation
A controlled release pharmaceutical formulation for the administration of an antihistamine and decongestant to a patient wherein the formulation employs a compressed matrix core for the controlled...
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6991808 |
Process for the production of sustained release drug delivery devices
Disclosed is an improved sustained release drug delivery device and method of producing such device. The device comprises a drug core in an impermeable cup or impermeable coating layer that is...
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6976981 |
Osmotic delivery system with membrane plug retention mechanism
An osmotic delivery system has a membrane plug retention mechanism which can also be used to control the delivery rate of a beneficial agent from the osmotic delivery system. The osmotic delivery...
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6974591 |
Method for producing a controlled-release preparation
The invention concerns a method for producing a controlled-release pharmaceutical preparation with a particle-containing coating, the coating being derived from an aqueous dispersion of a...
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6964781 |
Sustained release drug delivery devices with prefabricated permeable plugs
The present invention is directed to an improved sustained release drug delivery device comprising a drug core, a unitary cup, and a prefabricated permeable plug.
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6964780 |
Controlled-release pharmaceutical formulations
The invention provides controlled-release formulations for oral administration containing a cGMP PDE-5 inhibitor. The formulations are useful, inter alia, in the treatment or prevention of sexual...
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6899896 |
Hydrogel-driven layered drug dosage form
A controlled release dosage form for sertraline has a core comprising a sertraline-containing composition and a water-swellable composition wherein the water-swellable composition is in a separate...
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6893646 |
Coated cosmetic powder
The present invention refers to a cosmetic powder whose coating includes polymers or co-polymer belonging to the Poly Alpha Hydroxi Acids family, to a cosmetic composition that contains it and to...
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6890518 |
Compositions of chemically modified insulin
The present invention provides active, hydrophilic polymer-modified derivatives of insulin. The insulin derivatives of the invention are, in one aspect, suitable for delivery to the lung and...
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6855334 |
Controlled delivery of active agents
Controlled release of active agents from sustained release push delivery devices having high drug loading are described wherein residual drug content in the device is minimized by the utilization...
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6838093 |
System for osmotic delivery of pharmaceutically active agents
An osmotic system for delivering a pharmaceutically active agent which comprises a core portion, a layer portion enclosing the core portion, and a semipermeable wall portion enclosing the core...
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6814979 |
Osmotic drug delivery system
Disclosed is an osmotic pharmaceutical delivery system comprising (a) a semi-permeable wall that maintains its integrity during pharmaceutical delivery and which has at least one passage...
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6787156 |
Controlled release composition
A composition for controlled delivery of at least one active substance into an aqueous medium by erosion at a preprogrammed rate of at least one surface of the composition, comprising the active...
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6773721 |
Osmotic caplet
An osmotic caplet is disclosed comprising an osmotic caplet exit for delivering a preselected dose of drug to a patient in need of therapy.
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6770297 |
Controlled release delivery system of solid dosage form
This invention relates to a controlled release delivery system of solid dosage form with a plurality of controls on the release of the active ingredient or ingredients.
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6764697 |
System for delaying drug delivery up to seven hours
A dosage form is disclosed comprising means for delaying the delivery of drug from the dosage form following the administration of the dosage form to a patient in need of drug therapy.
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6753011 |
Combined diffusion/osmotic pumping drug delivery system
Delivery devices capable of delivering one or more active substances by diffusion through plural micropores in the membrane ( 4 ) or by osmotic pumping through one or more preformed passageways ( 5...
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6730321 |
Press coated, pulsatile drug delivery system suitable for oral administration
A press-coated tablet suitable for oral administration, comprising an immediate-release compartment comprising a compressed blend of an active agent. The immediate-release compartment has a...
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6719751 |
Osmotic dosage form composed of an extruded polymer tube form
A dosage form manufactured from an extruded polymer tube and method for manufacturing the dosage form are disclosed. The dosage form is preferably an osmotic dosage form and includes a therapeutic...
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6706282 |
Controlled delivery of phenoxyethyl-substituted 1,2,4-triazolones
Dosage forms and methods for the controlled release of antidepressives, such as exemplified by phenoxyethyl substituted-1,2,4-triazolones, as a suspension or a slurry over a prolonged period of...
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6702803 |
Multi-step drug dosage forms
Controlled release, multi-step drug dosage forms comprising a plurality of dose units and a plurality of separators that control release of drug from the dose units. In one embodiment, a dose unit...
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6689373 |
Devices and methods for pain management
The invention features devices and methods for the systemic delivery of fentanyl or a fentanyl congener (e.g., sufentanil) to treat pain. In the present invention, a drug formulation comprising...
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6669957 |
Galenic formulations fast disintegrating in the mouth and method for preparing same
The invention relates to pharmaceutical dosage forms with rapid disintegration in the mouth and to their process of preparation. These pharmaceutical dosage forms comprise at least one active...
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6667058 |
Oral forms of administration containing solid flupirtine with controlled release of active substance
Pharmaceutical dosage units containing flupirtine or a pharmaceutically acceptable salt of flupirtine with controlled release of active substance using a delayed-action or controlled-release...
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6663896 |
Delayed release aspirin for vascular obstruction prophylaxis
A method and controlled release oral unit dosage form of acetylsalicylic acid (aspirin) delays the release of the drug until a predetermined time interval after ingestion. This enables the drug to...
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6649187 |
Use of polyalkylamine polymers in controlled release devices
The invention provides a method and device for administering an amine drug, such as...
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6641839 |
Pharmaceutical formulations for preventing drug tolerance
Isosorbide mononitrate formulations and methods of treatment are disclosed. The formulations and treatments provide for subtherapeutic levels of the mononitrate in a washout period to prevent...
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6635281 |
Gastric retaining oral liquid dosage form
The present invention is directed to an active agent dosage form which is adapted for retention in the stomach and useful for the prolonged delivery of a liquid, active agent formulation to a fluid...
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6632451 |
Delayed total release two pulse gastrointestinal drug delivery system
A two pulse gastrointestinal delivery system is provided. The system comprises a desired agent in combination with a swellable core material, the core being surrounded by an inner coat of a...
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6630165 |
Methods for providing effective reboxetine therapy with once-a-day dosing
Dosage forms and methods for providing sustained release of reboxetine are provided. The sustained release dosage forms provide therapeutically effective average steady-state plasma reboxetine...
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6613357 |
Osmotic device containing pseudoephedrine and an H1 antagonist
The present invention provides an osmotic device containing controlled release pseudoephedrine in the core in combination with a rapid release H1 antagonist in an external coat. A wide range of H1...
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6605302 |
Drug delivery device containing oseltamivir and an H1 antagonist
The present invention provides a dual release solid dosage form containing a first composition that releases oseltamivir in a controlled manner and a second composition that releases an H1...
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6596314 |
Controlled release liquid active agent formulation dosage forms
Controlled release of liquid, active agent formulations is provided by dispersing porous particles containing the liquid active agent formulation in osmotic, push-layer dosage forms. The dosage...
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6572582 |
Mixing system for an active agent delivery device
The present invention is directed to a mixing system for an active agent delivery device. The device comprises an elongate tubular member having first and second ends and a mixing system. The...
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