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Document Title |
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5391381 |
Dispenser capable of delivering plurality of drug units
A dispenser for use in a fluid environment which is capable of delivery of a plurality of discrete drug-containing units in any desired delivery pattern or profile.
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5387420 |
Morphine-containing efferverscent composition
In an effervescent formulation containing morphine, inclusion of the morphine in the basic component gives superior storage stability.
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5380532 |
Process for the preparation of medication in the form of pearls
Process for the preparation of pearls based on a pharmaceutical active substance exhibiting an indefinite crystallization point. The said active substance is mixed in molten form with a...
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5378475 |
Sustained release drug delivery devices
A method and device for treating a mammalian organism to obtain a desired local or systemic physiological or pharmacological effect is provided. The method includes administering a sustained...
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5376383 |
Method for enhancing the lowering of plasma-cholesterol levels
The instant invention is directed to a method for enhancing the lowering of plasma cholesterol level in a subject in need thereof which comprises the time-controlled administration of a nontoxic...
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5368863 |
Long-term delivery device with early startup
The present invention is directed to an improvement in a delivery device, the device comprising a wall that surrounds an internal lumen or compartment which contains a beneficial agent or...
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5366738 |
Controlled release drug dispersion delivery device
A device for the controlled delivery of a beneficial agent as a gelatinous dispersion consisting of (i) a core which contains a beneficial agent, a polymer which forms gelatinous microscopic...
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5358721 |
Antiviral therapy
A dosage form is disclosed for administering an antiviral drug to a patient in need of antiviral therapy.
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5348746 |
Method for administering drug
A dosage form is disclosed comprising means for lessening the tackiness and/or irritation of the components of the dosage form to mucosal tissue. The dosage form provides means for forming in the...
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5342627 |
Controlled release device
The invention relates to a device for the release of at least one active substance (e.g. ranitidine) into a fluid medium by dissolution comprising a covering, which is impermeable to the active...
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5340590 |
Delivery system with bilayer osmotic engine
A dispenser for use in a fluid environment which is capable of delivery of a plurality of discrete drug-containing units in any desired delivery pattern or profile.
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5338550 |
Stereoisomer therapy
A dosage form is disclosed comprising a first layer and a second layer. The first layer provides immediate therapy and comprises a drug stereoisomer and the second layer provides prolonged therapy...
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5330762 |
Tandospiaine antidepressive therapy
A dosage form is provided for administering a drug of the formula ##STR1## to a patient to produce an anxiolytic benefit in the patient.
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5328698 |
Method for rendering a substrate surface antithrombogenic and/or anti-infective
A shaped medical article of a polymeric substrate is extrusion coated with a composition which includes a bioactive agent dispersed in a matrix polymer. Preferred bioactive agents are temperature...
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5326571 |
Dosage forms comprising polymers comprising different molecular weights
A dosage form is disclosed comprising a wall surrounding a compartment, which comprises a first composition comprising a carboxymethylcellulose and a second composition comprising a higher...
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5324522 |
Sustained release thyroactive composition
Disclosed are sustained release dosage forms of liothyronine, in combination with normal or sustained release of thyroxine in a molar ratio of about 1 to 50:1, especially 5 to 20:1, useful in...
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5320616 |
Delivery system comprising first walled section and second walled section united by fusion, adhesion or telescopic engagement
A delivery system is disclosed for delivering a beneficial agent to an animal. The delivery system comprises a wall that surrounds a lumen, said wall comprising a composition that limits the...
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5318779 |
Drug-impregnated ceramic
A drug-impregnated ceramic to be embedded in a living body is disclosed, and includes a porous ceramic having pores with a pore size of 10 to 300 μm, a drug impregnating the porous ceramic via the...
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5312390 |
Osmotic device with delayed activation of drug delivery
The present invention is directed to a fluid-imbibing drug delivery device which is useful for the initial delayed delivery of an active agent formulation to a fluid environment of use, the initial...
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5312389 |
Osmotically driven syringe with programmable agent delivery
An osmotically driven syringe (20, 60) is disclosed which can be used to deliver a beneficial agent such as a drug, at varying pre-determined rates over multiple periods of time. The syringe (20,...
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5310561 |
Antiemetic therapy
A dosage form is disclosed comprising an antiemetic and antinausea drug for treating vomiting and nausea.
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5290271 |
Surgical implant and method for controlled release of chemotherapeutic agents
An implant and method is disclosed using microparticles to provide a controlled, sustained release, and improved cellular uptake, of chemotherapeutic agents.
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5284662 |
Oral osmotic system for slightly soluble active agents
An oral sustained release composition for slightly soluble pharmaceutically active agents comprising a core, a wall around said core, and a bore through said wall connecting said core and the...
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5284659 |
Encapsulated flavor with bioadhesive character in pressed mints and confections
A confectionery compressed tablet designed to dissolve in the oral cavity and containing a flavor ingredient intimately bound with a bioadhesive is disclosed. The flavor and bioadhesive composition...
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5273752 |
Controlled release dispenser comprising beneficial agent
A dispenser is disclosed for delivering a beneficial agent in a hydrophilic carrier formulation to an animal in a rate-controlled manner. The dispenser comprises (1) a semipermeable housing...
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5271946 |
Controlled release azelastine-containing pharmaceutical compositions
Azelastine-containing pharmaceutical compositions which provide controlled release of the active substance using a sustained release component. The compositions contain azelastine or a...
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5266332 |
Method for administering anti-Parkinson drug
A dosage form is disclosed comprising means for lessening the tackiness and/or irritation of the components of the dosage form to mucosal tissue. The dosage form provides means for forming in the...
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5254349 |
Process for lessening irritation caused by drug
A dosage form is disclosed comprising means for lessening the tackiness and/or irritation of the components of the dosage form to mucosal tissue. The dosage form provides means for forming in the...
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5252338 |
Therapy delayed
A dosage form is disclosed comprising means for delaying the delivery of drug from the dosage form following the administration of the dosage form to a patient in need of drug therapy.
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5246711 |
Dosage form for treating dysthymia
A dosage form is provided for administering a drug of the formula ##STR1## to a patient to produce an anxiolytic benefit in the patient.
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5246710 |
Dosage form for treating cyclothymia
A dosage form is provided for administering a drug of the formula ##STR1## to a patient to produce an anxiolytic benefit in the patient.
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5240713 |
Dual rate agent delivery device
The present invention is directed to a long-term dispensing device for the controlled delivery of a beneficial agent in a hydrophilic carrier, which device quickly and continuously delivers an...
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5238687 |
Delivery device with a protective sleeve
This invention relates to an active agent delivery device. More particularly, the invention relates to a delivery device that includes a sleeve to protect the delivery device from transient...
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5236689 |
Multi-unit delivery system
A dispenser for use in a fluid environment which is capable of delivery of a plurality of discrete drug-containing units in any desired delivery pattern or profile.
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5234694 |
Method for increasing feed efficiency in animals
This invention relates to an active agent delivery device. More particularly, the invention relates to a delivery device that includes a sleeve to protect the delivery device from transient...
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5232705 |
Dosage form for time-varying patterns of drug delivery
A dosage form is disclosed that comprises means inside the dosage form for providing a substantially drug-free interval before the dosage form delivers a drug from inside the dosage form. The...
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5229131 |
Pulsatile drug delivery system
A drug delivery system for administering a drug in controlled pulse doses to an aqueous environment in the body of a living being has one or more, and preferably less than ten, individual...
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5221536 |
Dosage form indicated for the management of abnormal posture, tremor and involuntary movement
A dosage form is disclosed comprising an anti-Parkinson's disease drug for administering to a patient in need of anti-Parkinson's disease therapy.
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5215753 |
Delivery system with thermoresponsive composition comprising means for controlling internal pressure
A dispensing device is disclosed for delivering a beneficial agent. The device comprises (1) a semipermeable housing defining a internal space, (2) an optional and presently preferred in the space,...
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5213808 |
Controlled release article with pulsatile release
An article for controlled delivery of an active substance into an aqueous phase has a first layer containing an active substance, and a second layer of a crystalline polymer matrix and a non-ionic...
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5206024 |
Density element for ruminal delivery device
A corrosion resistent density element for use in ruminal delivery devices which fragments upon contact with the blades in grinding machinery without damage to the blades. The density element has...
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5204116 |
Dosage form providing immediate therapy followed by prolonged therapy
A dosage form is disclosed comprising a first layer and a second layer. The first layer provides immediate therapy and comprises a drug stereoisomer and the second layer provides prolonged therapy...
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5200194 |
Oral osmotic device
An osmotic device (10) for delivering a beneficial drug, such as an anti-microbial drug, into the mouth of a human patient is disclosed. The device (10) has a size and shape adapting it to be...
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5200195 |
Process for improving dosage form delivery kinetics
A dosage form is disclosed comprising means for lessening the tackiness and/or irritation of the components of the dosage form to mucosal tissue. The dosage form provides means for forming in the...
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5200196 |
Improvement in pulsed drug therapy
A dosage form comprising (1) an immediately available dose of a beneficial drug followed by a timed delayed dose of drug, or (2) a timed delayed dose of drug.
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5200197 |
Contraceptive pill
An osmotic device is disclosed comprising an exterior coat comprising an estrogenic and a progestogenic steroid that are delivered immediately as a contraceptive pair for fertility regulation in a...
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5198229 |
Self-retaining gastrointestinal delivery device
The present invention is directed to a fluid-imbibing drug delivery device having a first, low density such that it floats in the stomach contents for a predetermined prolonged period of time,...
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5196202 |
Sustained release dosage form
A drug reservoir containing an active substance such as a drug is formed on an adhesive layer which can adhere to an oral mucosal membrane. A polymer, which does not dissolve with saliva, is...
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5192550 |
Dosage form for treating central nervous system disorders
A dosage form is disclosed comprising an anti-Parkinson's disease drug for administering to a patient in need of anti-Parkinson's disease therapy.
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5186942 |
Nicardipine therapy
A dosage form is disclosed comprising a member selected from the group consisting of nicardipine and its pharmaceutically acceptable salts for administering to a patient in need of cardio-vascular...
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