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6294200 |
Pharmaceutical tablet suitable to deliver the active substance in subsequent and predeterminable times
Pharmaceutical tablet, capable of delivering the active substance or the active substances, according to a predeterminable release profile, comprising a core with an external partial coating in...
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6287600 |
Stabilized pharmaceutical composition of a nonsteroidal anti-inflammatory agent and a prostaglandin
A pharmaceutical composition is provided for the oral administration of an NSAlD and a prostaglandin. The composition is a solid dosage form wherein the NSAID is enterically coated and the...
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6284274 |
Analgesic tablet compositions
An opiate analgesic composition and a non-opiate analgesic composition are disclosed for delivering an analgesic in either embodiment to a patient in need of relief from pain. The analgesics are...
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6277406 |
Easily processed tablet compositions
The invention deals with the use of low temperature and low humidity conditions during the storage and shaping of "flash-dose" tablet compositions. The compositions may be rendered substantially...
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6267986 |
Process for the preparation of a controlled drug delivery system containing pseudoephedrine and a long acting antihistamine
This invention relates to a process for the preparation of a controlled release pharmaceutical composition comprising two discrete zones wherein the first discrete zone comprises therapeutically...
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6264985 |
Laminated tablet with pointed core
A dry-coated tablet for controlled release of active substance, having an erodible core tablet (1) containing at least one active substance, and a substantially erosion-resistant shell consisting...
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6264974 |
Buccal and sublingual administration of physostigmine
Physostigmine, 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo[2,3-b] indol-5ol methylcarbamate, administered buccally or sublingually in non-sustained release dosage form provides extremely...
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6254886 |
Multilayer tablet
The invention relates to multilayer tablets which are constructed of two, three or more layers, one layer containing probiotic microorganisms, while the other layers contain foodstuff ingredients...
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6248355 |
Pharmaceutical composition containing an acid-labile omeprazole and process for its preparation
A composition, particularly adapted for oral administration, containing omeprazole, and a method for preparing the composition, are disclosed. The composition, being exempt of alkaline-reacting...
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6248760 |
Tablet giving rapid release of nicotine for transmucosal administration
A tablet for the transmucosal administration of nicotine. The nicotine is in one or more layers upon a non-nicotine containing matrix. The nicotine layers rapidly dissolve in the mouth. The...
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6248359 |
Multi-tablet oxybutynin system for treating incontinence
The present invention provides a simple multi-tablet system for the treatment of urinary incontinence with oxybutynin. Particular embodiments of the invention provide a first tablet that releases...
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6242004 |
Bioadhesive tablets
The invention relates to bioadhesive compounds in the form of multilayers and having at least one bioadhesive layer with the total charge of bioadhesive material wherein the bioadhesive layer is...
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6238699 |
Pharmaceutical formulations containing a combination of carbidopa and levidopa
An oral anti-Parkinson drug delivery system consisting of carbidopa and levodopa in immediate and sustained release compartments provides a significant clinical advantage over currently available...
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6238698 |
Oral preparation containing at least one active pharmaceutical substance in a matrix capable of swelling in an aqueous medium
An oral preparation, comprising at least one pharmaceutical active compound in a matrix which is swellable in aqueous medium, which is released from the matrix into the aqueous medium in a delayed...
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6238704 |
Sustained-release preparation utilizing thermal change and process for the production thereof
A sustained-release preparation which can release a highly water-soluble medicinally active ingredient over a long time and a process for the production thereof are provided. The preparation has a...
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6235311 |
Pharmaceutical composition containing a combination of a statin and aspirin and method
A pharmaceutical composition is provided which is useful for cholesterol lowering and reducing the risk of a myocardial infarction, which includes a statin, such as pravastatin, lovastatin,...
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6214379 |
Maximizing effectiveness of substances used to improve health and well being
The present disclosure relates to novel dosage forms, drug delivery regimens, methods and pharmaceutical compositions which optimize the therapeutic effects of active therapeutic substances through...
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6210712 |
Dosage form having first and second coats
A dosage form comprising a composition comprising a drug surrounded by a first coat and a second coat with an exit for administering the drug to a patient; and a method of using the dosage form are...
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6207191 |
Multi-stage drug delivery system
A drug delivery system (10) includes a first capsule half (12) having an inner chamber (16) containing a drug (18) therein. A plug (28) is disposed in a passageway (26) of the capsule half (12) for...
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6207190 |
Dosage forms for the treatment of the chronic glaucomas
Four interdependent functional groups of biofactors and biomolecules are identified and formulations are defined which are comprised of their members. The active agents are demonstrated to be...
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6197329 |
Anti-nausea compositions and methods
The present disclosure is directed to novel nutritional anti-nausea compositions, anti-emetic compositions, and methods of using same. The compositions provide improved relief from nausea and/or...
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6194000 |
Analgesic immediate and controlled release pharmaceutical composition
Disclosed is a method for the therapeutic treatment of pain related to wind up in a human or animal. The method of the invention is practiced by administering to the subject an effective amount of...
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6183778 |
Pharmaceutical tablet capable of liberating one or more drugs at different release rates
Pharmaceutical tablet consisting of a first layer containing one or more drugs with immediate or controlled release formulation, a second layer containing one or more drugs, either equal to or...
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6183845 |
Multiple layer softgel
A device, and a method for forming a softgel having multiple gelatin layers and softgels having multiple gelatin layers are disclosed. In particular there is provided a device for forming a gelatin...
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6183777 |
Controlled release tacrine dosage form
Disclosed is a controlled release tacrine dosage form, which comprises: (a) a core; (b) an inner active layer comprising tacrine and a binder; (c) a release-controlling layer comprising...
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6149940 |
Tablet with controlled release of alfuzosine chlorhydrate
Pharmaceutical tablet which consists of: a) a first layer having the property of swelling considerably and quickly on contact with aqueous biological fluids, the first layer being produced by...
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6136327 |
Stereospecific delivery of a drug using electrotransport
Preferential delivery via electrotransport of a preferred isomeric form of a pharmaceutically active chiral compound from a mixture of the isomeric forms of said compound is provided. A method of...
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6086919 |
Pharmaceutical composition containing the ace inhibitor ramipril and a dihydropyridine compound
The invention is directed to a pharmaceutical composition which is a combination of the ACE inhibitor ramipril and a calcium antagonist of one of the dihydropyridine type compounds felodipine,...
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6083533 |
Layered tablet for the controlled release of active substances
A layered tablet for the controlled release of active substances in a liquid medium comprising at least one active substance-containing, layered matrix with contact surfaces to the liquid medium...
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6066339 |
Oral morphine multiparticulate formulation
An oral morphine multiparticulate formulation for once-daily administration to a patient, comprising sustained release particles each having a core containing water soluble morphine and an osmotic...
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6056968 |
Pharmaceutical drug dosage forms providing different release rates
A pharmaceutical dosage form comprises, in one portion thereof, a substantially single (+)-enantiomer of a chiral drug other than verapamil and, in another, separate portion thereof, a...
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6042847 |
Three-phase pharmaceutical form with constant and controlled release of amorphous active ingredient for single daily application
Described is a novel three-phase pharmaceutical form with constant and controlled release of an amorphous active ingredient stabilized with polymers for a single daily peroral application, which is...
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6039974 |
Pharmaceutical composition for combination of piperidinoalkanol-decongestant
The present invention provides a pharmaceutical composition in the form of a bilayer tablet comprising, (a) a first discrete zone made with Formulation (A) which comprises, a therapeutically...
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6039975 |
Colon targeted delivery system
A novel delivery system for targeting drugs to the colon is herein described. The system is a tablet comprised of three parts: 1) an outer enteric coating, 2) an inner semi-permeable polymer...
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6036973 |
Therapy for neurological diseases
A dosage form is disclosed for administering 10 ng to 1200 mg tacrine to a patient in need of tacrine therapy.
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6033685 |
Tablet for the controlled release of active agents
The present invention provides a tablet for the controlled release of an active agent comprising (a) a matrix layer comprising an active agent embedded in a non-swelling, non-gelling hydrophobic...
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6027748 |
Pharmaceutical tablet, completely coated, for controlled release of active principles that present problems of bio-availability linked to gastro-intestinal absorption
Described herein is a particular type of pharmaceutical tablet, for oral use, which is formed by one or more layers, and is specifically designed for controlled release of active principles that...
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6022554 |
Polymeric microporous film coated subcutaneous implant
This invention relates to coating formulations for coating sustained-release drug implants. The coating formulations are capable of formulations are capable of forming a porous film coat over a...
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6001391 |
Process for producing solid drug forms having at least two phases
A process for producing solid combination tablets which have at least two phases comprises molding a melt of a polymeric binder with or without at least one active ingredient, there being at least...
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5976571 |
Method for making a multi-stage drug delivery system
A drug delivery system (10) includes a first capsule half (12) having an inner chamber (16) for containing a drug (18) therein. A plug (28) is disposed in a passageway (26) of the capsule half (12)...
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5938654 |
Osmotic device for delayed delivery of agent
A dispenser for use in a fluid environment of use which is capable of the delivery of one or a plurality of discrete active agent-containing units in any desired delivery pattern or profile. It...
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5914131 |
Hydromorphone therapy
A hydromorphone composition, a hydromorphone dosage form and a method for administering hydromorphone are disclosed, indicated for the management of pain.
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5908638 |
Pharmaceutical compositions of conjugated estrogens and methods for their use
This invention relates to novel pharmaceutical compositions and methods for their preparation containing conjugated estrogens for the treatment of peri-menopausal, menopausal and post-menopausal...
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5897879 |
Sustained-release pharmaceutical system for the delivery of antioxidants
The invention relates to a sustained-release pharmaceutical delivery system for the administration of an antioxidant drug to a patient in need of such drug, wherein said delivery system comprises...
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5885616 |
Sustained release drug delivery system suitable for oral administration
A single bead drug delivery system suitable for oral administration with multiply layered drug and polymer compartments can provide a two-step release of active agent to facilitate an immediate yet...
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5882715 |
Method of preparing an oral preparation provided on the outer side with an enteric coating, as well as an oral preparation obtained by the method
A method of preparing an oral preparation, especially in the form of hard gelatin capsules, tablets or pellets, for use by the administration of drugs or supplementary nutrients for human beings or...
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5874107 |
Sustained release tablet containing diclofenac-Na and methylhydroxypropyl-cellulose as a sustained release agent
The invention relates to a sustained release tablet containing diclofenac-Na as active material and methylhydroxypropylcellulose as sustained release agent.
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5869096 |
Oral osmotic device with hydrogel driving member
An osmotic device (10) for delivering a beneficial drug, such as an anti-fungal, into the mouth of a human patient is disclosed. The device (10) has a size and shape adapting it to be comfortably...
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5866164 |
Composition and dosage form comprising opioid antagonist
A composition of matter is disclosed and claimed comprising an opioid antagonist and a high molecular weight poly(alkylene) or a poly(carboxymethylcellulose). A dosage form is disclosed and claimed...
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5849330 |
Controlled release pharmaceutical
The invention relates to long-acting pharmaceutical compositions from which the release of the active compound increases exponentially, and to a process for their preparation. The composition,...
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