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5110605 |
Calcium polycarbophil-alginate controlled release composition and method
A polymeric complex composition comprising a reaction complex formed by the interaction of a polycarbophil component with alginic acid or a salt thereof, said interaction being performed in the...
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5102666 |
Calcium polycarbophil controlled release composition and method
Controlled release compositions comprising calcium polycarbophil and an active agent selected from the group consisting of medicinal agents, breath fresheners, and flavors, and a method of...
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5096717 |
Double-coated granules of disodium pamidronate
The invention relates to an advantageous oral administration from the disodium pamidronate in capsules. These capsules are filled with double-coated granules. The inner coating is hydrophilic and...
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5091175 |
Pharmaceutical composition containing bile acid sequestrant enclosed in a size-exclusion membrane
A pharmaceutical composition useful for treating hypercholesterolemia comprising a bile acid sequestrant resin such as cholestyramine and cholestipol maintained in a semipermeable water-insoluble...
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5087455 |
Hollow granular medicine and its preparation
A granular medicine with slow drug-release characteristics that is sufficiently absorbed in the intestines, in which the granular medicine has a hollow spherical structure, a drug is dispersed in...
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5087454 |
Ibuprofen tablet
Ibuprofen tablets/caplets formed by wet granulation of the ibuprofen characterized by a dissolution profile maintained stable on aging by incorporating croscarmellose sodium separately into the wet...
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5085865 |
Sustained release pharmaceutical preparations containing an analgesic and a decongestant
An orally administrable sustained-release pharmaceutical tablet having at least two layers, which are directly compressible, is disclosed. The first layer, an immediate-release layer, contains an...
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5082669 |
Rapid-releasing oral particle pharmaceutical preparation with unpleasant taste masked
A rapid-releasing oral particle pharmaceutical preparation with its unpleasant taste masked comprising a core and a film layer coating the core, the core at least containing a drug having an...
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5075114 |
Taste masking and sustained release coatings for pharmaceuticals
Chewable medicament tablets are made from coated granules of a medicament wherein the coating on said granules comprises a blend of cellulose actate and/or cellulose acetate butyrate and...
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5073380 |
Oral sustained release pharmaceutical formulation and process
A pharmaceutical sustained release tablet or tablet layer is formed by making a wet granulation, using povidone (PVP) in water or alcohol-water as the granulating fluid which is mixed with a...
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5073384 |
Maltodextrin/defoaming composition combinate
A consumable antigas or antiflatulent composition is produced by combining a water soluble agglomerated maltodextrin and a fluid, nonaqueous, defoaming or antifoaming composition such as...
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5069910 |
Dispersible cimetidine tablets
There are described novel dispersible cimetidine tablets containing 30 to 90% by weight of one of the polymorphous modifications of cimetidine A, B or C, 5 to 55% by weight of one or more...
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5069911 |
Pharmaceutical 9,10-dihydrogenated ergot alkaloid containing compositions
A controlled release formulation for oral administration comprising a 9,10-dihydro ergot alkaloid, a pharmaceutically acceptable hydrophilic swelling substance and a pharmaceutically...
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5059595 |
Pharmaceutical compositions containing 5-methyltetrahydrofolic acid, 5-formyltetrahydrofolic acid and their pharmaceutically acceptable salts in controlled-release form active in the therapy of organic mental disturbances
This invention relates to pharmaceutical compositions containing 5-methyltetrahydrofolic acid, 5-formyltetrahydrofolic acid and their pharmaceutical acceptable salts in controlled-release form...
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5047246 |
Direct compression cyclophosphamide tablet
A directly compressible pharmaceutical composition comprising cyclophosphamide and a partially or fully pregelatinized starch is disclosed. The pharmaceutical composition, when directly compressed...
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5037658 |
Direct dry compressible acetaminophen composition
This invention relates to analgesic composition and more particularly, to a directly dry compressible composition comprising at least about 70% by dry weight of the composition of acetaminophen and...
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5030447 |
Pharmaceutical compositions having good stability
A pharmaceutical compositions is provided which has excellent stability, when dispersed in water has a pH of at least about 9, and includes a medicament which is sensitive to a low pH environment...
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5030455 |
Sustained-release drug preparation
A sustained-release drug preparation comprises a water-soluble drug, a lipidic substance and an oil as its essential components. The drug level in the blood is sustained at a preferable...
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5028433 |
Readily absorbable drug formulation of NB-818
A readily absorbable drug formulation obtained by incorporating to a water-soluble or enteric polymer, both a nonionic surfactant and (±)-2-carbamoyloxymethyl-4-...
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5024842 |
Annealed coats
A dosage form is disclosed comprising a coat that surrounds a drug. The coat comprises a subcoat and an overcoat thermally annealed to provide a single unit coat around the drug.
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5019396 |
Delivery dispenser for treating cardiac arrhythmias
A dosage form is disclosed comprising a first composition comprising two different polyethylene oxide osmopolymers for delivering a drug at a controlled rate over time.
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5015480 |
Film coating formulations
Aqueous diffusion coating formulations suitable for use on pharmaceutical dosage forms comprising an admixture of an insoluble polymer component of a copolymer of ethylacrylate and...
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5013728 |
Composition for treating osteoporosis and hormonal imbalance
A medication for providing fluoride ion for the prevention and treatment of bone loss disease, together with an estrogen-containing substance for not only treating hormonal imbalance but to obtain...
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5009897 |
Pharmaceutical granules and tablets made therefrom
A pharmaceutical granule comprising a core of active pharmaceutical agent and a coating of a polymer/microcrystalline cellulose is provided. These granules permit superior tableting of...
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5009887 |
Deodorant composition in the form of a gel
A new deodorant composition in the form of gel is now provided, which comprises 2% to 30% by weight of sodium polyacrylate or ammonium polyacrylate having a molecular weight of form 40,000 to...
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5004613 |
Oral sustained release pharmaceutical formulation and process
A pharmaceutical sustained release tablet or tablet layer is formed by making a wet granulation, using povidone (PVP) in water or alcohol-water as the granulating fluid which is mixed with a...
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5002774 |
Sustained release pharmaceutical tablet
A sustained release solid composition for delivering an amount of a pharmaceutical material, prticularly magnesium lactate, to the gastro-intestinal tract comprising: an active pharmaceutical...
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4996220 |
Method of producing a clathrate compound
A clathrate compound is produced if a powdery host compound which reacts with a microbicide to form the clathrate compound is added into an aqueous solution of the microbicide. If the microbicide...
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4990335 |
Use of vinyl alcohol homopolymer and copolymers for tableting active materials
Method of making tablets for active ingredient delivery by compressing a mixture of active ingredient and granular, high viscosity, fully hydrolyzed polyvinyl alcohol or copolymer of vinyl alcohol...
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4983400 |
Controlled release combination of carbidopa/levodopa
A matrix or monolithic drug delivery system for the controlled release of carbidopa and levodopa consists of the two drugs uniformly dispersed in a polymer vehicle at a concentration that is...
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4975283 |
Stabilized enteric coated aspirin granules and process for preparation
A stabilized enteric coated aspirin granule product prepared by commingling the enteric coated aspirin granules with glutamic acid hydrochloride.
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4970078 |
Crosslinked carboxymethyguar tablet disintegrant
Tablets containing 1-2% by weight carboxymethylguar as a disintegrant are equivalent to tablets containing sodium carboxymethylcellulose in medicant release. These tablets can be made at a lower...
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4970075 |
Controlled release bases for pharmaceuticals
The release of therapeutically active agents from controlled release bases is extended by using a combination of a higher aliphatic alcohol and an acrylic resin as the base material.
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4968509 |
Oral sustained release acetaminophen formulation and process
An acetaminophen-sustained release tablet or tablet layer is formed by making a wet granulation, using Povidone (PVP) in water or alcohol-water as the granulating fluid which is mixed with...
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4968508 |
Sustained release matrix
This invention provides a matrix composition for sustained drug delivery which is comprised of an active agent, a hydrophilic polymer and an enteric polymer. The enteric polymer is impermeable to...
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4966770 |
Prednisone microencapsulated granules
The invention disclosed is prednisone microencapsulated granules with activity densities greater than about 0.030 g/ml. These granules are unusually small, having diameters less than about 1000...
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4966768 |
Sustained release etodolac
A sustained release dosage form of etodolac is provided which is a tablet having as essential components etodolac, hydroxyproplymethylcellulose, ethylcellulose and a release rate modifying agent...
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4966772 |
DHP delayed release preparation
A solid medicament preparation having long-lasting action containing a sparingly soluble dihydropyridine active compound of the Formula (I) ##STR1## the preparation having a core-coating...
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4954349 |
Oral magnesium and potassium compositions and use
Solid oral composition for the treatment or prophylaxis of potassium and magnesium deficiency in skeletal and cardiac muscle containing about 3 to about 50 milliequivalent bioavailable potassium,...
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4942040 |
Pharmaceutical preparation and a process for its preparation
Preparation giving a controlled and extended release of both a dihydropyridine, e.g. felodipine and a β-adrenoreceptor antagonist, namely metoprolol as well as a method for the manufacture of the...
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4937080 |
Granular product (I)
The present invention relates to a granular product comprised of a solid product which has been provided with a coating of a melt of itself, as well as a process for the preparation of the granular...
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4927639 |
Modified release gemfibrozil composition
A disintegratable formulation of gemfibrozil providing both immediate and sustained release and comprises a tablet compressed from a mixture of a first and second granulation, and a disintegration...
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4925674 |
Amoxicillin microencapsulated granules
The invention disclosed is amoxicillin microencapsulated granules with activity densities greater than about 0.200 g/ml. These granules are unusually small having diameters less than about 1000...
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4925676 |
Extended release gemfibrozil composition
A disintegratable gemfibrozil tablet providing both immediate and enteric release is compressed from a mixture of a first granulation of gemfibrozil with at least one acid-disintegratable binder...
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4925672 |
Products containing a calcium antagonist and a lipid-lowering agent
Combinations of calcium antagonists and lipid-lowering agents are suitable for controlling diseases.
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4925675 |
Erythromycin microencapsulated granules
The invention disclosed is erythromycin microencapsulated granules activity densities greater than about 0.300 g/ml. These granules are unusually small having diameters less than about 1000...
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4917899 |
Controlled absorption diltiazem formulation
A diltiazem pellet formulation for oral administration comprises a core of diltiazem or a pharmaceutically acceptable salt thereof in association with an organic acid and a lubricant, and a...
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4910023 |
Drug in combination with flavor masking agent and method for making same
According to this invention various hygroscopic malflavored drugs can be proceeded by a unique wet granulation process wherein a slurry of the drug in water is dried in combination with colloidal...
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4904478 |
Slow-release sodium fluoride tablet and method for treatment of osteoporosis
A novel slow-release sodium fluoride preparation and its use. Such slow-release sodium preparation comprises carnauba wax and talc and may be used to provide a safe but effective level of fluoride...
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4902516 |
Binder-free granules with delayed release of the active compound
Binder-free granules for oral and parenteral administration with delayed release of the active compound, consisting of a pharmaceutical active compound or granules thereof and a coating of 1 to 20%...
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