Matches 301 - 350 out of 510 < 1 2 3 4 5 6 7 8 9 10 11 >
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5334393 Sustained-release tablet based on isosorbide 5-mononitrate and process for preparing it  
The present invention relates to a sustained-release tablet, characterized in that it comprises as active principle isosorbide 5-mononitrate (5-ISMN) in the form of a powder having a particle size...
5330761 Bioadhesive tablet for non-systemic use products  
The present invention relates to a controlled release bioadhesive tablet which includes a locally active agent, a heterodisperse gum matrix, and a pharmaceutically acceptable diluent. In certain...
5326572 Freeze-dried polymer dispersions and the use thereof in preparing sustained-release pharmaceutical compositions  
Freeze-dried polymer latices, which can be reconstituted in water to give aqueous polymer dispersions having high polymer solids content, are described. The reconstituted polymer dispersions are...
5324523 Controlled release pharmaceutical preparation and process for preparing same  
Controlled release pharmaceutical preparations are prepared by homogenizing an organic or inorganic pharmaceutical active substance such as an opium alkaloid or its salts, an opium antagonist or...
5314697 Stable extended release oral dosage composition comprising loratadine and pseudoephedrine  
A film-coated extended release oral dosage composition containing the nasal decongestant pseudoephedrine sulfate in a unique polymer matrix core and a film-coating on such core containing the...
5310561 Antiemetic therapy  
A dosage form is disclosed comprising an antiemetic and antinausea drug for treating vomiting and nausea.
5292518 Prolonged-release drug tablet formulations  
A prolonged-release unit dosage formulation or pharmaceutical composition, preferably in tablet form, is described. The composition consists essentially of a gel-forming dietary fiber, a...
5283065 Controlled release pharmaceutical compositions from spherical granules in tabletted oral dosage unit form  
A controlled release pharmaceutical composition in oral dosage unit form comprising a tablet comprising a therapeutically effective number of active spherical granules comprising an effective...
5275819 Drug loaded pollen grains with an outer coating for pulsed delivery  
A pulsating release composition comprising natural microspheres, such as pollen grains or spores, into which are loaded a biologically active is subsequently releasable therefrom in a predetermined...
5275824 Therapeutic compositions with controlled release of medicaments supported on crosslinked polymers and coated with polymer films, and their preparation process  
The described therapeutic compositions with controlled release of medicaments comprise a medicament loaded onto particles of a crosslinked non-ionic polymer insoluble but swellable in water, using...
5273758 Directly compressible polyethylene oxide vehicle for preparing therapeutic dosage forms  
Polyethylene oxide polymer is employed as a directly compressible binder matrix for therapeutically active dosage forms. Advantageously, the polyethylene oxide has an adjustable rate control effect...
5268182 Sustained-release drug dosage units of terazosin  
A sustained-release coating composition is described that contains an ethylcellulose and/or a methacrylic methylester together with a plasticizer and a detackifying agent. Sized drug granules are...
5268181 Method of using niacin to control nocturnal cholesterol synthesis  
The invention provides a therapeutic method to treat hyperlipidemia by administering to a human patient a single daily dose of a prolonged release dosage form of niacin, so that nocturnal...
5262169 Tablets and granulates containing mesna as active substance  
A granulate containing mesna is made by granulating mesna in the presence of an alcohol, acetone or a mixture of one of these with water. The granulate may be converted to tablets, along with other...
5248700 Active agent containing solid structures for prolonged release of active agents  
A solid mixture of a degradable polymer (B) in which an active agent loaded microporous powder or granulate form polymer (A) is uniformly dispersed. The active agent loaded polymer (A) is...
5234691 Sustained-release prepararation of basic medical agent hydrochloride  
A preparation obtained by coating granules containing both a basic medical agent hydrochloride (e.g. allotinolol hydrochloride) and a polyanion the particles of which are present in the form of a...
5217719 Surface-treated sodium bicarbonate particle and molded preparation thereof  
Surface-treated sodium bicarbonate particles, the surfaces of which are coated with sodium carbonate or its double salt, are disclosed. Heat treatment or irradiation with micro waves o infrared...
5211958 Pharmaceutical composition and process for its preparation  
A multi-purpose pharmaceutical tablet which can either be readily swallowed or dissolved in water to give a dispersion, comprising a tetracycline, microcrystalline cellulose or microfine cellulose,...
5211957 Solid rapidly disintegrating dosage form  
The invention relates to a solid, rapidly disintegrating dosage form in the form of effervescent tablets for producing an aqueous suspension of diclofenac for peroral administration. The dosage...
5202159 Preparation method of microdispersed tablet formulation of spray-dried sodium diclofenac enteric-coated microcapsules  
A preparation method of sodium diclofenac enteric-coated microcapsules by spray drying technique comprising the steps of (a) dissolving sodium diclofenac in an appropriate amount of distilled...
5200193 Pharmaceutical sustained release matrix and process  
A pharmaceutical sustained release homogeneous tablet or homogeneous tablet layer is formed by making a wet granulation using povidone (PVP) in alcohol as the granulating fluid which is mixed with...
5198228 Direct dry compressible acetaminophen tablet  
This invention relates to an analgesic composition and more particularly, to a directly dry compressible composition comprising at least about 70% by dry weight of the composition of acetaminophen...
5196203 Theophylline dosage form  
A pH-dependent sustained release pharmaceutical pellet composition and a method of administering the same to a patient at a predetermined dosage and interval, said pellet composition comprising: a...
5188841 Sustained release pharmaceutical formulations  
The invention provides a sustained release formulation of ketoprofen comprising granules each of which comprises a core comprising ketoprofen and microcrystalline cellulose and a coating comprising...
5185152 Method and apparatus for controlled release drug delivery to the cornea and anterior chamber of the eye  
A method and device for delivering a drug to the cornea and anterior chamber of an eye are disclosed. A drug is entrapped in microspheres of poly(lactic acid), poly(glycolic acid), a copolymer of...
5185159 Pharmaceutical composition based on valproic acid and a process for preparing it  
New pharmaceutical composition based on valproic acid and one of the pharmaceutically acceptable salts thereof, obtained by a new galenic preparation process which makes it possible to improve and...
5169639 Controlled release verapamil tablets  
Controlled release verapamil tablets are disclosed. The tablets include an excipient having a hydrophilic material, preferably containing a mixture of xanthan gum/locust bean gum, and an inert...
5164380 Process for preparing piroxicam/cyclodextrin complexes, the products obtained and their pharmaceutical compositions  
A process for preparing complexes of piroxicam with cyclodextrins in which the two components in the powder state are premixed and then co-ground in a high energy mill in the presence of steam. The...
5160742 System for delivering an active substance for sustained release  
A system for delivering an active substance has sustained release of the active substance in the intestinal tract. This delivery system is especially useful for an active substance such as a...
5160469 Manufacture of pellets of xanthine derivatives  
A process for the manufacture of pellets which are composed of xanthine derivatives and are predominantly spherical, have a particle size in the range of 0.3 to 4 mm and have a bulk density above...
5158777 Captopril formulation providing increased duration of activity  
A formulation comprising captopril within an enteric or delayed release coated pH stable core combined with additional captopril that is available for immediate release following administration.
5153002 Biocompatible gradient controlled release implant  
A biocompatible and/or biodegradable implant for the substantially constant release, by diffusion, of a therapeutic agent in the outside medium at the site of implant which comprises a body...
5151273 Delayed-release pharmaceutical preparation  
Delayed-release tablets are formed by incorporating hemicellulose and a matrix-forming adjuvant which does not disintegrate in a pharmaceutical dosage form containing the active substance or...
5147646 Hydrogel containing envelopes  
An envelope having flexible water-permeable or porous walls contains a quantity of particulate water-insoluble hydrogel. The quantity of hydrogel in the envelope is such that, when the hydrogel is...
5137669 Manufacture of partially fused peptide pellet  
A bioerodible pellet capable of administering an even and continuous dose of a peptide over a period of up to a year, when subcutaneously implanted, is provided. The bioerodible implant is a...
5135757 Compressible sustained release solid dosage forms  
A free-flowing directly compressible granulation useful as a slow release pharmaceutical excipient is disclosed. The excipient includes a hydrodrophilic matrix which includes heteropolysaccharide...
5132295 Alginate-based verapamil-containing depot drug form  
An alginate-based depot drug form for which the rate of release of the active substance in vitro can be adjusted very precisely is described.
5132116 Tablets of the hydrophilic matrix type based on salbutamol and a process for their preparation  
The present invention relates to tablets of the type which contain a homogeneous dispersion of an active principle based on salbutamol or on one of its derivatives in a hydrophilic matrix,...
RE33994 Pharmaceutical delivery system  
A composition for use in an aqueous environment which comprise comprises a formulation containing a water-soluble pharmaceutically beneficial agent, a water-insoluble, water-permeable film...
5130140 Method of making direct dry compressible acetaminophen composition  
This invention relates to an analgesic composition and more particularly, to a directly dry compressible composition comprising at least about 70% by dry weight of the composition of acetaminophen...
5128143 Sustained release excipient and tablet formulation  
A slow release pharmaceutical excipient of an inert diluent and a hydrodrophilic material including xanthan gum and a galactomannan gum capable of cross-linking the xanthan gum in the presence of...
5128142 Sustained release drug delivery system  
A controlled release formulation comprising an adsorbate of a mixture of a pharmaceutically useful active ingredient and an inactive substance adsorbed on a cross-linked polymer. The inactive...
5126145 Controlled release tablet containing water soluble medicament  
A sustained or controlled release tablet is disclosed. The tablet comprises a water soluble medicament, a hydroxypropyl methylcellulose having sustaining action, a pharmaceutical binding agent, and...
5118528 Process for the preparation of dispersible colloidal systems of a substance in the form of nanoparticles  
The process according to the invention comprises: (1) the preparation of a liquid phase consisting essentially of a solution of the substance in a solvent or in a mixture of solvents to which may...
5116619 Vaginal progesterone tablet  
A vaginal progesterone suppository is provided in the form of a tablet which delivers biologically effective amounts of progesterone for at least about 48 hours, and blood amounts above basal...
5108759 Endothelial envelopment drug carriers  
This application describes the preparation and in vivo testing of surface coatings and matrix materials, which when applied to or caused to comprise the carriers for drugs and diagnostic agents,...
5091175 Pharmaceutical composition containing bile acid sequestrant enclosed in a size-exclusion membrane  
A pharmaceutical composition useful for treating hypercholesterolemia comprising a bile acid sequestrant resin such as cholestyramine and cholestipol maintained in a semipermeable water-insoluble...
5085865 Sustained release pharmaceutical preparations containing an analgesic and a decongestant  
An orally administrable sustained-release pharmaceutical tablet having at least two layers, which are directly compressible, is disclosed. The first layer, an immediate-release layer, contains an...
5082667 Solid pharmaceutical dosage in tablet triturate form and method of producing same  
A solid pharmaceutical dosage in tablet triturate form is disclosed. The tablet triturate form includes a cementatory network constituted by a water-soluble but ethanol-insoluble carbohydrate. Also...
5080907 Pharmaceutical preparations containing non-steroidal anti-inflammatory agents  
Pharmaceutical preparations for oral administration are disclosed which comprise (a) an acidic non-steroidal anti-inflammatory agent having the mean particle size of about 100 μm or less and (b) a...
Matches 301 - 350 out of 510 < 1 2 3 4 5 6 7 8 9 10 11 >