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6630162 Pharmaceutical formulation and its use  
The invention relates to a pharmaceutical formulation containing tolterodine or a tolterodine-related compound, or a pharmacologically acceptable salt thereof, as active ingredient, in which the...
6627223 Timed pulsatile drug delivery systems  
A pharmaceutical dosage form such as a capsule capable of delivering therapeutic agents into the body in a time-controlled or position-controlled pulsatile release fashion, is composed of a...
6627222 Amoxicillin-dicloxacillin antibiotic composition  
An antibiotic product for delivering at least Amoxicillin or dicloxacillin that is comprised of three dosage forms with different release profiles with each of Amoxicillin and dicloxacillin being...
6623756 Directly compressed solid dosage articles  
Solid dosage articles such as pharmaceutical tablets for the controlled release of a desired compound such as an active ingredient are directly compressed from a flowable, compressible mixture of...
6620432 Phenytoin sodium pharmaceutical compositions  
A pharmaceutical composition is provided containing an admixture of phenytoin sodium and an erodible matrix which extends the release of the phenytoin sodium over about a two hour period. The...
6610323 Oral pharmaceutical pulsed release dosage form  
An enteric coated pharmaceutical dosage form comprising an H + ,K + -ATPase inhibitor is disclosed. The dosage form comprises at least two portions of the H + ,K + - ATPase inhibitor to be released...
6610328 Amoxicillin-clarithromycin antibiotic composition  
An antibiotic product for delivering at least Amoxicillin or Clarithromycin that is comprised of three dosage forms with different release profiles with each of Amoxicillin and Clarithromycin being...
6605300 Oral pulsed dose drug delivery system  
A multiple pulsed dose drug delivery system for pharmaceutically active amphetamine salts, comprising an immediate-release component and an enteric delayed-release component wherein (1) the enteric...
6605303 Oral pharmaceutical extended release dosage form  
An enteric coated pharmaceutical extended release dosage form of a H + , K + -ATPase inhibitor giving an extended plasma concentration profile of a H + , K + -ATPase inhibitor. The extended plasma...
6599529 Modified release multiple-units compositions of non-steroid anti-inflammatory drug substances (NSAIDs)  
An oral pharmaceutical modified release multiple-units composition for the administration of a therapeutically and/or prophylactically effective amount of a non-steroid anti-inflammatory drug...
6599931 Test system for characterizing the compatibility of bioactive substances and polyvinylpyrrolidone  
A test system for characterizing the compatibility of bioactive substances with polyvinylpyrrolidones in a solid dispersion consisting of one or more bioactive substances and...
6596311 Fast disintegrating tablets  
This invention provides a formulation for preparing a fast disintegrating tablet comprising a drug in multiparticulate form, one or more water insoluble inorganic excipients, one or more...
6592897 Slow release tablet prepared from linear water-insoluble polysacchrides  
The invention relates to a controlled release tablet which in part or as a whole contains water-insoluble linear polysaccharides, preferably the polysaccharide poly(1,4-α-D-glucan), in the form of...
6592902 Controlled release eplerenone compositions  
The invention relates to oral pharmaceutical compositions useful as aldosterone receptor blockers comprising the active agent micronized eplerenone in an amount of about 10 mg to about 1000 mg and...
6576260 Sustained-release form of administration containing tramadol saccharinate  
Disclosed herein is sustained-release formulations of tramadol comprising tramadol saccharinate coated with at least one sustained-release coating. The sustained release formulations may also...
6572889 Controlled release solid dosage carbamazepine formulations  
A polymer or copolymer composition derived from one or more unsaturated carboxylic acids that is cross-linked and carbamazepine in conjunction with conventional materials such as fillers,...
6569455 Quick-release extrudates, method for preparing the same and compositions obtained from said extrudates  
The present invention relates to stable quick-release extrudates that contain low-viscosity hydroxypropylcellulose and at least one active ingredient. This invention also relates to a method for...
6565883 Controlled release oral compositions comprising rivastigmine  
Pharmaceutical composition capable of releasing a therapeutically effective dose of active agent, e.g., rivastigamine, in a time-controlled manner.
6558703 Porous hydroxyapatite particles as carriers for drug substances  
A drug delivery system for oral administration in solid dry form of a greasy/oily/sticky substance and a pharmaceutically active substance or a pharmaceutically active substance which itself is...
6558699 High drug load immediate and modified release oral dosage formulations and processes for their manufacture  
This invention relates to high drug load granulation of (E)-α-[2-n-butyl-1-[(4-carboxyphenyl)methyl]-1H-imidazol-5- yl]methylene-2-thiophenepropionic acid in the anhydrous form, a process for its...
6558701 Multilayer tablet for administering a fixed combination of tramadol and diclofenac  
A multilayer tablet for oral administration containing at least one Tramadol layer including Tramadol or a physiologically acceptable salt thereof; at least one diclofenac layer including...
6558700 Multiple-unit sustained release tablets  
A multiple-unit sustained release tablet characterized by consisiting of a granular part and a powdery part, each granule comprising a matrix composed of a water-insoluble polymer and an active...
6555136 Pharmaceutical dosage form for pulsatile delivery of methylphenidate  
Novel pharmaceutical dosage forms provide for pulsatile delivery of methylphenidate, i.e., release encapsulated drug in spaced apart “pulses.” The dosage forms are comprised of first, second...
6555137 Sucralfate-containing composition and process for the preparation thereof  
A coated antacid comprising sucralfate and an antacid inhibits decline in the adhesion characteristics of sucralfate whereby the drug ingested can reliably show its effect in the stomach. This...
6551618 Compositions and methods for delivery of agents for neuronal regeneration and survival  
Devices useful in the delivery of DNA encoding neurotrophic agents, anti-fibrotic agents, and related compositions are disclosed herein for use in the treatment of central and/or peripheral nervous...
6548083 Prolonged release active agent dosage form adapted for gastric retention  
The present invention is directed to an active agent dosage form which is adapted for retention in the stomach and useful for the prolonged delivery of an active agent formulation to a fluid...
6544556 Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and a proton pump inhibitor  
An oral solid dosage form includes a therapeutically effective amount of an NSAID and a proton pump inhibitor in an amount effective to inhibit or prevent gastrointestinal side effects normally...
6544553 Dosage forms and methods for oral delivery of progesterone  
Provided is an oral dosage form suitable to deliver a combined dosage of progesterone and which upon delivery through the gastrointestinal tract provides a blood concentration of from about 0.1...
6534089 Uniform drug delivery therapy  
The invention disclosed pertains to a novel delivery system comprising an agent formulation and means for dispensing the agent formulation from the delivery system.
6534088 Fibrate-statin combinations with reduced fed-fasted effects  
This invention discloses an orally administered pharmaceutical composition for the treatment of elevated levels of cholesterol and related conditions comprising a statin and fenofibrate in the form...
6534090 Oral osmotic controlled drug delivery system for a sparingly soluble drug  
The present invention is for an oral osmotic controlled drug delivery system for a sparingly soluble drug comprising: a. a core comprising (i) finely particulate anhydrous carbamazepine (ii) a...
6531158 Drug delivery system for enhanced bioavailability of hydrophobic active ingredients  
The present invention provides a drug delivery system for the oral administration of a hydrophobic active ingredient. The active ingredient's post-ingestion dissolution rate and its corresponding...
6524618 Directly compressible extended-release matrix formulation for metformin hydrochloride  
An extended-release matrx formulation capable of being directly compressed into tablets comprising metformin hydrochloride blended with specific excipients. The excipients used in the formulation...
6517866 Sertraline salts and sustained-release dosage forms of sertraline  
Sustained release dosage forms of sertraline which release sertraline at a rate between 1 mgA/hr and 40 mgA/hr. The dosage forms may exhibit an initial delay period during which sertraline is...
6514531 Controlled-release dosage forms comprising zolpidem or a salt thereof  
The present invention relates to controlled-release dosage forms of zolpidem or salts thereof adapted to release zolpidem over a predetermined time period, according to a biphasic profile of...
6488962 Tablet shapes to enhance gastric retention of swellable controlled-release oral dosage forms  
The retention of oral drug dosage forms in the stomach is improved by using swellable dosage forms that are shaped in a manner that will prevent them from inadvertently passing through the pylorus...
6485743 Method and composition of an oral preparation of itraconazole  
The present invention relates to a method and composition of an oral preparation of itraconazole, an excellent azole antifungal drug. More particularly, it relates to an oral preparation of...
6485759 Botanical combinations for treating AIDS and immune-deficient patients to maintain good health and the process for preparing the same  
Botanical Combination therapies for treating AIDS and immune-deficient patients include therapeutically effective doses of five medicinal plants of Thailand. First combination, ayurvedic...
6482434 Method for reducing adverse effects of a weight loss regimen  
A method for reducing certain effects associated with a negative calorie balance in a human includes the step of administering conjugated linoleic acid to a human in an amount effective to reduce...
6475521 Biphasic controlled release delivery system for high solubility pharmaceuticals and method  
A biphasic controlled release delivery system for pharmaceuticals which have high water solubility, such as the antidiabetic metformin HCl salt, is provided which provides a dosage form that has...
6468976 Monohydrate lisinopril  
The present invention relates to a novel monohydrate form of 1-(N 2 -[(S)-1-carboxy-3-phenylpropyl]-L-lysyl)-L-proline known under the generic name lisinopril. Further, the present invention also...
6468959 Peroral dosage form for peptide containing medicaments, in particular insulin  
There is provided a plural dosage form for peptide pharmaceuticals comprising a matrix of gelatin or gelatin derivative having distributed therein the peptide pharmaceutical in particular insulin,...
6462022 Lisinopril compositions having large-particle DCPD  
The present invention relates to a pharmaceutical composition comprising lisinopril and dibasic calcium phosphate dihydrate (DCPD), produced by a process comprising mixing lisinopril and DCPD with...
6451345 Functional coating of linezolid microcapsules for taste-masking and associated formulation for oral administration  
The present invention provides taste-masked microcapsules of Linezolid or the like (any member of the orally effective oxazolidinone or macrolide antibiotics), suitable for oral administration as a...
6399096 Pharmaceutical formulation  
A solid, oral controlled release pharmaceutical dosage form has a water-soluble active ingredient dispersed in a matrix and releases the active ingredient at such a rate upon administration that...
6399100 Controlled release pharmaceutical compositions containing tiagabine  
Controlled release oral pharmaceutical preparations are provided which comprise a therapeutically effective amount of tiagabine or a pharmaceutically acceptable salt thereof dispersed in a rate...
6391338 System for rendering substantially non-dissoluble bio-affecting agents bio-available  
The present invention is a method of preparing a system for delivering a bio-affecting agent and the composition prepared thereby. The invention includes forming a molecular dispersion of the...
6372255 Tablet for instant and prolonged release of one or more active substances  
A multi-layer tablet for the instant and prolonged release of active substances comprises at least two layers where the first outer layer comprises a mixture of excipients and an active substance,...
6365185 Self-destructing, controlled release peroral drug delivery system  
The present invention relates to tablets which are time-controlled to release active agent at different rates in different regions of the digestive tract in order to maintain a substantially...
6365180 Oral liquid compositions  
The present invention relates to novel, liquid and semi-solid pharmaceutical compositions which can be administered in liquid form or can be used for preparing capsules containing such...