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6344215 |
Methylphenidate modified release formulations
A pharmaceutical MR (modified release) multiparticulate dosage form such as a capsule (once-a-day MR Capsule) of Methylphenidate indicated for the treatment of children with attention deficit...
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6342250 |
Drug delivery devices comprising biodegradable protein for the controlled release of pharmacologically active agents and method of making the drug delivery devices
The present invention relates to an improved method of making drug delivery devices for the controlled release of pharmacologically active agents and further, to drug delivery devices made by such...
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6340474 |
Composition for potentiating a growth hormone and a method for preparation of said composition
A pharmacologically acceptable growth hormone-potentiating composition for ingestion in a mammal, in a pill form. The composition includes a first herbal extract having an element to synthesize a...
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6338857 |
Sustained release carbamazepine pharmaceutical composition free of food effect and a method for alleviating food effect in drug release
The invention provides a sustained release composition free of food effect comprising: (c) a core comprising carbamazepine; and (d) a functional coating comprising, based on the weight of the...
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6333048 |
Solid medicament form with active agent distributed in flat polymer fragments
In a solid medicament form for the peroral application of active agents containing a uniform distribution of active agent in a polymer material, the polymer material is in the form of flat fragments.
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6328979 |
Sustained release medicinal compositions
The present invention relates to sustained-release pharmaceutical compositions for ionic pharmaceutically active substances (excluding ionic prostanoic acid derivatives) containing ionic compounds...
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6326027 |
Controlled release formulation
A controlled release preparation for oral administration contains tramadol, or a pharmaceutically acceptable salt thereof, as active ingredient.
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6326360 |
Bubbling enteric coated preparations
An object of the present invention is to obtain an oral glycyrrhizin preparation not only manufacturable by a simple method but also having an excellent property of being absorbed from the...
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6322815 |
Multipart drug delivery system
Polymeric drug conjugates in controlled release matrices are provided which allow sustained concentrations of therapeutic agents within a treated area for a prolonged period. The polymeric drug...
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6319512 |
Implants for controlled release of pharmaceutically active principles and method for making same
The present intention relates to an implant for the controlled release of at least one pharmaceutically active principle comprising a core containing at least one active principle and a sheath...
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6319518 |
Colon selective drug delivery composition
A composition comprising gelatin and a polysaccharide which is degradable by a colonic enzyme and, optionally, with an aldehyde and/or a polyvalent metal ion and/or an additional polysaccharide,...
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6319520 |
Solid thermoformable controlled-release pharmaceutical composition
The present invention relates to a new solid controlled-release pharmaceutical composition obtained by thermoforming, in the hot state, a mixture based on polymers belonging to the polymethacrylate...
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6316008 |
Combination of zinc ions and vitamin C and method of making
Compositions for oral use containing at least one zinc compound, at least one amino acid, a source of ascorbic acid which does not appreciably associate with zinc ions, and a base material. The...
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6312728 |
Sustained release pharmaceutical preparation
The present invention pertains to a sustained release drug delivery system which comprises a core of active ingredient, an enteric coating, a second coating of active ingredient and lastly a...
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6306437 |
Apomorphine-containing dosage forms for ameliorating male erectile dysfunction
Psychogenic impotence can be ameliorated without substantial undesirable side effects by administration of apomorphine and an antiemetic agent in an amount sufficient to substantially reduce nausea...
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6306436 |
Stabilized, acid-free formulation for sustained release of bupropion hydrochloride
Stabilized bupropion hydrochloride pharmaceutical compositions are disclosed that are free of acid additives and provide for a sustained release of the bupropion hydrochloride. The particulate...
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6306900 |
Enteric coated pharmaceutical compositions
This invention provides a pharmaceutical composition comprising a mycophenolate salt, the composition being adapted to release mycophenolate in the upper part of the intestinal tract.
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6303143 |
Pharmaceutical product
A substrate is roboticaly picked up at a station and transported to a measuring station to measure the distance to a reference. The substrate is aligned to a robot before measurement. The measured...
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6303144 |
Preparations with controlled release
A controlled release preparation containing at least one kind of a pharmaceutically active ingredient, a male piece and a female piece, the pieces fitting together to enclose the active substance...
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6296873 |
Zero-order sustained release delivery system for carbamazephine derivatives
A zero-order sustained-release delivery system for delivery of carbamazepine or a derivative thereof. A polymeric matrix formulation of carbamazepine comprises hydrophilic polymer or...
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6296874 |
Core formulation comprising troglitazone and abiguanide
This invention relates to a combination drug product comprising troglitazone, e.g. its hydrochloride, and a biguamide, e.g. metformin. In particular, the product comprises a core of metformin, at...
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6294199 |
Method of treating a bacterial infection comprising administering amoxycillin
Bacterial infections may be treated using a high dosage regimen of amoxycillin. Preferably, the dosage is provided by a bilayer tablet.
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6291428 |
Peptides which promote bone-forming cell attraction and adhesion
Peptides are provided with the properties of enhancing the migration and adhesion of bone-forming cells to a substrate, useful for promoting bone mineralization and osseointegration in the healing...
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6290990 |
Slow-release matrix pellets and the production thereof
Slow-release matrix pellets with a spherical or lenticular shape and uniform maximum diameters in the range from 0.5 to 4 mm, composed of a) 0.1-87% by weight of at least one biologically active...
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6287598 |
Method for providing sustained antiepileptic therapy
This invention pertains to a dosage form for the management of epilepsies wherein the dosage form comprises administering valproic acid or a valproic acid derivative at a continuous rate over an...
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6287600 |
Stabilized pharmaceutical composition of a nonsteroidal anti-inflammatory agent and a prostaglandin
A pharmaceutical composition is provided for the oral administration of an NSAlD and a prostaglandin. The composition is a solid dosage form wherein the NSAID is enterically coated and the...
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6287595 |
Biomedical assay device
The present invention provides an integrated structural unit that includes a diagnostic form that includes at least one active ingredient that is present in an amount that advantageously does not...
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6284274 |
Analgesic tablet compositions
An opiate analgesic composition and a non-opiate analgesic composition are disclosed for delivering an analgesic in either embodiment to a patient in need of relief from pain. The analgesics are...
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6284275 |
Controlled release tablet having a unitary core
A controlled release pharmaceutical tablet containing antihyperglycemic drug and a hypoglycemic drug that does not contain an expanding or gelling polymer layer and comprising a core containing the...
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6284262 |
Compact dosage unit for buccal administration of a pharmacologically active agent
A simple and compact buccal dosage unit is provided for administering a pharmacologically active agent to a mammalian individual. The buccal dosage unit comprises the active agent to be...
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6277366 |
Release-sustaining agent for drugs and sustained-release pharmaceutical composition
A sustainedly releasing agent for medicines comprising a non-crosslinked type anion-exchange resin represented by the general formula (I): ##STR1## wherein R 1 represents aralkyl or alkyl, each of...
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6274173 |
Oral pharmaceutical composition with delayed release of active ingredient for pantoprazole
An oral pharmaceutical composition comprises an acid-labile irreversible proton pump inhibitor in pellet or tablet form, wherein the irreversible proton pump inhibitor is at least partly in...
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6270803 |
Controlled-release garlic formulations
There are provided orally-administrable formulations for the controlled release of granulated garlic, comprising particles of granulated garlic coated with a film comprising a mixture of at least...
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6270797 |
Sustained release pharmaceutical composition containing glipizide and method for producing same
One aspect of the invention resides in a monolithic sustained release composition of glipizide for patients with non-insulin dependent diabetes mellitus that exhibits a breakdown after ingestion by...
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6267969 |
Unit-of-use reagent composition for specific binding assays
Unit-of-use reagent compositions and methods for preparing such reagent compositions are disclosed. The reagent composition comprises one or more reagents which are necessary for a specific binding...
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6267986 |
Process for the preparation of a controlled drug delivery system containing pseudoephedrine and a long acting antihistamine
This invention relates to a process for the preparation of a controlled release pharmaceutical composition comprising two discrete zones wherein the first discrete zone comprises therapeutically...
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6264985 |
Laminated tablet with pointed core
A dry-coated tablet for controlled release of active substance, having an erodible core tablet (1) containing at least one active substance, and a substantially erosion-resistant shell consisting...
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6264974 |
Buccal and sublingual administration of physostigmine
Physostigmine, 1,2,3,3a,8,8a-hexahydro-1,3a,8-trimethylpyrrolo[2,3-b] indol-5ol methylcarbamate, administered buccally or sublingually in non-sustained release dosage form provides extremely...
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6261601 |
Orally administered controlled drug delivery system providing temporal and spatial control
A pharmaceutical composition in the form of tablets or capsules provides a combination of temporal and spatial control of drug delivery to a patient for effective therapeutic results. The...
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6254887 |
Controlled release tramadol
A controlled release preparation for oral administration contains tramadol, or a pharmaceutically acceptable salt thereof, as active ingredient.
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6254882 |
Methods and compositions for treating pulmonary disorders using optically pure (S)--salmeterol
A method and composition are disclosed utilizing the pure (S) isomer of salmeterol which is a potent bronchodilator with reduced adverse effects, having a better selectivity for β 2 receptors...
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6254889 |
Solid dispersion dosage form of amorphous xanthine derivative and enteric-coating polymer
The present invention relates to a solid dispersion and a solid dispersion dosage form which comprise a xanthine derivative represented by the following formula (I) or a pharmacologically allowable...
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6251430 |
Water insoluble polymer based sustained release formulation
Sustained release drug formulations contain the pharmaceutical itself and a three component release rate controlling matrix composition. The three components of the matrix composition are (1) water...
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6251434 |
Preparations of non-steroidal analgesics
Preparations of non-steroidal analgesics with antipyretic and antiinflammatory effect are obtainable by extrusion and shaping of a melt, comprising, besides one or more active ingredients, a...
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6248355 |
Pharmaceutical composition containing an acid-labile omeprazole and process for its preparation
A composition, particularly adapted for oral administration, containing omeprazole, and a method for preparing the composition, are disclosed. The composition, being exempt of alkaline-reacting...
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6248760 |
Tablet giving rapid release of nicotine for transmucosal administration
A tablet for the transmucosal administration of nicotine. The nicotine is in one or more layers upon a non-nicotine containing matrix. The nicotine layers rapidly dissolve in the mouth. The...
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6248359 |
Multi-tablet oxybutynin system for treating incontinence
The present invention provides a simple multi-tablet system for the treatment of urinary incontinence with oxybutynin. Particular embodiments of the invention provide a first tablet that releases...
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6245357 |
Extended release dosage form
A dosage form comprising a composition comprising a drug surrounded by an interior and an exterior wall with an exit for administering the drug to a patient; and a method of using the dosage form...
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6245360 |
Nutritional supplement
A single entity product is provided for administration to persons being treated for nutritional deficiencies associated with addiction to alcohol, wherein the product is an extended-release...
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6245354 |
Drug delivery system using galactoxyloglucan
The present invention relates to a pharmaceutical sustained release preparation prepared by using as a sustained release ingredient a partial degradation product of the galactose of a...
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