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7402321 Oral administration form for pyridin-2-ylmethylsulfinyl-1H-benzimidazoles  
The invention relates to an oral administration form for pyridin-2-ylmethylsulfinyl-1H-benzimidazoles and their salts, which comprises the active compound together with tablet disintegrants and is...
7399486 Method of preparing mixed formulation of sustained release microspheres by continuous one-step process  
Disclosed is a method for preparing a mixed formulation of sustained release microspheres with various compositions by a continuous one-step process. The present method is characterized by...
7387792 Pharmaceutical composition for compressed annular tablet with molded triturate tablet for both intraoral and oral administration  
New pharmaceutical compositions in unit dosage form are disclosed for both intraoral and oral administration to a patient, said unit dosage form configured to be placed intraorally of said...
7384653 Oral dosage form comprising a therapeutic agent and an adverse-effect agent  
The present invention provides an oral dosage form comprising a first composition and a second composition. The first composition comprises an effective amount of a therapeutic agent and the...
7378394 Sustained-release microparticle preparation of human growth hormone and process for producing thereof  
Provided is a sustained-release microparticle preparation of a human growth hormone which combines biodegradability with sustained-release performance while avoiding the use of an organic solvent...
7342048 Bioabsorbable pharmaceutical formulation  
A bioabsorbable release-sustaining pharmaceutical formulation using a biodegradable release-sustaining base material which can prevent an effective component drug from being released too rapidly...
7338667 Pharmaceutical formulation  
The present invention concerns an extended release formulation having an accelerating erosion and/or dissolution rate of the surface of the formulation. The formulation comprises a drug having low...
7338942 Composition and method for maintaining healthy mobile joints and cartilage  
Compositions and methods for maintaining healthy mobile joints and cartilage in humans and animals are disclosed. The composition comprises glucosamine and chondroitin dispersed in a...
7335380 Amlodipine free base  
Amlodipine free base can be formulated into a convenient oral dosage form, especially a tablet, without excessive stickiness or tablet punch residue. The amlodipine free base can be crystalline...
7329418 Pharmaceutical tablets having height greater than width  
An immediate release compressed pharmaceutical tablet that has two or more segments and a top and a bottom and has a height that exceeds the width of the tablet. The height is measured vertically...
7318935 Pharmaceutical tablets with active and inactive segments  
An immediate release compressed pharmaceutical tablet that has two or more segments and a top and a bottom and has a height that exceeds the width of the tablet. The height is measured vertically...
7316818 Liposome drug delivery of polycyclic, aromatic, antioxidant or anti-inflammatory compounds  
This invention comprises pharmaceutical compositions for administering a polycyclic, aromatic, antioxidant or anti-inflammatory compound to an animal. Particularly provided are proliposomal...
7314638 Preparing method for controlled released type tablet tamsulosin HCL and the tablet thereof  
The present invention relates to a simple and effective method for preparing a tamsulosin HCl sustained-release tablet and a tamsulosin HCl sustained-release tablet produced thereby. The method...
7314640 Formulation and process for drug loaded cores  
The present invention relates to a controlled release pellet of metoprolol and its pharmaceutically acceptable salts that uses a water soluble or a water swellable inert starting seed or core.
7304043 β-L-2′-deoxy-nucleosides for the treatment of hepatitis B  
This invention is directed to a method for treating a host infected with hepatitis B comprising administering an effective amount of an anti-HBV biologically active...
7300668 System for manufacturing controlled release dosage forms, such as a zero-order release profile dosage form manufactured by three-dimensional printing  
The present invention includes controlled release dosage forms and methods of designing and manufacturing dosage forms to obtain specific release profiles, for example, zero-order release...
7282216 Biocompatible polymer blends and uses thereof  
The present invention relates to a novel series of polymers which have been prepared by blending hydrophobic biocompatible, biodegradable polymers or copolymers, such as...
7276252 Method and form of a drug delivery device, such as encapsulating a toxic core within a non-toxic region in an oral dosage form  
A drug delivery device such as an oral dosage form (ODF) with a toxic or potent core encapsulated by a non-toxic region. The non-toxic region may be a region including multiple layers, coatings,...
7276250 Sustained release formulations of oxymorphone  
Sustained release formulations of oxymorphone or pharmaceutically acceptable salts thereof; methods for making the sustained release formulations of oxymorphone or pharmaceutically acceptable...
7276251 Sustained-release composition of drugs encapsulated in microparticles of hyaluronic acid  
A sustained-release drug composition consisting essentially of microparticles of hyaluronic acid having a high molecular weight or an inorganic salt thereof and a protein or peptide drug encased...
7271156 Immunostimulatory nucleic acids  
The invention relates to immunostimulatory nucleic acid compositions and methods of using the compositions. The T-rich nucleic acids contain poly T sequences and/or have greater than 25% T...
7270831 Orally administrable opioid formulations having extended duration of effect  
Sustained release oral solid dosage forms of opioid analgesics are provided as multiparticulate systems which are bioavailable and which provide effective blood levels of the opioid analgesic for...
7258872 Chromone enteric release formulation  
Orally administered chromones have been found to be effective in the treatment of allergic conditions such as asthma, general food allergies, ulcerative colitis, atopic eczema, chronic urticaria,...
7255876 Composition comprises sustained-release fine particles and manufacturing method thereof  
The present invention relates to a composition comprising sustained-release fine particles, characterized in that it contains sustained-release fine particles that can be used in...
7250176 Method of treating a bacterial infection  
Bacterial infections may be treated using a high dosage regimen of amoxicillin and potassium clavulanate. Preferably, the dosage is provided by a bilayer tablet.
7247491 Method for determining release of a peptide from a sustained release polylactide formulation  
A method for determining the release of a peptide from a sustained release polylactide formulation which can be carried out in a shorter time than a real-time method by accelerating the release of...
7241457 Osmotically driven active agent delivery device providing an ascending release profile  
In one aspect, the present invention is directed to an osmotic pump that automatically provides an ascending release rate of active agent as the osmotic pump functions in an environment of...
7235258 Sustained-release formulations for treating CNS-mediated disorders  
Sustained-release compositions for delivering therapeutic concentrations of isovaleramide, isovaleric acid, and certain structurally related compounds are provided for the treatment for a variety...
7229640 Paroxetine controlled release compositions  
A controlled release or delayed release formulation contains a selective serotonin reuptake inhibitor (SSRI) such as paroxtine.
7229642 Amino acid modulated extended release dosage form  
Disclosed herein is a oral extended release dosage form comprising a plurality of granules of an effective amount of a pharmaceutically active compound, at least one amino acid, and an...
7226614 Tablet comprising cetirizine and pseudoephedrine  
The present invention concerns a tablet comprising two distinct segments. More particularly, the invention relates to combinations of two pharmaceutical substances and methods of treatment of...
7220430 Sustained-release preparation and process for producing the same  
The present invention is to provide a sustained release preparation comprising a drug-containing core substance and a multilayered coating layer covering the core substance, wherein all adjacent...
7217430 Compositions and methods of treatment comprising amoxicillin and potassium clavulanate with xanthan  
Bacterial infections may be treated using a high dosage regimen of amoxicillin and potassium clavulanate. Preferably, the dosage is provided by a bilayer tablet.
7214387 Sustained release formulations of metformin  
The invention provides sustained release formulations of metformin or a pharmaceutically acceptable salt thereof, and methods of treating diabetes by administering to a patient a therapeutically...
7214385 Pharmaceutical formulation containing dye  
Methods and compositions for preventing abuse of dosage forms comprising an opioid analgesic and an aversive agent (e.g., a dye) in an effective amount to deter an abuser from administering a...
7208176 Drug delivery device containing neuraminidase inhibitor and an H1 antagonist  
The present invention provides a dual release solid dosage form containing a first composition that releases a neuraminidase inhibitor, such as oseltamivir, zanamivir, or peramivir, in a...
7198803 Sustained release oral preparations  
Medicinal preparations containing a drug 2-amino-3-cyano-5-2(2-fluorophenyl) -4-methylpyrrole wherein the QOL and compliance of patients taking this drug can be improved and an unnecessary...
7195769 Pharmaceutical compositions of anti-tubercular drugs and process for their preparation  
A pharmaceutical composition of anti-tubercular drugs for oral use comprising Rifampicin and/or Isoniazid wherein the bioavailability of Rifampicin and/or other drugs is enhanced. Preferably the...
7192612 Compositions and methods based on synergies between capsicum extracts and tea catechins for prevention and treatment of cancer  
The invention described herein encompasses methods and compositions of preventing or treating cancer comprising the administration of a combination of therapeutically effective amount of...
7192608 Method of manufacturing drug granules, the drug granules and pharmaceutical preparation containing the drug granules  
The present invention provides coated granules using drug granules containing a water soluble drug as an active ingredient at a high density, which is superior in uniform content and stability,...
7189414 Controlled release oral drug delivery system  
The invention relates to synchronous drug delivery composition comprising a polymeric matrix which comprises hydrogel blended with a hydrophobic polymer, so as to form an erodible matrix, a drug,...
7179486 Process for preparing sustained release tablets  
The present invention is directed to the process of preparing a sustained release niacin tablet and the product prepared therefrom.
7172767 Opioid agonist / antagonist combinations  
The invention is directed in part to oral dosage forms comprising a combination of an orally analgesically effective amount of an opioid agonist and an orally active opioid antagonist, the opioid...
7166301 Immediate release medicinal compositions for oral use  
The present invention relates to an immediate release oral pharmaceutical composition which comprises as an active ingredient calcium salt of a benzylsuccinic acid derivative represented by the...
7163926 Adjuvant-containing vaccines  
This invention provides a DNA vaccine which comprises a naked DNA incorporating and expressing in vivo a nucleotide sequence encoding an antigenic polypeptide, preferably a gene of a pathogenic...
7163694 Bioerodible poly(ortho esters) from dioxane-based di(ketene acetals), and block copolymers containing them  
Bioerodible poly(ortho esters) useful as orthopedic implants or vehicles for the sustained delivery of pharmaceutical, cosmetic and agricultural agents from dioxane-based di(ketene acetals). Block...
7157100 Pharmaceutical composition for controlled drug delivery system  
The present invention describes a novel controlled release multilayer composition that is capable of delivering a first active agent from one layer immediately followed by continuous controlled...
7153523 Biologically absorbable polyhydroxycarboxylic acid and production method thereof  
A biologically absorbable polyhydroxycarboxylic acid in which a content of water-soluble acid components is not more than 0.07 mol/kg in terms of monobasic acids, and which has a weight average...
7151173 Admixture, extrudable hydraulic composition and method for the selection of admixture  
A nonionic water-soluble cellulose ether is characterized in that when 3 pbw of the nonionic water-soluble cellulose ether is added to a mixture of 90 pbw of cordierite, 10 pbw of ordinary...
7147870 Osmotic device containing pseudoephedrine and an H1 antagonist  
The present invention provides an osmotic device containing controlled release pseudoephedrine in the core in combination with a rapid release H1 antagonist in an external coat. A wide range of H1...