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7759368 Sustained release composition for oral administration of niacin  
A sustained release composition for oral administration of niacin, comprising niacin; a carrier for sustained release composed of a hydrophilic polymer and a hydrophobic polymer; and a...
7754715 Sustained-release oral molsidomine composition for treating atherosclerosis  
The present invention, which is applicable in the pharmaceutical industry, relates to the use of molsidomine or one of its pharmaceutically acceptable salts, especially in the form of a...
7749537 Method of forming a tablet  
A method of forming a tablet includes the steps of pre-blending an active pharmaceutical ingredient susceptible to tackiness and a blending additive with a first mixing effort to form a pre-blend...
7736667 Shell-and-core dosage form approaching zero-order drug release  
Drugs are formulated as oral dosage forms for controlled release in which the release rate limiting portion is a shell surrounding the drug-containing core. The shell releases drug from the core...
7727553 Oral preparations with favorable disintegration characteristics  
The present invention provides oral preparations with good disintegration containing a slightly water-soluble active ingredient, which comprise a mixture of a solid formed product (e.g. a granule)...
7722898 Modified-release preparations containing oxcarbazepine and derivatives thereof  
Controlled-release preparations of oxcarbazepine and derivatives thereof for once-a-day administration are disclosed. The inventive compositions comprise solubility-and/or release enhancing agents...
7709025 Enteric coatings for orally ingestible substrates  
Enteric film coating systems for orally ingestible substrates such as pharmaceutical tablets and dietary supplements are disclosed. In preferred aspects, the enteric film coatings include an...
7709024 Sustained-release formulation and uses thereof  
The present invention provides sustained-release formulations useful and methods for using the same.
7704528 Binder composition and method for processing poorly compressible drugs into tablets of predetermined hardness and friability  
Tablets of a poorly compressible drug are made by direct compression using a binder composition which is a polymer, preferably a copolymer of polyvinylpyrrolidone (PVP) and vinyl acetate (VA),...
7704526 Sustained release composition for oral administration of drugs  
A sustained-release composition for oral administration of a drug, comprising the drug, a mixture of sodium alginate and xanthan gum as a carrier for sustained release and a mixture of...
7695734 Extended release tablet formulation containing pramipexole or a pharmaceutically acceptable salt thereof  
An extended release tablet formulation comprising pramipexole or a pharmaceutically acceptable salt thereof in a matrix comprising at least one water swelling polymer other than pregelatinized starch.
7682634 Pharmaceutical compositions  
Provided herein is a pharmaceutical composition comprising an antagonist, an agonist, a seal coat, and a sequestering polymer, wherein the antagonist, agonist, seal coat and at least one...
7682629 Floating pharmaceutical composition comprising an active phase and a non-active phase  
The invention concerns a floating pharmaceutical composition consisting of at least a first phase comprising at least a high dose active principle combined with one or several carriers and at...
7682633 Pharmaceutical composition  
Provided herein is a pharmaceutical composition comprising an antagonist, an agonist, a seal coat, and a sequestering polymer, wherein the antagonist, agonist, seal coat and at least one...
7682632 Tamper-resistant oral opioid agonist formulations  
Disclosed is an oral dosage form comprising (i) an opioid agonist in releasable form and (ii) a sequestered opioid antagonist which is substantially not released when the dosage form is...
RE41148 Oral pulsed dose drug delivery system  
A multiple pulsed dose drug delivery system for pharmaceutically active amphetamine salts, comprising an immediate-release component and an enteric delayed-release component wherein (1) the...
7662408 Sustained-release preparations  
A sustained release preparation comprising a combination of a microcapsule which gradually releases a GnRH agonist or a salt thereof for a long term, and a microcapsule which gradually releases a...
7655259 Delayed release carnitine  
A sustained release, orally administered pharmaceutical composition comprising carnitine and an acceptable pharmaceutical excipient is described for the treatment of carnitine deficiency and other...
7645459 Dosage forms of bisphosphonates  
Oral dosage forms of a bisphosphonate comprised of a safe and effective amount of a pharmaceutical composition comprising a bisphosphonate, a chelating agent, and, means for effecting delayed...
7632521 Controlled release potassium chloride tablets  
A unit dosage form, such as a tablet for delivering potassium into the body in a controlled release fashion, comprises of a multiplicity of microencapsulated potassium chloride crystals, which are...
7632520 Synergistic antibacterial formulation and to a method of making the same  
A synergistic antibacterial formulation and a method of making the same is disclosed. The composition contains Cefixime Trihydrate+Cloxacillin Sodium+Lactobacillus sporogenes spores. The...
7622137 Dosage forms contained within a capsule or sachet  
Provided are pharmaceutical dosage forms within structures such as hollow capsules, gelcaps, or sachets, adapted to allow ingestion of a whole dose or a preferably predetermined fraction of said...
7619007 Method and composition for administering an NMDA receptor antagonist to a subject  
The invention provides methods and compositions for administering an NMDA receptor antagonist (e.g., memantine) to a subject.
7618649 Extended release oral dosage composition  
A bilayer solid composition comprising (a) an immediate release first layer comprising an anti-allergic effective amount of desloratadine and at least one pharmaceutically acceptable excipient and...
7618650 Combination of a hypnotic agent and substituted bis aryl and heteroaryl compound and therapeutic application thereof  
The invention concerns the combination of a short-acting hypnotic agent and a compound of formula (I): Wherein X, Y, Z, A, B, D, Ar, R1 and R2 are as defined herein. The combination of this...
7611729 Dosage forms having prolonged active ingredient release  
The present invention relates to prolonged-release oral dosage forms of 4-phenylbutyric acid salts, such as sodium 4-phenylbutyrate. The prolonged release oral dosage forms are preferably tablets....
7611730 Tramadol-based medicament  
The invention relates to a medicament containing the racemate of tramadol in a retarded form and the (+)-enantiomer of tramadol in a non-retarded form.
7605138 Nucleic acid compositions for stimulating immune responses  
The invention provides an immunostimulatory nucleic acid comprising CpG motifs, and methods of use thereof in stimulating immunity.
7604820 Solid preparation containing chitosan powder and process for producing the same  
A colonic delivery solid preparation containing chitosan powder, which can control the dissolution of a medicament therefrom in the large intestine and release the medicament contained therein...
7585527 Composition and method for treating iron deficiency anemia  
A composition comprising heme iron and/or heme iron polypeptide in combination with ionic iron(s) and/or chelated iron(s). Administration of effective dosages of the present composition provides a...
7579020 Controlled release arginine α-ketoglutarate  
An oral formulation of arginine α-ketoglutarate is disclosed which formulation is comprised of arginine α-ketoglutarate and one or more excipient materials. A wide range of different controlled...
7576067 Pulsatile release compositions and methods for enhanced intestinal oligonucleotide drug absorption  
Delayed release oral pharmaceutical formulations and methods for enhanced intestinal drug absorption. The formulation comprises a first population of carrier particles comprising a drug and a...
7572463 Oral dosage forms  
A controlled-release oral dosage formulation of a salt-forming active ingredient, wherein the active ingredient is present as at least two different salts in a solid aggregation state, wherein the...
7553499 Sustained release tablet containing indapamide  
The present invention relates to a sustained release tablet containing indapamide and the process of manufacturing sustained release tablet containing indapamide. The tablet contains indapamide in...
7553500 Pharmaceutical composition having uniform drug distribution and potency  
Pharmaceutical compositions having uniform drug distribution and potency utilizing laxofoxifene as an active ingredient and containing a silicon dioxide to reduce loss of the active ingredient...
7550158 Controlled release by extrusion of solid amorphous dispersions of drugs  
Controlled release dosage forms for low solubility drugs are disclosed wherein an amorphous solid dispersion of the drug is coated with a non-dissolving and non-eroding coating that controls the...
7537784 Modified release tablet of bupropion hydrochloride  
A modified-release tablet of bupropion hydrochloride comprising (i) a core comprising an effective amount of bupropion hydrochloride, a binder, a lubricant; and (ii) a control releasing coat...
7524515 Pharmaceutical safety dosage forms  
Pharmaceutical safety dosage forms are provided which include a pharmaceutical and an antagonist to the pharmaceutical. The safety dosage forms are such that the antagonist has no significant...
7514100 Controlled release hydrocodone formulations  
A solid oral controlled-release dosage form of hydrocodone is disclosed, the dosage form comprising an analgesically effective amount of hydrocodone or a pharmaceutically acceptable salt thereof,...
7510727 Melt-extrusion multiparticulates  
A unit dose sustained-release oral dosage form containing a plurality of melt-extruded particles, each consisting essentially of a therapeutically active agent, one or more retardants, and an...
7488498 Antidiabetic preparation for oral administration  
There is provided a single preparation which directly decreases both of the post prandial blood glucose level and the fasting blood glucose level close to normal levels, by release-sustaining a...
7476403 Oral extended-release composition  
The invention is directed to controlled release formulations containing drugs which are preferably considered sparingly soluble to insoluble and which are suitable for administration to a patient...
7470435 Extended release venlafaxine formulation  
A controlled release dosage form of venlafaxine that comprises an immediate release pellet and an extended release pellet.
7465462 Multiparticulate controlled release selective serotonin reuptake inhibitor formulations  
A multiparticulate controlled release selective serotonin reuptate inhibitor (SSRI) formulation for oral administration is provided. The formulation includes particles of an SSRI or a...
7442387 Pharmaceutical composition for controlled release of active substances and manufacturing method thereof  
The present invention pertains to a sized product, which contains a drug, polyethylene oxide with a molecular weight of 2,000,000 or higher, and a specific size controlling agent for polyethylene...
7431943 Controlled release and taste masking oral pharmaceutical compositions  
Controlled release and taste masking compositions containing one or more active principles inglobated in a three-component matrix structure, i.e. a structure formed by successive amphiphilic,...
7431944 Delivery of multiple doses of medications  
Dosage forms for oral administration of a methylphenidate drug are provided. The dosage forms provide a substantially immediate dose of methylphenidate upon ingestion, followed by one or more...
7419684 System and method for manufacturing oral osmotic drug delivery devices, and methods of administering same  
A system and method for manufacturing oral osmotic drug delivery devices including the use of a mathematical model in deriving relationships between parameters used in manufacturing the devices...
7413749 Titration dosing regimen for controlled release tramadol  
A titration dosing regimen for the administration of controlled release tramadol analgesic to patients. The titration dosing regimen provides a significant reduction in the occurrence of adverse...
7413751 Methods of treatment using a gastric retained losartan dosage  
A method of treatment for hypertension and other disease states is described, which comprises the delivery of losartan in a gastric retained dosage form.