|
Match
|
Document |
Document Title |
|
|
6120803 |
Prolonged release active agent dosage form adapted for gastric retention
The present invention is directed to an active agent dosage form which is adapted for retention in the stomach and useful for the prolonged delivery of an active agent formulation to a fluid...
|
|
|
6117452 |
Fatty ester combinations
The thermoforming of compositions containing active agents is carried out by processing compositions containing certain fatty esters in combination.
|
|
|
6117450 |
Method of making a perorally administered solid drug with controlled effective ingredient delivery
The method of making a solid drug with controlled effective ingredient delivery for oral administration includes selecting a predetermined number of at least three of four compressed compositions...
|
|
|
6117451 |
Direct compression metformin hydrochloride tablets
Metformin Hydrochloride (herein referred to as metformin HCl) that may be 98.5%-100% pure is a high dose drug capable of being directly compressed with specific excipients into tablets having...
|
|
|
6110500 |
Coated tablet with long term parabolic and zero-order release kinetics
A tablet for the controlled release of an active pharmaceutical ingredient. The tablet comprises a core having a donut-like configuration with a cylindrical hole extending through the center of the...
|
|
|
6106863 |
Sustained-release metal valproate tablets
The present invention provides a sustained-release metal valproate tablet which is comparatively compact and is not influenced by a meal, the sustained-release metal valproate comprising a core...
|
|
|
6103263 |
Delayed pulse release hydrogel matrix tablet
The invention provides a delayed-pulse controlled release pharmaceutical tablet having: (a) from 20 to 60 wt. % of a low molecular weight hydroxypropyl cellulose having a number average...
|
|
|
6103264 |
Process for preparing a controlled release composition
A process for preparing a controlled release composition with a controlled release matrix and containing a pharmaceutically active ingredient, which comprises granulating the active ingredient with...
|
|
|
6103262 |
Modified-release metronidazole compositions and methods for making and using same
Pharmaceutical compositions having a modified release profile for once daily dosing of metronidazole, methods for making the pharmaceutical compositions, and methods for treating a microbial...
|
|
|
6099862 |
Oral dosage form for the controlled release of a biguanide and sulfonylurea
A controlled release pharmaceutical tablet containing antihyperglycemic drug and a hypoglycemic drug that does not contain an expanding or gelling polymer layer and comprising a core containing the...
|
|
|
6096339 |
Dosage form, process of making and using same
The invention disclosed pertains to a dosage form comprising an agent formulation comprising drug and pharmaceutical carrier of cooperating particle size and means for dispensing the agent...
|
|
|
6096341 |
Delayed release tablet of bupropion hydrochloride
The invention provides a controlled release tablet, free of stabilizer and free of pore-forming agent comprising: (i) a core consisting essentially of bupropion hydrochloride, a binder and a...
|
|
|
6090411 |
Monolithic tablet for controlled drug release
A swellable hydrophillic matrix tablet that delivers drugs in a controlled manner over a long period of time and is easy to manufacture. More specifically, the drug is disposed in a matrix composed...
|
|
|
6086920 |
Disintegratable microspheres
Microspheres which disintegrate quickly in water are composed of bio-affecting agent(s), disintegrant(s) and spheronization aid(s). The microspheres, which may have taste-masking coatings, are...
|
|
|
6086919 |
Pharmaceutical composition containing the ace inhibitor ramipril and a dihydropyridine compound
The invention is directed to a pharmaceutical composition which is a combination of the ACE inhibitor ramipril and a calcium antagonist of one of the dihydropyridine type compounds felodipine,...
|
|
|
6083533 |
Layered tablet for the controlled release of active substances
A layered tablet for the controlled release of active substances in a liquid medium comprising at least one active substance-containing, layered matrix with contact surfaces to the liquid medium...
|
|
|
6083514 |
Polymethylpentene container for an inhalation anesthetic
A pharmaceutical product. The pharmaceutical product includes a container constructed from a material containing polymethylpentene. The container defines an interior space. A volume of a...
|
|
|
6080428 |
Nicotinic acid compositions for treating hyperlipidemia and related methods therefor
An orally administered antihyperlipidemia composition according to the present invention includes from about 250 to about 3000 parts by weight of nicotinic acid, and from about 5 to about 50 parts...
|
|
|
6077537 |
Non-sedating acrivastine product
The present invention relates to methods of using and compositions containing acrivastine which provide antihistaminic therapeutic benefits while minimizing undesirable central nervous system side...
|
|
|
6077538 |
Controlled release tablet compositions
An opiate analgesic composition and a non-opiate analgesic composition are disclosed for delivering an analgesic in either embodiment to a patient in need of relief from pain. The analgesics are...
|
|
|
6068855 |
Pharmaceutical composition containing a fusible carrier and method for producing the same
A process for the manufacture of particles comprises mechanically working a mixture of a drug and a hydrophobic and/or hydrophilic fusible carrier in a high speed mixture so as to form...
|
|
|
6068854 |
Sol-controlled thermocolloid matrix based on gelatin for oral sustained-release form
A peroral depot medicament with controlled active substance release is composed of a gelatine matrix that continuously dissolves in an aqueous medium above 37° C., and a medicament distributed...
|
|
|
6068981 |
Marking of orally ingested products
A method of monitoring a therapeutic regimen in an animal, the method involving a) providing to the animal a therapeutic compound and a detectable compound that passes into the bloodstream,...
|
|
|
6066339 |
Oral morphine multiparticulate formulation
An oral morphine multiparticulate formulation for once-daily administration to a patient, comprising sustained release particles each having a core containing water soluble morphine and an osmotic...
|
|
|
6056968 |
Pharmaceutical drug dosage forms providing different release rates
A pharmaceutical dosage form comprises, in one portion thereof, a substantially single (+)-enantiomer of a chiral drug other than verapamil and, in another, separate portion thereof, a...
|
|
|
6056974 |
Rapid-release S1452 tablets
The present invention provides a rapid-release tablet of S1452 at least containing the following components: a. a principal agent comprising (+)-(Z)-calcium...
|
|
|
6039974 |
Pharmaceutical composition for combination of piperidinoalkanol-decongestant
The present invention provides a pharmaceutical composition in the form of a bilayer tablet comprising, (a) a first discrete zone made with Formulation (A) which comprises, a therapeutically...
|
|
|
6040434 |
Aldehyde oxidase inhibitors for treatment of aids
A new pathway of metabolism of 3'-azido-3'-deoxythymidine (AZT) to 3'-amino-3'-deoxythymidine (AMT) has been described. This pathway involves the enzyme aldehyde oxidase. Aldehyde oxidase...
|
|
|
6039980 |
Sustained release excipient
A sustained-release formulation for use in oral solid dosage forms includes from about 10 to about 40 percent or more by weight galactomannan gum; from about 1 to about 20 percent by weight of an...
|
|
|
6036976 |
Sustained release microspheres and preparation thereof
Disclosed is a method of producing microspheres which comprises subjecting a w/o/w emulsion or o/w emulsion to an in-water drying method under the following conditions: 1) the amount of...
|
|
|
6036973 |
Therapy for neurological diseases
A dosage form is disclosed for administering 10 ng to 1200 mg tacrine to a patient in need of tacrine therapy.
|
|
|
6033686 |
Controlled release tablet of bupropion hydrochloride
The invention provides a controlled release tablet, free of stabilizer and free of pore-forming agent comprising: (i) a core consisting essentially of bupropion hydrochloride, a binder and a...
|
|
|
6033685 |
Tablet for the controlled release of active agents
The present invention provides a tablet for the controlled release of an active agent comprising (a) a matrix layer comprising an active agent embedded in a non-swelling, non-gelling hydrophobic...
|
|
|
6027748 |
Pharmaceutical tablet, completely coated, for controlled release of active principles that present problems of bio-availability linked to gastro-intestinal absorption
Described herein is a particular type of pharmaceutical tablet, for oral use, which is formed by one or more layers, and is specifically designed for controlled release of active principles that...
|
|
|
6025391 |
Enteric-coated pharmaceutical compositions of mycophenolate
|
|
|
6022562 |
Medicinal and/or nutritional microcapsules for oral administration
The present invention relates to microcapsules for the oral administration of medicinal and/or nutritional active principles (AP), which are smaller than or equal to 1000 μm in size. These...
|
|
|
6022554 |
Polymeric microporous film coated subcutaneous implant
This invention relates to coating formulations for coating sustained-release drug implants. The coating formulations are capable of formulations are capable of forming a porous film coat over a...
|
|
|
6020002 |
Delivery of controlled-release system(s)
The present invention is a method and a dosage unit for delivery of a controlled-release system. The dosage unit is a quick dissolve unit which can be prepared by mixing uncured shearform matrix...
|
|
|
6013281 |
Method of making a pharmaceutical dosage form comprising a proton pump inhibitor
A new oral pharmaceutical dosage form comprising a core material that contains a proton pump inhibitor, one or more alkaline reacting compounds and optionally pharmaceutical excipients having a...
|
|
|
6010718 |
Extended release formulations of erythromycin derivatives
Disclosed is a pharmaceutical composition for extended release of an erythromycin derivative in the gastrointestinal environment. The composition comprises an erythromycin derivative and a...
|
|
|
6007841 |
Analgesic composition and method for treating pain
The analgesic effectiveness of a narcotic agonist-antagonist analgesic is significantly potentiated by administering a narcotic agonist-antagonist analgesic together with at least one nontoxic NMDA...
|
|
|
6001391 |
Process for producing solid drug forms having at least two phases
A process for producing solid combination tablets which have at least two phases comprises molding a melt of a polymeric binder with or without at least one active ingredient, there being at least...
|
|
|
5997903 |
Oral-administration forms of a medicament containing pantoprazol
The invention relates to oral presentation forms for pantoprazole, which consist of a core, an intermediate layer and an outer layer which is resistant to gastric juice.
|
|
|
5993855 |
Delayed drug-releasing microspheres
Microspheres prepared by emulsifying an aqueous phase containing a drug and an oil phase containing a biodegradable polymer to form a W/O emulsion, and then mixing and agitating this emulsion with...
|
|
|
5980942 |
Zero-order sustained release matrix tablet formulations of carbamazepine
A zero-order sustained-release delivery system for delivery of carbamazepine. A matrix tablet formulations of carbamazepine comprising hydrophilic polymer gel which inhibits transformation of...
|
|
|
5976571 |
Method for making a multi-stage drug delivery system
A drug delivery system (10) includes a first capsule half (12) having an inner chamber (16) for containing a drug (18) therein. A plug (28) is disposed in a passageway (26) of the capsule half (12)...
|
|
|
5968550 |
Liquisolid systems and methods of preparing same
Liquisolid systems are acceptably flowing and compressible powdered forms of liquid medications. According to the concept of liquisolid systems, liquid lipophilic drugs, or water-insoluble solid...
|
|
|
5965163 |
Substained release compositions and a method of preparing pharmaceutical compositions
A process for the manufacture of particles comprises mechanically working a mixture of a drug and a hydrophobic and/or hydrophilic fusible carrier in a high speed mixture so as to form...
|
|
|
5965161 |
Extruded multi-particulates
A unit dose sustained-release oral dosage form containing a plurality of melt-extruded particles, each consisting essentially of a therapeutically active agent, one or more retardants, and an...
|
|
|
5958452 |
Extruded orally administrable opioid formulations
Bioavailable sustained release oral opioid analgesic dosage forms, comprising a plurality of multiparticulates produced via melt extrusion techniques are disclosed.
|