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7144587 Pharmaceutical formulation containing opioid agonist, opioid antagonist and bittering agent  
Disclosed in certain embodiments is an oral dosage form comprising a therapeutically effective amount of an opioid analgesic; an opioid antagonist; and a bittering agent in an effective amount to...
7125567 Process for producing an oral sustained-release preparation of fasudil hydrochloride  
Disclosed is an oral sustained-release preparation which contains at least one active ingredient selected from the group consisting of fasudil hydrochloride and a hydrate thereof, the preparation...
7125563 Sustained release pharmaceutical preparations and methods for producing the same  
An extended release tablet comprising a core including albuterol sulfate and extended release agent; and an extended release coating on the core to provide for sustained release of the albuterol...
7122204 Antibiotic composition with inhibitor  
Antibiotic composition having four dosage forms with different release profiles providing for initial release of a beta lactam antibiotic followed by release of a beta-lactamase inhibitor,...
7122308 Detection of antidepressant induced mania  
Methods and kits for assessing the susceptibility of a patient to antidepressant-induced mania are described. The method involves testing a sample from a patient for the presence of the s variant...
7118762 Controlled release lipoic acid  
A controlled release formulation of lipoic acid is disclosed. The lipoic acid is combined with excipient materials in such a way that those materials provide for gradual release of the lipoic acid...
7108865 Controlled-release dosage forms of azithromycin  
A controlled-release dosage form of azithromycin having an improved side effect profile; a process for preparing the dosage form; and a method of treating a microbial infection, comprising...
7108866 Chronotherapeutic diltiazem formulations and the administration thereof  
A controlled-release Galenical preparation of pharmaceutically acceptable Diltiazem including the pharmaceutically acceptable salts thereof, suitable for evening dosing every 24 hours containing...
7108859 Antineoplastic product, use and formulation thereof  
An antineoplastic product is comprised of at least three dosages forms, each of which has a different release profile, with the Cmax for the antineoplastic product being reached in less than about...
7105174 Multiple-delayed release anti-neoplastic product, use and formulation thereof  
An anti-neoplastic product is comprised of at least three delayed release dosages forms, each of which has a different release profile, with the Cmax for the anti-neoplastic product being reached...
7094427 Combination immediate release controlled release levodopa/carbidopa dosage forms  
The present invention relates to dosage forms of a combination of carbidopa and levodopa comprising both immediate release and controlled release components for the treatment of ailments...
7090867 Controlled release delivery device for pharmaceutical agents incorporating microbial polysaccharide gum  
The present invention provides a controlled release device for sustained or pulsatile delivery of pharmaceutically active substances for a predetermined period of time. This invention further...
7090869 Method for producing preparation containing bioactive substance  
A method for producing a preparation containing a bioactive substance, characterized in that it comprises forming a solid material containing the bioactive substance and a polymer, and contacting...
7087249 Treatment of mucosal membranes  
The invention relates to the use of one or more antimicrobial metals preferably selected from silver, gold, platinum, and palladium but most preferably silver, formed with atomic disorder, and...
7083808 Controlled/modified release oral methylphenidate formulations  
The invention is directed to oral modified/controlled release methylphenidate formulations which provide a rapid initial onset of effect and a prolonged duration of effect. Preferably, the peak...
7083807 Pharmaceutical compositions for the controlled release of active substances  
The invention relates to pharmaceutical compositions which can be administrated orally, allowing the controlled release of at least one active substance comprising a) the said at least one active...
7074430 Controlled release tramadol tramadol formulation  
A controlled release preparation for oral administration contains tramadol, or a pharmaceutically acceptable salt thereof, as active ingredient.
7070803 Controlled release pharmaceutical composition for oral use containing midodrine and/or active metabolite, desglymidodrine  
Novel controlled release pharmaceutical compositions for oral use containing midodrine and/or its active metabolite desglymidodrine. The novel compositions are designed to release midodrine and/or...
7070806 Controlled release formulations coated with aqueous dispersions of acrylic polymers  
A stable solid controlled release formulation having a coating derived from an aqueous dispersion of a hydrophobic acrylic polymer includes a substrate including an active agent selected from the...
7063862 Pharmaceutical composition and method for treating  
Embodiments of the invention generally provide pharmaceutical drug compositions, methods of preparing oral drug compositions, such as extended release dosage compositions, and methods for treating...
7060299 Biodegradable microparticles that stabilize and control the release of proteins  
Disclosed herein are biodegradable microparticle compositions, and methods for the generation of biodegradable and biocompatible microparticles that stabilize proteins and also control the...
7056531 Sustained release compositions for orally administered substances and methods  
Sustained release composition for orally administered active substances that comprises maltodextrin and cellulose. This composition is suitable for forming tablets, gels when exposed to the fluids...
7048945 Timed pulsatile drug delivery systems  
A pharmaceutical dosage form such as a capsule capable of delivering therapeutic agents into the body in a time-controlled or position-controlled pulsatile release fashion, is composed of a...
7041317 Sustained-release preparation containing 5-acetyl-4,6-dimethyl-2[2-[4-(2-methoxyphenyl) piperazinyl]ethylamino] pyrimidine trihydrochloride as active ingredient  
A sustained-release formulation of 5-acetyl-4,6-dimethyl-2-[2-[4-(2-methoxyphenyl)piperazinyl]e thylamino]pyrimidine trihydrochloride coated with a release-controlling film comprising a...
7037523 Controlled release compositions for macrolide antimicrobial agents  
The present invention provides a controlled release pharmaceutical composition of an acid labile, poorly soluble drug having pH dependent solubility profile in aqueous environment. In a preferred...
RE39069 Multi-layered osmotic device  
The present invention provides a simple and improved multi-layered osmotic device (1) that is capable of delivering a first active agent in an outer lamina (2) to one environment of use and a...
7030162 Treatment of migraine headache  
The invention is directed to pharmaceutical compositions useful in the treatment of migraine. The compositions contain metoclopramide and one or more NSAIDs in unit dosage form. By selecting...
7029701 Composition for the treatment and prevention of ischemic events  
The invention relates to pharmaceutical compositions comprising omeprazole and aspirin wherein the combination is useful for the treatment and prevention of cardiovascular events including heart...
7025989 Multiple-delayed released antibiotic product, use and formulation thereof  
An antibiotic product is comprised of at least three delayed release dosages forms, each of which has a different release profile, with the Cmax for the antibiotic product being reached in less...
7022341 Pharmaceutical compositions containing epinastine and pseudoephedrine  
The present invention relates to novel oral pharmaceutical compositions comprising as pharmaceutically active compounds a combination of an antihistaminic-effective amount of epinastine or a...
7022342 Controlled release oral dosage form of beta-adrenergic blocking agents  
A sustained release beta-adrenergic receptor blocking agent, preferably propranolol, formulation.
7022345 Oral solid pharmaceutical formulations with pH-dependent multiphasic release  
Oral solid pharmaceutical compositions with pH-dependent multiphasic release, containing, as active ingredient, a molecule useful in the inflammatory bowel disease therapy, are described, being...
7018653 Method for preparing solid dosage form of desmopressin  
The present invention relates to a novel method for the preparation of a solid dosage form of desmopressin, or a pharmaceutically acceptable salt thereof, comprising providing a desmopressin...
7011850 Dosage forms having a barrier layer to laser ablation  
A dosage form for delivery of a therapeutic agent to a subject is described. The dosage form contains: (a) an outer wall defining an interior compartment; (b) within the interior compartment, a...
7011848 Hydrophobic component free sustained release nicotinic acid compositions for treating hyperlipidemia and related methods therefor  
An orally administered antihyperlipidemia composition according to the present invention includes from about 250 to about 3000 parts by weight of nicotinic acid, and from about 5 to about 50 parts...
7008641 Osmotic device containing venlafaxine and an anti-psychotic agent  
The present invention provides an osmotic device containing controlled release venlafaxine in the core in combination with an anti-psychotic agent in a rapid release external coat. A wide range of...
6994873 Multiparticulate formulations of lithium salts for oral administration suitable for once-a-day administration  
This invention refers to: multiparticulate formulations of Lithium salts for oral administration constituted by either modified release granules or mixtures of modified and conventional release...
6994871 Once a day antihistamine and decongestant formulation  
A controlled release pharmaceutical formulation for the administration of an antihistamine and decongestant to a patient wherein the formulation employs a compressed matrix core for the controlled...
6991807 Antibiotic composition  
Disclosed are antibiotic products for delivering at least two different antibiotics, wherein the products are comprised of at least three or four dosage forms with different release profiles and...
6989159 Pharmaceutical compositions containing lithium carbonate  
Once daily pharmaceutical compositions containing lithium carbonate in the form of coated granules.
6979468 Oral composition and method for the treatment of inflammatory cutaneous disorders  
A method and composition for the treatment of acne vulgaris, acne rosacea, and other inflammatory skin conditions comprises the oral administration of a composition comprising a dose of...
6976981 Osmotic delivery system with membrane plug retention mechanism  
An osmotic delivery system has a membrane plug retention mechanism which can also be used to control the delivery rate of a beneficial agent from the osmotic delivery system. The osmotic delivery...
6974591 Method for producing a controlled-release preparation  
The invention concerns a method for producing a controlled-release pharmaceutical preparation with a particle-containing coating, the coating being derived from an aqueous dispersion of a...
6974594 Method of preparing biological materials and preparations produced using same  
Methods for preparing products containing moisture-sensitive materials, including biological materials such as proteins, peptides or live cells, comprising at least the steps: (i) providing a...
6964780 Controlled-release pharmaceutical formulations  
The invention provides controlled-release formulations for oral administration containing a cGMP PDE-5 inhibitor. The formulations are useful, inter alia, in the treatment or prevention of sexual...
6962717 Pharmaceutical compositions  
A pharmaceutical composition for slow release of active ingredient in the gastrointestinal tract, comprising a plurality of active ingredient-containing particles coated with a material insoluble...
6960356 Orally administered drug delivery system providing temporal and spatial control  
A pharmaceutical composition in the form of tablets or capsules provides a combination of temporal and spatial control of drug delivery to a patient for effective therapeutic results. The...
6960357 Chemical delivery device  
The invention provides a controlled release dissolution and diffusion devices which can deliver an active ingredient at a constant or controlled-variable rate comprising an active ingredient and...
6958161 Modified release coated drug preparation  
A modified release preparation having one or more coated core elements, each core element including an active ingredient and having a modified release coating, wherein a stabilising coat is...
6955821 Sustained release formulations of guaifenesin and additional drug ingredients  
The invention relates to a novel pharmaceutical sustained release formulation of guaifenesin and at least one additional drug ingredient. The formulation may comprise a hydrophilic polymer,...