Sign up


Match Document Document Title
6821532 Methods and compositions for the treatment of benign prostatic hypertrophy  
This invention relates to a composition for use in treating benign prostatic hyperplasia including a saw palmetto extract provided in an oral controlled release formulation which allows release of...
6811794 Sustained release pharmaceutical dosage forms with minimized pH dependent dissolution profiles  
A pharmaceutical composition comprising at least one pharmaceutically active agent that is pH dependent, at least one non-pH dependent sustained release agent, and at least one pH dependent agent...
RE38629 Solid oral dosage form comprising a combination of metformin and glibenclamide  
The present invention relates to a solid oral dosage form comprising a combination of metformin and glibenclamide in which the size of glibenclamide is such that the glibenclamide bioavailability...
6806294 Opioid analgesic  
The invention is relative to a pharmaceutical preparation, especially for oral administration, with at least one active substance and with formulation components influencing the release of active...
6805880 Pharmaceutical delivery system for vitamin C and vitamin E and use of a combination of vitamin C and E for preventing or treating conditions involving oxidative stress  
A pharmaceutical delivery system comprising a slow-release formulation of vitamin C (ascorbic acid) and a plain-release formulation of vitamin E (tocopherol) has been found to raise and maintain...
6805881 Multiple unit controlled food effect-independent release pharmaceutical preparations and method for preparing the same  
The present invention relates to orally administrable multiple-unit sustained-release dose forms having controlled agitation-independent release of active compound and processes for their...
6797704 Systemic delivery of compounds through non-invasive bladder administration  
The present invention features methods of administering a therapeutic agent to a patient's lymph nodes by instillation of microparticles or nanoparticles comprising a biocompatible polymer and the...
6797283 Gastric retention dosage form having multiple layers  
The present invention is directed to a multilayered dosage form which is adapted for retention in the stomach and useful for the prolonged delivery of an active agent to a fluid environment of use....
6794464 Membrane or matrix for controlling the permeation rate of drugs  
A membrane or matrix for controlling the permeation rate of a drug, where the membrane or matrix includes a siloxane-based elastomer composition which contains at least one elastomer and optionally...
6790459 Methods for treating diabetes via administration of controlled release metformin  
A method for treating patients having non-insulin-dependent diabetes mellitus (NIDDM) by administering a controlled release oral solid dosage form containing preferably a biguanide drug such as...
6783773 Composition comprising amoxicillin and potassium clavulanate  
Bacterial infections may be treated using a high dosage regimen of amoxicillin and potassium clavulanate. Preferably, the dosage is provided by a bilayer tablet.
6783772 Pharmaceutical preparations containing alendronate sodium  
An oral composition in tablet form containing therapeutic amounts of alendronate sodium for release of the alendronate sodium in the stomach and by passing the oesophagus, comprising a compacted...
6780428 Unimolecular polymeric micelles with an ionizable inner core  
The present invention describes the preparation of unimolecular polymeric micelles (UPM) that bear a hydrophilic shell and a potentially ionizable and relatively hydrophobic core at a determined pH...
6780432 Core formulation  
This invention relates to a combination drug product comprising pioglitazone hydrochloride and a biguamide, e.g. metformin. In particular, the product comprises a core of the biguamide, e.g....
6773720 Mesalazine controlled release oral pharmaceutical compositions  
Controlled-release oral pharmaceutical compositions containing as active ingredient 5-amino-salicylic acid, comprising: a) an inner lipophilic matrix consisting of substances with a melting point...
6770295 Therapeutic formulation for administering tolterodine with controlled release  
The present invention is drawn to a method of treating an unstable or overactive urinary bladder by treating the patient with tolterodine or a tolterodine-related compound, or pharmaceutically...
6770297 Controlled release delivery system of solid dosage form  
This invention relates to a controlled release delivery system of solid dosage form with a plurality of controls on the release of the active ingredient or ingredients.
6762267 Controlled release polyacrylic acid granules and a process for preparing the same  
The present invention pertains to a method for forming polyacrylic acid granules and granules formed therefrom wherein the granules are flowable, have an increased bulk density relative to the as...
6761904 Pharmaceutical kit comprising midodrine as active drug substance  
The invention provides a novel pharmaceutical kit comprising a controlled release pharmaceutical compositions for oral use containing midodrine and/or its active metabolite desglymidodrine. The...
6759064 Compositions based on vanilloid-catechin synergies for prevention and treatment of cancer  
The invention described herein encompasses methods and compositions of preventing or treating cancer comprising the administration of a combination of catechins and vanilloids. Compositions of...
6756056 Treatment of Parkinson's disease and related disorders by novel formulations of the combination carbidopa-levodopa  
An oral antiparkinson drug delivery system consisting of carbidopa and levodopa in immediate and sustained release compartments provides a significant clinical advantage over currently available...
6756057 Amoxicillin and potassium clavulanate dosage form  
Bacterial infections may be treated using a high dosage regimen of amoxicillin and potassium clavulanate. Preferably, the dosage is provided by a bilayer tablet.
6753011 Combined diffusion/osmotic pumping drug delivery system  
Delivery devices capable of delivering one or more active substances by diffusion through plural micropores in the membrane (4) or by osmotic pumping through one or more preformed passageways (5)...
6750249 Controlled release oral preparations of esculetin and its derivatives  
The present invention relates to an oral preparation of esculetin with controlled release. The oral preparation of esculetin with controlled release of the present invention comprises a gel-forming...
6749867 Delivery system for omeprazole and its salts  
The present invention provides a time-release dosage form for delivering an acid-labile pharmaceutical, such as omeprazole, into the upper portion of the gastrointestinal tract downstream of the...
6746692 Modified release pharmaceutical formulation comprising amoxycillin  
Bacterial infections may be treated using a high dosage regimen of amoxycillin and potassium clavulanate. Preferably, the dosage is provided by a bilayer tablet.
6743444 Method of making microencapsulated DNA for vaccination and gene therapy  
A method of making a microparticle that contains DNA coding for a polypeptide is described in which a solvent extraction method is used and solvent extraction takes place at elevated temperature....
6743445 Low temperature coatings  
A method of coating an active material is provided. The method comprises contacting an active material with a film-forming composition comprising an aqueous dispersion of an amylose-alcohol...
6743442 Melt-extruded orally administrable opioid formulations  
Bioavailable sustained release oral opioid analgesic dosage forms, comprising a plurality of multiparticulates produced via melt extrusion techniques are disclosed.
6740340 Pharmaceutical tablets comprising an NSAID and a prostaglandin  
A pharmaceutical tablet which incorporates two smaller tablets, one of which comprises an NSAID and the other of which comprises misoprostol.
6733782 Core tablet for controlled release of gliclazide after oral administration  
The invention relates to a matrix tablet for the prolonged release of gliclazide which ensures continuous and consistent release of the active ingredient after administration by the oral route, the...
6733784 Coated, platform-generating tablet  
An expanding tablet is described comprising a drug release controlling membrane material. After swallowing, the tablet hydrates and expands such that the membrane ruptures to directly expose some...
6730319 Pharmaceutical compositions having depressed melting points  
The present invention relates to pharmaceutical compositions that contain a solid pharmaceutically active compound having a melting point ≧37° C. and a fatty acid or a fatty acid salt or a mi...
6730321 Press coated, pulsatile drug delivery system suitable for oral administration  
A press-coated tablet suitable for oral administration, comprising an immediate-release compartment comprising a compressed blend of an active agent. The immediate-release compartment has a...
6730320 Tetracycline antibiotic product, use and formulation thereof  
An antibiotic product, in particular a tetracycline, such as doxycycline, is comprised of at least three dosages forms, each of which has a different release profile, with the Cmax for the...
6726931 Process for preparing oral sustained-release formulation of felodipine  
The present invention relates to a process for producing an oral sustained-release pharmaceutical composition of felodipine. The process includes mixing together felodipine with at least an ionic...
6726930 Sustained release heterodisperse hydrogel systems for insoluble drugs  
A sustained release pharmaceutical formulation includes a sustained release excipient including a gelling agent, an inert pharmaceutical diluent, an optional cationic cross-linking agent, and a...
6723737 Methods, pharmaceutical and therapeutic compostions for administering adenosine  
The invention discloses methods for the chronic administration of adenosine, which contrary to the acute delivery of the drug by injection or infusion, acts in desensitizing adenosine receptors...
6723341 Antibiotic product, use and formulation thereof  
An antibiotic product is comprised of at least three dosages forms, each of which has a different release profile, with the Cmax for the antibiotic product being reached in less than about twelve...
6723340 Optimal polymer mixtures for gastric retentive tablets  
Unit dosage form tablets for the delivery of pharmaceuticals are formed of the pharmaceutical dispersed in a solid unitary matrix that is formed of a combination of poly(ethylene oxide) and...
6720004 Controlled release formulation of divalproex sodium  
A new oral polymeric controlled release formulation suitable for the once-a-day administration of valproate compounds, such as divalproex sodium, has been discovered. This formulation exhibits...
6713509 Controlled release formulation for treating COPD  
This invention relates to a controlled or sustained release formulation designed to deliver a PDE4 inhibitor for treating an inflammatory disease such as asthma or COPD and the like.
6709669 Fast-dispersing dosage forms containing fish gelatin  
The invention disclosed herein relates to a pharmaceutical composition comprising a carrier and an active ingredient, wherein the carrier is fish gelatin and the composition is a fast-dispersing...
6706284 Bitterness-reduced oral pharmaceutical composition  
The invention relates to an oral pharmaceutical composition which has excellent drug release-controlling ability in the mouth even 5 to 10 minutes after its administration and also has excellent...
6706282 Controlled delivery of phenoxyethyl-substituted 1,2,4-triazolones  
Dosage forms and methods for the controlled release of antidepressives, such as exemplified by phenoxyethyl substituted-1,2,4-triazolones, as a suspension or a slurry over a prolonged period of...
6703045 Composition and method for maintaining blood glucose level  
A composition useful for reducing serum glucose levels by an oral controlled release system and a method for treating diabetes in a human being by controlling the blood glucose level (BGL) and...
6702803 Multi-step drug dosage forms  
Controlled release, multi-step drug dosage forms comprising a plurality of dose units and a plurality of separators that control release of drug from the dose units. In one embodiment, a dose unit...
6699833 Pharmaceutical formulations for sustained drug delivery  
Sustained delivery formulations comprising a water-insoluble complex of a peptide and a carrier macromolecule are disclosed. The formulations of the invention allow for loading of high...
6699508 Sustained release oral preparations of fasudil hydrochloride  
An oral sustained-release preparation which contains at least one active ingredient selected from the group consisting of fasudil hydrochloride and a hydrate thereof is disclosed. A method for...
6699840 Controlled- or delayed-release forms of topiramate  
The invention encompasses novel salts of topiramate, and pharmaceutically acceptable polymorphs, solvates, hydrates, dehydrates, co-crystals, anhydrous, or amorphous forms thereof, as well as...