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6455053 |
Quickly soluble solid preparations
An orally administrable uncompressed rapidly dissolving molded dosage form comprises a drug and either one or more saccharides or one saccharide and polyvinylpyrrolidone. Saccarides are chosen and...
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6451340 |
Nucleotide analog compositions
The invention provides crystalline forms of adefovir dipivoxil and methods to prepare the crystals. The compositions and methods of the present invention have desirable properties for large scale...
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6451343 |
Composition for treating dementia and Alzheimer's disease
Controlled release dosage forms useful in the treatment and/or prophylaxis of dementia, including Alzheimer's disease, in mammals, and for enhancing amyloid precursor protein processing along a...
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6444218 |
Soft chewable multivitamin tablet comprising separated active ingredients
The present invention provides an improved soft chewable multivitamin tablet in which vitamin C is separated from calcium pantothenate and/or minerals such as iron, copper, zinc and mixtures...
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6440450 |
Soft chewable tablet comprising separated active ingredients
The present invention provides an improved soft chewable multivitamin tablet in which vitamin C is separated from calcium pantothenate and/or minerals such as iron, copper, zinc and mixtures...
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6440458 |
Sustained release preparations
Providing an oral formulation of a macrolide compound where the dissolution of the macrolide compound is under sustained release; and a sustained-release formulation containing a composition in...
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6440462 |
Agglomerates of β-lactam antibiotics and processess for making agglomerates
Agglomerates of β-lactam antibiotics, such as penicilllin V potassium, amoxicillin trihydrate, cephalexin monohydrate, which are suitable for direct tablet formation.
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6440459 |
Paroxetine maleate polymorph and pharmaceutical compositions containing it
The form B of paroxetine maleate polymorph is characterized by determined data of X ray diffraction: it has a chemical stability which is superior to that of the form A of paroxetine maleate. This...
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6432447 |
Organic compounds
An oral dosage form comprising fluvastatin and HPMC, which oral dosage form is color-stable upon prolonged periods of storage.
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6432534 |
Process for the production of tablets and tablets
A method for producing tablet including active component, diluting agent, and lubricant by means of a tabletting machine provided with punches and dies, comprising steps of; preparing molding...
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6426090 |
Over-coated product including tableted center and medicament
Methods and products for delivering a medicament or agent to an individual are provided as well as methods for producing the product. The product includes a coating having a medicament or agent....
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6426091 |
Sustained-release theophylline tablet
A theophylline sustained release tablet obtained by coating core granules composed mainly of theophylline with a layer of a coating film composed of a hydrophobic material and a plastic excipient...
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6423341 |
β-lactam antibiotic-containing tablet and production thereof
This invention provides β-lactam antibiotic-containing tablets capable of being orally taken either as such owing to their being small-sized, hence still easily swallowable, or, in the case of...
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6423694 |
Method of treating otitis media with uridine triphosphates and related compounds
A method of promoting drainage of congested middle ear fluid in a subject in need of such treatment is disclosed. The method comprises administering to the middle ear of the subject a uridine...
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6419950 |
Extracts of zanthoxylum bungeanum, and pharmaceutical and cosmetic formulations containing same
The extract of the pericarp of Zanthoxylum bungeanum, prepared by extraction with carbon dioxide in supercritical conditions, has remarkable analgesic activity without exerting the local...
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6420560 |
H1—histamine receptor antagonists
This invention relates to novel multibinding compounds (agents) that are H1 histamine receptor antagonists and pharmaceutical compositions comprising such compounds. Accordingly, the multibinding...
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6419954 |
Tablets and methods for modified release of hydrophilic and other active agents
The invention provides a tablet and methods for making the tablet comprising a gel-forming material and at least one particle comprising an active agent in contact with a coating material to modify...
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6416786 |
Sustained release tablet containing hydrocolloid and cellulose ether
The present invention is directed to a solid sustained release pharmaceutical tablet for administering to a host, comprising a therapeutically effective amount of a pharmaceutically active...
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6413541 |
Disintegrating tablet in oral cavity and production thereof
Method for producing intrabuccally disintegrating tablets, which comprises the following Steps (a), (b) and (c), wherein a medicament is mixed before granulation or tabletting: (a) a step of...
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6399101 |
Stable thyroid hormone preparations and method of making same
Provided is a pharmaceutical preparation of thyroid hormone and a process of making a tablet formulation of the pharmaceutical preparation using direct compression. In a preferred embodiment, the...
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6387411 |
Method for producing dispersible sterol and stanol compounds
A method for preparing sterol/stanol and sterol/stanol ester compositions with improved dispersibility is provided by co-melting the sterol/stanol and/or sterol/stanol ester with highly branched...
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6387389 |
Sustained-release derivatives of hydroxylated analogs of substituted 1-&lsqb 2&lsqb bis(aryl)methoxy&rsqb ethyl&rsqb -piperazines and -homopiperazines and their use
The present invention provides sustained-release derivatives of hydroxylated analogs of substituted 1-[2[bis(aryl)methoxy]ethyl]-piperazines and -homopiperazines, pharmaceutical compositions...
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6387401 |
Use of lipids as adjuvents in the production of solid medicinal forms by the melt extrusion process
Lipids are used as aids in the production of solid drug forms by melt extrusion.
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6387402 |
Pulverulent sorbitol and its process of preparation
The invention relates to a pulverulent sorbitol, characterized in that it exhibits a hygroscopicity value, determined according to a test A, of less than 2%, preferably of less than 1.7%, and a...
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6383517 |
Process for preparing solid formulations of lipid-regulating agents with enhanced dissolution and absorption
A process for preparing a solid formulation of a lipid-regulating agent comprising dissolving said lipid-regulating agent particles in a surfactant solution, premixing an excipient, wet granulating...
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6384020 |
Rapid immediate release oral dosage form
A pharmaceutical composition comprising lactitol and one or more amphetamine salts in a rapid release formulation.
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6383518 |
Phosphate-binding polymer preparations
A tablet containing a phosphate-binding polymer, which has an average particle size of 400 μm or less, contains particles of 500 μm or less in particle size at a ratio of 90% or more and has a...
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6379700 |
Process for manufacturing tablets for the sustained release of active principle(s)
The invention concerns a method for making tablets with active principle sustained-release which consists in: preparing a fluid oil-in-water emulsion; spraying the resulting emulsion on a powder...
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6380356 |
Multivalent polymyxin antibiotics
Disclosed are multibinding compounds which are antibiotics effective against bacterial infections, in particular, Gram-negative bacterial infections. The multibinding compounds of this invention...
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6376481 |
Sterol esters in tableted solid dosage forms
The present invention provides a sterol, stanol or their corresponding acid ester in a form suitable for the manufacture of an oral dosage form. A method for producing the oral dosage form is also...
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6375971 |
Medicament dosing ballistic implant of improved accuracy
Solid dose ballistic projectile for medicating animals which comprises a biologically compatible projectile casing which defines an interior cavity having a wall with a frictionally engagement...
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6372253 |
Rapidly disintegrating methylcellulose tablets
The present invention relates to a novel pharmaceutical composition and process for preparing swallowable methylcellulose tablets that disintegrate rapidly and meet USP disintegration standards in...
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6368625 |
Orally disintegrable tablet forming a viscous slurry
A dosage form which rapidly disintegrates in the mouth and forms a viscous slurry of either microcapsules or a powder is described. The rapidly disintegrating dosage form is meant for direct oral...
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6368622 |
Process for preparing solid formulations of lipid regulating agents with enhanced dissolution and absorption
A process for preparing a solid formulation of a lipid-regulating agent comprising forming a mixture of said lipid-regulating agent with a surfactant; granulating said mixture by melting, mixing,...
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6368627 |
Compositions
A pharmaceutical composition for oral adminstration comprising a film-coated solid dosage form including 3-[2-(dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulph
onamide or a pharmaceutically...
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6365185 |
Self-destructing, controlled release peroral drug delivery system
The present invention relates to tablets which are time-controlled to release active agent at different rates in different regions of the digestive tract in order to maintain a substantially...
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6365201 |
Phytodrug for management of peptic ulcer and methods of preparing and using same
A phytochemical composition for management of peptic ulcer conditions in humans is provided. The composition is a hot water extract of powdered Indigofera arrecta plant leaves. The extract may be...
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6362371 |
β2- adrenergic receptor agonists
The present invention is directed to multibinding compounds which are β2 adrenergic receptor agonists and are therefore useful in the treatment and prevention of respiratory diseases such asthma,...
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6358527 |
Fast-dissolving galanthamine hydrobromide tablet
The present invention is concerned with a fast-dissolving tablet for oral administration comprising as an active ingredient a therapeutically effective amount of galanthamine hydrobromide (1:1) and...
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6358525 |
Sustained release polymer blend for pharmaceutical applications
A pharmaceutical composition has a blend of at least first and second components and a medicament in a sufficient amount to be therapeutic where the first component is hydroxypropylcellulose (HPC)...
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6352720 |
Pharmaceutical formulations comprised of compacted amoxicillin granulates
The present invention discloses tablet formulations, produced by dry roller compaction comprising compacted granulates of a mixture of a medicament and an intra-granular disintegrant. The...
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6350786 |
Stable complexes of poorly soluble compounds in ionic polymers
Stable water-insoluble complexes of poorly soluble compounds molecularly dispersed in water-insoluble ionic polymers are disclosed. Useful insoluble ionic polymers have a molecular weight greater...
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6350476 |
Herbal chinese joint complex
The present invention provides compositions comprising the ingredients of plants of species of the genera Stephania, Coix, Pinellia, Prunus, Phellodendron, Sophora, Tetrapanax, Stemona,...
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6348216 |
Ibuprofen and narcotic analgesic compositions
Provided herein are compositions and methods of making compositions of ibuprofen in combination with a narcotic analgesic. Specifically provided is a pharmaceutical tablet composition comprising...
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6348470 |
Antitussive compositions
The invention relates to the use of theobromine and/or its salts and/or its complexes optionally in admixture with other known active ingredients and inert solid or liquid carriers, additives and...
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6346269 |
Method for preparing an oral formulation containing acid-sensitive drugs and oral formulation made thereby
The present invention relates to a method for preparing an oral formulation containing acid-sensitive drugs, including at least the following step: spreading a solution or a suspension containing...
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6346270 |
Phenytoin therapy
A therapeutic composition, a dosage form and a method are disclosed for administering phenytoin indicated for the management of epilepsy.
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6344216 |
Conversion of powdered polymers
Carbomer or cross-polyacrylate polymers which are conventionally provided in a powdered form are converted to a granulated, pelletized or tablet form for subsequent use, in combination with a...
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6342247 |
Pharmaceutical compositions containing irbesartan
Pharmaceutical compositions containing irbesartan, alone or in combination with a diuretic, providing tablets with a high relative amount of active agent and excellent wetting and disintegration...
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6342245 |
Compositions of lipid lowering agents
The present invention is concerned with novel pharmaceutical compositions of lipid lowering agents which can be administered to a mammal suffering from hyperlipidemia, obesitas or atherosclerosis,...
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