|
Match
|
Document |
Document Title |
|
|
5413572 |
Osmotic dosage system for liquid drug delivery
An osmotic system is disclosed for delivering a beneficial agent formulation to an environment of use. The osmotic system comprises (a) an outside semipermeable wall, (b) a middle osmotically...
|
|
|
5401515 |
Coated active agent-containing article
Aqueous coating compositions for forming elastomeric films around active cores (e.g., drugs) comprising a dispersion of pre-crosslinked polyorganosiloxane latex particles, colloidal silica...
|
|
|
5401512 |
Delayed release oral dosage forms for treatment of intestinal disorders
An orally administrable pharmaceutical dosage form for selectively administering a drug to the intestine comprises a plurality of enteric coated granules of the drug contained in an enterically...
|
|
|
5397573 |
Laxative compositions
Laxative compositions containing sennoside and menthol, pharmaceutically-acceptable esters of menthol, or mixtures thereof, preferably as peppermint oil; and methods for treating constipation by...
|
|
|
5397574 |
Controlled release potassium dosage form
A pharmaceutical composition for oral administration of potassium salt in a form not irritating to the gastrointestinal mucosa comprises tablets or capsules of micropellets of a potassium salt,...
|
|
|
5391377 |
Biphasic release formations for lipophilic acids
A pharmaceutical formulation comprises: (a) a C 12 -C 24 fatty acid, which may be saturated or mono- or poly-unsaturated, such as oleic or linoleic acid; and (b) a generally lipophilic...
|
|
|
5342624 |
Dispensing device
Novel devices for the controlled release of active materials especially pharmaceutical are formed from at least two interpenetrating pieces. The male piece is water swellable and swells to...
|
|
|
5330759 |
Enteric coated soft capsules and method of preparation thereof
Soft capsules coated with an enteric coating comprising a 1:1 copolymer of methacrylic acid and methyl or ethyl acrylate or methyl or ethyl methacrylate and a plasticizer without need for a...
|
|
|
5324280 |
Osmotic dosage system for delivering a formulation comprising liquid carrier and drug
An osmotic system is disclosed for delivering a beneficial agent formulation to an environment of use. The osmotic system comprises (a) an outside semipermeable wall, (b) a middle osmotically...
|
|
|
5318779 |
Drug-impregnated ceramic
A drug-impregnated ceramic to be embedded in a living body is disclosed, and includes a porous ceramic having pores with a pore size of 10 to 300 μm, a drug impregnating the porous ceramic via the...
|
|
|
5314696 |
Methods for making and administering a blinded oral dosage form and blinded oral dosage form therefor
The invention relates to a method for making and administering a blinded oral dosage form and the blinded oral dosage form therefor, used for disguising the identity of tableted medications. The...
|
|
|
5314697 |
Stable extended release oral dosage composition comprising loratadine and pseudoephedrine
A film-coated extended release oral dosage composition containing the nasal decongestant pseudoephedrine sulfate in a unique polymer matrix core and a film-coating on such core containing the...
|
|
|
5296233 |
Dual subcoated simulated capsule-like medicament
A simulated capsule-like medicament comprising a dual subcoating comprising an initial subcoating of a water soluble film forming polymer, e.g. povidone and a secondary subcoating of a mixture of...
|
|
|
5296232 |
Pharmaceutical formulation which does not induce tolerance
A controlled-release organic nitrate formulation for once-per-day oral administration is provided by spheres having a core which includes an organic nitrate, and a membrane surrounding the core...
|
|
|
5294439 |
Stabilized benzimidazole derivative and composition
A stabilized physiologically active benzimidazole derivative having the formula (I): ##STR1## wherein R 1 is hydrogen atom, an alkyl group having 1 to 8 carbon atoms, a fluoroalkyl group having 1...
|
|
|
5283064 |
Large intestinal dissociative hard capsules
A large intestinal dissociative hard capsule comprising a capsule mainly composed of chitosan, the viscosity at 20° C. of a solution obtained by dissolving the chitosan in an aqueous 1% by weight...
|
|
|
5281711 |
(S)-1-[10-chloro-6,7-dihydro-4-oxo-3-phenyl-4H-benzo[a]quino-lizin-1-yl) carbonyl]-3-ethoxypyrrolidine
The compound (S)-1-[(10-chloro-6,7-dihydro-4-oxo-3-phenyl-4H-benzo[a]quin
o-lizin-1-yl)c arbonyl]-3-ethoxypyrrolidine of the formula ##STR1## which has valuable pharmacological properties, is...
|
|
|
5252333 |
Lithium salt-containing pharmaceutical compositions
The invention provides pharmaceutical and disinfectant compositions containing lithium salts of C 18 -22 polyunsaturated fatty acids. The compositions may be used in the treatment of conditions...
|
|
|
5238686 |
Sustained-release pharmaceutical preparation
A sustained-release pharmaceutical preparation comprising an admixture of uncoated and/or single walled water soluble drug, such as aspirin, and dual walled coated drug. The dual wall structure has...
|
|
|
5206219 |
Oral compositions of proteinaceous medicaments
Proteinaceous medicaments such as erythropoetin, insulin and calcitonin are formulated in a medium comprising a polyol pharmaceutical solvent combined as co-solvent with a lipid pharmaceutical...
|
|
|
5194464 |
Enteric film and preparatoin thereof
An enteric film is produced by spraying on a material a mixed solution of (a) hydroxypropylmethylcellulose phthalate exhibiting a viscosity of about 136 to 204 centistokes as 10%...
|
|
|
5185157 |
Treatment of refractory Eosinophilia-Myalgia Syndrome with L-tryptophan composition
A method of treating a human patient with refractory Eosinophilia Myalgia Syndrome via oral administration of an effective dosage range of from 1000 mg. to 3000 mg. of a pharmaceutical composition,...
|
|
|
5178873 |
Essential fatty acid treatment
A method of inhibiting phospholipase A2 in the control of inflammation, wherein delta-6,9,12,15-octadecatetraenoic acid (stearidonic acid) and/or delta-8,11,14,17-eicosatetraenoic acid is...
|
|
|
5164195 |
Method of oral delivery with an adherent controlled-release salt sensitive capsule
A salt sensitive capsule has been developed which dissolves in the mouth and releases the encapsulated internal ingredient(s). The outer salt sensitive shell maintains its integrity when kept at a...
|
|
|
5158776 |
Solid oral dosage forms of ifosfamide
Solid oral ifosfamide formulations comprising a capsule containing a mass which consists essentially of the active substance ifosfamide and microcrystalline cellulose, or in the form of tablets...
|
|
|
5152994 |
Rapid method for interrupting or attenuating poly-drug dependency syndromes
The administration to a poly-drug addict of ibogaine, ibogaine, tabernanthine, alkaloids in the family of apocynaceae, or their non-toxic salts have been discovered to interrupt the physiological...
|
|
|
5151273 |
Delayed-release pharmaceutical preparation
Delayed-release tablets are formed by incorporating hemicellulose and a matrix-forming adjuvant which does not disintegrate in a pharmaceutical dosage form containing the active substance or...
|
|
|
5122384 |
Oral once-per-day organic nitrate formulation which does not induce tolerance
A controlled-release organic nitrate formulation for once-per-day oral administration is provided by spheres having a core which includes an organic nitrate, and a membrane surrounding the core...
|
|
|
5110602 |
Pharmaceutical compositions comprising esters or amides as active ingredients
The present invention relates to new pharmaceutical compositions characterizing that esters or amides are suspended or dissolved in a middle chain glyceride or a mixture thereof. These...
|
|
|
5108759 |
Endothelial envelopment drug carriers
This application describes the preparation and in vivo testing of surface coatings and matrix materials, which when applied to or caused to comprise the carriers for drugs and diagnostic agents,...
|
|
|
5093130 |
Powder coated hydrogel capsules
Methods and materials are provided for coating hydrogel capsules containing botanic tissue with an inert substance that decrease capsule surface adhesiveness and facilitates singulation and...
|
|
|
5077052 |
Chitosan derivatives useful in compositions for coating feedstuff additives intended for ruminants
Novel organosoluble derivatives of chitosan, useful in coating biologically active feedstuff additives intended for ruminants, to provide coatings which are stable at a pH greater than 5 and which...
|
|
|
5064650 |
Controlled-release salt sensitive capsule for oral use and adhesive system
A salt sensitive capsule has been developed which dissolves in the mouth and releases the encapsulated internal ingredient(s). The outer salt sensitive shell maintains its integrity when kept at a...
|
|
|
5064656 |
Uncoated pharmaceutical reaction tablet
An uncoated compressed tablet which is used for the preparation of an orally applicable aqueous suspension or solution of a pharmaceutically active substance contains a mixture of the...
|
|
|
5057322 |
Method of treating mast cell disease
A method of treating a patient suffering from mast cell disease comprising daily administration to such patient of from about 1 to about 150 mg of a pure narcotic antagonist, e.g., nalmefene or...
|
|
|
5032405 |
Oral pharmaceutical composition for acid sensitive proteinaceous agents
An orally administrable formulation of a biologically active, acid sensitive, proteinaceous agent comprises a composition of a lyophilized mixture of the proteinaceous agent and maltose, optionally...
|
|
|
5023083 |
Azarbine composition
A method for treating azaribine-responsive diseases in patient's who exhibit severe pyridoxal phosphate depletion following the oral administration of azaribine comprises first encapsulating...
|
|
|
5015479 |
Sustained release capsule or tablet formulation comprising a pharmaceutically acceptable dihydropyridine
A sustained release capsule or tablet formulation suitable for once-daily administration comprises an adsorbate of a mixture of a pharmaceutically useful dihydropyridine and a polyvinylpyrrolidone...
|
|
|
4981695 |
Composition comprising L-dopa
The present invention relates to a multiple-unit-dose comprising L-dopa as pharmaceutically active compound, whereby the composition provides a release of L-dopa in accordance with a test in...
|
|
|
4965089 |
Method and apparatus for the gelatin coating of caplets
A caplet dipping machine includes a caplet holding plate including sets of caplet gripping collets on both sides thereof so that caplets can be dipped on one end, pushed through the plate and...
|
|
|
4910021 |
Targeted enternal delivery system
A capsule for oral administration of a pharmaceutically active ingredient contains a pharmaceutical composition comprising the active ingredient, for example, a peptide, an absorption promoter and...
|
|
|
4849227 |
Pharmaceutical compositions
A composition adapted to administer a pharmocologically effective amount of a pharmaceutical agent when ingested orally comprising (a) a pharmaceutical agent; (b) a lipid coating materials; and (c)...
|
|
|
4832686 |
Method for administering interleukin-2
A biocompatible, biodegradable, bioerodible composite polymer matrix comprising interleukin-2 in an appropriate polymer. The polymer may be a polymer or copolymer of lactic acid, lactide,...
|
|
|
4816260 |
Personal protection device
A personal protection device having a flexible support, and a breakable capsule at a front surface of the support, which capsule contains skunk essence. Upon attack, the user bends the support to...
|
|
|
4816259 |
Process for coating gelatin capsules
This invention provides a new gelatin capsule formulation and subcoating for producing soft gelatine capsules having better mechanical strength and an improved capacity for adhering to known...
|
|
|
4800056 |
Process for making dispenser with cooperating elements
A method of forming a dispenser for delivering a beneficial agent to a biological environment. A beneficial agent and an expandable composition are placed in a capsule made of fluid dissolvable...
|
|
|
4794000 |
Coacervate-based oral delivery system for medically useful compositions
The present invention provides for an oral drug delivery system based on a two phase liquid coacervate system prepared from water and one or more surfactants selected from anionic, cationic,...
|
|
|
4670287 |
Method of film-coating hard capsules
A method of film-coating hard capsules is provided which comprises subjecting, drug-filled hard capsules to a vacuum to remove air entrapped therein and then coating the evacuated capsules while...
|
|
|
4456628 |
Process for film-coating a particulate solid, and emulsions for conducting the process
A process of coating a particulate medicinal agent; comprising the application to said medicinal agent of a liquid composition containing a water-insoluble film-forming agent, a lipophilic solvent,...
|
|
|
4452862 |
Pharmaceutical coating materials soluble or swellable in gastric juice and pharmaceutical dosage forms coated therewith
Coating materials for pharmaceutical dosage forms contain, besides the conventional liquid or solid additives for pharmaceutical coatings, a binder comprising a synthetic polymer, prepared by...
|