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7618649 |
Extended release oral dosage composition
A bilayer solid composition comprising (a) an immediate release first layer comprising an anti-allergic effective amount of desloratadine and at least one pharmaceutically acceptable excipient and...
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7452868 |
Controlled release formulations of octreotide
A formulation of octreotide or pharmaceutically acceptable salts thereof, which provides controlled release of a therapeutically effective amount of octreotide for a period of at least about two...
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7435715 |
Microcapsules
Microcapsules for use in liquid detergents having a core and a polyelectrolyte complex shell in the form of a semipermeable membrane capable of withstanding a force before bursting of from about 20...
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7431944 |
Delivery of multiple doses of medications
Dosage forms for oral administration of a methylphenidate drug are provided. The dosage forms provide a substantially immediate dose of methylphenidate upon ingestion, followed by one or more...
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7387791 |
Liposome drug delivery
This invention comprises pharmaceutical compositions for administering a biologically active compound to an animal. Particularly provided are proliposomal compositions that are advantageously used...
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7332160 |
Medical device and method for tissue removal and repair
The present invention relates to medical devices that are to be implanted or inserted into the body of a patient for the purpose of removing undesired body tissues. In one embodiment of the...
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7316818 |
Liposome drug delivery of polycyclic, aromatic, antioxidant or anti-inflammatory compounds
This invention comprises pharmaceutical compositions for administering a polycyclic, aromatic, antioxidant or anti-inflammatory compound to an animal. Particularly provided are proliposomal...
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7259139 |
Means for maintenance and/or correction of glucose concentration in blood
The invention relates to preparations that are useful in maintaining mammalian blood glucose concentrations. These preparations contain insulin, and a polymeric matrix. The polymeric matrix has a...
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7211275 |
Composite materials for controlled release of water soluble products
Composite materials comprising a water-soluble compound adsorbed onto a basic inorganic material and a bio-degradable polymer which yields acidic degradation products, methods of producing same,...
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7201921 |
Antihistamine formulations for soft capsule dosage forms
The invention herein relates to a pharmaceutical composition containing loratadine and derivatives thereof which is suitable for use in soft capsule dosage forms. A pharmaceutical composition...
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7195769 |
Pharmaceutical compositions of anti-tubercular drugs and process for their preparation
A pharmaceutical composition of anti-tubercular drugs for oral use comprising Rifampicin and/or Isoniazid wherein the bioavailability of Rifampicin and/or other drugs is enhanced. Preferably the...
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7163694 |
Bioerodible poly(ortho esters) from dioxane-based di(ketene acetals), and block copolymers containing them
Bioerodible poly(ortho esters) useful as orthopedic implants or vehicles for the sustained delivery of pharmaceutical, cosmetic and agricultural agents from dioxane-based di(ketene acetals). Block...
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7160559 |
Controlled release galantamine composition
The present invention is concerned with controlled release compositions for oral administration comprising galantamine; and with processes of preparing such controlled release compositions.
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7157095 |
Multiple-delayed release antifungal product, use and formulation thereof
An anti-fungal product is comprised of at least three delayed release dosages forms, each of which has a different release profile, with the C max for the anti-fungal product being reached in less...
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7101574 |
Pharmaceutical composition containing fenofibrate and the preparation method
The invention concerns a pharmaceutical composition containing micronized fenofibrate, a surfactant and a binding cellulose derivative, as solubilizing adjuvant, preferably...
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7045146 |
Templating of solid particles by polymer multilayers
Process for encapsulation of an uncharged crystalline solid particle include treating the crystalline solid particle material with amphiphilic substances and subsequently coating the material with...
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7011847 |
Enteric coated formulation for bisphosphonic acids and salts thereof
Pharmaceutical compositions and methods of using the composition are provided. The pharmaceutical composition comprises an inert core surrounded by an active coating containing one or more...
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6994873 |
Multiparticulate formulations of lithium salts for oral administration suitable for once-a-day administration
This invention refers to:
multiparticulate formulations of Lithium salts for oral administration constituted by either modified release granules or mixtures of modified and conventional...
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6989159 |
Pharmaceutical compositions containing lithium carbonate
Once daily pharmaceutical compositions containing lithium carbonate in the form of coated granules.
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6958161 |
Modified release coated drug preparation
A modified release preparation having one or more coated core elements, each core element including an active ingredient and having a modified release coating, wherein a stabilising coat is...
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6933380 |
Excipients containing low residual solvent and method for producing the same
The present invention provides low-residual-solvent containing excipients with residual solvent less than <3000 ppm. Most of the excipients are required to first be modified to become more water...
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6932981 |
Rapidly disintegrating sustained release cefuroxime axetil composition
A fast disintegrating controlled release oral composition comprising a core material containing cefuroxime axetil present as controlled release form, the cefuroxime axetil being provided with an...
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6911217 |
Controlled release bead, a method of producing the same and multiple unit formulation comprising it
A controlled release bead comprises: (i) a core unit of a substantially water-soluble or water-swellable inert material; (ii) a first layer on the core unit of a substantially water-insoluble...
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6884433 |
Sustained release formulation containing tacrolimus
Sustained release formulation containing tacrolimus or its hydrate is provided. The time (T63.2%) required for 63.2% of the maximum amount of tacrolimus or its hydrate to be dissolved is 0.7 to 15...
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6884432 |
Blend, cross-linkable poly(propylene fumarate) for immobilization and controlled drug delivery
Microspheres for controlled release of a bioactive agent are disclosed, and in particular, blend, cross-linkable poly(propylene fumarate) for immobilization and controlled drug delivery. The...
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6861068 |
Pharmaceutical compositions using semi-solid delivery vehicle
A semi-solid delivery vehicle contains a polyorthoester and an excipient, and a semi-solid pharmaceutical composition contains an active agent and the delivery vehicle. The pharmaceutical...
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6849271 |
Microcapsule matrix microspheres, absorption-enhancing pharmaceutical compositions and methods
The present invention relates to microspheres, processes for the manufacture of said microspheres, pharmaceutical compositions comprising said microspheres, and sustained release methods of...
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6849269 |
Proliposomal drug delivery system
This invention relates to proliposomal drug-delivery systems for medicaments. In particular, it relates to enteric-coated proliposomal formulations for poorly water soluble drugs and methods for...
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6828334 |
Fenofibrate-cyclodextrin inclusion complexes and their pharmaceutical composition
The present invention relates to pharmaceutical compositions containing fenofibrate in the form of an inclusion complex with cyclodextrin, having high dissolution profile and in vivo enhanced...
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6824791 |
Methods for micronization of hydrophobic drugs
The invention involves methods and products related to the micronization of hydrophobic drugs. A method of micronizing hydrophobic drugs using a set of solutions including an aqueous solution is...
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6780436 |
Solid oral pharmaceutical formulation of modified release that contains an acid labile benzimidazole compound
The pharmaceutical formulation consists of a number of pellets that comprise an inert nucleus, a layer with the active ingredient, one or more intermediate layers that comprise at least a system of...
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6713509 |
Controlled release formulation for treating COPD
This invention relates to a controlled or sustained release formulation designed to deliver a PDE4 inhibitor for treating an inflammatory disease such as asthma or COPD and the like.
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6699501 |
Polyelectrolyte coverings on biological templates
The invention relates to a method for producing capsules provided with a polyelectrolyte covering, and to the capsules obtained using this method.
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6685962 |
Gastroretentive controlled release pharmaceutical dosage forms
Pharmaceutical gastroretentive drug delivery systems for the controlled release of an active agent in the gastrointestinal tract are disclosed, which comprise: (a) a single- or multi-layered matrix...
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6673814 |
Delivery systems and methods for noscapine and noscapine derivatives, useful as anticancer agents
The present invention relates to methods useful for the treatment of neoplastic diseases, tumor cells, and the treatment of cancer delivering compounds of the formula The invention provides...
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6660296 |
Sustained-release microgranules containing diltiazem as active principle
Novel forms of sustained-release microgranules (LP) containing diltiazem are disclosed. The microgranules consist of a neutral granular carrier coated with an active layer including diltiazem or a...
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6635277 |
Composition for pulsatile delivery of diltiazem and process of manufacture
A once-a-day controlled release drug delivery system of diltiazem hydrochloride is provided, which is bioequivalent in plasma profile of Cardizem CD. The fast, medium, and slow release fractions...
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6632454 |
Multilayer pharmaceutical product for release in the colon
The invention relates to the use of a multilayer pharmaceutical product that substantially comprises a) a core containing a pharmaceutically active substance, b) an inner coating consisting of a...
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6630162 |
Pharmaceutical formulation and its use
The invention relates to a pharmaceutical formulation containing tolterodine or a tolterodine-related compound, or a pharmacologically acceptable salt thereof, as active ingredient, in which the...
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6630156 |
Process for preparing biodegradable microspheres containing physiologically active agents
The present invention relates to a process for preparing biodegradable microspheres containing physiologically active agents. Particularly, the present invention relates to the process comprised...
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6627219 |
Oily capsule preparation and the method for preparing same
The present invention provides a oral capsule preparation, comprising a capsule prepared from a drug or the alkaline salt thereof, an oily compound or the alkaline salt thereof, an emulsifier and a...
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6620431 |
Shellac film coatings providing release at selected pH and method
Film coatings for enteric and colonic release at selected pH are provided by selecting and/or formulating a shellac of a predetermined acid number. The method includes the selection of the acid...
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6613355 |
Semi-solid delivery vehicle and pharmaceutical compositions
A semi-solid delivery vehicle contains a polyorthoester and an excipient, and a semi-solid pharmaceutical composition contains an active agent and the delivery vehicle. The pharmaceutical...
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6607747 |
High drug load acid labile pharmaceutical composition
A high drug load spheronized beadlet is provided wherein said beadlet comprises about 80% to 100% by weight of an acid labile medicament, preferably didanosine, about 0% to about 10% by weight of a...
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6586010 |
Method for producing agglomerates comprising a core-shell structure
A process for producing agglomerates with a core/shell structure, in which i) initial agglomerates containing a first particulate solid are prepared; ii) a second particulate solid is agglomerated...
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6576260 |
Sustained-release form of administration containing tramadol saccharinate
Disclosed herein is sustained-release formulations of tramadol comprising tramadol saccharinate coated with at least one sustained-release coating. The sustained release formulations may also...
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6576258 |
Pharmaceutical formulation with controlled release of active substances
There is disclosed a method for stabilizing active substances that are unstable in acidic medium, unstable when stored for longer periods of time in the presence of water and at the same time...
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6576255 |
Injection molding method for (meth)acrylate copolymers having tertiary ammonium groups
The invention relates to a process for making molded articles by means of injection molding with the process steps of a) melting of a (meth)acrylate copolymer, which is composed of 30 to 80 wt % of...
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6569452 |
Pharmaceutical formulations in hydroxypropylmethylcellulose capsules
An oral pharmaceutical formulation, which comprises, in a hydroxypropylmethylcellulose capsule, a camptothecin analogue dispersed or solubilized in a semi-solid matrix of a polyethyleneglycol with...
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6555137 |
Sucralfate-containing composition and process for the preparation thereof
A coated antacid comprising sucralfate and an antacid inhibits decline in the adhesion characteristics of sucralfate whereby the drug ingested can reliably show its effect in the stomach. This...
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