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7521067 |
Methods and apparatus for determining formulation orientation of multi-layered pharmaceutical dosage forms
Rapid and accurate determination of the formulation orientation of multi-layer capsule-shaped tablets with respect to different internal formulation layers proximate to the opposite narrow and...
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7510727 |
Melt-extrusion multiparticulates
A unit dose sustained-release oral dosage form containing a plurality of melt-extruded particles, each consisting essentially of a therapeutically active agent, one or more retardants, and an...
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7452868 |
Controlled release formulations of octreotide
A formulation of octreotide or pharmaceutically acceptable salts thereof, which provides controlled release of a therapeutically effective amount of octreotide for a period of at least about two...
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7338942 |
Composition and method for maintaining healthy mobile joints and cartilage
Compositions and methods for maintaining healthy mobile joints and cartilage in humans and animals are disclosed. The composition comprises glucosamine and chondroitin dispersed in a...
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7338931 |
Hydrophobic biomolecular structure
The present invention relates to a new hydrophobe biomolecular structure, which is compacted due to the passing of the structure over its point of collapse, a method for the preparation of the...
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7264824 |
Oral dosage form
Oral dosage form for food and food supplement as well as dietetics comprising polyunsaturated acids in a xylose-hardened gelatine capsule with a retarded release time.
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7217431 |
Controlled agglomeration
A process for the preparation of a particulate material by a controlled agglomeration method, i.e. a method that enables a controlled growth in particle size. The method is especially suitable for...
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7122207 |
High drug load acid labile pharmaceutical composition
A high drug load spheronized beadlet is provided wherein said beadlet comprises about 80% to 100% by weight of an acid labile medicament, preferably didanosine, about 0% to about 10% by weight of a...
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7060293 |
Powder-layered oral dosage forms
An oral dosage form of morphine is formulated by powder-layering an homogeneous mixture of morphine sulfate and hydrous lactose impalpable onto inert beads to obtain a multiparticulate product. A...
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7045146 |
Templating of solid particles by polymer multilayers
Process for encapsulation of an uncharged crystalline solid particle include treating the crystalline solid particle material with amphiphilic substances and subsequently coating the material with...
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7022683 |
Pharmacological compositions comprising pectins having high molecular weights and low degrees of methoxylation
The inventions disclosed herein relate to compositions for the sustained release of pharmacological agents comprising pectins having a combination of both a high molecular weight and a low degree...
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RE39030 |
Fluoxetine enteric pellets and methods for their preparation and use
A superior enteric formulation of the antidepressant drug, fluoxetine, is in the form of enteric pellets of which the enteric layer comprises hydroxypropylmethylcellulose acetate succinate.
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7011847 |
Enteric coated formulation for bisphosphonic acids and salts thereof
Pharmaceutical compositions and methods of using the composition are provided. The pharmaceutical composition comprises an inert core surrounded by an active coating containing one or more...
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7008639 |
Fish gelatin compositions containing a hydrocolloid setting system
The invention concerns Gelatin compositions for the use in pharmaceutical, veterinary, food, cosmetic or other products like films for wrapping food, aspics or jellies, preferably for predosed...
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6994873 |
Multiparticulate formulations of lithium salts for oral administration suitable for once-a-day administration
This invention refers to:
multiparticulate formulations of Lithium salts for oral administration constituted by either modified release granules or mixtures of modified and conventional...
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6989159 |
Pharmaceutical compositions containing lithium carbonate
Once daily pharmaceutical compositions containing lithium carbonate in the form of coated granules.
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6984449 |
Pellets and process for production thereof
The invention relates to pellets and a production process therefor. Pellets comprise at least one oily component, which is either an active component alone or comprises such an active component....
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6972132 |
System for release in lower digestive tract
A system whereby a substance which is orally taken and to be delivered into the lower digestive tract is selectively delivered into the lower digestive tract. More particularly, a system which...
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6958161 |
Modified release coated drug preparation
A modified release preparation having one or more coated core elements, each core element including an active ingredient and having a modified release coating, wherein a stabilising coat is...
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6933380 |
Excipients containing low residual solvent and method for producing the same
The present invention provides low-residual-solvent containing excipients with residual solvent less than <3000 ppm. Most of the excipients are required to first be modified to become more water...
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6926938 |
Hardshell gelatin capsule reducing the static electricity and enhancing the lubrication of film
The present invention provides a process for preparing hardshell gelatin capsule reducing the static electricity and enhancing the lubrication of film having good film distribution in capsule...
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6926910 |
Hydrophobe biomolecular structure
The present invention relates to a new hydrophobe biomolecular structure, which is compacted due to the passing of the structure over its point of collapse, a method for the preparation of the...
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6926906 |
Orally administrable pharmaceutical formulation
The present invention relates to a pharmaceutical formulation for oral administration through a soft gelatin capsule drug delivery device, wherein the pharmaceutical formulation has Pseudoephedrine...
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6911217 |
Controlled release bead, a method of producing the same and multiple unit formulation comprising it
A controlled release bead comprises: (i) a core unit of a substantially water-soluble or water-swellable inert material; (ii) a first layer on the core unit of a substantially water-insoluble...
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6849271 |
Microcapsule matrix microspheres, absorption-enhancing pharmaceutical compositions and methods
The present invention relates to microspheres, processes for the manufacture of said microspheres, pharmaceutical compositions comprising said microspheres, and sustained release methods of...
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6849269 |
Proliposomal drug delivery system
This invention relates to proliposomal drug-delivery systems for medicaments. In particular, it relates to enteric-coated proliposomal formulations for poorly water soluble drugs and methods for...
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6835397 |
Controlled release encapsulated bioactive substances
The present invention is an encapsulated yeast composite comprising a core comprising yeast and a coating containing an emulsifiable lipid. The yeast includes Saccharomyces cerevisiae . The...
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6783771 |
Physiologically active substance EEM-S originating in mushrooms, process for producing the same and drugs
EEM-S obtained by extracting with hot water or a lower alcohol at least one mushroom selected from among Lentinus edodes, Flammulina velutipes, Hypsizygus marmoreus, Pleurotus ostreatus, Pholiota...
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6780436 |
Solid oral pharmaceutical formulation of modified release that contains an acid labile benzimidazole compound
The pharmaceutical formulation consists of a number of pellets that comprise an inert nucleus, a layer with the active ingredient, one or more intermediate layers that comprise at least a system of...
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6776985 |
Encapsulated cells producing viral particles
The present invention relates to encapsulated cells producing viral particles, especially retroviral particles containing the genome of a retroviral vector carrying therapeutic genes, to methods...
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6767899 |
Composition and method for treatment of conditions having an inflammatory component
Compositions and methods of treatment for conditions in humans and animals which have an inflammatory component, are disclosed. The composition comprises a glucosamine component dispersed in a...
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6753333 |
Chiral fluoroquinolone arginine salt forms
The invention relates to the new arginine salt forms of S-(−)-9-fluoro-6,7-dihydro-8-(4-hydroxypiperidin-1-yl)-5-m
ethyl-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid, a process for their...
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6750249 |
Controlled release oral preparations of esculetin and its derivatives
The present invention relates to an oral preparation of esculetin with controlled release. The oral preparation of esculetin with controlled release of the present invention comprises a gel-forming...
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6706284 |
Bitterness-reduced oral pharmaceutical composition
The invention relates to an oral pharmaceutical composition which has excellent drug release-controlling ability in the mouth even 5 to 10 minutes after its administration and also has excellent...
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6699501 |
Polyelectrolyte coverings on biological templates
The invention relates to a method for producing capsules provided with a polyelectrolyte covering, and to the capsules obtained using this method.
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6680069 |
Low-substituted hydroxypropyl cellulose and process for manufacturing the same
Processes for manufacturing a low-substituted hydroxypropyl cellulose are described that include dipping pulp into an alkaline solution to prepare an alkali cellulose, reacting the alkali cellulose...
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6673814 |
Delivery systems and methods for noscapine and noscapine derivatives, useful as anticancer agents
The present invention relates to methods useful for the treatment of neoplastic diseases, tumor cells, and the treatment of cancer delivering compounds of the formula The invention provides...
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6664267 |
Crystalline fluoroquinolone arginine salt form
The invention relates to the new arginine salt forms of RS-(±)-9-fluoro-6,7-dihydro-8-(4-hydroxypiperidin-1-yl)-5-m
ethyl-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid,...
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6663901 |
Pellets having a core coated with an antifungal and a polymer
The present invention is concerned with pellets comprising a 710-1180 μm (16-25 mesh) sugar core, a coating film of a water-soluble polymer and an antifungal agent, and a seal coating layer...
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6645525 |
Ionically formulated biomolecule microcarriers
Compositions for sustained delivery of a biomolecule including an anionic polymer and a cationic polymer which ironically interact with each other and, optionally, with the biomolecule. Methods for...
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6635277 |
Composition for pulsatile delivery of diltiazem and process of manufacture
A once-a-day controlled release drug delivery system of diltiazem hydrochloride is provided, which is bioequivalent in plasma profile of Cardizem CD. The fast, medium, and slow release fractions...
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6630162 |
Pharmaceutical formulation and its use
The invention relates to a pharmaceutical formulation containing tolterodine or a tolterodine-related compound, or a pharmacologically acceptable salt thereof, as active ingredient, in which the...
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6627219 |
Oily capsule preparation and the method for preparing same
The present invention provides a oral capsule preparation, comprising a capsule prepared from a drug or the alkaline salt thereof, an oily compound or the alkaline salt thereof, an emulsifier and a...
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6627188 |
Method of reducing bacterial enteropathogens in the crop of fowl subjected to feed withdrawal
A method for reducing bacterial enteropathogens in fowl subjected to feed withdrawal, involving withdrawing feed from fowl and orally administering to the fowl an effective amount of a cocktail...
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6607747 |
High drug load acid labile pharmaceutical composition
A high drug load spheronized beadlet is provided wherein said beadlet comprises about 80% to 100% by weight of an acid labile medicament, preferably didanosine, about 0% to about 10% by weight of a...
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6596308 |
Controlled release pharmaceutical composition
A sustained/prolonged release pharmaceutical dosage form is disclosed. The form comprises a hard shell capsule and a formulation comprising (a) a water insoluble medicant, (b) a high melting fatty...
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6592895 |
Biodegradable polyhydric alcohol esters
Precursor polyhydric alcohol esters where acyl moieties originate from aliphatic homopolymer or copolymer polyesters and contain free hydroxyl at their terminal ends, are reacted to provide...
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6586010 |
Method for producing agglomerates comprising a core-shell structure
A process for producing agglomerates with a core/shell structure, in which i) initial agglomerates containing a first particulate solid are prepared; ii) a second particulate solid is agglomerated...
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6576260 |
Sustained-release form of administration containing tramadol saccharinate
Disclosed herein is sustained-release formulations of tramadol comprising tramadol saccharinate coated with at least one sustained-release coating. The sustained release formulations may also...
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6576258 |
Pharmaceutical formulation with controlled release of active substances
There is disclosed a method for stabilizing active substances that are unstable in acidic medium, unstable when stored for longer periods of time in the presence of water and at the same time...
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