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Document Title |
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8182792 |
Pharmaceutical compositions
A process for micronization of pharmaceutically active agents.
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8182838 |
Dry powder composition comprising co-jet milled particles for pulmonary inhalation
The present invention relates to particles and to methods of making particles. In particular, the invention relates to methods of making composite active particles comprising a pharmaceutically...
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8182791 |
Formulations for use in inhaler devices
A formulation for an inhaler device comprises carrier particles having a diameter of at least 50 μm and a mass median diameter of at least 175 μm; active particles; and additive material to which i...
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8173107 |
Delivery of antipsychotics through an inhalation route
The present invention relates to the delivery of antipsychotics through an inhalation route. Specifically, it relates to aerosols containing antipsychotics that are used in inhalation therapy. In a...
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8168223 |
Engineered particles and methods of use
Engineered particles are provided may be used for the delivery of a bioactive agent to the respiratory tract of a patient. The particles may be used in the form of dry powders or in the form of...
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8158109 |
Foamable suspension gel
The present subject matter provides foamable suspension gels that foam after release from a container. The foamable suspension gels contain at least one pharmaceutically active agent that is...
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8158110 |
Use of aerosolized cyclosporine for prevention and treatment of pulmonary disease
The present invention relates to methods and compositions for prevention of graft rejection in lung transplant recipients and for treatment of subjects with pulmonary disorders. Specifically, the...
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8153104 |
Pharmaceutical formulations for dry powder inhalers comprising a low-dosage strength active ingredient
The invention provides a formulation to be administered as dry powder for inhalation suitable for efficacious delivery of low-dosage strength active ingredients to the low respiratory tract of...
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8137683 |
Process for the preparation of dispersions
The present invention relates to a process of a dispersion of an active substance or composition in a aqueous phase which comprises dispersing in an aqueous phase a solution of such substance or...
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8137657 |
Carrier particles for use in dry powder inhalers
In a method of producing particles suitable for use as carrier particles in dry powder inhalers, particles (1) of a size suitable for use as carrier particles in dry powder inhalers are treated so...
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8129364 |
Formulations and methods for treating rhinosinusitis
The invention involves methods and formulations for treating or preventing rhinosinusitis, including fungus-induced rhinosinusitis in mammals. In one embodiment, the formulation of the present...
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8124128 |
Amphiphilic block copolymers and nano particles comprising the same
An amphiphilic block copolymer. The amphiphilic block copolymer includes one or more hydrophilic polymers, one or more hydrophobic polymer, and one or more zwitterions. The invention also provides...
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8119105 |
Aerosol container and a method for storage and administration of a pre-determined amount of a pharmaceutically active aerosol
The invention relates to an aerosol container for pharmaceutically active aerosols that are to be administered in predetermined amounts and that are supplied in the container in the form of a...
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8114438 |
DPI formulation containing sulfoalkyl ether cyclodextrin
An inhalable dry powder formulation containing SAE-CD and an active agent is provided. The formulation is adapted for administration by DPI. The SAE-CD serves as a carrier rather than as an...
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8101160 |
Formulations for use in inhaler devices
A formulation for use in an inhaler device comprises carrier particles having a diameter of at least 50 μm and a mass median diameter of at least 175 μm; fine particles of an excipient material h...
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8092785 |
Process for milling poorly soluble drugs in presence of liquid propellants
Drug substance for use in a pharmaceutical formulation may be prepared by a process which process comprises co-milling a suspension of the drug substance and a pharmaceutically acceptable polymer...
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8080236 |
Particulate materials
Embodiments of the invention relate to particles of active substances, methods for preparing the particles, formulations containing the particles, and metered dose inhalers containing the particles...
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8075873 |
Method of preparing dry powder inhalation compositions
The invention provides a method of preparing a dry powder inhalation composition comprising a pharmaceutically acceptable particulate carrier, a first particulate inhalant medicament and a second...
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8074644 |
Method of forming an aerosol for inhalation delivery
The present invention relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to a method of forming an aerosol for use in inhalation therapy. In a...
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8071074 |
Preventing airway mucus production by administration of EGF-R antagonists
Hypersecretion of mucus in the lungs is inhibited by the administration of an epidermal growth factor receptor (EGF-R) antagonist. The EGF-R antagonist may be in the form of a small organic...
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8062670 |
Compositions exhibiting improved flowability
Powder compositions exhibiting improved flow properties. The compositions generally contain a bulk solid material in the form of a powder and surface-modified nanoparticles. Methods of improving...
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8062626 |
Stable pharmaceutical budesonide preparation for producing propellant-free aerosols
The invention relates to ethanol-containing pharmaceutical preparations for the production of propellant-free aerosols.
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8062627 |
Methods and compositions for treating pulmonary disorders using optically pure (R,R)-formoterol
A method and composition are disclosed utilizing the pure (R,R) isomer of formoterol, which is a potent bronchodilator with reduced adverse effects, a low incidence of the development of tolerance...
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8048451 |
Pharmaceutical compositions for inhalation
The invention provides microparticles for use in a pharmaceutical composition for pulmonary administration, each microparticle comprising a particle of an active substance having, on its surface,...
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8034817 |
Treatment of bacterial diseases of the respiratory organs
The invention relates to inhalable quinolonecarboxylic acid derivative compositions for local control of diseases of the respiratory organs, in particular of lung diseases.
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8029768 |
Treatment of respiratory diseases
A pharmaceutical composition for pulmonary delivery comprises glycopyrrolate in a controlled release formulation, wherein, on administration, the glycopyrrolate exerts its pharmacological effect...
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8022082 |
Method for the administration of an anticholinergic by inhalation
An inhalation kit comprising: (a) an inhaler displaying a flow resistance of about 0.01 to 0.1 √{square root over (kPa)} min/L; and (b) an inhalable powder comprising tiotropium in admixture with a...
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8017237 |
Nanoshells on polymers
Nano-constructs comprising nanoshells and methods of using the nano-constructs for treating or ameliorating a medical condition are provided.
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8003081 |
Method for improvement of tolerance for therapeutically effective agents delivered by inhalation
A method for improvement of tolerance for therapeutically effective agents delivered by inhalation comprising a pretreatment of a patient with a nebulized lidocaine or a lidocaine-like compound...
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8003080 |
Delivery of drug amines through an inhalation route
The present invention relates to the delivery of drug amines through an inhalation route. Specifically, it relates to aerosols containing drug amines that are used in inhalation therapy. In one...
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8001961 |
Container for inhalation anesthetic
A container for liquid inhalation anesthetics, more particularly, an aluminum container that is suitable for storing halogenated inhalation anesthetics is described.
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7998463 |
Targeted delivery of lidocaine and other local anesthetics and a method for treatment of cough, asthma and tussive attacks
An anti-tussive nebulized solution for targeted delivery of lidocaine into conducting and central airways. A method for treatment of cough and tussive attacks or episodes using said lidocaine...
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7988952 |
Delivery of drug esters through an inhalation route
The present invention relates to the delivery of drug esters through an inhalation route. Specifically, it relates to aerosols containing drug esters that are used in inhalation therapy. In a...
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7972627 |
Beclomethasone dipropionate monohydrate nasal pharmaceutical formulations and methods of using the same
Nasal pharmaceutical formulations comprising a drug substance having a specific particle size distribution profile are disclosed herein. Such profile provides increased bioavailability, increased...
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7972626 |
Fluticasone propionate nasal pharmaceutical formulations and methods of using same
Nasal pharmaceutical formulations comprising a drug substance having a specific particle size distribution profile are disclosed herein. Such profile provides increased bioavailability, increased...
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7954491 |
Low dose pharmaceutical powders for inhalations
The invention relates to a method of delivering an agent to the pulmonary system of a compromised patient, in a single breath-activated step, comprising administering a particle mass comprising an...
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7951401 |
Stabilised solid drug dispersions in an organic carrier and a process for preparing the same
New solid drug dispersions are described in which a drug is present in amorphous form and dispersed within the particles of an organic carrier selected from cross-linked polymers and/or complexing...
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7947308 |
Effervescent powders for inhalation
Effervescent powders comprising inhalable particles are disclosed, as are methods for preparing these powders. The inhalable carrier particles comprise an inorganic or organic carbonate, and an...
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7947742 |
Inhalable epinephrine
The present invention is directed toward particles for delivery of epinephrine to the respiratory system and methods for treating a patient in need of epinephrine. The particles and respirable...
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7947744 |
Stable pharmaceutical products
Provided herein is a stable pharmaceutical product comprising a dry powder inhalation device, and a pharmaceutical composition that comprises R,R-Formoterol L-tartrate salt, in particular...
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7943178 |
Methods and compositions for delivering peptides
Methods are provided for purifying peptides and proteins by incorporating the peptide or protein into a diketopiperazine or competitive complexing agent to facilitate removal one or more...
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7943118 |
Aerosolized fosfomycin/aminoglycoside combination for the treatment of bacterial respiratory infections
A fosfomycin plus tobramycin combination formulation for delivery by aerosolization is described. The concentrated fosfomycin tobramycin combination formulation containing an efficacious amount of...
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7914770 |
Formulation for a metered dose inhaler using hydro-fluoro-alkanes as propellants
An improved suspension formulation for use in a metered-dose inhaler having a hydro-fluoro-alkane propellant is described, the improvement being the controlled addition of a small quantity of water.
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7914771 |
Treatment of chronic obstructive pulmonary disease by low dose inhalation of protease inhibitor
The present invention encompasses methods and compositions for the treatment and prevention of chronic obstructive pulmonary disease (COPD) or emphysema, typically smoking-induced emphysema. More...
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7892781 |
Detecting a target using a composite probe comprising a directing agent, a metal nanoparticle and an enzyme
A test agent includes a composite probe having at least one nanoparticle having multiple metal atoms, a directing agent, and an enzyme. The directing agent attaches the probe to a target in a test...
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7879358 |
Pulmonary delivery for levodopa
In one aspect, the invention is related to a method of treating a patient with Parkinson's disease, the method including administering to the respiratory tract of the patient particles that include...
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7846462 |
Personal care implement containing a stable reactive skin care and cleansing composition
Skin care or cleansing implements are described containing a liquid, semi-solid or solid cleansing or skin treatment composition that is releasably associated with the implement. The composition is...
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7842284 |
Odor eliminating items and methods of use for hunting
A regimen for hunting includes using a number of zeolite-containing personal items in connection with a hunter's apparel and body to reduce the hunter's scent for improved hunting. The personal...
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7807200 |
Formulations for spray-drying large porous particles
Particles having a tap density less than about 0.4 g/cm3 are formed by spray drying from a colloidal solution including a carboxylic acid or salt thereof, a phospholipid, a divalent salt and a...
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7790145 |
Respiratory dispersion for metered dose inhalers
A respiratory dispersion is provided for the pulmonary delivery of at least two bioactive agents. The dispersion comprises a propellant suspension medium having dispersed therein a plurality of...
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