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7601337 |
Delivery of antipsychotics through an inhalation route
The present invention relates to the delivery of antipsychotics through an inhalation route. Specifically, it relates to aerosols containing antipsychotics that are used in inhalation therapy. In a...
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7601336 |
Pharmaceutical aerosol composition
A composition for use in an aerosol inhaler, the composition comprising an active material, a propellant containing a hydrofluoroalkane (HFA), a cosolvent and further comprising a low volatility...
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7591999 |
Powdery preparation for nasal administration
According to the present invention, a powdery preparation for nasal administration comprising a physiologically active substance, a non-water-absorbing and hardly water-soluble powder(s) and one or...
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7585493 |
Thin-film drug delivery article and method of use
An article for use in an aerosol device, for producing an aerosol of a drug composition is disclosed. The article includes a heat-conductive substrate having a surface with a selected surface area,...
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7582284 |
Particulate materials
The present invention relates to active substances in particulate form, to methods for preparing them, to formulations containing them and to uses of such substances and formulations. A preferred...
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7566445 |
Medicinal aerosols and methods of delivery thereof
This invention provides a medicinal aerosol formulation comprising a particulate medicament, a fluorocarbon propellant and 6% to 25% w/w of the total formulation of a polar co-solvent, wherein the...
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7556798 |
Highly efficient delivery of a large therapeutic mass aerosol
A method for delivering an agent to the pulmonary system, in a single, breath-activated step or a single breath, comprises administering from a receptacle enclosing a mass of particles, to a...
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7544367 |
Chemical method of making a suspension, emulsion or dispersion of pyrithione particles
A method for producing a suspension, emulsion or dispersion of de-agglomerated particles (advantageously submicron-sized particles) of pyrithione salts comprising contacting agglomerated pyrithione...
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7541022 |
Pharmaceutical formulations for dry powder inhalers
A powder for use in a dry powder inhaler comprises: i) a fraction n of fine particle size constituted by a mixture of physiologically acceptable excipient and an additive; ii) a fraction of coarse...
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7537009 |
Method of forming an aerosol for inhalation delivery
The present invention relates to the inhalation delivery of aerosols containing small particles. Specifically, it relates to a method of forming an aerosol for use in inhalation therapy. In a...
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7524484 |
Delivery of diphenhydramine through an inhalation route
The present invention relates to the delivery of diphenhydramine through an inhalation route. In a composition aspect of the present invention, a composition of a diphenhydramine condensation...
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7521068 |
Dry powder aerosols of nanoparticulate drugs
There invention discloses aqueous dispersions of nanoparticulate aerosol formulations, dry powder nanoparticulate aerosol formulation, propellant-based aerosol formulations, methods of using the...
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7510702 |
Delivery of nonsteroidal antiinflammatory drugs through an inhalation route
The present invention relates to the delivery of nonsteroidal antiinflammatory drugs (NSAIDs) through an inhalation route. Specifically, it relates to aerosols containing NSAIDs that are used in...
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7507745 |
Pharmaceutical compositions based on fluorenecarboxylic acid esters and soluble TNF receptor fusion proteins
The present invention relates to novel pharmaceutical compositions based on fluorene carboxylic acid ester derived anticholinergics of formula 1
and soluble TNF receptor fusion proteins,...
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7507398 |
Delivery of physiologically active compounds through an inhalation route
The present invention relates to the delivery of physiologically active compounds through an inhalation route. Specifically, it relates to aerosols containing physiologically active compounds that...
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7507397 |
Delivery of muscle relaxants through an inhalation route
The present invention relates to the delivery of muscle relaxants through an inhalation route. Specifically, it relates to aerosols containing muscle relaxants that are used in inhalation therapy....
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7507396 |
Effervescent composition and method of making an effervescent composition including a viscous component
Disclosed is an effervescent composition and a method of making an effervescent composition that includes a viscous component and is a free flowing granulation.
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7498020 |
Medicaments
This invention relates to aerosol formulations of use for the administration of medicaments by inhalation, in particular a pharmaceutical aerosol formulation which comprises particulate salbutamol...
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7498019 |
Delivery of compounds for the treatment of headache through an inhalation route
The present invention relates to the delivery of migraine headache drugs through an inhalation route. Specifically, it relates to aerosols containing migraine headache drugs that are used in...
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7491047 |
Delivery of antihistamines through an inhalation route
The present invention relates to the delivery of antihistamines through an inhalation route. Specifically, it relates to aerosols containing antihistamines that are used in inhalation therapy. In a...
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7488469 |
Delivery of caffeine through an inhalation route
The present invention relates to the delivery of caffeine through an inhalation route. Specifically, it relates to aerosols containing caffeine that are used in inhalation therapy. In a composition...
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7481995 |
Aerosol composition
An aerosol composition comprising a propellant and a first particulate material comprising particles having a median aerodynamic diameter with the range 0.05 to 11 μm, such as a medicament...
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7479481 |
Treatment of ocular diseases and disorders using lantibiotic compositions
Compositions and methods for treating ocular diseases and disorders are provided. The composition can contain at least one lantibiotic, which can be administered topically by injection,...
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7476380 |
Methods for treating illnesses of the tracheo-bronchial tract, especially chronic obstructive pulmonary disease (COPD)
The invention describes a means for the treatment of diseases of the tracheo-bronchial tract, particularly of COPD.
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7473416 |
Medicaments for asthma treatment
A method and apparatus are disclosed for treating asthma and other respiratory conditions. A medicament comprising a surface active phospholipid (SAPL) is prepared in the form of a fine powder and...
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7470421 |
Delivery of diazepam through an inhalation route
The present invention relates to the delivery of compounds for the treatment of anxiety disorders and symptoms of such disorders through an inhalation route. Specifically, it relates to aerosols...
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7469488 |
Control of process humidity to produce large, porous particles
Spray dried particles having specified aerodynamic characteristics are produced by atomizing a liquid feed and contacting the liquid feed with a drying gas, such as, for example, air or nitrogen....
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7468179 |
Delivery of opioids through an inhalation route
The present invention relates to the delivery of opioids through an inhalation route. Specifically, it relates to aerosols containing opioids that are used in inhalation therapy. In a method aspect...
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7465436 |
Delivery of compounds for the treatment of Parkinson's through an inhalation route
The present invention relates to the delivery of antiparkinsons drugs through an inhalation route. In a method aspect of the present invention, an antiparkinsons drug is administered to a patient...
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7465435 |
Delivery of beta-blockers through an inhalation route
The present invention relates to aerosols containing of atenolol, pindolol, esmolol, propranolol, or metoprolol that are used in inhalation therapy. In a method aspect of the present invention, of...
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7459146 |
Stabilized aerosol dispersions
The invention relates to stabilized dispersions containing nanoparticles of use for the administration of medicaments. The dispersions comprise excipient nanoparticles, a dispersed phase comprising...
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7449201 |
Storage stable power compositions of interleukin-4 receptor
The present invention provides storage stable dry powder compositions of IL-4R. The powder compositions demonstrate superior chemical and physical stability over their solution counterparts,...
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7449174 |
Delivery of analgesics through an inhalation route
The present invention relates to the delivery of analgesics through an inhalation route. Specifically, it relates to aerosols containing acetaminophen, orphenadrine or tramadol that are used in...
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7449172 |
Delivery of antiemetics through an inhalation route
The present invention relates to the delivery of antiemetics through an inhalation route. Specifically, it relates to aerosols containing antiemetics that are used in inhalation therapy. In a...
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7445768 |
Delivery of sedative-hypnotics through an inhalation route
The present invention relates to the delivery of sedative-hypnotics through an inhalation route. Specifically, it relates to aerosols containing sedative-hypnotics that are used in inhalation...
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7442388 |
Phospholipid-based powders for drug delivery
Phospholipid based powders for drug delivery applications are disclosed. The powders comprise a polyvalent cation in an amount effective to increase the gel-to-liquid crystal transition temperature...
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7442368 |
Delivery of stimulants through an inhalation route
The present invention relates to the delivery of stimulants through an inhalation route. Specifically, it relates to aerosols containing stimulants that are used in inhalation therapy. In a method...
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7435408 |
Porous particles comprising excipients for deep lung delivery
Improved porous particles for drug delivery to the pulmonary system, and methods for their synthesis and administration are provided. In a preferred embodiment, the porous particles are made of a...
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7431916 |
Administration of medicinal dry powders
A method of administering a metered dry powder combined dose of finely divided dry medication powders is disclosed, wherein said method comprises providing a relative motion between a nozzle of a...
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7427607 |
Drug administration method
A method of administering a drug whereby a fine drug powder can be accurately administered to a target site (in particular, a target site in the body cavity) via fluidization and spraying with a...
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7417051 |
Medicaments comprising betamimetics and a novel anticholinergic
A pharmaceutical composition comprising:
(a) a salt of formula 1
wherein:
X − is an anion with a single negative charge; and (b) a betamimetic 2,
or a solvate or hydrate thereof,...
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7405207 |
Nebulizer formulations of dehydroepiandrosterone and methods of treating asthma or chronic obstructive pulmonary disease using compositions thereof
This invention relates to a sealed container containing a powder formulation comprising a dehydroepiandrosterone, its analogue(s) or salt(s) by itself or with a pharmaceutically or veterinarily...
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7399528 |
Powder particles with smooth surface for use in inhalation therapy
Carrier particles, for use in the preparation of powdery mixtures for administration by inhalation, and having a median diameter of greater than 90 microns and a surface rugosity expressed as the...
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7393544 |
Dispersion for pulmonary delivery of a bioactive agent
Stabilized dispersions are provided for the delivery of a bioactive agent. The dispersions preferably comprise a plurality of perforated microstructures dispersed in a suspension medium that...
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7368104 |
Treatment of respiratory diseases
A pharmaceutical composition for pulmonary delivery comprises glycopyrrolate in a controlled release formulation, wherein, on administration, the glycopyrrolate exerts its pharmacological effect...
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7368102 |
Pulmonary delivery of aminoglycosides
The present invention is directed to the administration of aminoglycosides. In particular, the present invention is directed to compositions and methods for the pulmonary administration of...
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7364749 |
Preparations for the application of anti-infective and/or anti-inflammatory agents
Use of an anti-infective and/or anti-inflammatory agent for the preparation of a pharmaceutical composition for the treatment of diseases of external or internal parts of the human or animal body...
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7354966 |
Compounds for use as surfactants
Compounds of formula (I):
and uses of such compounds are described.
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RE40045 |
Medicaments
Pharmaceutical compositions comprising effective amounts of salmeterol (and a physiologically acceptable salt thereof) and fluctuations propionate as a combined preparation for simultaneous,...
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7317070 |
Process for the preparation of polyamino acids
Among the various aspects of the present invention is an improved process for the preparation of polyamino acids generally, and more specifically, polyglutamic acid and polyaspartic acid. Another...
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