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6846801 |
Systemic administration of a therapeutic preparation
A method of treating a patient in need of insulin treatment, including the steps of introducing into the lower respiratory tract of the patient an effective amount of a therapeutic preparation in...
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6838076 |
Pulmonary administration of chemically modified insulin
The present invention provides active, hydrophilic polymer-modified derivatives of insulin. The insulin derivatives of the invention are, in one aspect, suitable for delivery to the lung and...
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6811767 |
Liquid droplet aerosols of nanoparticulate drugs
There invention discloses aqueous dispersions of nanoparticulate aerosol formulations, dry powder nanoparticulate aerosol formulation, propellant-based aerosol formulations, methods of using the...
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6811768 |
Use of inhaled NO as anti-inflammatory agent
A method for lessening or preventing non-pulmonary ischemia-reperfusion injury or inflammation in a mammal by identifying a mammal which has ischemia-reperfusion or is at risk for developing...
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6803031 |
Delivery of erectile dysfunction drugs through an inhalation route
The present invention relates to the delivery of erectile dysfunction drugs through an inhalation route. Specifically, it relates to aerosols containing erectile dysfunction drugs that are used in...
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6797258 |
Compositions and methods for the pulmonary delivery of aerosolized macromolecules
According to the subject invention, dispersible dry powder pharmaceutical-based compositions are provided, including methods for their manufacture and dry powder dispersion devices. A dispersible...
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6797281 |
Esters of I-carnitine or alkanoyl I-carnitines
Esters of L-carnitine and alkanoyl L-carnitines are described which can be used as cationic lipids for the intracellular delivery of pharmacologically active compounds. New esters of L-carnitine...
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6793912 |
Treatment of cancers by inhalation of stable platinum-containing formulations
Disclosed are methods of treating cancers by inhalation of stable platinum-containing formulations.
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6780398 |
Aqueous nasal formulation
An aqueous nasal formulation comprising beclomethasone dipropionate anhydrate for use in the treatment of respiratory disorders.
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6780881 |
Freeze-dried pantoprazole preparation and pantoprazole injection
Lyophilized pantoprazole preparations which are obtainable by freeze-drying of an aqueous solution of pantoprazole, ethylenediamine tetraacetic acid and/or a suitable salt thereof, and sodium...
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6767901 |
Ciclesonide contained pharmaceutical composition for application to mucosa
The present invention provides a pharmaceutical composition for application to the mucosa to be used in drug therapy comprising a water-insoluble and/or water-low soluble substance, ciclesonide,...
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6756033 |
Method for delivering benzindene prostaglandins by inhalation
A method of delivering benzindene prostaglandins to a patient by inhalation is discussed. A benzindene prostaglandin known as UT-15 has unexpectedly superior results when administered by inhalation...
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6752988 |
Method of treating upper resiratory illnesses
A method for the prophylactic and therapeutic treatment of bacterial infections is disclosed which comprises the treatment of an individual with an effective amount of a native or modified version...
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6749845 |
Modulated release particles for lung delivery
A polymeric construct is disclosed. The construct comprises a polysaccharide polymer having a selected medicament associated therewith. The medicament thus present is provided in a slow release form.
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6740307 |
Delivery of β-blockers through an inhalation route
The present invention relates to the delivery of beta-blockers through an inhalation route. Specifically, it relates to aerosols containing atenolol, pindolol, esmolol, propranolol, or metoprolol...
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6740306 |
Imidazotriazinone-containing compositions for nasal administration
The present invention relates to imidazotriazinone-containing compositions for nasal administration which, besides the cGMP PDE inhibitor, contain a small amount of a local anaesthetic.
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6719960 |
Use of phospholipids for the manufacture of a medicament for the prevention of adhesions
A medicament is disclosed for reducing the risk of cross-healing (“adhesions”) after surgery. The medicament is a dry powder comprising a surface active phospholipid which is capable of binding...
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6713047 |
Pharmaceutical aerosol composition containing HFA 227 and HFA 134a
In a solution composition for use in an aerosol inhaler which comprises an active material, a propellant containing a hydrofluoroalkane, a cosolvent and optionally a low volatility compound the use...
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6709670 |
Aminoethanesulfonic acid-containing preparations
Preparations to be applied to the oral or nasal cavity which contain aminoethanesulfonic acid and a mucosal stimulant. When these preparations are applied to the oral or nasal cavity,...
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6709650 |
Spray-dried microparticles and their use as therapeutic vehicles
Microparticles of a water-soluble material, which are smooth and spherical, and at least 90% of which have a mass median particle size of 1 to 10 μm, and which carry a therapeutic or diagnostic...
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6703010 |
Spray containing amphoteric material to reduce malodors
Powder compositions usable to reduce malodours, and powder formulations from which can be made aqueous spray compositions usable to reduce malodours, each comprise, as a major ingredient,...
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6702997 |
Albuterol inhalation solution, system, kit and method for relieving symptoms of pediatric asthma
The present invention relates to an albuterol inhalation solution, system, kit and method for relieving bronchospasm in children suffering from asthma. In one alternative embodiment, the solution...
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6699459 |
Methods of treating lung inflammation
The present invention relates to a method of treating lung inflammation in a subject which includes administering butylated hydroxyanisol to the subject in an amount effective to treat lung...
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6685955 |
Odor eliminating items and methods of use for hunting
A regimen for hunting includes using a number of activated carbon-containing personal items in connection with a hunter's apparel and body to reduce the hunter's scent for improved hunting. The...
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6660249 |
Inhalable dry powder aztreonam for treatment and prevention of pulmonary bacterial infections
A method and a composition for treatment of pulmonary bacterial infections caused by gram-negative bacteria suitable for treatment of infection caused by Escherichia coli, Klebsiella pneumoniae,...
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6656453 |
Medicaments
This invention relates to aerosol formulations of use for the administration of medicaments by inhalation. More particularly, the invention relates to a pharmaceutical aerosol formulation which...
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6652838 |
Method for treating diabetes mellitus
A method for treating postprandial hyperglycemia in diabetes mellitus in a human which employs a combination of an aerosolizable topical insulin and a short-acting oral hypoglycemic agent as a...
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6652837 |
Preparation of novel particles for inhalation
Particles incorporating a surfactant and/or a hydrophilic or hydrophobic complex of a positively or negatively charged therapeutic agent and a charged molecule of opposite charge for drug delivery...
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6645468 |
Medicinal aerosol formulation
This invention relates to medicinal aerosol and more formulation and more particularly, to a medicinal aerosol formulation containing rosiglitazone maleate and a fluid carrier.
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6645467 |
Composition and method for decreasing upper respiratory airway resistance
A composition, process and method is disclosed of decreasing mammalian upper respiratory system airway resistance by administering an aerosolized mixture of lipid crystals comprised of a mixture of...
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6645469 |
Method for dispensing S-adenosyl-methionine in a micro fine powdered form by inhalation
A method is provided for dispensing dry micro powdered SAMe compositions (or SAM or AdoMet), an abbreviation for S-adenosyl-methionine, wherein SAMe, as active ingredient is contained in an amount...
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6641800 |
Pressurized aerosol compositions comprising powdered medicament dispersed in hydrofluoroalkane
Pressurized aerosol composition for administration by inhalation comprising a liquefied hydrofluoroalkane, a powdered medicament dispersed therein, and a suspending agent comprising a polymer...
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6638495 |
Stabilized preparation for use in metered dose inhalers
Stabilized dispersions are provided for the delivery of a bioactive agent to the respiratory tract of a patient. The dispersions preferably comprise a plurality of perforated microstructures...
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6632842 |
Albuterol and ipratropium inhalation solution, system, kit and method for relieving symptoms of chronic obstructive pulmonary disease
The present invention relates to a dual bronchodilator inhalation solution, system, kit and method for relieving bronchospasm in patients suffering from chronic obstructive pulmonary disease...
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6623723 |
Method for treating bronchial constriction and bronchospasm
The present invention is directed to a method for treating bronchial constriction in mammals. The method comprises contacting mammalian lung with a compound selected from the group consisting of...
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6616945 |
Method for making a pharmaceutical formulation
The invention concerns a method for preparing a physically stable and homogeneous powdered preparation containing particles of an active agent. The particles are suspended in a suspending agent in...
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6616914 |
Method for pulmonary and oral delivery of pharmaceuticals
In a powder formulation for use in a dry powder inhaler, a pharmaceutical acts as its own carrier, so that use of lactose or other excipients are not needed. The dry powder formulation has a single...
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6613307 |
Aerosol formulations of salmeterol xinafoate
The present invention relates to formulations comprising particulate products which may be prepared by methods and apparatus using supercritical fluids. More particularly, the invention relates to...
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6610273 |
Process for making chemically stable C-17/21 OH 20-ketosteroid aerosol products
A medicinal aerosol steroid solution formulation product with enhanced chemical stability. The steroid is a 20-ketosteroid having an OH group at the C-17 or C-21 position and the aerosol container...
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6592848 |
Mixtures of oxygen and helium for the treatment of respiratory insufficiency
The invention relates to a ready-to-use binary gaseous mixture containing 63.1 to 69.9% by volume of helium and the remainder being oxygen, preferably a mixture of 65% of helium and of 35% of...
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6592879 |
Diaper dermatitis preventative medication and a method for making and using same
The invention discloses a composition for the prevention and treatment of diaper dermatitis which includes an effective amount of an anti-lipase agent and/or an anti-protease agent in a suitable...
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6589559 |
Nasally administrable compositions
A nasally administrable composition of a physiologically active substance, wherein an effective amount of said physiologically active substance is dispersed homogeneously in and adsorbed...
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6582677 |
Propellant compositions of a particulate medicament that are free of solvents
Pressurized aerosol composition comprising a liquefied hydrofluorocarbon propellant of formula C x H y F z where x is an integer from 1 to 3, y+z=2x+2, and y and z are both at least 1; from 0.01...
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6582728 |
Spray drying of macromolecules to produce inhaleable dry powders
According to the subject invention, dispersible dry powder pharmaceutical-based compositions are provided, including methods for their manufacture and dry powder dispersion devices. A dispersible...
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6576224 |
Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
Pharmaceutical compositions are described that comprise one or more active ingredients selected from the group consisting of anti-infective, anti-inflammatory and mucolytic agents, and particularly...
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6572893 |
Systems and processes for spray drying hydrophobic drugs with hydrophilic excipients
Methods for preparing dry powders having hydrophobic and hydrophilic components comprise combining solutions of the components and spray drying them simultaneously in a spray dryer. The hydrophilic...
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6558651 |
Aerosols containing annealed particulate salbutamol and tetrafluoroethane
This invention relates to aerosol formulations of use for the administration of medicaments by inhalation. More particularly, the invention relates to a pharmaceutical aerosol formulation which...
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6555675 |
Dinucleoside polyphosphate compositions and their therapuetic use as purinergic receptor agonists
The present invention relates to certain novel dinucleotide polyphosphates of general Formulae I, II and III, and formulations thereof which are selective agonists of the P2Y purinergic receptors....
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6544497 |
Modulated release particles for aerosol delivery
A modulated release aerosol formulation is disclosed. The formulation comprises a polymer, e.g. silica gel, fumed silica gel, having a selected medicament associated therewith, a fluid carrier for...
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6544542 |
Fat emulsions for inhalational administration
The object of the present invention is to provide a pharmaceutical composition optimized for the administration of a drug, particularly a drug which is only sparingly soluble in water, by way of...
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