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8173158 |
Methods of treating gastrointestinal disorders independent of the intake of food
The present invention relates to a method of treating a gastrointestinal disorder by administering to a patient in need of treatment thereof a pharmaceutical composition, wherein said...
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8062663 |
Methods and compostions for enhancing transdermal drug delivery
Methods and compositions for enhancing transdermal delivery of a bioactive agent. The method contains the step of applying to a skin tissue an effective amount of a composition comprising: (a) a...
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7858118 |
Extended release composition containing Tramadol
An oral Tramadol-containing pharmaceutical composition suitable for once daily administration, which contains an amount of Tramadol or a pharmaceutically acceptable salt thereof, providing in vivo,...
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7776614 |
Test method for determining compounds capable of quenching electronic singlet state excitation of photoactive compounds
A method of testing a compound for its capability of quenching singlet excited state energy from a photon-excited photoactive compound, thereby photostabilizing said photoactive compound,...
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7771750 |
Controlled release oral dosage form
A once a day bupropion hydrochloride formulation is disclosed.
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7767708 |
Growth stimulant compositions
An improved weight and growth stimulant for domesticated animals such as cattle, pigs and sheep is comprised of an anabolic agent that is subcutaneously administered in the form of a dual release...
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7740881 |
Method of treating humans with opioid formulations having extended controlled release
Solid controlled-release oral dosage forms comprising a therapeutically effective amount of an opioid analgesic or a salt thereof which provide an extended duration of pain relief of about 24...
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7678364 |
Particles for inhalation having sustained release properties
The invention generally relates to a method for pulmonary delivery of therapeutic, prophylactic and diagnostic agents to a patient wherein the agent is released in a sustained fashion, and to...
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7465462 |
Multiparticulate controlled release selective serotonin reuptake inhibitor formulations
A multiparticulate controlled release selective serotonin reuptate inhibitor (SSRI) formulation for oral administration is provided. The formulation includes particles of an SSRI or a...
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7374781 |
Sustained release formulations containing acetaminophen and tramadol
A sustained release formulation as a unit dose contains 100 mg-1000 mg of Acetaminophen and 15 mg-150 mg of tramadol hydrochloride, which comprises of 1) an immediate release portion comprising of...
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7316818 |
Liposome drug delivery of polycyclic, aromatic, antioxidant or anti-inflammatory compounds
This invention comprises pharmaceutical compositions for administering a polycyclic, aromatic, antioxidant or anti-inflammatory compound to an animal. Particularly provided are proliposomal...
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7264824 |
Oral dosage form
Oral dosage form for food and food supplement as well as dietetics comprising polyunsaturated acids in a xylose-hardened gelatine capsule with a retarded release time.
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7217431 |
Controlled agglomeration
A process for the preparation of a particulate material by a controlled agglomeration method, i.e. a method that enables a controlled growth in particle size. The method is especially suitable for...
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7160559 |
Controlled release galantamine composition
The present invention is concerned with controlled release compositions for oral administration comprising galantamine; and with processes of preparing such controlled release compositions.
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7122207 |
High drug load acid labile pharmaceutical composition
A high drug load spheronized beadlet is provided wherein said beadlet comprises about 80% to 100% by weight of an acid labile medicament, preferably didanosine, about 0% to about 10% by weight of a...
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7108861 |
Environmentally benign crop protection agents
Disclosed are environmentally benign crop protection compounds that interfere with the attachment of a broad range of plant pathogens to plant cells surfaces.
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7101574 |
Pharmaceutical composition containing fenofibrate and the preparation method
The invention concerns a pharmaceutical composition containing micronized fenofibrate, a surfactant and a binding cellulose derivative, as solubilizing adjuvant, preferably...
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7025988 |
Liposomes
Liposomes containing lipophilic active ingredient are produced by dehydrating a mixture of liposomes, lipophilic active ingredient and sugar, usually followed by a rehydration step to form...
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7019106 |
Lactic acid polymer and process for producing the same
A process for producing a lactic acid polymer of 15,000 to 50,000 in weight-average molecular weight, the content of polymeric materials having not more than about 5,000 in weight-average molecular...
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RE39030 |
Fluoxetine enteric pellets and methods for their preparation and use
A superior enteric formulation of the antidepressant drug, fluoxetine, is in the form of enteric pellets of which the enteric layer comprises hydroxypropylmethylcellulose acetate succinate.
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6994873 |
Multiparticulate formulations of lithium salts for oral administration suitable for once-a-day administration
This invention refers to: multiparticulate formulations of Lithium salts for oral administration constituted by either modified release granules or mixtures of modified and conventional release...
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6958161 |
Modified release coated drug preparation
A modified release preparation having one or more coated core elements, each core element including an active ingredient and having a modified release coating, wherein a stabilising coat is...
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6911217 |
Controlled release bead, a method of producing the same and multiple unit formulation comprising it
A controlled release bead comprises: (i) a core unit of a substantially water-soluble or water-swellable inert material; (ii) a first layer on the core unit of a substantially water-insoluble...
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6878387 |
Coated medicament forms with controlled active substance release
The invention relates to a pharmaceutical preparation consisting of: (a) a core containing an active substance, optionally an excipient and common pharmaceutical additives in addition to the salt...
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6849269 |
Proliposomal drug delivery system
This invention relates to proliposomal drug-delivery systems for medicaments. In particular, it relates to enteric-coated proliposomal formulations for poorly water soluble drugs and methods for...
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6849271 |
Microcapsule matrix microspheres, absorption-enhancing pharmaceutical compositions and methods
The present invention relates to microspheres, processes for the manufacture of said microspheres, pharmaceutical compositions comprising said microspheres, and sustained release methods of...
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6824791 |
Methods for micronization of hydrophobic drugs
The invention involves methods and products related to the micronization of hydrophobic drugs. A method of micronizing hydrophobic drugs using a set of solutions including an aqueous solution is...
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6822000 |
Bioerodible poly (orthoesters) from dioxolane-based diketene acetals
Bioerodible poly(orthoesters) useful as orthopedic implants or vehicles for the sustained delivery of pharmaceutical, cosmetic and agricultural agents contain hydrogen bonding groups and α-hydroxy ...
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6780436 |
Solid oral pharmaceutical formulation of modified release that contains an acid labile benzimidazole compound
The pharmaceutical formulation consists of a number of pellets that comprise an inert nucleus, a layer with the active ingredient, one or more intermediate layers that comprise at least a system of...
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6780427 |
Reduction of adhesions using controlled delivery of active oxygen inhibitors
SOD and other active oxygen inhibitors are directly applied in combination with a barrier material at local sites of tissue injury to prevent or decrease formation of adhesions and undesirable...
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6770619 |
Lung surfactant compositions with dynamic swelling behavior
Lung surfactant compositions are provided which can form a swelling phase when dispersed in a medium containing electrolytes. Hereby, a more active spreading of the lung surfactant into the alveoli...
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6750249 |
Controlled release oral preparations of esculetin and its derivatives
The present invention relates to an oral preparation of esculetin with controlled release. The oral preparation of esculetin with controlled release of the present invention comprises a gel-forming...
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6733767 |
Liquid polymeric compositions for controlled release of bioactive substances
Controlled release of hydrophobic bioactive substances in vivo over an extended time period and without “bursts” of drug release is achieved using a liquid polymeric composition including a pol...
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6685962 |
Gastroretentive controlled release pharmaceutical dosage forms
Pharmaceutical gastroretentive drug delivery systems for the controlled release of an active agent in the gastrointestinal tract are disclosed, which comprise: (a) a single- or multi-layered matrix...
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6673814 |
Delivery systems and methods for noscapine and noscapine derivatives, useful as anticancer agents
The present invention relates to methods useful for the treatment of neoplastic diseases, tumor cells, and the treatment of cancer delivering compounds of the formula The invention provides various...
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6663888 |
Pulsatile release histamine H2 antagonist dosage form
A unit dosage form, such as a capsule or the like, for delivering drugs into the body in a circadian release fashion comprising one or more populations of drug-containing particles (beads, pellets,...
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6660296 |
Sustained-release microgranules containing diltiazem as active principle
Novel forms of sustained-release microgranules (LP) containing diltiazem are disclosed. The microgranules consist of a neutral granular carrier coated with an active layer including diltiazem or a...
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6645524 |
Oral pharmaceutical dosage forms for pulsatile delivery of an antiarrhythmic agent
Novel pharmaceutical dosage forms provide for pulsatile delivery of an antiarrhythmic agent that releases the drug in spaced apart “pulses.” The dosage forms are comprised of first, second and opt...
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6630162 |
Pharmaceutical formulation and its use
The invention relates to a pharmaceutical formulation containing tolterodine or a tolterodine-related compound, or a pharmacologically acceptable salt thereof, as active ingredient, in which the...
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6620431 |
Shellac film coatings providing release at selected pH and method
Film coatings for enteric and colonic release at selected pH are provided by selecting and/or formulating a shellac of a predetermined acid number. The method includes the selection of the acid...
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6555136 |
Pharmaceutical dosage form for pulsatile delivery of methylphenidate
Novel pharmaceutical dosage forms provide for pulsatile delivery of methylphenidate, i.e., release encapsulated drug in spaced apart “pulses.” The dosage forms are comprised of first, second and...
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6479034 |
Method of preparing gas and gaseous precursor-filled microspheres
Methods of and apparatus for preparing temperature activated gaseous precursor-filled liposomes are described. Gaseous precursor-filled liposomes prepared by these methods are particularly useful,...
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6468559 |
Enteric coated formulation of bishosphonic acid compounds and associated therapeutic methods
Oral dosage forms are provided for the administration of a bisphosphonic acid compound in the prevention and treatment of conditions involving calcium or phosphate metabolism, i.e., conditions...
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6436438 |
Tramadol multiple unit formulations
A multiple unit oral pharmaceutical dosage form having a plurality of pellets in a water soluble capsule or in a tablet compressed from the pellets, wherein each pellet contains (a) a substantially...
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6419951 |
Sustained releasing drug comprising copolymers and process for preparing the same
A sustained releasing drug which includes an effective component and a copolymer having a weight-average molecular weight of 1,000 to 100,000 which comprises, as repeating structure units, both of...
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6407057 |
Ovulation triggering drugs
The invention relates to medicaments for initiating ovulation comprising LH in an administrable form which ensures an increase in LH plasma levels for a period of some 40 to 60 hours.
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6403120 |
Extended release formulation of venlafaxine hydrochloride
This invention relates to a 24 hour extended release dosage formulation and unit dosage form thereof of venlafaxine hydrochloride, an antidepressant, which provides better control of blood plasma...
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6379688 |
Preservative for emulsion and emulsion containing same
A preservative for emulsion, comprising sorbic acid or a pharmaceutically acceptable salt thereof, and, where necessary, sodium edetate and boric acid; an emulsion comprising sorbic acid or a...
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6344215 |
Methylphenidate modified release formulations
A pharmaceutical MR (modified release) multiparticulate dosage form such as a capsule (once-a-day MR Capsule) of Methylphenidate indicated for the treatment of children with attention deficit...
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6306900 |
Enteric coated pharmaceutical compositions
This invention provides a pharmaceutical composition comprising a mycophenolate salt, the composition being adapted to release mycophenolate in the upper part of the intestinal tract.
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