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7575743 |
Compositions and methods for the treatment and repair of defects or lesions in articular cartilage using synovial-derived tissue or cells
Compositions and methods are provided for treatment of cartilage defects in animals and humans. The compositions of the invention include synovial tissue, synovial cells and matrices containing...
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7541347 |
Minocycline oral dosage forms for the treatment of acne
Minocycline oral dosage forms containing a controlled release carrier are useful for the treatment of acne.
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7524515 |
Pharmaceutical safety dosage forms
Pharmaceutical safety dosage forms are provided which include a pharmaceutical and an antagonist to the pharmaceutical. The safety dosage forms are such that the antagonist has no significant...
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7470435 |
Extended release venlafaxine formulation
A controlled release dosage form of venlafaxine that comprises an immediate release pellet and an extended release pellet.
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7455864 |
Melatonin-based composition for improved sleep
A method for improving sleep in an individual comprising the administration of a composition comprising melatonin, lavender flower extract and Ferula extract is provided. The composition may be...
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7431944 |
Delivery of multiple doses of medications
Dosage forms for oral administration of a methylphenidate drug are provided. The dosage forms provide a substantially immediate dose of methylphenidate upon ingestion, followed by one or more...
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7427413 |
Stable shaped particles of crystalline organic compounds
The present invention provides storage stable, shaped particles of allotropic organic compounds. The particles of the present invention can be shaped according to the desired application. Preferred...
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7422758 |
Sustained release vitamin composition
A therapeutic formulation in the form of a beadlet, suitable for oral administration and adapted to provide immediate and sustained release of therapeutic material. Each beadlet comprises an...
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7419686 |
Opioid agonist/antagonist combinations
The invention is directed in part to oral dosage forms comprising a combination of an orally analgesically effective amount of an opioid agonist and an orally active opioid antagonist, the opioid...
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7387791 |
Liposome drug delivery
This invention comprises pharmaceutical compositions for administering a biologically active compound to an animal. Particularly provided are proliposomal compositions that are advantageously used...
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7384653 |
Oral dosage form comprising a therapeutic agent and an adverse-effect agent
The present invention provides an oral dosage form comprising a first composition and a second composition. The first composition comprises an effective amount of a therapeutic agent and the second...
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7374781 |
Sustained release formulations containing acetaminophen and tramadol
A sustained release formulation as a unit dose contains 100 mg-1000 mg of Acetaminophen and 15 mg-150 mg of tramadol hydrochloride, which comprises of 1) an immediate release portion comprising of...
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RE40300 |
Carbon dioxide enhancement of inhalation therapy
The present invention provides a method of increasing the deposition of aerosolized drug in the respiratory tract of an individual or animal, comprising the step of administering said aerosolized...
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7348026 |
Nanoparticles for targeting hepatoma cells
The invention discloses the nanoparticles composed of γ-PGA-PLA block copolymers conjugated with galactosamine as a potential drug delivery system for treating liver cancers.
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7320802 |
Methods of treatment using nanoparticulate fenofibrate compositions
The present invention is directed to fibrate compositions having improved pharmacokinetic profiles and reduced fed/fasted variability. The fibrate particles of the composition have an effective...
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7316818 |
Liposome drug delivery of polycyclic, aromatic, antioxidant or anti-inflammatory compounds
This invention comprises pharmaceutical compositions for administering a polycyclic, aromatic, antioxidant or anti-inflammatory compound to an animal. Particularly provided are proliposomal...
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7314640 |
Formulation and process for drug loaded cores
The present invention relates to a controlled release pellet of metoprolol and its pharmaceutically acceptable salts that uses a water soluble or a water swellable inert starting seed or core.
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7303765 |
Ultrafine-L-carnitine, methods of preparing the same, compositions containing the same, and methods of using the same
L-carnitine which has a particle size such that it substantially passes through a 100 USBS mesh sieve exhibits an increased bioavailability, a decreased hygroscopicity, and may be conveniently...
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7276249 |
Nanoparticulate fibrate formulations
The present invention is directed to fibrate compositions having improved pharmacokinetic profiles and reduced fed/fasted variability. The fibrate particles of the composition have an effective...
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7217431 |
Controlled agglomeration
A process for the preparation of a particulate material by a controlled agglomeration method, i.e. a method that enables a controlled growth in particle size. The method is especially suitable for...
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7211275 |
Composite materials for controlled release of water soluble products
Composite materials comprising a water-soluble compound adsorbed onto a basic inorganic material and a bio-degradable polymer which yields acidic degradation products, methods of producing same,...
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7208460 |
Multi component controlled delivery system for soap bars
The present invention relates to an improved controlled delivery system that can be incorporated in soap bars to enhance deposition of active ingredients and sensory markers onto skin. The carrier...
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7195769 |
Pharmaceutical compositions of anti-tubercular drugs and process for their preparation
A pharmaceutical composition of anti-tubercular drugs for oral use comprising Rifampicin and/or Isoniazid wherein the bioavailability of Rifampicin and/or other drugs is enhanced. Preferably the...
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7186418 |
Composition and use of RAR antagonists for promoting chondrogenesis
The invention provides compositions comprising an RAR antagonist for promoting chondrogenesis and methods employing such compositions for treating cartilage and associated bone abnormalities...
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7157103 |
Pharmaceutical formulation containing irritant
Disclosed in certain embodiments is an oral dosage form comprising a therapeutically effective amount of a drug susceptible to abuse; and an effective amount of an irritant to impart an irritating...
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7153840 |
Aqueous fludarabine phosphate composition
This invention is directed towards a ready-to-use aqueous composition of fludarabine phosphate. In one embodiment, the invention is directed to an aqueous fludarabine phosphate composition which...
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7148207 |
Oral fludara of high-purity formulation with quick release of active ingredient
This invention relates to a quick-release tablet formulation with >99.19% pure fludara (high-purity fludara) as an active ingredient in a defined composition of residual contaminants.
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7144587 |
Pharmaceutical formulation containing opioid agonist, opioid antagonist and bittering agent
Disclosed in certain embodiments is an oral dosage form comprising a therapeutically effective amount of an opioid analgesic; an opioid antagonist; and a bittering agent in an effective amount to...
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7141250 |
Pharmaceutical formulation containing bittering agent
Disclosed in certain embodiments is an oral dosage form comprising a therapeutically effective amount of a drug susceptible to abuse; and an effective amount of a bittering agent to impart a bitter...
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7122207 |
High drug load acid labile pharmaceutical composition
A high drug load spheronized beadlet is provided wherein said beadlet comprises about 80% to 100% by weight of an acid labile medicament, preferably didanosine, about 0% to about 10% by weight of a...
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7108866 |
Chronotherapeutic diltiazem formulations and the administration thereof
A controlled-release Galenical preparation of pharmaceutically acceptable Diltiazem including the pharmaceutically acceptable salts thereof, suitable for evening dosing every 24 hours containing...
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RE39239 |
Methods for treating early morning pathologies
The present invention provides methods of treating early morning pathologies using a time-specific controlled release dosage formulation which is administered prior to sleep, and which permits or...
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7087249 |
Treatment of mucosal membranes
The invention relates to the use of one or more antimicrobial metals preferably selected from silver, gold, platinum, and palladium but most preferably silver, formed with atomic disorder, and...
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7083808 |
Controlled/modified release oral methylphenidate formulations
The invention is directed to oral modified/controlled release methylphenidate formulations which provide a rapid initial onset of effect and a prolonged duration of effect. Preferably, the peak...
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7070803 |
Controlled release pharmaceutical composition for oral use containing midodrine and/or active metabolite, desglymidodrine
Novel controlled release pharmaceutical compositions for oral use containing midodrine and/or its active metabolite desglymidodrine. The novel compositions are designed to release midodrine and/or...
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7060293 |
Powder-layered oral dosage forms
An oral dosage form of morphine is formulated by powder-layering an homogeneous mixture of morphine sulfate and hydrous lactose impalpable onto inert beads to obtain a multiparticulate product. A...
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7060263 |
Super absorption Coenzyme Q10
An improved soft gelatin formulation and process methodology that increases single Coenzyme Q 10 molecules presented to the absorption channels of the small intestines by providing medium chain...
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7048945 |
Timed pulsatile drug delivery systems
A pharmaceutical dosage form such as a capsule capable of delivering therapeutic agents into the body in a time-controlled or position-controlled pulsatile release fashion, is composed of a...
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7030162 |
Treatment of migraine headache
The invention is directed to pharmaceutical compositions useful in the treatment of migraine. The compositions contain metoclopramide and one or more NSAIDs in unit dosage form. By selecting NSAIDs...
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7022350 |
Dietary supplement
A dietary supplement for treating or preventing prostate disease and/or vascular disease including saw palmetto, d-alpha tocopherol, d-gamma tocopherol, d-delta tocopherol, d-beta tocopherol,...
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7019106 |
Lactic acid polymer and process for producing the same
A process for producing a lactic acid polymer of 15,000 to 50,000 in weight-average molecular weight, the content of polymeric materials having not more than about 5,000 in weight-average molecular...
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7014859 |
Entomopathogenic nematode for control of insect pests
A nematode collected from Diaprepes abbreviatus was identified and described as a new species, Steinernema diaprepesi n. sp. The new species can be distinguished from other species of the genus...
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RE39030 |
Fluoxetine enteric pellets and methods for their preparation and use
A superior enteric formulation of the antidepressant drug, fluoxetine, is in the form of enteric pellets of which the enteric layer comprises hydroxypropylmethylcellulose acetate succinate.
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7011847 |
Enteric coated formulation for bisphosphonic acids and salts thereof
Pharmaceutical compositions and methods of using the composition are provided. The pharmaceutical composition comprises an inert core surrounded by an active coating containing one or more...
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7008640 |
Pharmaceutical composition for oral use with improved absorption
The present invention presents a pharmaceutical composition for oral use with improved absorption, which comprises drug, aminoalkyl methacrylate copolymer E, and acidic substance and is obtained by...
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6994873 |
Multiparticulate formulations of lithium salts for oral administration suitable for once-a-day administration
This invention refers to:
multiparticulate formulations of Lithium salts for oral administration constituted by either modified release granules or mixtures of modified and conventional...
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6991807 |
Antibiotic composition
Disclosed are antibiotic products for delivering at least two different antibiotics, wherein the products are comprised of at least three or four dosage forms with different release profiles and...
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6989159 |
Pharmaceutical compositions containing lithium carbonate
Once daily pharmaceutical compositions containing lithium carbonate in the form of coated granules.
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6979468 |
Oral composition and method for the treatment of inflammatory cutaneous disorders
A method and composition for the treatment of acne vulgaris, acne rosacea, and other inflammatory skin conditions comprises the oral administration of a composition comprising a dose of...
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6962717 |
Pharmaceutical compositions
A pharmaceutical composition for slow release of active ingredient in the gastrointestinal tract, comprising a plurality of active ingredient-containing particles coated with a material insoluble...
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