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6172250 |
Preparation process of biologically active silicon compounds in a concentrated form
A process for the preparation of biologically active silicon compounds by hydrolysis of a precursor which produces a compound which prevents the formation of polymers from the silicon hydrolyzed...
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6165503 |
High strength capsules, process of preparing and using the same
In the formation of capsules having a polyanionic polysaccharide core and a polycationic polysaccharide membrane layer, improved binding of the polycationic polysaccharide is achieved by including...
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6162467 |
Sustained release compositions and a method of preparing pharmaceutical compositions
A process for the manufacture of particles comprises mechanically working a mixture of a drug and a hydrophobic and/or hydrophilic fusible carrier in a high speed mixture so as to form...
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6162463 |
Extended release formulation of diltiazem hydrochloride
An extended release formulation of diltiazem which is suitable for once-daily oral administration comprises a quantity of a quick release preparation of diltiazem or a pharmaceutically active salt...
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6159501 |
Modified release multiple-units dosage composition for release of opioid compounds
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6159499 |
Composition containing an acid-labile benzimidazole and process for its preparation
The present invention relates to a composition, particularly adapted to oral administration, substantially free of alkaline-reacting compounds. The composition comprises (a) a core containing an...
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6143328 |
Sustained release compositions and a method of preparing pharmaceutical compositions
Sustained release pharmaceutical formulations containing morphine, or a pharmaceutically acceptable salt thereof, as active ingredient, suitable for administration on a once daily basis, are...
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6136327 |
Stereospecific delivery of a drug using electrotransport
Preferential delivery via electrotransport of a preferred isomeric form of a pharmaceutically active chiral compound from a mixture of the isomeric forms of said compound is provided. A method of...
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6117450 |
Method of making a perorally administered solid drug with controlled effective ingredient delivery
The method of making a solid drug with controlled effective ingredient delivery for oral administration includes selecting a predetermined number of at least three of four compressed compositions...
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6113935 |
Water-in-oil microencapsulation process and microcapsules produced thereby
A suspension of microcapsules in an organic liquid, the microcapsules containing an aqueous phase, is produced by interfacial polymerization in the presence of a proton transfer catalyst of a...
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6110494 |
Cisapride mini-tablet formulations
A sustained release cisapride oral dosage formulation suitable for once-daily administration comprises a plurality of mini-tablets containing cisapride or a salt thereof with an organic acid and...
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6103264 |
Process for preparing a controlled release composition
A process for preparing a controlled release composition with a controlled release matrix and containing a pharmaceutically active ingredient, which comprises granulating the active ingredient with...
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6086918 |
Oral peptide pharmaceutical products
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6086633 |
Method for preserving animal hides
Compositions and methods for preserving untanned animal hides, wherein the compositions comprise 50-95% (w/w) of a polyether antibiotic and 5-25% (w/w) of a surface-acting agent. In these...
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6083514 |
Polymethylpentene container for an inhalation anesthetic
A pharmaceutical product. The pharmaceutical product includes a container constructed from a material containing polymethylpentene. The container defines an interior space. A volume of a...
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6077537 |
Non-sedating acrivastine product
The present invention relates to methods of using and compositions containing acrivastine which provide antihistaminic therapeutic benefits while minimizing undesirable central nervous system side...
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6077532 |
Pharmaceutical ion exchange resin composition
A process is provided for preparing a granular pharmnaceutical ion exchange resin composition that is readily dispersible in water by granulating an ion exchange resin, having a pharmacologically...
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6077531 |
Estradiol and progesterone-based medicament
A medicament consisting of a biological medium-soluble capsule containing a micronised progesterone suspended in oil is disclosed, characterised in that the capsule also contains estradiol enclosed...
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6068855 |
Pharmaceutical composition containing a fusible carrier and method for producing the same
A process for the manufacture of particles comprises mechanically working a mixture of a drug and a hydrophobic and/or hydrophilic fusible carrier in a high speed mixture so as to form...
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6068981 |
Marking of orally ingested products
A method of monitoring a therapeutic regimen in an animal, the method involving a) providing to the animal a therapeutic compound and a detectable compound that passes into the bloodstream,...
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6036973 |
Therapy for neurological diseases
A dosage form is disclosed for administering 10 ng to 1200 mg tacrine to a patient in need of tacrine therapy.
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6030642 |
Extended release clonidine formulation (capsule)
A method of providing a patient needing clonidine with an extended dosage of clonidine over a prolonged period of time. Such method involves administering to the patient an oral dosage unit...
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6030641 |
Sustained release capsule and method for preparing the same
A sustained release capsule in which an outer surface of a hard capsule mainly composed of gelatin and containing a physiologically active substance is uniformly covered with a film material...
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6027748 |
Pharmaceutical tablet, completely coated, for controlled release of active principles that present problems of bio-availability linked to gastro-intestinal absorption
Described herein is a particular type of pharmaceutical tablet, for oral use, which is formed by one or more layers, and is specifically designed for controlled release of active principles that...
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6025391 |
Enteric-coated pharmaceutical compositions of mycophenolate
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6015577 |
Pharmaceutical compositions containing dipyridamole or mopidamol and acetylsalicylic acid or the physiologically acceptable salts thereof, processes for preparing them and their use in treating clot formation
The specification describes a pharmaceutical combination consisting of dipyridamole or mopidamol and acetylsalicylic acid or the physiologically acceptable salts thereof, processes for preparing...
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5993855 |
Delayed drug-releasing microspheres
Microspheres prepared by emulsifying an aqueous phase containing a drug and an oil phase containing a biodegradable polymer to form a W/O emulsion, and then mixing and agitating this emulsion with...
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5976577 |
Process for preparing fast dispersing solid oral dosage form
Process is provided for preparing an oral solid rapidly disintegrating freeze-dried dosage form of a pharmaceutically active substance having an unacceptable taste, wherein prior to freeze drying,...
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5977175 |
Methods and compositions for improving digestion and absorption in the small intestine
The present invention provides methods and compositions for slowing gastrointestinal transit and prolonging residence time to optimize presentation and absorption of ingested nutrients and/or...
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5968550 |
Liquisolid systems and methods of preparing same
Liquisolid systems are acceptably flowing and compressible powdered forms of liquid medications. According to the concept of liquisolid systems, liquid lipophilic drugs, or water-insoluble solid...
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5965163 |
Substained release compositions and a method of preparing pharmaceutical compositions
A process for the manufacture of particles comprises mechanically working a mixture of a drug and a hydrophobic and/or hydrophilic fusible carrier in a high speed mixture so as to form...
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5965161 |
Extruded multi-particulates
A unit dose sustained-release oral dosage form containing a plurality of melt-extruded particles, each consisting essentially of a therapeutically active agent, one or more retardants, and an...
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5958452 |
Extruded orally administrable opioid formulations
Bioavailable sustained release oral opioid analgesic dosage forms, comprising a plurality of multiparticulates produced via melt extrusion techniques are disclosed.
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5958451 |
Process for producing porous, controlled-release capsules and encapsulated composition
The porous capslues were prepared by mechanical drilling, addition of effervescent to gelatin solution, or purging of inert gas into the gelatin solution. The porous capsules were then hardened by...
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5958456 |
Controlled release formulation (albuterol)
A sustained release pharmaceutical formulation and methods of making and using the same are provided. The sustained release pharmaceutical formulation includes a sustained release excipient...
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5955104 |
Multiple unit oral pharmaceutical formulations
A multiple unit oral pharmaceutical dosage form having a plurality of pellets in a water soluble capsule or in a tablet compressed from the pellets, wherein each pellet contains (a) a substantially...
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5955103 |
Dosage form comprising antiepileptic drug
A dosage form is disclosed for delivering an antiepileptic drug, which dosage form comprises a laminated wall for maintaining the integrity of the dosage form and of the antiepileptic drug.
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5952294 |
Peptidyl prodrugs and methods of making and using the same
Peptidyl prodrugs of therapeutic agents having an activating function are sclosed. These therapeutic agents having activating functions include those having an amino, thiol, or hydroxyl function....
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5952005 |
Controlled release preparation for administering morphine
An oral pharmaceutical preparation containing a therapeutically effective amount of a salt of morphine for administration once daily is provided. The preparation contains particles which have a...
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5942248 |
Pharmaceutical composition containing a low detergent effect bile salt and an active compound that undergoes biliary excretion and/or enterohepatic recycling
Non-steroidal anti-inflammatory drugs, such as indomethacin, and other pharmaceutically active compounds, are formulated with bile acids or their salts and conjugates. Bile acids previously...
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5932246 |
Therapeutic uses of verapamil enantiomers
Substantially single enantiomer (R or S) verapamil, or a pharmaceutically-acceptable salt thereof provides an improved treatment for patients having a condition susceptible to treatment with...
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5932245 |
Gelatin or collagen hydrolysate containing drug formulation that provides for immediate release of nanoparticle drug compounds
Nanosols and process for preparing the same allow colloidally dispersed solutions of scarcely water-soluble active substances to be stabilized with gelatin or its derivatives, by partly or fully...
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5929053 |
Pesticidal composition and method for controlling pests using the same
A pesticidal composition comprising microcapsules, each microencapsulating an organophosphorus compound having a melting point of at least 15° C., a proportion (A) of aromatic ring structure in...
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5914134 |
Process for the pulsatile delivery of diltiazem HCL and product produced thereby
A drug delivery system for diltiazem-HCl comprises: a blend of fast, medium and slow release fractions of a multi-layered diltiazem bead substrate, the fast release fraction comprised of a...
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5912014 |
Oral salmon calcitonin pharmaceutical products
Bioavailability of salmon calcitonin to be administered orally is enhanced by a pharmaceutical composition providing targeted release of the peptide to the intestine, together with an absorption...
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5902565 |
Spray dried vaccine preparation comprising aluminium adsorbed immunogens
Vaccine preparations in stable particulate form are disclosed. An immediate-release preparation comprises an immunogen adsorbed to an aluminum adjuvant. A controlled- or delayed-release preparation...
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5900431 |
Use of fumagillol and derivatives thereof for preparing medicaments against intestinal infections
The invention relates to the use of fumagillol and the esters formed by fumagillol and saturated or unsaturated (C 1 -C 12 ) alkylcarboxylic or (C 1 -C 12 ) alkyldicarboxylic acids, and their...
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5900425 |
Pharmaceutical preparations having controlled release of active compound and processes for their preparation
The invention relates to pharmaceutical preparations having controlled release of active compound and to processes for their preparation, in particular for poorly soluble active compounds having...
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5900252 |
Method for targeted and controlled release of drugs in the intestinal tract and more particularly in the colon
The object of the present invention is to obtain a targeted and controlled release of drugs, the pharmacological action and absorption of which takes place in the intestine and in particular in the...
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5891470 |
Softgel formulation containing retinol
A softgel formulation containing retinol comprises a soft gelatin shell and a fill material within that shell containing retinol-impregnated microparticles. The fill material may be an optionally...
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