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6172250 Preparation process of biologically active silicon compounds in a concentrated form  
A process for the preparation of biologically active silicon compounds by hydrolysis of a precursor which produces a compound which prevents the formation of polymers from the silicon hydrolyzed...
6165503 High strength capsules, process of preparing and using the same  
In the formation of capsules having a polyanionic polysaccharide core and a polycationic polysaccharide membrane layer, improved binding of the polycationic polysaccharide is achieved by including...
6162467 Sustained release compositions and a method of preparing pharmaceutical compositions  
A process for the manufacture of particles comprises mechanically working a mixture of a drug and a hydrophobic and/or hydrophilic fusible carrier in a high speed mixture so as to form...
6162463 Extended release formulation of diltiazem hydrochloride  
An extended release formulation of diltiazem which is suitable for once-daily oral administration comprises a quantity of a quick release preparation of diltiazem or a pharmaceutically active salt...
6159501 Modified release multiple-units dosage composition for release of opioid compounds  
6159499 Composition containing an acid-labile benzimidazole and process for its preparation  
The present invention relates to a composition, particularly adapted to oral administration, substantially free of alkaline-reacting compounds. The composition comprises (a) a core containing an...
6143328 Sustained release compositions and a method of preparing pharmaceutical compositions  
Sustained release pharmaceutical formulations containing morphine, or a pharmaceutically acceptable salt thereof, as active ingredient, suitable for administration on a once daily basis, are...
6136327 Stereospecific delivery of a drug using electrotransport  
Preferential delivery via electrotransport of a preferred isomeric form of a pharmaceutically active chiral compound from a mixture of the isomeric forms of said compound is provided. A method of...
6117450 Method of making a perorally administered solid drug with controlled effective ingredient delivery  
The method of making a solid drug with controlled effective ingredient delivery for oral administration includes selecting a predetermined number of at least three of four compressed compositions...
6113935 Water-in-oil microencapsulation process and microcapsules produced thereby  
A suspension of microcapsules in an organic liquid, the microcapsules containing an aqueous phase, is produced by interfacial polymerization in the presence of a proton transfer catalyst of a...
6110494 Cisapride mini-tablet formulations  
A sustained release cisapride oral dosage formulation suitable for once-daily administration comprises a plurality of mini-tablets containing cisapride or a salt thereof with an organic acid and...
6103264 Process for preparing a controlled release composition  
A process for preparing a controlled release composition with a controlled release matrix and containing a pharmaceutically active ingredient, which comprises granulating the active ingredient with...
6086918 Oral peptide pharmaceutical products  
6086633 Method for preserving animal hides  
Compositions and methods for preserving untanned animal hides, wherein the compositions comprise 50-95% (w/w) of a polyether antibiotic and 5-25% (w/w) of a surface-acting agent. In these...
6083514 Polymethylpentene container for an inhalation anesthetic  
A pharmaceutical product. The pharmaceutical product includes a container constructed from a material containing polymethylpentene. The container defines an interior space. A volume of a...
6077537 Non-sedating acrivastine product  
The present invention relates to methods of using and compositions containing acrivastine which provide antihistaminic therapeutic benefits while minimizing undesirable central nervous system side...
6077532 Pharmaceutical ion exchange resin composition  
A process is provided for preparing a granular pharmnaceutical ion exchange resin composition that is readily dispersible in water by granulating an ion exchange resin, having a pharmacologically...
6077531 Estradiol and progesterone-based medicament  
A medicament consisting of a biological medium-soluble capsule containing a micronised progesterone suspended in oil is disclosed, characterised in that the capsule also contains estradiol enclosed...
6068855 Pharmaceutical composition containing a fusible carrier and method for producing the same  
A process for the manufacture of particles comprises mechanically working a mixture of a drug and a hydrophobic and/or hydrophilic fusible carrier in a high speed mixture so as to form...
6068981 Marking of orally ingested products  
A method of monitoring a therapeutic regimen in an animal, the method involving a) providing to the animal a therapeutic compound and a detectable compound that passes into the bloodstream,...
6036973 Therapy for neurological diseases  
A dosage form is disclosed for administering 10 ng to 1200 mg tacrine to a patient in need of tacrine therapy.
6030642 Extended release clonidine formulation (capsule)  
A method of providing a patient needing clonidine with an extended dosage of clonidine over a prolonged period of time. Such method involves administering to the patient an oral dosage unit...
6030641 Sustained release capsule and method for preparing the same  
A sustained release capsule in which an outer surface of a hard capsule mainly composed of gelatin and containing a physiologically active substance is uniformly covered with a film material...
6027748 Pharmaceutical tablet, completely coated, for controlled release of active principles that present problems of bio-availability linked to gastro-intestinal absorption  
Described herein is a particular type of pharmaceutical tablet, for oral use, which is formed by one or more layers, and is specifically designed for controlled release of active principles that...
6025391 Enteric-coated pharmaceutical compositions of mycophenolate  
6015577 Pharmaceutical compositions containing dipyridamole or mopidamol and acetylsalicylic acid or the physiologically acceptable salts thereof, processes for preparing them and their use in treating clot formation  
The specification describes a pharmaceutical combination consisting of dipyridamole or mopidamol and acetylsalicylic acid or the physiologically acceptable salts thereof, processes for preparing...
5993855 Delayed drug-releasing microspheres  
Microspheres prepared by emulsifying an aqueous phase containing a drug and an oil phase containing a biodegradable polymer to form a W/O emulsion, and then mixing and agitating this emulsion with...
5976577 Process for preparing fast dispersing solid oral dosage form  
Process is provided for preparing an oral solid rapidly disintegrating freeze-dried dosage form of a pharmaceutically active substance having an unacceptable taste, wherein prior to freeze drying,...
5977175 Methods and compositions for improving digestion and absorption in the small intestine  
The present invention provides methods and compositions for slowing gastrointestinal transit and prolonging residence time to optimize presentation and absorption of ingested nutrients and/or...
5968550 Liquisolid systems and methods of preparing same  
Liquisolid systems are acceptably flowing and compressible powdered forms of liquid medications. According to the concept of liquisolid systems, liquid lipophilic drugs, or water-insoluble solid...
5965163 Substained release compositions and a method of preparing pharmaceutical compositions  
A process for the manufacture of particles comprises mechanically working a mixture of a drug and a hydrophobic and/or hydrophilic fusible carrier in a high speed mixture so as to form...
5965161 Extruded multi-particulates  
A unit dose sustained-release oral dosage form containing a plurality of melt-extruded particles, each consisting essentially of a therapeutically active agent, one or more retardants, and an...
5958452 Extruded orally administrable opioid formulations  
Bioavailable sustained release oral opioid analgesic dosage forms, comprising a plurality of multiparticulates produced via melt extrusion techniques are disclosed.
5958451 Process for producing porous, controlled-release capsules and encapsulated composition  
The porous capslues were prepared by mechanical drilling, addition of effervescent to gelatin solution, or purging of inert gas into the gelatin solution. The porous capsules were then hardened by...
5958456 Controlled release formulation (albuterol)  
A sustained release pharmaceutical formulation and methods of making and using the same are provided. The sustained release pharmaceutical formulation includes a sustained release excipient...
5955104 Multiple unit oral pharmaceutical formulations  
A multiple unit oral pharmaceutical dosage form having a plurality of pellets in a water soluble capsule or in a tablet compressed from the pellets, wherein each pellet contains (a) a substantially...
5955103 Dosage form comprising antiepileptic drug  
A dosage form is disclosed for delivering an antiepileptic drug, which dosage form comprises a laminated wall for maintaining the integrity of the dosage form and of the antiepileptic drug.
5952294 Peptidyl prodrugs and methods of making and using the same  
Peptidyl prodrugs of therapeutic agents having an activating function are sclosed. These therapeutic agents having activating functions include those having an amino, thiol, or hydroxyl function....
5952005 Controlled release preparation for administering morphine  
An oral pharmaceutical preparation containing a therapeutically effective amount of a salt of morphine for administration once daily is provided. The preparation contains particles which have a...
5942248 Pharmaceutical composition containing a low detergent effect bile salt and an active compound that undergoes biliary excretion and/or enterohepatic recycling  
Non-steroidal anti-inflammatory drugs, such as indomethacin, and other pharmaceutically active compounds, are formulated with bile acids or their salts and conjugates. Bile acids previously...
5932246 Therapeutic uses of verapamil enantiomers  
Substantially single enantiomer (R or S) verapamil, or a pharmaceutically-acceptable salt thereof provides an improved treatment for patients having a condition susceptible to treatment with...
5932245 Gelatin or collagen hydrolysate containing drug formulation that provides for immediate release of nanoparticle drug compounds  
Nanosols and process for preparing the same allow colloidally dispersed solutions of scarcely water-soluble active substances to be stabilized with gelatin or its derivatives, by partly or fully...
5929053 Pesticidal composition and method for controlling pests using the same  
A pesticidal composition comprising microcapsules, each microencapsulating an organophosphorus compound having a melting point of at least 15° C., a proportion (A) of aromatic ring structure in...
5914134 Process for the pulsatile delivery of diltiazem HCL and product produced thereby  
A drug delivery system for diltiazem-HCl comprises: a blend of fast, medium and slow release fractions of a multi-layered diltiazem bead substrate, the fast release fraction comprised of a...
5912014 Oral salmon calcitonin pharmaceutical products  
Bioavailability of salmon calcitonin to be administered orally is enhanced by a pharmaceutical composition providing targeted release of the peptide to the intestine, together with an absorption...
5902565 Spray dried vaccine preparation comprising aluminium adsorbed immunogens  
Vaccine preparations in stable particulate form are disclosed. An immediate-release preparation comprises an immunogen adsorbed to an aluminum adjuvant. A controlled- or delayed-release preparation...
5900431 Use of fumagillol and derivatives thereof for preparing medicaments against intestinal infections  
The invention relates to the use of fumagillol and the esters formed by fumagillol and saturated or unsaturated (C 1 -C 12 ) alkylcarboxylic or (C 1 -C 12 ) alkyldicarboxylic acids, and their...
5900425 Pharmaceutical preparations having controlled release of active compound and processes for their preparation  
The invention relates to pharmaceutical preparations having controlled release of active compound and to processes for their preparation, in particular for poorly soluble active compounds having...
5900252 Method for targeted and controlled release of drugs in the intestinal tract and more particularly in the colon  
The object of the present invention is to obtain a targeted and controlled release of drugs, the pharmacological action and absorption of which takes place in the intestine and in particular in the...
5891470 Softgel formulation containing retinol  
A softgel formulation containing retinol comprises a soft gelatin shell and a fill material within that shell containing retinol-impregnated microparticles. The fill material may be an optionally...