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6599511 |
Pharmaceutical composition containing desoxypeganine for the treatment of drug dependence
Desoxypeganine and its pharmaceutically acceptable acid addition salts can be used in the treatment of drug addiction or drug dependence. Said substances are administered preferably in a continuos...
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6599529 |
Modified release multiple-units compositions of non-steroid anti-inflammatory drug substances (NSAIDs)
An oral pharmaceutical modified release multiple-units composition for the administration of a therapeutically and/or prophylactically effective amount of a non-steroid anti-inflammatory drug...
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6596310 |
Method of artificial insemination by timed release of sperm from capsules or solid beads
A method is provided for encapsulating sperm in a particle wherein the particle provides for the timed release of the sperm. In particular, the method uses a gel forming polymer to form the...
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6596308 |
Controlled release pharmaceutical composition
A sustained/prolonged release pharmaceutical dosage form is disclosed. The form comprises a hard shell capsule and a formulation comprising (a) a water insoluble medicant, (b) a high melting fatty...
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6592895 |
Biodegradable polyhydric alcohol esters
Precursor polyhydric alcohol esters where acyl moieties originate from aliphatic homopolymer or copolymer polyesters and contain free hydroxyl at their terminal ends, are reacted to provide...
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6576260 |
Sustained-release form of administration containing tramadol saccharinate
Disclosed herein is sustained-release formulations of tramadol comprising tramadol saccharinate coated with at least one sustained-release coating. The sustained release formulations may also...
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6576258 |
Pharmaceutical formulation with controlled release of active substances
There is disclosed a method for stabilizing active substances that are unstable in acidic medium, unstable when stored for longer periods of time in the presence of water and at the same time...
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6576259 |
Sustained release formulations containing tacrolimus
Sustained release formulation containing tacrolimus or its hydrate is provided. The time (T63.2%) required for 63.2% of the maximum amount of tacrolimus or its hydrate to be dissolved is 0.7 to 15...
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6572888 |
Controlled release lipoic acid
A controlled release formulation of lipoic acid is disclosed. The lipoic acid is combined with excipient materials in such a way that those materials provide for gradual release of the lipoic acid...
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6573238 |
Method for producing sustained-release formulations
Methods for preparing biodegradable microparticles are provided. Also provided are microparticles prepared by the method which include IGF-1 entrapped therein. The microparticles allow for...
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6569463 |
Solid carriers for improved delivery of hydrophobic active ingredients in pharmaceutical compositions
The present invention provides solid pharmaceutical compositions for improved delivery of a wide variety of pharmaceutical active ingredients contained therein or separately administered. In one...
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6562835 |
Method for the treatment of urinary incontinence
Urinary incontinence is alleviated in a mammal by administering to the mammal a urinary incontinence alleviating amount of dextromethorphan, dextrorphan, their mixtures and/or pharmaceutically...
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6558679 |
Container for an inhalation anesthetic
A pharmaceutical product. The pharmaceutical product includes a container constructed from a material containing one or more of polypropylene, polyethylene, and ionomeric resins. The container...
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6555136 |
Pharmaceutical dosage form for pulsatile delivery of methylphenidate
Novel pharmaceutical dosage forms provide for pulsatile delivery of methylphenidate, i.e., release encapsulated drug in spaced apart “pulses.” The dosage forms are comprised of first, second...
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6551613 |
Dosage form comprising therapeutic formulation
A dosage form is disclosed comprising a semipermeable walled container that houses a capsule, which capsule comprises a drug formulation, a piston, and an osmotic composition. The dosage form...
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6552160 |
Ester-terminated poly(ester-amides) useful for formulating transparent gels in low polarity fluids
A resin composition is prepared by reacting components comprising dibasic acid, diamine, polyol and monoalcohol, wherein (a) at least 50 equivalent percent of the dibasic acid comprises polymerized...
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6544556 |
Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and a proton pump inhibitor
An oral solid dosage form includes a therapeutically effective amount of an NSAID and a proton pump inhibitor in an amount effective to inhibit or prevent gastrointestinal side effects normally...
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6544538 |
Insecticidal composition
An insecticidal bait composition which is particularly useful against social insects, such as cockroaches and ants is disclosed. The bait composition comprises a solid or semi-solid bait matrix...
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6544553 |
Dosage forms and methods for oral delivery of progesterone
Provided is an oral dosage form suitable to deliver a combined dosage of progesterone and which upon delivery through the gastrointestinal tract provides a blood concentration of from about 0.1...
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6544555 |
Antibiotic product, use and formulation thereof
An antibiotic product is comprised of at least three dosages forms, each of which has a different release profile, with the C max for the antibiotic product being reached in less than about twelve...
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6540991 |
Stabilized active materials
A stabilized insect mating disruption pheromone compositions comprising an insect pheromone and 2,2′-Methylenebis(6-t-butyl-p-cresol). Methods of use and microcapsules containing these...
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6531160 |
Microcapsules with an aqueous core containing at least one water-soluble cosmetic or dermatological active principle and cosmetic or dermatological compositions containing them
The present invention relates to microcapsules with an aqueous core containing at least one water-soluble cosmetic or dermatological active principle, and with a polymeric and/or waxy envelope, in...
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6528539 |
Stable formulation containing fumagillin
The invention relates to a stable fumagillin formulation and to the method of use thereof in treating and/or combating intestinal infections.
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6524606 |
Bioerodible polyorthoesters containing amine groups
Bioerodible polyorthoesters useful as orthopedic implants or vehicles for the sustained delivery of pharmaceutical, cosmetic and agricultural agents contain amine functionalities and α-hydroxy...
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6521247 |
Dual iron containing nutritional supplement
The present invention relates to a nutritional supplement which comprises two different iron compounds, namely a rapidly dissolving iron compound and a slowly dissolving iron compound. The tablet...
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6517866 |
Sertraline salts and sustained-release dosage forms of sertraline
Sustained release dosage forms of sertraline which release sertraline at a rate between 1 mgA/hr and 40 mgA/hr. The dosage forms may exhibit an initial delay period during which sertraline is...
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6517871 |
Bioenhanced formulations comprising eprosartan in oral solid dosage form
This invention relates to bioenhanced formulations comprising eprosartan or eprosartan mesylate in the amorphous form, a process for its production, compositions containing the compound and methods...
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6515010 |
Carvedilol methanesulfonate
This invention relates to carvedilol methanesulfonate, compositions containing this compound and methods of using carvedilol methanesulfonate to treat hypertension, congestive heart failure and...
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6514533 |
Device for the sustained release of aggregation-stabilized, biologically active agent
A device for the sustained release in vivo of a water soluble, biologically active agent wherein the agent is susceptible to aggregation comprising a drug delivery device and...
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6514531 |
Controlled-release dosage forms comprising zolpidem or a salt thereof
The present invention relates to controlled-release dosage forms of zolpidem or salts thereof adapted to release zolpidem over a predetermined time period, according to a biphasic profile of...
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6500454 |
Timed, sustained release systems for propranolol
A unit dosage form, such as a capsule or the like for delivering drugs into the body in a circadian release fashion, is comprising of one or more populations of propranolol-containing particles...
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6491948 |
Composition comprising isoquercetin and ascorbic acid in a sustained release form
The present invention relates to novel, orally administered compositions comprising two redox systems: reduced ascorbic acid in a sustained release form and oxidized isoquercetin with an increased...
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6491952 |
Cholesterol lowering composition
The present invention concerns a composition containing a cholesterol lowering component such as β-sitosterol and/or β-sitostanol in a monomolecular, low associated or “cluster” form, where a...
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6488962 |
Tablet shapes to enhance gastric retention of swellable controlled-release oral dosage forms
The retention of oral drug dosage forms in the stomach is improved by using swellable dosage forms that are shaped in a manner that will prevent them from inadvertently passing through the pylorus...
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6475521 |
Biphasic controlled release delivery system for high solubility pharmaceuticals and method
A biphasic controlled release delivery system for pharmaceuticals which have high water solubility, such as the antidiabetic metformin HCl salt, is provided which provides a dosage form that has...
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6468559 |
Enteric coated formulation of bishosphonic acid compounds and associated therapeutic methods
Oral dosage forms are provided for the administration of a bisphosphonic acid compound in the prevention and treatment of conditions involving calcium or phosphate metabolism, i.e., conditions...
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6444221 |
Methods of treating chronic inflammatory diseases using carbonyl trapping agents
These and other objects of this invention are achieved by providing a novel method and compositions for the clinical treatment of chronic inflammatory diseases. This invention involves use of...
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6440457 |
Method of administering antidepressant dosage form
The invention pertains to a dosage form 10 and to administering an antidepressant medicament 16 for an extended period of time in a rate-known dose.
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6436438 |
Tramadol multiple unit formulations
A multiple unit oral pharmaceutical dosage form having a plurality of pellets in a water soluble capsule or in a tablet compressed from the pellets, wherein each pellet contains (a) a substantially...
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6428529 |
Epidural administration of therapeutic compounds with sustained rate of release
A drug delivery system provides sustained-release delivery of therapeutic biologically active compounds administered epidurally. In the preferred embodiment the biologically active compound is an...
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6426089 |
Multilayered soft capsule for eliminating bad breath and process for producing the same
The present invention provides a multi-layered soft capsule for effectively eliminating bad breath, and a method for producing the same. The multi-layered soft capsule ( 10 ) for eliminating bad...
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6426088 |
Encapsulated cells producing antibodies
The present invention relates to capsules encapsulating antibody-producing cells, and to use of such capsules and encapsulated cells, respectively, for implantation in vivo for long term delivery...
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6423340 |
Method for the treatment of inflammatory bowel diseases
Described herein are methods comprising the oral administration of budesonide for the treatment of ulcerative colitis and Crohn's colitis in its active phase. The methods can also be applied as...
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6419951 |
Sustained releasing drug comprising copolymers and process for preparing the same
A sustained releasing drug which includes an effective component and a copolymer having a weight-average molecular weight of 1,000 to 100,000 which comprises, as repeating structure units, both of...
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6419954 |
Tablets and methods for modified release of hydrophilic and other active agents
The invention provides a tablet and methods for making the tablet comprising a gel-forming material and at least one particle comprising an active agent in contact with a coating material to modify...
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6416781 |
Device for releasing with delayed effect an active substance, in particular veterinary
A device for dispensing an active substance to be used in a biological medium, in particular in the rumen of an animal, includes a sealed receptacle for containing the substance, and having at...
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6413539 |
Hydrogel-forming, self-solvating absorbable polyester copolymers, and methods for use thereof
The present invention provides novel hydrogel-forming, self-solvating, absorbable polyester copolymers capable of selective, segmental association into compliant hydrogels upon contacting an...
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6407057 |
Ovulation triggering drugs
The invention relates to medicaments for initiating ovulation comprising LH in an administrable form which ensures an increase in LH plasma levels for a period of some 40 to 60 hours.
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6406703 |
Treatment of H. pylori associated gastroduodenal disease
The application discloses a method for the treatment of Heliobacter infection in a mammalian host, which comprises administration to said infected host of an immunologically effective amount of one...
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6406716 |
Anticonvulsant containing composition for treating neuropathic pain
The effectiveness of an anticonvulsant such as gabapentin for alleviating neuropathic pain is potentiated by a nontoxic antagonist for the N-methyl-D-aspartate receptor or nontoxic substance that...
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