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6599511 Pharmaceutical composition containing desoxypeganine for the treatment of drug dependence  
Desoxypeganine and its pharmaceutically acceptable acid addition salts can be used in the treatment of drug addiction or drug dependence. Said substances are administered preferably in a continuos...
6599529 Modified release multiple-units compositions of non-steroid anti-inflammatory drug substances (NSAIDs)  
An oral pharmaceutical modified release multiple-units composition for the administration of a therapeutically and/or prophylactically effective amount of a non-steroid anti-inflammatory drug...
6596310 Method of artificial insemination by timed release of sperm from capsules or solid beads  
A method is provided for encapsulating sperm in a particle wherein the particle provides for the timed release of the sperm. In particular, the method uses a gel forming polymer to form the...
6596308 Controlled release pharmaceutical composition  
A sustained/prolonged release pharmaceutical dosage form is disclosed. The form comprises a hard shell capsule and a formulation comprising (a) a water insoluble medicant, (b) a high melting fatty...
6592895 Biodegradable polyhydric alcohol esters  
Precursor polyhydric alcohol esters where acyl moieties originate from aliphatic homopolymer or copolymer polyesters and contain free hydroxyl at their terminal ends, are reacted to provide...
6576260 Sustained-release form of administration containing tramadol saccharinate  
Disclosed herein is sustained-release formulations of tramadol comprising tramadol saccharinate coated with at least one sustained-release coating. The sustained release formulations may also...
6576258 Pharmaceutical formulation with controlled release of active substances  
There is disclosed a method for stabilizing active substances that are unstable in acidic medium, unstable when stored for longer periods of time in the presence of water and at the same time...
6576259 Sustained release formulations containing tacrolimus  
Sustained release formulation containing tacrolimus or its hydrate is provided. The time (T63.2%) required for 63.2% of the maximum amount of tacrolimus or its hydrate to be dissolved is 0.7 to 15...
6572888 Controlled release lipoic acid  
A controlled release formulation of lipoic acid is disclosed. The lipoic acid is combined with excipient materials in such a way that those materials provide for gradual release of the lipoic acid...
6573238 Method for producing sustained-release formulations  
Methods for preparing biodegradable microparticles are provided. Also provided are microparticles prepared by the method which include IGF-1 entrapped therein. The microparticles allow for...
6569463 Solid carriers for improved delivery of hydrophobic active ingredients in pharmaceutical compositions  
The present invention provides solid pharmaceutical compositions for improved delivery of a wide variety of pharmaceutical active ingredients contained therein or separately administered. In one...
6562835 Method for the treatment of urinary incontinence  
Urinary incontinence is alleviated in a mammal by administering to the mammal a urinary incontinence alleviating amount of dextromethorphan, dextrorphan, their mixtures and/or pharmaceutically...
6558679 Container for an inhalation anesthetic  
A pharmaceutical product. The pharmaceutical product includes a container constructed from a material containing one or more of polypropylene, polyethylene, and ionomeric resins. The container...
6555136 Pharmaceutical dosage form for pulsatile delivery of methylphenidate  
Novel pharmaceutical dosage forms provide for pulsatile delivery of methylphenidate, i.e., release encapsulated drug in spaced apart “pulses.” The dosage forms are comprised of first, second...
6551613 Dosage form comprising therapeutic formulation  
A dosage form is disclosed comprising a semipermeable walled container that houses a capsule, which capsule comprises a drug formulation, a piston, and an osmotic composition. The dosage form...
6552160 Ester-terminated poly(ester-amides) useful for formulating transparent gels in low polarity fluids  
A resin composition is prepared by reacting components comprising dibasic acid, diamine, polyol and monoalcohol, wherein (a) at least 50 equivalent percent of the dibasic acid comprises polymerized...
6544556 Pharmaceutical formulations containing a non-steroidal antiinflammatory drug and a proton pump inhibitor  
An oral solid dosage form includes a therapeutically effective amount of an NSAID and a proton pump inhibitor in an amount effective to inhibit or prevent gastrointestinal side effects normally...
6544538 Insecticidal composition  
An insecticidal bait composition which is particularly useful against social insects, such as cockroaches and ants is disclosed. The bait composition comprises a solid or semi-solid bait matrix...
6544553 Dosage forms and methods for oral delivery of progesterone  
Provided is an oral dosage form suitable to deliver a combined dosage of progesterone and which upon delivery through the gastrointestinal tract provides a blood concentration of from about 0.1...
6544555 Antibiotic product, use and formulation thereof  
An antibiotic product is comprised of at least three dosages forms, each of which has a different release profile, with the C max for the antibiotic product being reached in less than about twelve...
6540991 Stabilized active materials  
A stabilized insect mating disruption pheromone compositions comprising an insect pheromone and 2,2′-Methylenebis(6-t-butyl-p-cresol). Methods of use and microcapsules containing these...
6531160 Microcapsules with an aqueous core containing at least one water-soluble cosmetic or dermatological active principle and cosmetic or dermatological compositions containing them  
The present invention relates to microcapsules with an aqueous core containing at least one water-soluble cosmetic or dermatological active principle, and with a polymeric and/or waxy envelope, in...
6528539 Stable formulation containing fumagillin  
The invention relates to a stable fumagillin formulation and to the method of use thereof in treating and/or combating intestinal infections.
6524606 Bioerodible polyorthoesters containing amine groups  
Bioerodible polyorthoesters useful as orthopedic implants or vehicles for the sustained delivery of pharmaceutical, cosmetic and agricultural agents contain amine functionalities and α-hydroxy...
6521247 Dual iron containing nutritional supplement  
The present invention relates to a nutritional supplement which comprises two different iron compounds, namely a rapidly dissolving iron compound and a slowly dissolving iron compound. The tablet...
6517866 Sertraline salts and sustained-release dosage forms of sertraline  
Sustained release dosage forms of sertraline which release sertraline at a rate between 1 mgA/hr and 40 mgA/hr. The dosage forms may exhibit an initial delay period during which sertraline is...
6517871 Bioenhanced formulations comprising eprosartan in oral solid dosage form  
This invention relates to bioenhanced formulations comprising eprosartan or eprosartan mesylate in the amorphous form, a process for its production, compositions containing the compound and methods...
6515010 Carvedilol methanesulfonate  
This invention relates to carvedilol methanesulfonate, compositions containing this compound and methods of using carvedilol methanesulfonate to treat hypertension, congestive heart failure and...
6514533 Device for the sustained release of aggregation-stabilized, biologically active agent  
A device for the sustained release in vivo of a water soluble, biologically active agent wherein the agent is susceptible to aggregation comprising a drug delivery device and...
6514531 Controlled-release dosage forms comprising zolpidem or a salt thereof  
The present invention relates to controlled-release dosage forms of zolpidem or salts thereof adapted to release zolpidem over a predetermined time period, according to a biphasic profile of...
6500454 Timed, sustained release systems for propranolol  
A unit dosage form, such as a capsule or the like for delivering drugs into the body in a circadian release fashion, is comprising of one or more populations of propranolol-containing particles...
6491948 Composition comprising isoquercetin and ascorbic acid in a sustained release form  
The present invention relates to novel, orally administered compositions comprising two redox systems: reduced ascorbic acid in a sustained release form and oxidized isoquercetin with an increased...
6491952 Cholesterol lowering composition  
The present invention concerns a composition containing a cholesterol lowering component such as β-sitosterol and/or β-sitostanol in a monomolecular, low associated or “cluster” form, where a...
6488962 Tablet shapes to enhance gastric retention of swellable controlled-release oral dosage forms  
The retention of oral drug dosage forms in the stomach is improved by using swellable dosage forms that are shaped in a manner that will prevent them from inadvertently passing through the pylorus...
6475521 Biphasic controlled release delivery system for high solubility pharmaceuticals and method  
A biphasic controlled release delivery system for pharmaceuticals which have high water solubility, such as the antidiabetic metformin HCl salt, is provided which provides a dosage form that has...
6468559 Enteric coated formulation of bishosphonic acid compounds and associated therapeutic methods  
Oral dosage forms are provided for the administration of a bisphosphonic acid compound in the prevention and treatment of conditions involving calcium or phosphate metabolism, i.e., conditions...
6444221 Methods of treating chronic inflammatory diseases using carbonyl trapping agents  
These and other objects of this invention are achieved by providing a novel method and compositions for the clinical treatment of chronic inflammatory diseases. This invention involves use of...
6440457 Method of administering antidepressant dosage form  
The invention pertains to a dosage form 10 and to administering an antidepressant medicament 16 for an extended period of time in a rate-known dose.
6436438 Tramadol multiple unit formulations  
A multiple unit oral pharmaceutical dosage form having a plurality of pellets in a water soluble capsule or in a tablet compressed from the pellets, wherein each pellet contains (a) a substantially...
6428529 Epidural administration of therapeutic compounds with sustained rate of release  
A drug delivery system provides sustained-release delivery of therapeutic biologically active compounds administered epidurally. In the preferred embodiment the biologically active compound is an...
6426089 Multilayered soft capsule for eliminating bad breath and process for producing the same  
The present invention provides a multi-layered soft capsule for effectively eliminating bad breath, and a method for producing the same. The multi-layered soft capsule ( 10 ) for eliminating bad...
6426088 Encapsulated cells producing antibodies  
The present invention relates to capsules encapsulating antibody-producing cells, and to use of such capsules and encapsulated cells, respectively, for implantation in vivo for long term delivery...
6423340 Method for the treatment of inflammatory bowel diseases  
Described herein are methods comprising the oral administration of budesonide for the treatment of ulcerative colitis and Crohn's colitis in its active phase. The methods can also be applied as...
6419951 Sustained releasing drug comprising copolymers and process for preparing the same  
A sustained releasing drug which includes an effective component and a copolymer having a weight-average molecular weight of 1,000 to 100,000 which comprises, as repeating structure units, both of...
6419954 Tablets and methods for modified release of hydrophilic and other active agents  
The invention provides a tablet and methods for making the tablet comprising a gel-forming material and at least one particle comprising an active agent in contact with a coating material to modify...
6416781 Device for releasing with delayed effect an active substance, in particular veterinary  
A device for dispensing an active substance to be used in a biological medium, in particular in the rumen of an animal, includes a sealed receptacle for containing the substance, and having at...
6413539 Hydrogel-forming, self-solvating absorbable polyester copolymers, and methods for use thereof  
The present invention provides novel hydrogel-forming, self-solvating, absorbable polyester copolymers capable of selective, segmental association into compliant hydrogels upon contacting an...
6407057 Ovulation triggering drugs  
The invention relates to medicaments for initiating ovulation comprising LH in an administrable form which ensures an increase in LH plasma levels for a period of some 40 to 60 hours.
6406703 Treatment of H. pylori associated gastroduodenal disease  
The application discloses a method for the treatment of Heliobacter infection in a mammalian host, which comprises administration to said infected host of an immunologically effective amount of one...
6406716 Anticonvulsant containing composition for treating neuropathic pain  
The effectiveness of an anticonvulsant such as gabapentin for alleviating neuropathic pain is potentiated by a nontoxic antagonist for the N-methyl-D-aspartate receptor or nontoxic substance that...