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6902742 |
Multiparticulate modified release composition
The invention relates to a multiparticulate modified release composition that in operation delivers an active ingredient in a pulsed or bimodal manner. The multiparticulate modified release...
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6896899 |
Pharmaceutical preparations of glutathione and methods of administration thereof
A method of increasing glutathione levels in mammalian cells comprising administering an oral bolus of encapsulated pharmaceutically stabilized glutathione in a rapidly dissolving formulation to a...
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6893658 |
Soft capsules
An object of the present invention is to provide soft capsule formulations of active vitamins D, well-suited to practical production with easy discrimination of active ingredient levels, in which...
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6890558 |
Oral pharmaceutical composition for soft capsules containing vinorelbine and method of treatment
The invention described herein relates to a pharmaceutical composition containing vinorelbine as an active ingredient which is suitable for encapsulation in soft capsules. The liquid oral...
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6878387 |
Coated medicament forms with controlled active substance release
The invention relates to a pharmaceutical preparation consisting of: (a) a core containing an active substance, optionally an excipient and common pharmaceutical additives in addition to the salt...
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6855733 |
Formulation and manufacturing process for coenzyme Q10 soft gel capsules
A soft gelatine capsule formulation for improved manufacturing of Coenzyme Q10, comprising Coenzyme Q10 in a thixatropic gelatine carrier capable of admixing without heating with Coenzyme Q10, and...
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6852309 |
Gelatin soft capsule having the properties of removal of oral smell and cleaning of oral cavity
The present invention relates to a gelatin soft capsule having the properties of removal of oral smell and cleaning of oral cavity, which contains the ingredient for masking an oral smell as an...
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6846495 |
Compositions having improved delivery of actives
The present invention pertains to compositions having improved delivery of pharmaceutical actives. These compositions comprise pharmaceutical actives in an anhydrous solvent. These compositions may...
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6841167 |
β-carboline pharmaceutical compositions
A soft capsule containing a solution or suspension of a PDE5 inhibitor, and use of the capsule in treating sexual dysfunction.
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6838091 |
Formulations comprising lipid-regulating agents
The present invention is directed to a formulation comprising a lipid-regulating agent dissolved in at least one monoglyceride as the primary solvent medium for said agent. One or more emulsifiers...
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RE38623 |
Stabilization of ascorbic acid, ascorbic acid derivatives and/or extracts containing ascorbic acid for topical use
A stable composition is provided to treat and/or prevent photo-aged skin and related skin disorders such as sunburn, wrinkles, poor skin tone and skin discoloration by topically applying to the...
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6790495 |
Method for manufacturing a shape body containing a starch, a homogenised mass containing starch and a device for manufacturing a soft capsule
The invention relates to a method for manufacturing a starch-containing shape body and a homogenised, starch-containing mass and shape bodies manufactured therefrom. The method is carried out in a...
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6787155 |
Anti-inflammatory pharmaceutical formulations
An oral pharmaceutical dosage form including a mixture of a delay release formulation of a non-steroidal anti-inflammatory drug (NSAID) and a mixture containing a prostaqlandin and one or more...
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6776999 |
Expandable gastroretentive therapeutical system with prolonged stomach retention time
The invention relates to a device for delaying the pylorus passage of orally administered medicament forms. Said device comprises a component which expands upon contact with the gastric juice and a...
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6770300 |
Rapidly decomposing chitosan-based pellets
The invention relates to porous, rapidly disintegrating, active substance-containing pellets based on chitosan or a basic chitosan derivative, manufactured according to a dripping method wherein an...
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6767555 |
Pharmaceutical compositions
This invention provides composition comprising a cyclosporin and a carrier medium.
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6767556 |
Pharmaceutical compositions comprising moexipril magnesium
Stable solid compositions comprising moxeipril magnesium can be made using moexipril or an acid addition salt thereof, by reacting the moxeipril or acid addition salt with an alkaline magnesium...
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6761903 |
Clear oil-containing pharmaceutical compositions containing a therapeutic agent
The present invention relates to pharmaceutical compositions and methods for improved solubilization of triglycerides and improved delivery of therapeutic agents. Compositions of the present...
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6759395 |
Soft-gelatin capsule comprising S-adenosylmethionine and a method for producing the same
The invention provides a novel soft gelatin capsule comprising a fill material consisting essentially of S-adenosylmethionine (SAMe) salt disposed within an enteric coated soft gelatin film.
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6753333 |
Chiral fluoroquinolone arginine salt forms
The invention relates to the new arginine salt forms of S-(−)-9-fluoro-6,7-dihydro-8-(4-hydroxypiperidin-1-yl)-5-m
ethyl-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid, a process for their...
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6753010 |
Soft gelatin capsule containing angelica oil
The present invention relates to a soft gelation capsule containing angelica essential oil which consists of capsule material and medicinal oil. Wherein the medicinal oil consists of angelica...
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6743442 |
Melt-extruded orally administrable opioid formulations
Bioavailable sustained release oral opioid analgesic dosage forms, comprising a plurality of multiparticulates produced via melt extrusion techniques are disclosed.
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6740338 |
Reduced form of Cenzyme Q in high bioavailability stable oral dosage form
The present invention relates to a reduced form of Coenzyme Q also known as ubiquinol in oral dosage form such as a gelatin capsule, preferably a soft gelatin capsule. Compositions according to the...
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6734188 |
Composition for treatment of constipation and irritable bowel syndrome
Constipation and Irritable Bowel Syndrome are treated by a delayed and sustained release composition of an opioid antagonist which commences release of the opioid antagonist in the mid to distal...
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6730319 |
Pharmaceutical compositions having depressed melting points
The present invention relates to pharmaceutical compositions that contain a solid pharmaceutically active compound having a melting point ≧37° C. and a fatty acid or a fatty acid salt or a...
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6726927 |
Preparation of enteric pharmaceutical dosage forms for omerprazole and lansoprazole
The present invention relates to new stable enteric coated pharmaceutical dosage forms for oral use containing Omeprazole or Lansoprazole, to a formulation and a method for the manufacture of such...
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6726924 |
Oral liposomal delivery system
A liposome-capsule dosage unit system for the delivery of a biologically active material is formed by encapsulating a biologically active materials in liposomes and then placing the liposome...
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6723339 |
Oil-free pharmaceutical compositions containing cyclosporin A
The present invention provides a hard gelatine capsule containing a pharmaceutical composition comprising cyclosporin A in a mixture with a surfactant of HLB value at least 10, substantially free...
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6719999 |
Formulations comprising lipid-regulating agents
The present invention is directed to a formulation comprising a lipid-regulating agent dissolved in one or more non-aqueous and/or water-miscible solvents, or optionally, in a premix of one or more...
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6720001 |
Emulsion compositions for polyfunctional active ingredients
The present invention provides pharmaceutical oil-in-water emulsions for delivery of polyfunctional active ingredients. The emulsions include an aqueous phase, an emulsifier, and an oil phase,...
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6709675 |
Thixotropic formulations for filling capsules
The invention concerns liquid or pasty thixotropic compositions containing an active substance for filling capsules at room temperature. The compositions become fluid by the effect of shearing when...
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6709669 |
Fast-dispersing dosage forms containing fish gelatin
The invention disclosed herein relates to a pharmaceutical composition comprising a carrier and an active ingredient, wherein the carrier is fish gelatin and the composition is a fast-dispersing...
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6706284 |
Bitterness-reduced oral pharmaceutical composition
The invention relates to an oral pharmaceutical composition which has excellent drug release-controlling ability in the mouth even 5 to 10 minutes after its administration and also has excellent...
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6696083 |
Vitamin/nutrient dosage regimentation
The efficacy of vitamins and other nutritional agents in treating and preventing various disease states is improved by administering therapeutically effective levels of these agents on a...
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6689382 |
Soft shell gelatin capsules containing non-steroidal anti-inflammatories
The present invention provides a pharmaceutical formulation suitable for filling softgel capsules comprising: (a) a therapeutically effective amount of a non-steroidal anti-inflammatory drug...
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6685961 |
Colored gelatin-based formulations and method
The present invention is a process for coloring gelatin-based formulations involving adding a saturated fatty acid to the gelatin-based formulation along with lake pigment, whereby the saturated...
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6676966 |
Extended release metformin hydrochloride formulations
An extended release formulation of metformin hydrochloride is disclosed. The metformin hydrochloride is encased within polymeric film layers providing for gradual release of the metformin...
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6673366 |
Breast enhancement system
A breast enhancement system for reducing the symptoms of PMS and/or non-invasive breast augmentation. The composition includes an amount of saw palmetto extract, an amount of soybean extract, an...
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6669954 |
Controlled release of drugs
A device for controlled release of pharmaceutical agents and a method for use of the device. The drug delivery device comprises a covered container with an aperture and an aperture cover,...
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6663897 |
Oral itraconazole formulations and methods of making the same
A method of manufacturing an itraconazole oral dosage form that is substantially free of residual methylene chloride comprises the steps of: (a) providing a working solution comprising an alcohol,...
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6663901 |
Pellets having a core coated with an antifungal and a polymer
The present invention is concerned with pellets comprising a 710-1180 μm (16-25 mesh) sugar core, a coating film of a water-soluble polymer and an antifungal agent, and a seal coating layer...
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6664267 |
Crystalline fluoroquinolone arginine salt form
The invention relates to the new arginine salt forms of RS-(±)-9-fluoro-6,7-dihydro-8-(4-hydroxypiperidin-1-yl)-5-m
ethyl-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid,...
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6660296 |
Sustained-release microgranules containing diltiazem as active principle
Novel forms of sustained-release microgranules (LP) containing diltiazem are disclosed. The microgranules consist of a neutral granular carrier coated with an active layer including diltiazem or a...
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6652880 |
Oral pharmaceutical compositions containing long-chain triglycerides and liphophilic surfactants
This invention is directed to pharmaceutical compositions for oral administration, wherein the drug or active ingredient is known to have stability problems associated with the use of free fatty...
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6649183 |
Methods for treating apnea and apnea disorders using optically pure R(&plus ) ondansetron
Methods for the treatment, management, or prevention of apnea and apnea disorders, or symptoms thereof, using a therapeutically effective amount of substantially optically pure R(+) ondansetron, or...
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6646014 |
Organic compounds
The present invention concerns a method for the control of various diseases in bee-hives by applying to the bee-hives an effective amount of an essential oil in a slow-release formulation whereby...
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6641837 |
Flavored vegetable starch capsule
A flavored vegetable starch capsule and the method of manufacture of the flavored capsule is provided. The capsule may comprise (a) from about 10 to about 70 parts by weight of vegetable starch;...
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6635275 |
Modified starch film compositions
The invention concerns compositions from modified starches, such as starch ethers or oxidized starch, more particularly hydroxpropylated starch (HPS) or hydroxylethylated starch (HES) for the use...
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6632671 |
Nanoparticle encapsulation system and method
The present invention generally relates to nanocapsules and methods of preparing these nanocapsules. The present invention includes a method of forming a surfactant micelle and dispersing the...
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6630150 |
Spheronized self-emulsifying system for hydrophobic and water-sensitive agents
A self-emulsifying system comprises i) microcrystalline cellulose and ii) an oily substance, surfactant, and water is useful for providing solid dosage forms of hydrophobic or water sensitive...
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