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9040080 Processing of heat-sensitive active agents  
The present disclosure relates to a method of melt processing an active agent. The method may include encapsulating an active agent in a first polymer material exhibiting a first processing...
9040081 Use of lipid containing particles comprising Quillaja saponins for the treatment of cancer  
The present invention relates to the use of lipid containing particles, such as liposomes, iscom and/or iscom matrix and posintros, comprising at least one lipid and at least one saponin for the...
9040082 Compositions and methods for treatment of chronic fatigue  
Pharmaceutical compositions and methods for the treatment of chronic fatigue in human patients comprising a central nervous system (CNS) stimulant in a daily low-dosage amount in combination with...
9034377 Opioid dosage forms having dose proportional steady state Cave and AUC and less than dose proportional single dose Cmax  
The present invention relates to a plurality of dosage forms comprising a first dosage form and second dosage form each comprising a therapeutic agent, such as an opioid; wherein the dosage...
9034410 Whole green coffee bean products and methods of production and use  
Disclosed are novel processing methods for green coffee beans that result in novel green coffee bean products, including products that incorporate whole green coffee beans. Methods include...
9034374 Acoustically sensitive drug delivery particles comprising non-lamellar forming phosphatidylethanolamine  
Novel acoustically sensitive drug carrying particles comprising non-lamellar forming lipids are disclosed, as well as uses and methods thereof. The drug carrying particles accumulate in the...
9034373 Pharmaceutical spheroids  
According to the invention glyceryl monostearate and a polymeric binder are employed as a spheronising aid in the manufacture of pharmaceutical spheroids containing no or substantially no...
9028865 Controlled release pharmaceutical compositions of pregabalin  
A controlled release pharmaceutical composition which comprises therapeutically effective amount of pregabalin or salts thereof as active ingredient, a hydrophobic release controlling agent(s) and...
9029355 Solid ganaxolone compositions and methods for the making and use thereof  
In certain embodiments, the invention is directed to composition comprising stable particles comprising ganaxolone, wherein the volume weighted median diameter (D50) of the particles is from about...
9023388 Formulation of silibinin with high efficacy and prolonged action and the preparation method thereof  
A high-efficacy, long-acting formulation of silibinin, comprising silibinin solid dispersion, silibinin-loaded silica nanoparticles, slow-release matrix material and release enhancer, wherein the...
9023630 Bone cell delivery device  
Bone cages are disclosed including devices for biocompatible implantation. The structures of bone are useful for providing living cells and tissues as well as biologically active molecules to...
9012515 Oil formulations with thickeners  
This invention is based on unexpected effect of at least one thickener to maintain suspension or dispersion of solid particles in an oil medium. Such effect of thickener enables significant higher...
9011905 Low dose topiramate/phentermine composition and methods of use thereof  
A method for effecting weight loss by administering a combination of topiramate and phentermine is provided. The phentermine is generally administered in immediate release form, in a daily dose in...
9011906 Escalating dosing regimen for effecting weight loss and treating obesity  
The present invention is drawn to novel topiramate compositions as well as methods for effecting weight loss, e.g., in the treatment of obesity and related conditions, including conditions...
9011908 Progesterone solutions for increased bioavailability  
Fill materials for hydrophobic drugs, such as progesterone, and methods of making and using thereof are described herein. The fill material contains the hydrophobic drug dissolved in one or more...
9011904 Self-breaking tablets  
Self-breaking core tablets and functionally coated tablets and capsule formulations are provided. Methods for production of these tablet and capsule formulations and their administration are also...
9005944 Bone cell delivery device  
Bone cages are disclosed including devices for biocompatible implantation. The structures of bone are useful for providing living cells and tissues as well as biologically active molecules to...
9005657 In situ mixing and application of hydrocolloid systems for pre- and post harvest use on agricultural crops  
In-situ methods of applying ethylene response manipulation formulations are disclosed. The formulations comprise at least one ethylene response manipulation agent which is at least partially...
9006267 Pharmaceutical compositions and dosage forms of thalidomide  
Pharmaceutical compositions and single unit dosage forms of thalidomide and pharmaceutically acceptable stereoisomers, prodrugs, salts, solvates, hydrates, or clathrates are disclosed. Also...
8999381 Self-emulsifying pharmaceutical compositions of rhein or diacerein  
The invention relates to self emulsifying drug delivery system based compositions of rhein or diacerein, or salts or esters or prodrugs thereof which are bioequivalent to a 50 mg diacerein...
8999360 Compositions and methods for treating extracellular parasitic infections  
There is disclosed herein a composition for treating extracellular parasitic infections, the composition comprising one or more of the following combinations: at least one quinolone or...
8992972 Capsule for sublingual and gastro-intestinal delivery of a liquid medication in a single volume limited dose  
A capsular design is disclosed for self-administered delivery of a pre-determined amount of liquid medication. The capsular design can be constructed as having either a single piece or two piece...
8992971 Non-animal soft capsule shell composition having improved disintegration and shell hardness  
The present invention relates to a non-animal soft capsule shell composition having improved disintegration stability and shell hardness. More particularly, the present invention relates to a...
8986723 Oil formulations comprising cylcopropene compounds  
A composition comprising (a) a non-aqueous pourable fluid, (b) droplets dispersed in said pourable fluid (a), wherein said droplets comprise (i) a non-aqueous continuous phase that is a solid or...
8980293 Cosmetic composition containing retinol stabilized by porous polymer beads and nanoemulsion  
The present invention relates to a method for stabilizing retinol (Vitamin A), an unstable fat-soluble material, to use the same in cosmetics. The present invention provides an anti-inflammatory...
8980870 Solid telmisartan pharmaceutical formulations  
A pharmaceutical composition comprising 3 wt. % to 50 wt. % telmisartan dispersed in a dissolving matrix comprising: (a) a basic agent in a molar ratio of basic agent:telmisartan of 1:1 to...
8980312 Seamless alginate capsules  
The present invention is directed to a dried seamless capsule comprising an alginate shell membrane encapsulating fill material, wherein: (i) the alginate shell membrane comprises a polyvalent...
8980322 Controlled release composition  
The present invention provides a controlled release composition showing release of an active ingredient (proton pump inhibitor) controlled in two or more steps at different release rates, which...
8974820 Apparatus and process for encapsulating microparticles with liquid in soft gel capsules  
The invention provides an apparatus for producing soft gel capsules having encapsulated therein microparticles, nanoparticles and fluids, said apparatus comprising: (a) two spreader boxes; (b) two...
8974819 Sustained-release chitosan capsules comprising chitosan and phytic acid  
The present invention relates to a chitosan capsule in which a soluble active ingredient is encapsulated in a matrix containing chitosan and phytic acid; a cross-linking method and materials...
8969369 Abuse-resistant controlled-release opioid dosage form  
Abuse-resistant, controlled release opioid tablets are a combination containing an opioid antagonist such as naloxone at a level above that needed to suppress the euphoric effect of the opioid, if...
8962004 Encapsulated triazinyl sulfonylurea herbicide and methods of use  
The invention relates to compositions including an encapsulated triazinyl sulfonylurea. The invention further relates to methods for controlling weeds. The invention additionally provides methods...
8962017 Formulation of silymarin with high efficacy and prolonged action and the preparation method thereof  
A high-efficacy, long-acting formulation of silymarin, comprising silymarin solid dispersion, silymarin-loaded silica nanoparticles, slow-release matrix material and release enhancer, wherein the...
8951555 Controlled release hydrocodone formulations  
A solid oral controlled-release dosage form of hydrocodone is disclosed, the dosage form comprising an analgesically effective amount of hydrocodone or a pharmaceutically acceptable salt thereof,...
8951554 Microcapsule, structure having a microcapsule, article having a microcapsule, and method of preparing microcapsules  
A microcapsule, a structure including a microcapsule, an article including a microcapsule and a method of preparing microcapsules provided, the microcapsule includes at least one material selected...
8951969 Compositions and methods for treating centrally mediated nausea and vomiting  
Provided are compositions and methods for treating or preventing nausea and vomiting in patients undergoing chemotherapy, radiotherapy, or surgery.
8945612 Capsules containing high doses of levodopa for pulmonary use  
The present invention provides a capsule containing an inhalable powder composition wherein the composition comprises about 75% by weight or more levodopa, dipalmitoylphosphatidylcholine (DPPC)...
8945611 Artificial oxygen carriers and use thereof  
The invention relates to dispersions of artificial oxygen carriers, wherein the dispersions contain capsules with reversible oxygen storage capacity, the capsules comprising an oxygen-permeable...
8927008 Compound sea cucumber product, preparation method, and dosage forms thereof  
A compound sea cucumber product, preparation method thereof and dosage forms thereof are disclosed. A fresh sea cucumber is cut open, the viscus thereof is taken out, and they are well-cleaned...
8920838 Delayed-release glucocorticoid treatment of rheumatoid disease  
Provided are methods for the treatment of a rheumatic disease, such as rheumatoid arthritis, ankylosating spondylitis and/or polymyalgia rheumatic, by administering a delayed-release dosage form...
8916192 Method and apparatus for the preparation of capsules  
An apparatus for a continuous encapsulation process is provided. The apparatus is a vibrating tubing used alone, in series, or in combination with an encapsulation apparatus, which is used alone...
8916150 Compositions and methods for enhancing metal ion dependent drug therapies  
Methods and compositions are provided for increasing responsiveness to therapeutic metalloproteases including increasing and/or maximizing responsiveness and preventing botulinum and tetanus toxin...
8906413 Drug formulations having reduced abuse potential  
Drug formulations having reduced abuse potential which contain one or more of (1) a bittering agent, (2) a bright deterrent/indicator dye and (3) fine insoluble particulate matter. The bittering...
8895058 Low dose topiramate/phentermine composition and methods of use thereof  
A method for effecting weight loss by administering a combination of topiramate and phentermine is provided. The phentermine is generally administered in immediate release form, in a daily dose in...
8895057 Escalating dosing regimen for effecting weight loss and treating obesity  
The present invention is drawn to novel topiramate compositions as well as methods for effecting weight loss, e.g., in the treatment of obesity and related conditions, including conditions...
8889728 Stable pharmaceutical compositions of carvedilol  
A stable solid oral pharmaceutical composition comprising carvedilol or a pharmaceutically acceptable salt thereof, which is packed using a suitable packaging material along with a desiccant. A...
8889161 Microencapsulated compositions and methods for tissue mineralization  
The present invention is directed to compositions, products and methods useful for bone and tooth mineralization. The compositions comprise polymer microcapsules containing aqueous salt solutions....
8889180 Coated drug delivery formulations  
The invention relates generally to methods of making formulations for delivering biological agents to a patient. In one aspect, proliposomal drug-delivery systems for medicaments are provided. In...
8883206 Pharmaceutical composition and administrations thereof  
The present invention relates to pharmaceutical compositions containing a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4 -oxoquinoline-3-carboxamide including...
8883202 Lipid compositions  
Disclosed herein are lipid compositions comprising a cationic lipid of formula (I), a neutral lipid, a sterol and a PEG or PEG-modified lipid, wherein formula (I) is (F). Also disclosed are...