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6746678 |
Method of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with medicaments
This invention defines a novel method for treatment of several neurological diseases and pathophysiologically related symptomology, said diseases including peripheral neuropathies, secondary...
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6746692 |
Modified release pharmaceutical formulation comprising amoxycillin
Bacterial infections may be treated using a high dosage regimen of amoxycillin and potassium clavulanate. Preferably, the dosage is provided by a bilayer tablet.
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6743445 |
Low temperature coatings
A method of coating an active material is provided. The method comprises contacting an active material with a film-forming composition comprising an aqueous dispersion of an amylose-alcohol...
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6740337 |
Bioavailable dosage form of isotretinoin
The present invention relates to a bioavailable pharmaceutical composition of 13-cis vitamin A acid (also known as 13-cis retinoic acid and isotretinoin) and a process for preparing the same....
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6740338 |
Reduced form of Cenzyme Q in high bioavailability stable oral dosage form
The present invention relates to a reduced form of Coenzyme Q also known as ubiquinol in oral dosage form such as a gelatin capsule, preferably a soft gelatin capsule. Compositions according to the...
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6740334 |
Bone resorption suppressing agent
A highly safe bone resorption suppressing agents, which can be used as medicines or admixed to food products or feeds, is produced. Milk-derived basic cystatins and/or milk-derived basic cystatin...
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6737087 |
Composition containing Asiasari Radix extracts for protecting brain cells and improving memory
The present invention discloses that fractions of Asiasari Radix extract have the ability to induce neuroprotection against AMPA (-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid)-induced...
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6733779 |
Method of treating benign prostatic hyperplasia and other benign prostate conditions
Methods of treatment of benign prostatic hyperplasia and reduction of the level of the prostate specific antigen (PSA) of benign prostate conditions are disclosed. The treatment method includes an...
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6733789 |
Multiparticulate bisoprolol formulation
A multiparticulate bisoprolol formulation for once-daily oral administration, each particle of which comprises a core of bisoprolol or a pharmaceutically acceptable salt thereof surrounded by a...
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6730319 |
Pharmaceutical compositions having depressed melting points
The present invention relates to pharmaceutical compositions that contain a solid pharmaceutically active compound having a melting point ≧37° C. and a fatty acid or a fatty acid salt or a...
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6726919 |
Injectable dispersion of propofol
A sterile, injectable homogenized dispersion of micromatrices or microdroplets having a mean diameter from about 50 nm to about 1000 nm comprising about 1% to about 7.5% of propofol, about 1% to...
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6726927 |
Preparation of enteric pharmaceutical dosage forms for omerprazole and lansoprazole
The present invention relates to new stable enteric coated pharmaceutical dosage forms for oral use containing Omeprazole or Lansoprazole, to a formulation and a method for the manufacture of such...
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6726924 |
Oral liposomal delivery system
A liposome-capsule dosage unit system for the delivery of a biologically active material is formed by encapsulating a biologically active materials in liposomes and then placing the liposome...
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6726932 |
Fatty acid-containing composition
The present invention provides a composition for enhancing the pharmacological activity of a water-soluble silicate polymer which comprises the water-soluble silicate polymer and a saturated fatty...
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6726934 |
Micro-particulate and nano-particulate polymeric delivery system
The present invention provides a method of making particles useful in drug delivery, comprising the steps of: contacting polyanionic polymers with cations in a stirred reactor so that polyanions...
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6726931 |
Process for preparing oral sustained-release formulation of felodipine
The present invention relates to a process for producing an oral sustained-release pharmaceutical composition of felodipine. The process includes mixing together felodipine with at least an ionic...
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6723339 |
Oil-free pharmaceutical compositions containing cyclosporin A
The present invention provides a hard gelatine capsule containing a pharmaceutical composition comprising cyclosporin A in a mixture with a surfactant of HLB value at least 10, substantially free...
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6719999 |
Formulations comprising lipid-regulating agents
The present invention is directed to a formulation comprising a lipid-regulating agent dissolved in one or more non-aqueous and/or water-miscible solvents, or optionally, in a premix of one or more...
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6720000 |
Process for producing wet ribavirin pellets
A process for producing wet ribavirin pellets is provided in order to make pharmaceutical dosages of ribavirin. The process is particularly useful as an alternative method for preparing...
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6716450 |
Enhancing protein activity through nanoencapsulation
Nanocapsules useful for encapsulating bioactive molecules such as proteins are disclosed. These nanocapsules are comprised of branched or hyperbranched polymers and copolymers and have a core-shell...
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6716451 |
Formulation and delivery method to enhance antioxidant potency of vitamin E
A formulation to deliver a full-spectrum of Vitamin E isomers for improved antioxidant capacity, bioavailability, dissolution and efficacy. The formulation includes dl-α-tocopheryl acetate or...
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6713533 |
Nanocapsules and method of production thereof
The invention relates to nanocapsules with a size ranging between 50 nm and 10 μm diameter whose envelope layer consists of at least two different, cross-linked polymers P1 and P2. Optionally, a...
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6709674 |
Injectable pamidronate disodium
The invention includes a packaged liquid composition of a pamidronate alkaline salt in a sealed storage vessel having an inner surface which is non-reactive with the pamidronate alkaline salt...
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6709673 |
Microcapsule system for environment-induced release of active agents
A microcapsule system is used to store active agents and release them as a function of specific environmental parameters. The active agents are contained in capsules having a capsule wall...
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6706695 |
Antilipemic formulation
An antilipemic composition, particularly to achieve a lowering of cholesterol levels comprises a biocompatible anionic polysaccharide material containing non-sulphated glucuronic acid.
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6706284 |
Bitterness-reduced oral pharmaceutical composition
The invention relates to an oral pharmaceutical composition which has excellent drug release-controlling ability in the mouth even 5 to 10 minutes after its administration and also has excellent...
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6703042 |
Salts of L-carnitine and lower alkanoyl L-carnitine
The present invention relates to stable, non-hygroscopic salts of L-carnitine and lower alkanoyl L-carnitine endowed with enhanced nutritional and /or therapeutical efficacy with respect to their...
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6703361 |
Method of treating or preventing Type 1 diabetes by oral administration of insulin
Disclosed herein are methods for treating or preventing a disease in mammals having the characteristics of Type 1 diabetes comprising administering insulin or disease suppressive fragments of...
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6703045 |
Composition and method for maintaining blood glucose level
A composition useful for reducing serum glucose levels by an oral controlled release system and a method for treating diabetes in a human being by controlling the blood glucose level (BGL) and...
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6699495 |
Methods for treating multiple sclerosis employing desmethylselegiline
Methods and pharmaceutical compositions for using desmethylselegiline. In particular, the present invention provides novel compositions and methods for using desmethylselegiline for...
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6699500 |
Sustained-release preparation capable of releasing a physiologically active substance
Disclosed is a sustained-release preparation comprising 1) a polymer of lactic acid having a weight-average molecular weight of about 25,000 to about 60,000 and 2) a physiologically active...
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6696091 |
Pharmaceutical composition of topiramate
The invention is directed to a pharmaceutical composition of topiramate an anticonvulsant which is useful for treating epilepsy. More specifically, the present invention provides a solid dosage...
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6696496 |
Low water-soluble venlafaxine salts
Low water soluble salts of venlafaxine, especially venlafaxine maleate, are provided. Such salts can provide a variety of dosage forms including hydrogel-based extended release dosage forms.
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6696088 |
Tamper-resistant oral opioid agonist formulations
Disclosed is an oral dosage form comprising (i) an opioid agonist in releasable form and (ii) a sequestered opioid antagonist which is substantially not released when the dosage form is...
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6696482 |
Formulations for hydrophobic pharmaceutical agents
The present invention features formulations, including liquid, semi-solid or solid pharmaceutical formulations, that improve the oral bioavailability of hydrophobic pharmaceutical agents, such as...
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6696083 |
Vitamin/nutrient dosage regimentation
The efficacy of vitamins and other nutritional agents in treating and preventing various disease states is improved by administering therapeutically effective levels of these agents on a...
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6696084 |
Spray drying process and compositions of fenofibrate
The present invention relates to a novel spray drying process for the preparation of pharmaceutical compositions containing small particles of phospholipid-stabilized fenofibrate. This invention...
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6692767 |
Solid solution beadlet
Disclosed is a beadlet comprising (i) a hydrophobic long chain fatty acid or ester material; (ii) a surfactant; and (iii) a therapeutic agent which in admixture form a solid solution at room...
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6693208 |
Compounds and compositions for delivering active agents
Amino acid derivative as carrier compounds and compositions which are useful in the delivery of active agents are provided. The active agents can be a peptide, mucopolysaccharide, carbohydrate, or...
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6689387 |
Phytochemicals for treatment of mastalgia and endometriosis
New compositions are disclosed that comprise the phytochemical Diindolylmethane (DIM), as well as its precursor, Indole-3-carbinol (I3C), and cogener, 2-(Indol-3-ylmethyl)-3,3′diindolylmethane...
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6689383 |
Chromium-histidine complexes as nutrient supplements
Chromium is an essential element which has been shown to have beneficial effects on carbohydrate and lipid metabolism. Often, dietary intake is suboptimal, and nutritional supplements may not be...
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6685964 |
Opioid analgesics with controlled active substance release
An orally administered preparation with controlled lease of an opioid analgesic in the form of crystals having particle size of 10 μm to 3 mm, preferably of 50 μm to 1 mm, which have at least one...
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6685961 |
Colored gelatin-based formulations and method
The present invention is a process for coloring gelatin-based formulations involving adding a saturated fatty acid to the gelatin-based formulation along with lake pigment, whereby the saturated...
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6685951 |
Administration of dihydroergotamine as a sublingual spray or aerosol for the treatment of migraine
The present invention is an improvement in the treatment of migraine headaches. By administering dihydroergotamine as a sublingual spray or aerosol, major limitations of past treatments are...
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6685962 |
Gastroretentive controlled release pharmaceutical dosage forms
Pharmaceutical gastroretentive drug delivery systems for the controlled release of an active agent in the gastrointestinal tract are disclosed, which comprise: (a) a single- or multi-layered matrix...
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6683103 |
Sulfonamides for treatment of endothelin-mediated disorders
Thienylsulfonamides and their pharmaceutically acceptable derivatives, pharmaceutical compositions, articles of manufacture, combinations, lyophilized powders and methods for the treatment of...
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6680069 |
Low-substituted hydroxypropyl cellulose and process for manufacturing the same
Processes for manufacturing a low-substituted hydroxypropyl cellulose are described that include dipping pulp into an alkaline solution to prepare an alkali cellulose, reacting the alkali cellulose...
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6676964 |
Method for determining the three-dimensional structure of a protein
Microcapsules prepared by encapsulating an aqueous solution of a protein, drug or other bioactive substance inside a semi-permeable membrane by are disclosed. The microcapsules are formed by...
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6677328 |
Method for the prevention of colonic adenomas
Method for the prevention of colonic adenomas in mammals at risk of developing them by administering to such mammals an effective colonic adenoma preventive amount of ursodiol or a pharmaceutically...
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6673368 |
Colonic motor dysfunction remedies comprising aminothiazole derivatives as active ingredients
Remedies effective for the improvement of colonic motor dysfunction such as irritable bowel syndrome, constipation or intestinal atony without causing side effects on the central nerve system....
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