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8182791 |
Formulations for use in inhaler devices
A formulation for an inhaler device comprises carrier particles having a diameter of at least 50 μm and a mass median diameter of at least 175 μm; active particles; and additive material to which i...
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8178078 |
Compositions containing a solvated active agent suitable for dispensing as a compressed gas aerosol
A composition for solvating one or more active agents in an aqueous solution which is suitable for dispensing as a compressed gas aerosol composition is disclosed. The composition includes at least...
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8173107 |
Delivery of antipsychotics through an inhalation route
The present invention relates to the delivery of antipsychotics through an inhalation route. Specifically, it relates to aerosols containing antipsychotics that are used in inhalation therapy. In a...
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8158109 |
Foamable suspension gel
The present subject matter provides foamable suspension gels that foam after release from a container. The foamable suspension gels contain at least one pharmaceutically active agent that is...
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8158110 |
Use of aerosolized cyclosporine for prevention and treatment of pulmonary disease
The present invention relates to methods and compositions for prevention of graft rejection in lung transplant recipients and for treatment of subjects with pulmonary disorders. Specifically, the...
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8142763 |
Pressurized metered dose inhalers (MDI) containing a solution comprising ipratropium bromide, HFA propellant, and co-solvent and comprising a container with a specific internal surface composition and/or lining
The invention relates to pressurized metered dose inhalers (MDIs) in which all or part of the internal surface is stainless steel, anodized aluminum, or lined with an inert organic coating and...
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8137657 |
Carrier particles for use in dry powder inhalers
In a method of producing particles suitable for use as carrier particles in dry powder inhalers, particles (1) of a size suitable for use as carrier particles in dry powder inhalers are treated so...
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8128910 |
Pesticidal aerosol composition
A pesticidal aerosol composition, containing 3-phenoxybenzyl ester compound represented by Formula (I): wherein, X represents a hydrogen atom or a cyano group; Z represents a hydrogen atom or a...
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8124057 |
Propellant-based nanoparticulate dry powder aerosols and method of making
There invention discloses aqueous dispersions of nanoparticulate aerosol formulations, dry powder nanoparticulate aerosol formulation, propellant-based aerosol formulations, methods of using the...
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8119106 |
Foamable iodine compositions
The present invention is related to a foamable composition of matter comprising iodine, water, a foam adjuvant, a surface-active agent and a gelling agent. This foamable composition, which may be...
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8119105 |
Aerosol container and a method for storage and administration of a pre-determined amount of a pharmaceutically active aerosol
The invention relates to an aerosol container for pharmaceutically active aerosols that are to be administered in predetermined amounts and that are supplied in the container in the form of a...
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8114385 |
Oleaginous pharmaceutical and cosmetic foam
The invention relates to stable oleaginous cosmetic or therapeutic foam compositions containing certain active agents, having unique therapeutic properties and methods of treatment using such...
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8101664 |
Urea foam
Provided, among other things, is a delivery module for a non-greasy, water-based urea composition comprising: an aerosol delivery device; within the aerosol delivery device, the urea composition...
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8101160 |
Formulations for use in inhaler devices
A formulation for use in an inhaler device comprises carrier particles having a diameter of at least 50 μm and a mass median diameter of at least 175 μm; fine particles of an excipient material h...
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8097282 |
Methods of administering liquid droplet aerosols of nanoparticulate drugs
There is disclosed an aerosol comprising droplets of an aqueous dispersion of nanoparticles, said nanoparticles comprising insoluble therapeutic or diagnostic agent particles having a surface...
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8088728 |
Airway administration of tissue factor pathway inhibitor in inflammatory conditions affecting the respiratory tract
The present invention provides methods for the local treatment of acute and chronic extravascular pulmonary fibrin deposition and/or reducing unwanted effects associated with systemic...
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8088362 |
Salmeterol superfine formulation
The present invention relates to a pharmaceutical formulation for use in the administration of a long-acting β2-agonist by inhalation. In particular this invention relates to a chemically stable, ...
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8080263 |
Dispersion for pulmonary delivery of a bioactive agent
Stabilized dispersions are provided for the delivery of a bioactive agent. The dispersions preferably comprise a plurality of perforated microstructures dispersed in a suspension medium that...
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8080236 |
Particulate materials
Embodiments of the invention relate to particles of active substances, methods for preparing the particles, formulations containing the particles, and metered dose inhalers containing the particles...
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8071073 |
Compositions comprising azelastine and methods of use thereof
The present invention provides pharmaceutical compositions comprising azelastine, or a pharmaceutically acceptable salt or ester thereof including azelastine hydrochloride, and optionally one or...
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8071074 |
Preventing airway mucus production by administration of EGF-R antagonists
Hypersecretion of mucus in the lungs is inhibited by the administration of an epidermal growth factor receptor (EGF-R) antagonist. The EGF-R antagonist may be in the form of a small organic...
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8062626 |
Stable pharmaceutical budesonide preparation for producing propellant-free aerosols
The invention relates to ethanol-containing pharmaceutical preparations for the production of propellant-free aerosols.
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8062627 |
Methods and compositions for treating pulmonary disorders using optically pure (R,R)-formoterol
A method and composition are disclosed utilizing the pure (R,R) isomer of formoterol, which is a potent bronchodilator with reduced adverse effects, a low incidence of the development of tolerance...
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8034371 |
Intranasal compositions
The present invention provides compositions for the intranasal administration of zolpidem or a pharmaceutically acceptable salt thereof. Preferred compositions of the invention are in the form of...
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8030362 |
Compositions for treatment of ear disorders and methods of use thereof
The present invention relates to compositions and methods useful for the treatment of ear disorders, administered to a treated ear in the form of a foam or a mousse. Administering a medicament in...
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8029768 |
Treatment of respiratory diseases
A pharmaceutical composition for pulmonary delivery comprises glycopyrrolate in a controlled release formulation, wherein, on administration, the glycopyrrolate exerts its pharmacological effect...
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8021649 |
Continuous spray scalp therapy and dispensing systems for same
A spray delivery system in combination with a scalp medication is provided which includes a portable container having a gas imperious container wall, a pressure source disposed within the...
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8003081 |
Method for improvement of tolerance for therapeutically effective agents delivered by inhalation
A method for improvement of tolerance for therapeutically effective agents delivered by inhalation comprising a pretreatment of a patient with a nebulized lidocaine or a lidocaine-like compound...
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8003080 |
Delivery of drug amines through an inhalation route
The present invention relates to the delivery of drug amines through an inhalation route. Specifically, it relates to aerosols containing drug amines that are used in inhalation therapy. In one...
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8001961 |
Container for inhalation anesthetic
A container for liquid inhalation anesthetics, more particularly, an aluminum container that is suitable for storing halogenated inhalation anesthetics is described.
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7998463 |
Targeted delivery of lidocaine and other local anesthetics and a method for treatment of cough, asthma and tussive attacks
An anti-tussive nebulized solution for targeted delivery of lidocaine into conducting and central airways. A method for treatment of cough and tussive attacks or episodes using said lidocaine...
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7994224 |
Sprayable aerosol paint composition with 3-iodo-2-propynyl butyl carbamate fungicide and a vinyl toluene alkyd resin
An aerosol paint composition includes an alkyd resin; one or more solvents; an organoclay; an anti-settling wax; a dispersing agent; one or more pigments; a drying agent; an anti-skinning agent; a...
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7988952 |
Delivery of drug esters through an inhalation route
The present invention relates to the delivery of drug esters through an inhalation route. Specifically, it relates to aerosols containing drug esters that are used in inhalation therapy. In a...
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7981401 |
Diuretic aerosols and methods of making and using them
Described herein are diuretic condensation aerosols and methods of making and using them. Kits for delivering a condensation aerosol are also described. The diuretic aerosols typically comprise...
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7959617 |
Devices and methods for delivering active agents to target sites
The subject invention provides novel, inexpensive, and highly effective methods and devices for convenient and effective wound irrigation. In one embodiment the subject invention provides a...
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7947257 |
Method of intranasal administration of granisetron
Compositions are provided for the intranasal administration of granisetron or a pharmaceutically acceptable salt thereof. Preferred compositions are in the form of an aqueous solution. Optionally,...
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7943118 |
Aerosolized fosfomycin/aminoglycoside combination for the treatment of bacterial respiratory infections
A fosfomycin plus tobramycin combination formulation for delivery by aerosolization is described. The concentrated fosfomycin tobramycin combination formulation containing an efficacious amount of...
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7914770 |
Formulation for a metered dose inhaler using hydro-fluoro-alkanes as propellants
An improved suspension formulation for use in a metered-dose inhaler having a hydro-fluoro-alkane propellant is described, the improvement being the controlled addition of a small quantity of water.
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7897646 |
Use for budesonide and formoterol
The invention provides the use of formoterol and budesonide in the treatment of chronic obstructive pulmonary disease.
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7863241 |
Compositions for treatment and prevention of pulmonary conditions
The invention provides compositions and methods for treating pulmonary conditions and for reducing the negative effects of pulmonary inflammation. Such compositions and methods employ protease...
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7842283 |
Generation of therapeutic microfoam
A method for producing a microfoam suitable for use in scleropathy of blood vessels comprises introducing a physiologically acceptable blood-dispersible gas into a container (1) holding an aqueous...
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7842282 |
Generation of therapeutic microfoam
A method for producing a microfoam suitable for use in scleropathy of blood vessels comprises introducing a physiologically acceptable blood-dispersible gas into a container (1) holding an aqueous...
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7829107 |
Foamable pharmaceutical compositions and methods for treating a disorder
Novel compositions of matter comprising a foamable delivery system are provided. Novel methods for treating a disease, disorder, or condition using the novel compositions are further provided....
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7820145 |
Oleaginous pharmaceutical and cosmetic foam
The invention relates to stable oleaginous cosmetic or therapeutic foam compositions containing certain active agents, having unique therapeutic properties and methods of treatment using such...
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7790145 |
Respiratory dispersion for metered dose inhalers
A respiratory dispersion is provided for the pulmonary delivery of at least two bioactive agents. The dispersion comprises a propellant suspension medium having dispersed therein a plurality of...
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7776315 |
Pharmaceutical compositions based on anticholinergics and additional active ingredients
A pharmaceutical composition comprising an anticholinergic and at least one additional active ingredient selected from among corticosteroids, dopamine agonistes, PDE-IV inhibitors, NK1-antagonists,...
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7766013 |
Aerosol generating method and device
A method and device are provided to generate an aerosol having a desired particle sizes, i.e., from molecular to about 10 microns, which can be used to effectively deliver a physiologically active...
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7763278 |
Nanoparticulate polycosanol formulations and novel polycosanol combinations
The present invention is directed to nanoparticulate compositions comprising one or more polycosanols. The polycosanol particles of the composition have an effective average particle size of less...
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7758886 |
Pharmaceutical aerosol composition
Sterile compositions for administration as aerosols are described. They contain an active agent which is poorly water-soluble, a non-ionic surfactant acomponent and a phospholipid component. The...
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7758888 |
Composition exhibiting enhanced formulation stability and delivery of topical active ingredients
A therapeutic, cosmetic or cosmeceutic composition for topical application, capable of stabilizing an active ingredient and delivering the active ingredient, comprising a plurality of microcapsules...
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