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7018621 |
Delivery of rizatriptan or zolmitriptan through an inhalation route
The present invention relates to the delivery of compounds for the treatment of migraine and headache through an inhalation route. Specifically, it relates to aerosols containing rizatriptan or...
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7018619 |
Delivery of alprazolam, estazolam midazolam or triazolam through an inhalation route
The present invention relates to the delivery of alprazolam, estazolam, midazolam or triazolam through an inhalation route. Specifically, it relates to aerosols containing alprazolam, estazolam,...
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7018657 |
Particulate composition
Nanoparticles are prepared from a colloidal system comprising a continuous phase and micelles, the micelles comprising surfactant material. A microemulsion is formed by admixing the colloidal...
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7018620 |
Delivery of beta-blockers through an inhalation route
The present invention relates to the delivery of atenolol, pindolol, esmolol, propranolol, or metoprolol through an inhalation route. Specifically, it relates to aerosols containing atenolol,...
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7014841 |
Delivery of antiemetics through an inhalation route
The present invention relates to the delivery of antiemetics through an inhalation route. Specifically, it relates to aerosols containing antiemetics that are used in inhalation therapy. In a...
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7014840 |
Delivery of sumatriptan, frovatriptan or naratriptan through an inhalation route
The present invention relates to the delivery of anti-migraine compounds through an inhalation route. Specifically, it relates to aerosols containing sumatriptan, frovatriptan, or naratriptan that...
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7011819 |
Delivery of rizatriptan or zolmitriptan through an inhalation route
The present invention relates to the delivery of headache and anti-migraine compounds through an inhalation route. Specifically, it relates to aerosols containing that are used in inhalation...
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7011820 |
Delivery of compounds for the treatment of Parkinsons through an inhalation route
The present invention relates to the delivery of antiparkinsons drugs through an inhalation route. In a method aspect of the present invention, an antiparkinsons drug is administered to a patient...
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7011818 |
Carrier particles for use in dry powder inhalers
A powder for use in a dry powder inhaler includes active particles and carrier particles for carrying the active particles. The powder further includes additive material ( 4 ) on the surfaces of...
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7008615 |
Delivery of anti-migraine compounds through an inhalation route
The present invention relates to the delivery of anti-migraine compounds through an inhalation route. Specifically, it relates to aerosols containing lidocaine, verapamil, diltiazem, isometheptene,...
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7005121 |
Delivery of compounds for the treatment of migraine through an inhalation route
The present invention relates to the delivery of a migraine headache drug through an inhalation route. Specifically, it relates to aerosols containing a migraine headache drug that are used in...
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6998391 |
Method for treating diseases associated with abnormal kinase activity
Methods are provided for treating diseases associated with abnormal activity of kinases. The method comprises: administering a DNA methylation inhibitor to the patient in therapeutically effective...
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6998110 |
Buccal, polar and non-polar spray or capsule
Buccal aerosol sprays or capsule using polar and non-polar solvent have now been developed which provide biologically active compounds for rapid absorption through the oral mucosa, resulting in...
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6994842 |
Aerogel powder therapeutic agents
Drugs in the form of very fine highly porous aerogel particles are delivered to a patient via inhalation. The aerogel particles are either an aerogelized form of a pharmaceutical or deposited upon...
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6991779 |
Compositions for treatment or prevention of bioterrorism
Compositions containing biologically active molecules encapsulated in self-assembling, diketopiperazine microspheres (TECHNOSPHEREs™) and methods for making and administering such compositions...
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6984404 |
Methods for preparing coated drug particles and pharmaceutical formulations thereof
Disclosed are methods using pulsed laser ablation to prepare coated drug particles of uniform size and thickness. The coated drug particles ranged in size from several nanometers to several...
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6982075 |
Use of pulmonary surfactant
The invention describes the novel use of pulmonary surfactant preparations in the artificial respiration of patents with toxic oxygen concentrations.
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6979437 |
Pulmonary delivery in treating disorders of the central nervous system
A method for treating a disorder of the central nervous system includes administering to the respiratory tract of a patient a drug which is delivered to the pulmonary system, for instance to the...
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6977087 |
Aerodynamically light particles for pulmonary drug delivery
Improved aerodynamically light particles for delivery to the pulmonary system, and methods for their preparation and administration are provided. In a preferred embodiment, the aerodynamically...
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6974568 |
Treatment for cough
The invention discloses the existence of cannabinoid receptors in the airways, which are functionally linked to inhibition of cough. Locally acting cannabinoid agents can be administered to the...
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6974803 |
Pharmaceutical combination
The present invention relates to a combination comprising (a) an adenosine A 2a receptor agonist as defined herein and (b) an adrenergic β2 receptor agonist, for simultaneous, sequential or...
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6969521 |
Aerosol insect repellent composition having low VOC content and method of applying same to the skin
Disclosed is an aerosol insect repellent composition. The composition has (a) an amount of an insect repellent effective to repel insects when applied to the skin and (b) a cosmetically-acceptable...
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6967017 |
Formulations of steroid solutions for inhalatory administration
The present invention relates to optimized formulations of antiinflammatory steroids for nebulisation and a process for the preparation thereof. More particularly, the invention relates to...
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6964759 |
Formulations containing an anticholinergic drug for the treatment of chronic obstructive pulmonary disease
Formulations for the administration through pressurized metered dose aerosol inhalers containing an anticholineric drug in solution in a hydrofluorocarbon propellant, a cosolvent and a low...
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6962691 |
Topical spray compositions
A topical, medicinal spray composition is provided comprising a drug or combination of drugs in a carrier which, when sprayed on a surface, forms a film. The composition comprises at least one...
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6960337 |
Methods and compositions for treating benign gynecological disorders
An improvement in a method of treating benign gynecological disorders is described. In the method, treatment of a benign gynecological disorder with a composition comprised of a gonadotropin...
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6958142 |
Nasal spray formulation and method
A nasal spray formulation for use in female contraception or in the treatment of benign gynecological disorders is described. The nasal preparation is comprised of a GnRH compound and an estrogenic...
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6955824 |
Inhalation composition containing lactose pellets
This invention relates to a pharmaceutical composition which is suitable for the administration of medicaments by inhalation. In particular, the pharmaceutical composition comprises microfine...
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6946117 |
Stabilized preparations for use in nebulizers
Stabilized dispersions are provided for the delivery of a bioactive agent to the respiratory tract of a patient. The dispersions preferably comprise a stabilized colloidal system which may comprise...
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6946141 |
As-needed administration of tricyclic and other non-SRI antidepressant drugs to treat premature ejaculation
A method is provided for treatment of premature ejaculation by administration of an antidepressant drug selected from tricyclic antidepressants, tetracyclic antidepressants, MAO inhibitors,...
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6939534 |
Method to treat pulmonary hypoplasia in the newborn
A method of treating pulmonary hypoplasia in infants has been developed, wherein epidermal growth factor (EGF) is administered to the pulmonary system of an infant in need of treatment thereof. The...
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6936244 |
Use of bacterial phage associated lysing enzymes for treating streptococcal infections of the upper respiratory tract
A composition for treatment of bacterial infections of the eye is disclosed which comprises a lytic enzyme composition specific for the infecting bacteria, and a carrier for delivering said lytic...
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6932962 |
Aerosol drug formulations containing hydrofluoroalkanes and alkyl saccharides
Aerosol formulations suitable for use in pressurised metered dose inhalers comprise a hydrofluoroalkane propellant, an medicament for inhalation and a surfactant which is a a C 8 –C 16 fatty...
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6930097 |
Matrix metalloproteinase and tumor necrosis factor inhibitors
A compound of formula 1-[3,4-dihydroxy-5-(2-hydroxyethyl)tetrahydrofuran-2-yl]pryi
midine-2,4(1H,3H)-dione has inhibitory effects of matrix metalloproteinase-2 (gelatinase A) enzyme and binding of...
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6926908 |
Formulation for inhalation
Microparticles, obtainable by spray-drying a substantially pure solution of a therapeutic agent, consist essentially of the agent having its therapeutic activity when administered to the lung. In a...
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6921527 |
Composition for pulmonary administration comprising a drug and a hydrophobic amino acid
According to the subject invention, dispersible dry powder pharmaceutical-based compositions are provided, including methods for their manufacture and dry powder dispersion devices. A dispersible...
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6919069 |
Aerosol formulation containing particulate formoterol, propellant and polar cosolvent
A pharmaceutical aerosol formulation comprising (i) particulate medicament, (ii) 1,1,1,2-tetrafluoroethane, 1,1,1,2,3,3,3,-heptafluoro-n-propane or a mixture thereof as propellant, and (iii) 0.01...
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6913805 |
Controlled release ampule containing a fumigant
The present invention provides an apparatus and method for controlled release of a fumigant into a wooden structure to prevent decay of that structure. According to the present invention, a...
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6902720 |
Cyclic peptide structures for molecular scale electronic and photonic devices
The present invention discloses a family of cyclic peptide monomers and supramolecular cyclic peptide structures comprising chromophore residues which possess electronic and electro-optic...
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6893628 |
Aerosol formulations containing P134a and particulate medicament
A pharmaceutical formulation comprising (i) one or more particulate medicaments, and (ii) 1,1,1,2-tetrafuoroethane as propellant, which formulation contains less than 0.0001% w/w surfactant based...
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6893657 |
Solid dose delivery vehicle and methods of making same
The present invention encompasses a solid dose delivery vehicle for ballistic administration of a bioactive material to subcutaneous and intradermal tissue, the delivery vehicle being sized and...
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6890517 |
Inhalable formulation of a solution containing a tiotropium salt
A liquid, propellant-free pharmaceutical preparation comprising:
(a) a first active substance comprising a tiotropium salt, in a concentration based on tiotropium of between 0.0005% and 5%...
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6890518 |
Compositions of chemically modified insulin
The present invention provides active, hydrophilic polymer-modified derivatives of insulin. The insulin derivatives of the invention are, in one aspect, suitable for delivery to the lung and...
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6887459 |
Aerosol composition comprising formoterol
The use of a dry powder comprising (A) formoterol, or a pharmaceutically acceptable salt or solvate thereof, or solvate of said salt, and (B) a pharmaceutically acceptable particulate diluent or...
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6881398 |
Therapeutic dry powder preparation
A therapeutic dry powder preparation and a method of administering such a preparation are disclosed for effectively de-aggregating and dispersing into air a dose of medication powder in an...
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6881757 |
Aerosol biliquid foam
Pressurized mixtures of propellant gasses and liquid surface or air treating materials are disclosed. The liquid materials are in the form of a dispersion which is a biliquid foam with a thickener,...
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6881725 |
Method for treating pain
The present invention is directed to a method of treating pain. The method comprises administering to a subject a pharmaceutical composition comprising an effective amount of a P2X receptor...
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6875449 |
Crystal structure
A process for the production of crystals with controlled surface smoothness, size, shape and degree of crystallinity, compositions comprising such crystals, and the use of certain crystals,...
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6869613 |
Sprayable insecticidal compositions having enhanced efficacy
There is provided a sprayable insecticidal composition having significantly increased efficacy which comprises an effective amount of an insecticide; an abrasive; a low level of a surfactant; an...
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6867199 |
Dinucleoside polyphosphate compositions and their therapeutic use
The present invention relates to certain novel dinucleoside polyphosphates of general Formulae I, II and III, and formulations thereof which are selective ligands of the P2Y purinergic receptors....
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