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7615238 |
Plaster for the treatment of dysfunctions and disorders of nails, comprising sertaconazole
The present invention relates to plasters for prophylaxis and/or treatment of a dysfunction or disorder of nails, especially onychomycosis, onychocryptosis, nail psoriasis, melanonychia striata,...
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7615237 |
Percutaneously absorbable preparations
Percutaneously absorbable preparations (preferably nonaqueous ones, particularly matrix-type patches or ointment), containing salt-form acidic drugs and characterized by being improved in the...
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7615236 |
Medical dressing for application and maintenance of medication on body tissue
A medical method and dressing for application, and maintenance of medication on healthy, damaged diseased or infected living tissue. Medication is applied to body tissue and then coated with a...
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7611727 |
Pharmaceutical composition for transdermal or transmucous administration
The present invention relates to a novel pharmaceutical composition for transdermal or transmucous administration of at least one active substance, and comprising especially a fatty acid as a...
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7611723 |
Stinging cells expressing an exogenous polynucleotide encoding a therapeutic, diagnostic or a cosmetic agent and methods compositions and devices utilizing such stinging cells or capsules derived therefrom for delivering the therapeutic, diagnostic or cosmetic agent into a tissue
A stinging cell comprising an exogenous polynucleotide capable of expressing a therapeutic, cosmetic or diagnostic agent in the stinging cell is provided.
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7608282 |
Transdermal granisetron
Adhesive patches for the transdermal administration of granisetron, comprise an acrylic adhesive containing non-acidic nucleophilic moieties which substantially increase flux of granisetron across...
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7588784 |
Use of onion extracts to prevent and treat acute and chronic cardiac and vascular complications and their sequelae, as well as to resolve hematomas
Onions ( Allium Cepa and its close relatives, as opposed to Allium Sativum ) contain potent coagulation modulators, as well as platelet inhibitors. Clinical, in vivo and in vitro testing confirms...
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7585519 |
Esters of L-carnitine or alkanoyl L-carnitines useful as cationic lipids for the intracellular delivery of pharmacologically active compounds
Esters of L-carnitine and alkanoyl L-carnitines are described which can be used as cationic lipids for the intracellular delivery of pharmacologically active compounds. New esters of L-carnitine...
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7574256 |
Iontophoretic device and method of delivery of active agents to biological interface
An iontophoresis device includes: an active electrode element operable to provide an electrical potential; an inner active agent reservoir comprising: a first compartment having a diluent; a second...
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7560121 |
Transdermal therapeutic system with a highly effective neuroleptic agent
A transdermal therapeutic system consisting of a backing layer, at least one active substance-containing matrix layer, which may at the same time possess pressure-sensitive adhesive properties, as...
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7556824 |
Transdermal patch composition for treating vascular diseases characterized by nitric oxide insufficiency
The present invention provides novel transdermal patch comprising a therapeutic amount of a hydralazine compound and at least one of isosorbide dinitrate and isosorbide mononitrate in...
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7556823 |
Fentanyl suspension-based silicone adhesive formulations and devices for transdermal delivery of fentanyl
Silicone adhesive formulations are provided, in which fentanyl particles are suspended in one or more solvated silicone adhesives. The formulations can be used for manufacturing improved,...
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7527802 |
Vaccine for transcutaneous immunization
A vaccine delivered by transcutaneous immunization provides an effective treatment against infections by pathogens such as, for example, enterotoxigenic Escherichia coli (ETEC) and/or for...
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7521065 |
Compositions for the treatment and prevention of cancer
Compositions are provided for the topical treatment of cancer consisting of lotions, creams, sprays, suppositories or slow-release transdermal patches containing lipid-soluble, skin-penetrating...
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7507769 |
Treatment and prevention of benign breast disease with 4-hydroxy tamoxifen
The present invention provides methods for treating and preventing benign breast disease by administering 4-hydroxy tamoxifen to a patient. When percutaneously administered to a patient's breasts,...
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7504114 |
Preparations for percutaneous absorption
Preparations for percutaneous absorption comprising a basic drug or its salt dissolved in a liquid component and having an enhanced percutaneous absorbability and a safety to the skin, i.e., the...
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7485623 |
Reduction of breast density with 4-hydroxy tamoxifen
A method of treatment comprises administering 4-hydroxy tamoxifen percutaneously to a patient having dense breast tissue. The 4-hydroxy tamoxifen may be formulated in a hydroalcoholic gel or an...
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7479132 |
Patch material for ionic medicine administration
The present invention discloses a patch for use in administration of an ionic medicine into a living body by infiltration of the ionic medicine into the living body through the living body surface...
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7470433 |
Formulations for transdermal or transmucosal application
The present invention relates generally to formulations for transdermal or transmucosal administration of an active agent such as estradiol. The invention is a substantially malodorous-free and...
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7459171 |
Method for the improvement of transport across adaptable semi-permeable barriers
The invention relates to a method, a kit and a device for controlling the flux of penetrants across an adaptable semi-permeable porous barrier, the method comprising the steps of: preparing a...
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7456331 |
Composition for cushions, wounds dressings and other skin-contacting products
A skin-contacting adhesive composition is described which has improved initial tack, long-term adhesion, water uptake and translucency characteristics and may be prepared by melt extrusion. Uses of...
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7456236 |
Adhesive for percutaneous absorption, adhesive composition for percutaneous absorption and preparation for percutaneous absorption
To offer adhesives for percutaneous absorption, adhesive compositions for percutaneous absorption and preparations for percutaneous absorption which show high ability to dissolve drugs and to...
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7449307 |
Raised surface assay plate
The assay plate includes a substrate having an substrate surface and at least one raised pad extending from the substrate surface. The raised pad includes a substantially planar sample receiving...
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7438926 |
Methods for inhibiting decrease in transdermal drug flux by inhibition of pathway closure
This invention relates to a method for inhibiting a decrease in the transdermal flux of an agent that is being transdermally delivered or sampled over a prolonged period of time wherein the...
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7438203 |
Dermal penetration enhancers and drug delivery systems involving same
The invention relates to a method for treatment or prophylaxis of a disease or condition in an animal comprising administering to a mucosal membrane of said animal in need of such treatment a...
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7435380 |
Pseudo-plastic or thixotropic liquid deodorant product for ostomy pouches
A pseudo-plastic or thixotropic carrier having anti-malodorous components dissolved or suspended therein is sprayed on the internal surfaces of an ostomy bag or pouch. The viscoelastic properties...
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7413748 |
Transdermal buprenorphine to treat pain in sickle cell crisis
A specific dosage regimen of buprenorphine achieves pain relief from painful episodes due to sickle cell disease. The dosage regimen comprises administering to a patient in need of pain relief from...
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7413747 |
Transdermal therapeutic system for treating Parkinsonism
A transdermal therapeutic system (TTS) comprises a silicone-based polymer adhesive system having distributed therein (−)-5,6,7,8-tetrahydro-6-[propyl-[2-(2-thienyl)ethyl]amino
]-1-naphthalenol...
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7399462 |
Protectant for UV-induced skin damage
The present invention provides a method for protecting against UV radiation-induced skin damage. Specifically, compositions including dapsone are administered to provide UV protection. The dapsone...
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7390500 |
Transdermal therapeutic system (TTS) with fentanyl as a active ingredient
The invention relates to a transdermal therapeutic systems with fentanyl or an analogous fentanyl derivative as active ingredient. In order to prevent inadvertent overdosage by uncontrolled release...
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7387789 |
Transdermal delivery of non-steroidal anti-inflammatory drugs
The present invention provides a transdermal drug delivery system which comprises: a therapeutically effective amount of a non-steroidal anti-inflammatory drug; at least one dermal penetration...
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7387788 |
Pharmaceutical compositions of nicotine and methods of use thereof
The present invention comprises non occlusive compositions for transdermal delivery of nicotine, and more particularly pharmaceutically acceptable salts thereof, and methods of making same. The...
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7387783 |
Keratotic plug remover
The invention relates to a keratotic plug remover comprising, as active ingredients, (A) a polymer having sulfonic or sulfate groups or having salts thereof and (B) a nonionic polymer, and a pack...
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7384651 |
Transdermal therapeutic system comprising a reservoir type pressure sensitive adhesive layer and a back layer with uni-directional resilience
A transdermal therapeutic system (TTS), in particular a patch, is described, comprising:
a detachable protective layer; a pressure-sensitive adhesive reservoir layer; and a backing layer...
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7384650 |
Skin permeation enhancement composition for transdermal hormone delivery system
A transdermal hormone delivery system (THDS) is disclosed. The THDS is useful for control of fertility and as therapy for a variety of diseases and conditions treatable by robust delivery of...
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RE40359 |
Polymer blends as biodegradable matrices for preparing biocomposites
The present invention provides bioerodable constructs for controlled release of bioactive materials. In a preferred mode, the constructs may be utilized adjacent to a biological surface. The...
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7378108 |
Percutaneous absorption preparation of compound having angiotensin II antagonistic activity
The present invention provides a percutaneous absorption preparation which comprises a compound having angiotensin II antagonistic activity and which allows the compound to permeate through the...
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7378097 |
Use of penetration enhancers and barrier disruption methods to enhance the immune response of antigen and adjuvant
A transcutaneous immunization system where the topical application of an adjuvant and an antigen or nucleic acid encoding for an antigen, to intact skin induces a systemic or mucosol antibody...
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7375139 |
Transdermal method and apparatus
A transdermal patch for the treatment of iron deficiency including a drug reservoir layer containing an hematinic substance; a rate-controlling membrane secured to said reservoir layer; and a...
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7374777 |
Oriented biopolymeric membrane for meningeal tissue repair
A cell occlusion sheet membrane adapted for repairing a damaged meningeal tissue. The sheet membrane contains a layer of cross-linked, oriented biopolymeric fibers that has a thickness of 0.1 mm to...
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7344733 |
Matrix controlled transdermal therapeutic system for the use of pramipexole and ropinirole
The invention relates to an active-ingredient-containing, matrix-controlled transdermal therapeutic system for the use of pramipexole, ropinirole, pharmaceutically acceptable salts thereof or...
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7338673 |
Medicated patch for treating bee and wasp stings
A medicated patch for extracting bee/wasp sting toxins from the human skin includes a flexible substrate layer that has a planar adhesive surface and an annular shape. An annular receptacle is...
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7338665 |
Methods compositions and devices utilizing stinging cells/capsules for delivering a therapeutic or a cosmetic agent into a tissue
A delivery device including at least one stinging capsule and methods of use are described.
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7335379 |
Transdermal pharmaceutical formulation for minimizing skin residues
This invention relates to novel transdermal or transmucosal pharmaceutical formulation which reduces the occurrences of contamination of other individuals and the transference to clothing of the...
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7335378 |
Therapeutic system containing an active substance for the application on the skin which contains at least two polymerous layers
Active substance-containing therapeutic system for application on the skin, comprising at least two polymer-containing layers, characterized in that the-polymers used for the different layers...
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7332180 |
Transdermal therapeutic system for administering non-steroidal antiphlogistic agents containing carboxyl groups, and a method for the production of the same
A transdermal therapeutic system (TTS) with a content of at least one active substance from the group of the carboxyl group-containing non-steroidal antirheumatics, which has a backing layer ( 1 ),...
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7329417 |
Medical dressing comprising an antimicrobial silver compound
A medical dressing comprising a complex of silver and being capable of releasing antimicrobial silver ion activity, the complex comprising silver ion, a transition element of Group IV of the...
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7323452 |
Method for the accelerated in vivo removal of ethanol
A method for accelerating the process of removing ethanol from the blood through the use of certain additives that accelerate the metabolic oxidation of ethanol, and others which in addition act as...
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7323191 |
Transdermal warfarin system
Composition of matter for application to a body surface or membrane to administer warfarin by permeation through the body surface or membrane, the composition comprising warfarin to be...
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7316817 |
Method and device for topical delivery of therapeutic agents to the skin
A composite sheet for delivering therapeutic agents to the skin and method of use is disclosed. The composite sheet comprises a flexible porous polymer for holding and releasing the therapeutic...
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