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6110481 Controlled release device based on aqueous-organic partitioning in porous membranes  
A novel controlled release device employing microporous membranes with or without a nonporous coating and aqueous-organic partitioning of the bioreactive substances to be delivered is provided....
6106857 Fragranced cosmetic product for removal of keratotic plugs from skin pores  
A cosmetic product is provided for removing keratotic skin plugs. The product is a strip sealed for storage having from 0.0001 to 2% fragrance within the atmosphere of the sealed pouch. The strip...
6106856 Transdermal delivery of calcium channel blockers, such as nifedipine  
A transdermal formulation of dihydropyridine calcium antagonists and specifically nifedipine, nimodipine and nitrendipine. The calcium antagonists are dispersed in a mixed liquid. The mixed liquid...
6093419 Compliance verification method and device in compulsory drug administration  
A substance countering agent especially for an abused drug or alcohol or a contraceptive agent is contained in a flexible adherent sheet or patch used to achieve the transdermal delivery of the...
6090404 Estradiol penetration enhancers  
An active substance-containing patch for the controlled release of estradiol or its pharmaceutically acceptable derivatives alone or in combination with gestagens from a backing layer, an active...
6090403 Inhalation therapy decongestant with foraminous carrier  
A vaporizable decongestant is supported and stabilized on a flexible foraminous carrier composed typically of open-cell plastic foam, cloth or other fibrous material such as nonwoven fabric. The...
6090405 Buprenorphine percutaneous absorption preparation  
Disclosed is a buprenorphine percutaneous absorption preparation comprising a backing having formed on one side thereof a pressure-sensitive adhesive layer containing at least one of buprenorphine...
6086912 Topical drug delivery system  
A drug delivery system for the topical administration of medication or other therapeutic material wherein the prior art peripheral layer of adhesive surrounding the active drug delivery area of the...
6086911 Drug delivery device  
6080421 Transdermal therapeutic system identified without printing inks  
The invention refers to a transdermal therapeutic system for the delivery of active agents to the human body. The backing layer consists of common pharmaceutical plastic layer laminates which...
RE36754 Devices using silicone pressure sensitive adhesives containing organic wax  
Hot-melt silicone pressure sensitive adhesive compositions containing organic waxes, methods of using the compositions and devices made using the compositions are disclosed. The hot-melt silicone...
6077528 Percutaneous preparation  
The present invention relates to a percutaneous preparation comprising an adhesive layer formed on at least one side of a substrate, the layer containing an acrylic copolymer,...
6077527 Enhancer tolerant pressure sensitive adhesives for transdermal drug delivery  
Pressure sensitive adhesive compositions for use in transdermal drug delivery systems comprising an adhesive composition which is tolerant to plasticization by cutaneous penetration enhancers...
6074665 Transdermal therapeutic system for administering active agents to the human body via the skin  
A transdermal therapeutic system having a layered structure, comprising a backing layer (1) and at least one active substance-containing matrix layer (2), for storage purposes being placed onto a...
6074660 Absorbable polyoxaesters containing amines and/ or amido groups  
The present invention describes a polyoxaester copolymers containing amines and/or amido groups and blends thereof with other polymers that may be used to produce surgical devices such as sutures,...
6072100 Extrudable compositions for topical or transdermal drug delivery  
An effective and convenient medicament delivery system comprising novel extrudable compositions. The preferred compositions of the invention contain a thermoplastic water-soluble polymer selected...
6071531 Transdermal patch and method for administering 17-deacetyl norgestimate alone or in combination with an estrogen  
Compositions and methods for preventing ovulation in a woman are provided, as well as compositions and methods for female hormone replacement therapy. The compositions can be administered by the...
6068853 Temporally controlled drug delivery systems  
A delivery mechanism and device for the passive periodic release of a drug or an active ingredient which avoids the need for external power sources and/or electronic controllers. By taking...
6063399 Adhesive binders for dermal or transdermal therapy systems  
An adhesive binder for dermal or transdermal therapy systems consists of the following components: (a1) 55-99.9 wt. % of a (meth)acrylate copolymer of a structural (meth)acrylate or a functional...
6042845 Anti fungal treatment of nails  
There is disclosed a method for the treatment of fungal diseases in nails, which comprises the topical administration to the nail and, if desired, also to the surrounding skin, of (1) a sulfhydryl...
6033684 Compositions and methods for wound management  
A wound dressing composition and a method of using that composition to enhance the natural process of topical wound healing. The composition comprises at least one adhesive ingredient that adheres...
6024974 Composition and methods for transdermal delivery of acid labile drugs  
A transdermal composition and related method are described. Specifically, the transdermal composition is substantially free of gestodene or substantially free of isopropyl myristate and...
6024975 Method of transdermally administering high molecular weight drugs with a polymer skin enhancer  
A high molecular weight drug is transdermally administered by applying a polymer skin enhancer and a drug active to the skin of the patient. The drug active has a molecular weight of above 50...
6019988 Methods and compositions for enhancing skin permeation of drugs using permeation enhancers, when drugs and/or permeation enhancers are unstable in combination during long-term storage  
The invention provides methods and means for enhancing the epidermal, transdermal and dermal permeation of a topically applied pharmacologically active agent (e.g., a drug or medicament) which has...
6013276 Transdermal matrix system  
A novel transdermal matrix system for the percutaneous delivery of a hormone, including a carrier and an adhesive matrix, is disclosed. The matrix includes (a) 39-61 parts by weight of an...
6011061 Therapeutic methods and preparations using rubidium ions  
Various methods of treating the musculoskeletal, neural and respiratory disorders in a patient are disclosed wherein a preparation containing rubidium ions, preferably in the form of rubidium...
6010714 Non-thermogenic heat dissipating biomedical adhesive compositions  
A biocompatible monomer composition includes at least one monomer, which forms a medically acceptable polymer, and an effective amount of at least one heat dissipating agent sufficient to reduce...
6010715 Transdermal patch incorporating a polymer film incorporated with an active agent  
Devices for the controlled release of an active agent to the skin or mucosa of a host are disclosed, which devices are laminates of a backing layer and a monolithic carrier layer formed from a melt...
6007835 Transdermal matrix system  
A novel transdermal system for the percutaneous delivery of a hormone, including a carrier and an adhesive matrix, is disclosed. The matrix includes (a) 20-50 parts by weight of a...
6007836 Transdermal vasodilator  
A vasodilator delivery system is provided for producing and maintaining the erection of a male penis during intercourse. The vasodilator is contained in a transdermal patch. The transdermal patch...
6004577 Enhanced electrotransport of therapeutic agents having polybasic anionic counter ions  
Improved electrotransport of therapeutic agents which include agent cations and polybasic anionic counterions. Improved electrotransport is obtained by treating the therapeutic agent with a...
6004969 Transdermal delivery of buprenorphine preparations  
Buprenorphine is a potent analgesic agent, it has been shown to be as effective as morphine. The main clinical application of buprenorphine is to relief postoperative pains or for patients in the...
6004578 Permeation enhances for transdermal drug delivery compositions, devices and methods  
The present invention is directed to the transdermal administration of at least one drug together with a suitable amount of a permeation enhancer comprising monoalkyl ethers of polyethyleneglycol...
6001390 Formulations for transdermal delivery of pergolide  
Composition of matter for application to a body surface or membrane to administer pergolide by permeation through the body surface or membrane, the composition comprising pergolide to be...
6002961 Transdermal protein delivery using low-frequency sonophoresis  
Applications of low-frequency (20 KHz) ultrasound enhances transdermal transport of high-molecular weight proteins. This method includes a simultaneous application of ultrasound and protein on the...
6001380 Medicated applicator sheet for topical drug delivery  
The present invention provides a method for applying a plurality, preferably two, of dermatological agents to the skin from a single dispensing and applicator sheet comprising a plurality of...
RE36420 Percutaneous preparation of tulobuterol  
A percutaneous preparation of tulobuterol is disclosed, comprising a support having thereon a base layer comprising a pressure-sensitive adhesive containing tulobuterol, the pressure-sensitive...
5993849 Hydrophilic adhesive and binder for medications  
The invention relates to an adhesive and binder for dermal or transdermal therapy systems, that includes (a) 85-99.9 weight % of (meth)acrylate copolymer of structural and functional monomers,...
5989586 Two-phase matrix for sustained release drug delivery device  
A two-phase hydrophilic drug-containing matrix for use in transdermal drug delivery patches in which one phase is a continuous hydrophobic polymer phase which optionally includes a hydrophobic...
5989585 Transdermal therapeutic system (TTS) containing vitamin E for the treatment of drug dependency  
The invention relates to a transdermal therapeutic system (TTS) for the administration of active agents for substitution treatment of drug dependency or drug addiction.
5985317 Pressure sensitive adhesive matrix patches for transdermal delivery of salts of pharmaceutical agents  
A method of transdermally or transmucosally delivering a hydrophilic salt form of a drug with a water-based pressure sensitive hydrophobic adhesive matrix patch optionally containing a permeation...
5985300 Delivery of skin benefit agents via adhesive strips  
A cosmetic product is provided for delivery of skin actives through adhesive strips which concurrently remove keratotic plugs from skin pores. The product is a strip including a flexible substrate...
5985990 Use of pendant free-radically polymerizable moieties with polar polymers to prepare hydrophilic pressure sensitive adhesive compositions  
Cross-linked, hydrophilic pressure sensitive adhesive compositions, (meth)acrylate-functional polar polymers which serve as precursors to them, and medical products using such adhesives are...
5980933 Transdermal formulation of xanomeline  
The present invention provides a method for treating Alzheimer's Disease using a xanomeline transdermal formulation. The invention provides desired transdermal xanomeline patch formulations.
5972376 Transdermal system of tacrine/selegilin-plaster  
The invention relates to a plaster for transdermal application with an outer covering or backing layer, a self-adhesive matrix or a reservoir and a removable protective liner or release layer, the...
5968533 Skin care compositions and methods  
Skin care compositions and methods are provided for improving the appearance of skin affected by aging, photodamage and/or oxidative stress. Specifically, adhesive materials containing cosmetically...
5968919 Hormone replacement therapy drug formulations for topical application to the skin  
Topical alcoholic or aqueous alcoholic gels containing testosterone, progesterone, estradiol or other hormones have enhanced penetration through skin by including in the formulation...
5965154 Adhesive matrix type transdermal patch and method of manufacturing same  
The invention provides adhesive matrix type transdermal patches and methods for manufacturing the patches. More specifically, the invention utilizes ordinary, prefabricated, commercially available,...
5962012 Cholinergic antagonist patch  
Scopolamine is a folksy cholinergic antagonist, and is used by parasympathetic nerves in autonomic nervous neurons as an anti-motion sickness drug or an anti-emesis drug. Since the human body most...
5962011 Device for delivery of dermatological ingredients  
A novel device and method for delivering a liquid containing an active ingredient to a treatment site on the skin is disclosed. The device is useful for treating lesions or abnormal skin features...