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9040626 Nanofibers and morphology shifting micelles  
The invention discloses novel morphology shifting micelles and amphiphilic coated metal nanofibers. Methods of using and making the same are also disclosed.
9034368 Method of topically applying glycopyrrolate solution using absorbent pad to reduce sweating  
This invention relates to a convenient and safe product and method of applying glycopyrrolate topically in order to reduce excessive sweating in localized areas for those who suffer from this...
9034355 Materials for modulating biological responses and methods of making  
A polymeric composition capable of releasing nitric oxide and modulating biological responses comprises a biocompatible polymer and S-nitrosated thiol bonded to the biocompatible polymer. The...
9034369 Article comprising calcium for reducing the production of TSST-1  
Articles comprising one or more calcium salts are provided. The articles can contain one or more calcium salts in an amount effective to reduce the production of TSST-1 by at least about 50% when...
9034367 Articles for tissue regeneration with biodegradable polymer  
The invention is to articles made from extracellular matrix sheets that encase biodegradable polymeric material. Methods of healing wounds or regenerating tissue at sites of defect by placing said...
9028862 Enhanced moisture barrier immediate release film coating systems and substrates coated therewith  
The present invention is directed to immediate release film coating systems for use on oral dosage forms such as compressed tablets and other orally-ingestible substrates which have improved...
9023382 Medicament carrier composition and method of forming a film therefrom  
A medicament carrier composition includes a medicament and a polymer component including a polyvinylpyrrolidone having a weight average molecular weight of at least 700,000 g/mol. The medicament...
9017711 Soft tissue wrap  
Compositions and methods for treating and healing injured soft tissues such as tendons and ligaments are provided. The composition may be a wrap comprising human collagen in the form of a sheet....
9017405 Skin substitute and wound dressing with variable pore sizes  
An improved skin substitute is presented comprised of a silicone layer backed up with a woven nylon fabric layer, the silicone layer possessing a regular pattern of slits that permit the porosity...
9017718 Dual and single layer dosage forms  
Provided is a dual-release, dual-adhesiveness flexible thin film dosage form comprising: a quick-release subfilm comprising an admixture of polymer, which comprises predominantly highly...
9017717 Bandage for facilitating transdermal respiration and healing  
A bandage includes a reservoir filled with a perfluorochemical fluid, saturated with oxygen. Oxygen passes through a permeable membrane to the skin or wound to promote healing, and carbon dioxide...
9005653 Transdermal delivery of hormones with low concentration of penetration enhancers  
The present invention relates to a patch comprising a drug-containing layer with low content of hormones, such as gestodene, and optionally an estrogen (e.g. ethinyl estradiol). Upon administering...
9006182 Light activated composite tissue adhesives  
A light activated collagen-flavin composite layer incorporating riboflavin is applied as treatment for infected lesions. These composites have also been found to be strong tissue adheives that are...
8999379 Transparent transdermal nicotine delivery devices  
A transparent transdermal delivery device for delivering nicotine which has an Opacity Index of less than 48.6%.
8999297 Hemostatic agent  
A generally non-acidic hemostatic agent, having a relatively neutral pH comprising a magnesium compound, such as a magnesium chloride, a magnesium sulfate and/or a magnesium acetate based...
8999376 Tissue patch  
Tissue patches and associated systems and methods are described. Certain embodiments are related to inventive systems and methods in which tissue patches can be made quickly and robustly without...
8992945 Supramacromolecular polymer complexes providing controlled nitric oxide release for healing wounds  
A bio-adhesive supramacromolecular complex of the general formula: wherein R1 is independently selected from the group consisting of an alkane unsubstituted or substituted with alkoxy groups; R2...
8993829 Device and method for securing sutures and the like  
A bandage and method for securing a tension member comprising a central body and a plurality of tabs disposed about the central body. A tension member may be disposed across or through a slit or...
8986730 Methods for sealing a vascular puncture  
Methods for sealing a puncture communicating with a blood vessel are provided that include introducing a porous carrier formed from lyophilized hydrogel or other material into the puncture. The...
8980278 Bio-functionalized stimulus-responsive dissolvable PEG-hydrogels  
The present invention is directed to a bio-functionalized stimulus-responsive dissolvable PEG-hydrogel. This inventive stimulus-responsive dissolvable PEG-hydrogel comprises a matrix of...
8974814 Layered drug delivery polymer monofilament fibers  
The present invention is directed generally to a layered polymeric monofilament fiber drug delivery device, where each layer of the device can contain a different polymer, drug, additive, or any...
8974815 Fibrous membrane for biomedical application based on poly(ester-amide)s  
Electrospun biodegradable poly(ester-amide) fabric is especially suitable as a scaffold for tissue engineering and to incorporate drug for burn or wound healing treatment to accelerate healing, or...
8974816 Water resistant patch preparation  
The present invention provides a water resistant patch preparation having a central part and a peripheral part, which preparation is comprised of a support and an adhesive layer comprising a drug,...
8968771 Articles and methods for applying antimicrobial protection  
Among other things, there is disclosed an improved wet wipe or similar substrate for applying an antibacterial/antibiotic layer to surfaces or other items. A wipe substrate is impregnated with a...
8968774 Preparation and composition of meloxicam transdermal drug delivery system  
A composition for transdermal permeation and a preparation method are disclosed. The composition including meloxicam as an active ingredient and further including at least one permeation enhancing...
8962027 Materials comprising water-soluble polymer particles and methods of making and using them  
One aspect of the invention relates to new materials for storing, protecting, selectively releasing, and applying active ingredients (e.g. pharmaceuticals and other chemicals). In certain...
8962013 Multi-layered transdermal system with triazine UV absorber  
The UV-stable solid transdermal therapeutic system (TTS) with UV absorber for photosensitive active pharmaceutical ingredients has a backing layer (1), at least one active ingredient-containing...
8962035 Variable density tissue graft composition and methods of making and using the same  
Disclosed are tissue graft compositions made of materials having different densities, methods of making, and methods of treatment for restoring tissues in a patient.
8956637 Medical device applications of nanostructured surfaces  
This invention provides novel nanofiber enhanced surface area substrates and structures comprising such substrates for use in various medical devices, as well as methods and uses for such...
8957076 Wound healing  
The present invention relates to the use of p38 MAP kinase inhibitors and p38 MAP kinase inhibition to promote wound healing.
8951549 Method for the reduction of the concentration of amines and salts thereof  
The invention relates to a method for reducing the concentration of amines and salts thereof, wherein the amines have the general chemical formula I R1R2R3N and the salts have the formula II...
8951551 Multiribbon nanocellulose as a matrix for wound healing  
The present invention includes compositions and methods for the integration of a non-allergenic nanocellulose into a wound bed. The composition may be formed into a wide variety of implants, e.g.,...
8951599 Wound dressing  
A wound dressing and a method of making the wound dressing is described herein. The wound dressing is formed of an absorbent substrate formed of one or more layers and a low-adherence layer...
8945593 Orally ingested metabolic enhancer in oral thin film container  
An orally ingestible energy-boosting device is provided for facilitating a temporary metabolic increase in a user. The device comprises a small container filled with an energy-enhancing substance....
8945536 Stem cell sheet for tissue repair  
Disclosed is a cell sheet for tissue repair and bio-artificial tissue engineering. The cell sheet comprises treated stem cell embedded in its self-secreted extracellular matrix (ECM) and formed a...
8940323 Tissue products having a cooling sensation when contacted with skin  
Wiping products, such as facial tissues, contain a temperature change composition that can provide a cooling sensation when contacted with the skin of a user. The temperature change composition,...
8938898 Devices for the identification of medical products  
Devices in which components of medical kits are carried are identifiable by means other than by the naked eye. The means for identification is attached to or integral with the device and may...
8936825 Method and system for forming a pharmaceutical product directly onto a packaging surface  
The present invention relates to a method for forming a pharmaceutical product, such as a dissolvable film dosage form, onto a surface. Particularly, the present invention relates to a method of...
8932623 Protective wound dressing device for oral and pharyngeal space  
The present invention provides a wound dressing comprising a tessellated water-soluble molding matrix comprised of a polymer selected from the group consisting of polyvinyl alcohol, gelatin, and...
8932596 Method of treating eosinophilic esophagitis  
The present invention relates to the treatment of EE. More specifically, the invention relates to a new method of treating EE through the epicutaneous route. In particular, the method of the...
8932665 Method for preventing the crystallisation of pharmaceuticals in a polymer film  
The invention relates to a method for preventing the crystallization of a pharmaceutical in a polymer film, wherein the solvent-containing coating compound, which comprises a matrix-forming...
8920867 Methods of forming self-supporting films for delivery of therapeutic agents  
The present disclosure relates to self-supporting films for delivery of a therapeutic agent containing at least one hydrophobic polymer and at least one therapeutic agent. Methods of forming the...
8920830 Temperature reducing, healing wound dressing  
The present invention relates to wound dressings having a wound contacting layer that contains a wound healing composition and which is adapted to maintain a temperature different from ambient,...
8920831 Lidocaine-containing hydrogel patch  
A lidocaine-containing hydrogel patch comprising: a support layer; anda adhesive layer stacked on a surface of the support layer, whereinthe adhesive layer comprises at least one selected from the...
8916185 Immobilizing particles onto surfaces  
A method for immobilizing micro-particles, nano-particles or combinations thereof onto a surface is disclosed. The method includes distributing the micro-particles, nano-particles or combinations...
8911772 Release liner or protective sheet having a slit covered by another layer for use in adhesive laminates  
The invention relates to laminate segments equipped or coated with an adhesive matrix, particularly transdermal therapeutic systems having formulations strongly tending to leak adhesive. The...
8911771 Fluid application device and method  
The present invention provides a device and a method for application of topical antiseptics. The device comprises a handle; a base coupled to the handle; and a substantially hydrophilic foam...
8911773 Peelable pouch for transdermal patch and method for packaging  
A peelable pouch comprises a substantially flat enclosure formed by first and second opposing flexible plies. A seat extends along at least a portion of a perimeter of the opposing plies. A flat,...
8911770 Dissolvable dietary supplement strip and methods for using the same  
A strip, which is both edible and dissolvable, is provided comprising a film and a dosage of at least 2% of the reference daily intake (RDI) of at least one dietary supplement for malnutrition or...
8906282 Micro-structured and nano-structured surfaces on biodegradable polymers  
In embodiments of the present invention, a biodegradable/biodegradable polymer film may be used as a scaffold for tissue engineering scaffolds for engineering organized organs, such as vascular...