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7524512 |
Composition and method for the prevention and relief of the symptoms of an incompetent or patulous Eustachian tube
A composition and methods for the treatment of symptoms due to disorders, disease or trauma that impairs normal function of die Eustachian tube and alters vital structures or tissues of the middle...
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7294345 |
Otorhinological delivery device
The invention relates to an otorhinological delivery device comprising at least one pharmaceutically active agent. According to the invention the device comprises a core comprising said at least...
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6793932 |
Preparation for veterinary use
A veterinary composition comprising at least one keratolytic and cerumenilytic cleaning agent, a at least one bactericide agent, at least one yeast control agent and at least one anti-irritant and...
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6743439 |
Ophthalmic compositions containing copolymers of sulfonated styrene and maleic anhydride
Aqueous pharmaceutical solution compositions preserved with a cationic preservative and comprising a cationic drug and a sulfonated styrene/maleic anhydride copolymer are disclosed. The...
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6726904 |
Method for transmitting acoustic waves
The invention relates to the use of a gel mass based on reaction products of polyols and polyisocyanates, wherein the polyol component consists of one or more polyols with hydroxyl numbers below...
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6548554 |
Ionic aqueous composition containing levomenthol
A composition for relieving a sensation of respiratory discomfort and/or for promoting natural regeneration of mucous membranes of the nasal cavity. The composition contains levomenthol at a...
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6432440 |
Pectin compositions and methods of use for improved delivery of drugs to mucosal surfaces
Liquid pharmaceutical compositions for administration to a mucosal surface, comprising a therapeutic agent and a pectin with a low degree of esterification are described. Such compositions gel, or...
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6423694 |
Method of treating otitis media with uridine triphosphates and related compounds
A method of promoting drainage of congested middle ear fluid in a subject in need of such treatment is disclosed. The method comprises administering to the middle ear of the subject a uridine...
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6395295 |
Use of surface active agent for the manufacture of a medicament for treatment of disorders of the middle ear
The invention relates to the treatment of serous otitis media (glue ear). A medicament is disclosed which comprises a surface active phospholipid (SAPL) which is instilled as a powder into the...
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6361526 |
Antimicrobial tympanostomy tube
An antimicrobial tympanostomy tube used to alleviate bacteriostatic infections following myringotomy which is compatible with otologic tissue associated with the middle ear. The tube is formed from...
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6333045 |
Aqueous liquid pharmaceutical composition comprised of gatifloxacin
There is provided an aqueous liquid pharmaceutical composition which comprises Gatifloxacin (chemical nomenclature: (±)-1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methy
l-1-piperazi...
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6306845 |
Method for treating demyelinating disease
The present invention provides a method for treating a demyelinating disease in a subject which includes administering to the subject a therapeutically effective amount of a high affinity...
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6235315 |
Stable, pulverulent lycopene formulations, comprising lycopene having a degree of crystallinity of greater than 20%
The invention relates to stable, pulverulent lycopene formulations, comprising lycopene having a degree of crystallinity of greater than 20%, processes for their preparation and their use as an...
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6156293 |
Moistening preparation
The present invention relates to preparations alleviating the symptoms caused by drying of the mucous membranes of the body. The preparations contain trimethylglycine as an active agent. The...
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6093417 |
Composition to treat ear disorders
A topical ear composition that uses penetration enhancers to diffuse the therapeutic agents through the tympanic membrane into the middle and inner ear for the purpose of reducing the inflammation...
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6017554 |
Composition for treating abnormal conditions of the epithelium of bodily orifices
A stable solution cream, salve, or spray composition containing activated stabilized chlorine dioxide and phosphates, such as disodium hydrogen phosphate, sodium dihydrogen phosphate, trisodium...
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6004575 |
Use of (meth) acrylic acid/maleic acid copolymers for improving mucosal permeability
(Meth)acrylic acid/maleic acid copolymers for improving mucosal permeability and pharmaceutical compositions containing them are described.
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5945115 |
Polymeric compositions useful as controlled release implants
The invention is directed to an improved system for controlled release of biologically active materials and to a liquid composition for its formation. The liquid composition is composed of a...
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5935592 |
Method for treating vaginitis and endometriosis
A stable solution, cream, salve, or spray composition containing activated chlorine dioxide and phosphates, such as disodium hydrogen phosphate, sodium dihydrogen phosphate, trisodium phosphate,...
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5935594 |
Process and device for treating and healing a tissue deficiency
An improved method or process and device for treating and healing a bone void is disclosed, and in particular a method employing a surfactant for efficiently incorporating a biologically active...
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5902575 |
Method for treating the epithelium of bodily orifices with chlorine dioxide and a phosphate compound
A stable solution, cream, salve, or spray composition containing chlorine dioxide and a phosphate, such as disodium hydrogen phosphate, sodium dihydrogen phosphate, trisodium phosphate, and sodium...
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5874099 |
Methods for making immunoisolatary implantable vehicles with a biocompatible jacket and a biocompatible matrix core
A method of forming an implantable and retrievable immunoisolatory vehicles is disclosed, the method comprising the steps of first forming a core comprising a volume of at least 1 μl and at least...
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5871767 |
Methods for treatment or prevention of neurodegenerative conditions using immunoisolatory implantable vehicles with a biocompatible jacket and a biocompatible matrix core
A method for treatment of a neurodegenerative condition in a patient comprising implanting in the patient at least one immunoisolatory vehicle comprising a corc comprising a volume of at least 1...
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5843930 |
Method of treating otitis with ciprofloxacin-hydrocortisone suspension
The invention is directed to a method of treating otitis which comprises introducing an antibacterially-effective amount of a composition comprising a non-ototoxic, topical, otic pharmaceutic...
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5834001 |
Methods for making immunoisolatory implantable vehicles with a biocompatiable jacket and a biocompatible matrix core
A method of forming an implantable and retrievable immunoisolatory vehicle is disclosed, the method comprising the steps of first forming a jacket of biocompatible thermoplastic or hydrogel, and...
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5834003 |
Method for oxidatively consuming volatile sulfur compounds at bodily orifices
A method for oxidatively consuming volatile sulfur compounds selected from the group consisting of dimethylsulfide, hydrogen sulfide, and methylmercaptan at the epithelial barrier of the rectal,...
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5800829 |
Methods for coextruding immunoisolatory implantable vehicles with a biocompatible jacket and a biocompatible matrix core
A method of making an immunoisolatory vehicle comprised of a core comprising living cells dispersed in a biocompatible matrix is disclosed, the cells being capable of secreting a biologically...
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5747061 |
Suspension of loteprednol etabonate for ear, eye, or nose treatment
The invention provides novel compositions of matter for delivering water-insoluble steroid drugs suitable for therapeutic use. The invention also provides stable aqueous suspensions of...
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5744166 |
Drug delivery compositions
Compositions for delivery of pharmacologically active agents and methods for their administration are provided. In one embodiment, the compositions include a complex of a polycationic polymer and a...
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5700478 |
Water-soluble pressure-sensitive mucoadhesive and devices provided therewith for emplacement in a mucosa-lined body cavity
Water-soluble pressure-sensitive adhesives include a water-soluble polymer that is made tacky at room temperature by addition of a water-soluble plasticizer that is miscible with the polymer....
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5637314 |
Topical and systemic application of buspirone or derivatives thereof for treating atopic dermatitis
A method for treating atopic dermatitis, hayfever, asthma and pruritis that includes topical or systemic application of an effective amount of buspirone or a buspirone derivative or its...
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5618550 |
Method for treatment of abnormal conditions of the epithelium of bodily orifices
A stable solution, cream, salve, or spray composition containing activated stabilized chlorine dioxide and phosphates, such as disodium hydrogen phosphate, sodium dihydrogen phosphate, trisodium...
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5554388 |
Systemic drug delivery compositions comprising a polycationi substance
A composition for administration to the mucosa comprises a pharmacologically active compound and a polycationic substance. The polycationic substance is preferably DEAE-dextran or chitosan and the...
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5540930 |
Suspension of loteprednol etabonate for ear, eye, or nose treatment
The invention provides novel compositions of matter containing water-insoluble steroid drugs suitable for therapeutic use. The invention provides stable aqueous suspensions of water-insoluble...
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5503848 |
Spongy material consisting essentially of hyaluronic acid or its derivatives, and its use in microsurgery
The present invention relates to a new spongy material consisting essentially of hyaluronic acid or its derivatives. The characteristics of the new pharmaceutical preparations consist in assuring...
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5492937 |
Gel-forming liquid carrier composition
A carrier composition that is a liquid at or below room temperature forms a high viscosity layer or gel at body temperature, which comprises a water-soluble, nonionic cellulose ether having a cloud...
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5489435 |
Composition for treatment of abnormal conditions of the epithelium of bodily orifices
A stable solution, cream, salve, or spray composition containing activated stabilized chlorine dioxide and phosphates, such as disodium hydrogen phosphate, sodium dihydrogen phosphate, trisodium...
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5468811 |
Hydrophilic composite polymer articles formed from a settable paste comprising a mixture of hydrophilic polymer and unsaturated monomer
Hydrophilic composite polymer articles are provided which comprise at least one hydrophilic polymer in a powder form and one or more liquid components of which at least one is hydrophilic and which...
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5401806 |
Biocompatible mouldable polymeric material
A biocompatible moldable curable polymer/monomer system capable of curing at ambient temperatures to provide an elastomer product while producing a lower exotherm than previously used systems. The...
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5350580 |
Device and method for extended delivery of pharmacologically active agents to the ear
A device useful for the treatment of infections of the middle ear in a prophylactic manner. A preferred device involves the use of a biodegradable support incorporating a therapeutically active...
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5178873 |
Essential fatty acid treatment
A method of inhibiting phospholipase A2 in the control of inflammation, wherein delta-6,9,12,15-octadecatetraenoic acid (stearidonic acid) and/or delta-8,11,14,17-eicosatetraenoic acid is...
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5156842 |
Liquid suspension for oral administration
A non-aqueous pharmaceutical liquid suspension having improved bioavailability for oral administration comprises an active ingredient suspended in an edible, non-aqueous carrier vehicle such as an...
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5130137 |
Continuous delivery of luteinizing hormone releasing hormone compositions in combination with sex steroid delivery for use in treating benign ovarian secretory disorders
This invention is directed to a delivery system and a method useful for the treatment of benign ovarian secretory disorders in female mammals by administering an LHRH composition. The method...
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5126127 |
Stabilized PVP-I solutions
Povidone-Iodine (PVP-I) solutions stable according to U.S.P. standards and a method for preparing the same are disclosed. The PVP-I solution includes a microbicidal effective amount of available...
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5093127 |
Preparation of FR115224 substrate for parenteral administration
A cyclic peptide designated FR115224, administered parenterally in a cyclodextrin carrier, which exhibits antiallergic activity.
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5057319 |
Pharmaceutical compositions of cimetidine
The present invention provides a pharmaceutical granule composition comprising cimetidine and, as a granulating agent and taste-masking agent, an ester of a polyhydroxy compound, and where desired...
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4994273 |
Solubility modulated drug delivery device
A solubility modulated drug delivery device for controlled release of a therapeutically active ingredient into an environment of use is disclosed. The device comprises a core composition of a...
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4968633 |
Mucosal allergo-test and relevant device for the determination of specific and total IgE
An allergological test for detecting an allergic condition, said test consisting in contacting the mucous membrane direct with the allergen or the anti-IgE antibody linked to a solid phase, so that...
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4923699 |
Eye treatment suspension
An ophthalmic treatment system is provided which includes three-dimensional particles of bioerodible material suspended in a liquid carrier or ointment carrier having a pH acceptable to the eye....
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4923700 |
Artificial tear suspension
An artificial tear suspension system is provided which includes bioerodible mucin-type particles, lipid-type material and aqueous-type material. The bioerodible mucin-type particles are suspended...
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